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Aliases for TANGO2 Gene

Aliases for TANGO2 Gene

  • Transport And Golgi Organization 2 Homolog (Drosophila) 2 3
  • C22orf25 3 4
  • Transport And Golgi Organization Protein 2 Homolog 3
  • Chromosome 22 Open Reading Frame 25 2

External Ids for TANGO2 Gene

Previous HGNC Symbols for TANGO2 Gene

  • C22orf25

Summaries for TANGO2 Gene

GeneCards Summary for TANGO2 Gene

TANGO2 (Transport And Golgi Organization 2 Homolog (Drosophila)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TANGO2 Gene

Genomics for TANGO2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TANGO2 Gene

20,017,000 bp from pter
20,065,926 bp from pter
48,927 bases
Plus strand

Genomic View for TANGO2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TANGO2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TANGO2 Gene

No data available for Regulatory Elements for TANGO2 Gene

Proteins for TANGO2 Gene

  • Protein details for TANGO2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transport and Golgi organization protein 2 homolog
    Protein Accession:
    Secondary Accessions:
    • A8MUE9
    • B7WNV6
    • B7Z583
    • B7Z730
    • D3DX23
    • Q8IW05
    • Q8NAL0
    • Q8TCS0
    • Q96M16

    Protein attributes for TANGO2 Gene

    276 amino acids
    Molecular mass:
    30937 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TANGO2 Gene

neXtProt entry for TANGO2 Gene

Proteomics data for TANGO2 Gene at MOPED

Post-translational modifications for TANGO2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TANGO2 Gene

Domains for TANGO2 Gene

Protein Domains for TANGO2 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q6ICL3
  • Belongs to the Tango2 family.
genes like me logo Genes that share domains with TANGO2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TANGO2 Gene

Function for TANGO2 Gene

Phenotypes for TANGO2 Gene

genes like me logo Genes that share phenotypes with TANGO2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TANGO2 Gene

Localization for TANGO2 Gene

Gene Ontology (GO) - Cellular Components for TANGO2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with TANGO2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TANGO2 Gene

Pathways for TANGO2 Gene

SuperPathways for TANGO2 Gene

No Data Available

Interacting Proteins for TANGO2 Gene

Gene Ontology (GO) - Biological Process for TANGO2 Gene


No data available for Pathways by source for TANGO2 Gene

Transcripts for TANGO2 Gene

Unigene Clusters for TANGO2 Gene

Transport and golgi organization 2 homolog (Drosophila):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TANGO2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TANGO2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c
SP1: - -
SP2: -
SP3: - - - -
SP4: - - - - -
SP5: - -
SP6: -
SP7: -
SP9: - - - -

Relevant External Links for TANGO2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TANGO2 Gene

mRNA expression in normal human tissues for TANGO2 Gene

mRNA differential expression in normal tissues according to GTEx for TANGO2 Gene

This gene is overexpressed in Whole Blood (5.7).

Protein differential expression in normal tissues for TANGO2 Gene

This gene is overexpressed in Spleen (9.8), Peripheral blood mononuclear cells (9.4), and Platelet (6.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TANGO2 Gene

SOURCE GeneReport for Unigene cluster for TANGO2 Gene Hs.474233

genes like me logo Genes that share expressions with TANGO2: view

Expression partners for TANGO2 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TANGO2 Gene

Orthologs for TANGO2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TANGO2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TANGO2 35
  • 85.27 (n)
  • 82.97 (a)
  • 85 (a)
  • 79 (a)
(Canis familiaris)
Mammalia TANGO2 35
  • 86.59 (n)
  • 90.58 (a)
  • 71 (a)
(Mus musculus)
Mammalia Tango2 35
  • 84.3 (n)
  • 87.68 (a)
Tango2 16
Tango2 36
  • 88 (a)
(Rattus norvegicus)
Mammalia Tango2 35
  • 83.57 (n)
  • 86.96 (a)
(Monodelphis domestica)
Mammalia TANGO2 36
  • 76 (a)
(Pan troglodytes)
Mammalia TANGO2 36
  • 92 (a)
(Gallus gallus)
Aves C15H22ORF25 35
  • 68.36 (n)
  • 73.45 (a)
  • 73 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.20456 35
tango2 35
  • 66.91 (n)
  • 68 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC68627 35
(Danio rerio)
Actinopterygii tango2 35
  • 66.18 (n)
  • 65.07 (a)
tango2 36
  • 64 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8435 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002962 35
  • 48.76 (n)
  • 36.57 (a)
fruit fly
(Drosophila melanogaster)
Insecta Tango2 35
  • 46.64 (n)
  • 31.4 (a)
Tango2 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea R186.1 35
  • 41.35 (n)
  • 32.06 (a)
R186.1 36
  • 31 (a)
Y80D3A.9 36
  • 27 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 26 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G38260 35
  • 44.27 (n)
  • 32.43 (a)
(Oryza sativa)
Liliopsida Os09g0323500 35
  • 47.75 (n)
  • 34.75 (a)
Species with no ortholog for TANGO2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TANGO2 Gene

Gene Tree for TANGO2 (if available)
Gene Tree for TANGO2 (if available)

Paralogs for TANGO2 Gene

genes like me logo Genes that share paralogs with TANGO2: view

No data available for Paralogs for TANGO2 Gene

Variants for TANGO2 Gene

Sequence variations from dbSNP and Humsavar for TANGO2 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs165604 -- 20,047,232(+) tgttt(G/T)ttttt intron-variant
rs174875 -- 20,051,632(+) ggatc(A/G)cttga intron-variant
rs174876 -- 20,055,847(+) CACAT(C/T)GCTAG intron-variant
rs174877 -- 20,057,896(+) TGGCA(C/T)CCTCG intron-variant, utr-variant-3-prime
rs366148 -- 20,054,086(+) GTGGT(C/T)GGCAC intron-variant

Relevant External Links for TANGO2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TANGO2 Gene

Disorders for TANGO2 Gene

No disorders were found for TANGO2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TANGO2 Gene

Publications for TANGO2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TANGO2 Gene

Sources for TANGO2 Gene

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