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TANC2 Gene

protein-coding   GIFtS: 49
GCID: GC17P061086

Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil...

  Search for TANC2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing
21 2
     Protein TANC22
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Domain-Containing
Protein 22 3
     Putative Ankyrin-Repeat Containing Protein2
KIAA16363 5     Rolling Pebbles Homolog B2
Rolling Pebbles Homolog B (Drosophila)1     rols2
ROLSA2     KIAA11483

External Ids:    HGNC: 302121   Entrez Gene: 261152   Ensembl: ENSG000001709217   OMIM: 6150475   UniProtKB: Q9HCD63   

Export aliases for TANC2 gene to outside databases

Previous GC identifers: GC17P058397 GC17P058625 GC17P056455


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TANC2 Gene:
TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) is a protein-coding gene. An important paralog of this gene is ANKS3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TANC2 gene promoter:
         TBP   SRF   Pbx1a   Nkx2-2   SRF (504 AA)   RORalpha2   RORalpha1   FOXJ2 (long isoform)   TFIID   FOXJ2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TANC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TANC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.3   Ensembl cytogenetic band:  17q23.2   HGNC cytogenetic band: 17q23.3

TANC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TANC2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P061086:  view genomic region     (about GC identifiers)

Start:
61,086,898 bp from pter      End:
61,505,067 bp from pter
Size:
418,170 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TANC2_HUMAN, Q9HCD6 (See protein sequence)
Recommended Name: Protein TANC2  
Size: 1990 amino acids; 219650 Da
Sequence caution: Sequence=CAB92314.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAB92314.1; Type=Frameshift; Positions=1221;
Secondary accessions: Q9HAC3 Q9NW88 Q9NXY9 Q9ULS2
Alternative splicing: 4 isoforms:  Q9HCD6-1   Q9HCD6-2   Q9HCD6-3   Q9HCD6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TANC2: NX_Q9HCD6

Explore proteomics data for TANC2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TANC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079461.2  
    ENSEMBL proteins: 
     ENSP00000387593   ENSP00000374171   ENSP00000463062   ENSP00000463959   ENSP00000462109  
     ENSP00000464181  

    TANC2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TANC2
    GenScript Custom Purified and Recombinant Proteins Services for TANC2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TANC2

     
    Search eBioscience for Proteins for TANC2 

    TANC2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals TANC2 Antibodies
    Abcam antibodies for TANC2
    Cloud-Clone Corp. Antibodies for TANC2
    Search ThermoFisher Antibodies for TANC2
    Search LSBio for Antibodies for TANC2

    TANC2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TANC2
    Cloud-Clone Corp. CLIAs for TANC2
    Search eBioscience for ELISAs for TANC2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing
    TTC: Tetratricopeptide (TTC) repeat domain containing

    Selected InterPro protein domains (see all 6):
     IPR011990 TPR-like_helical
     IPR027417 P-loop_NTPase
     IPR020683 Ankyrin_rpt-contain_dom
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9HCD6

    ProtoNet protein and cluster: Q9HCD6

    UniProtKB/Swiss-Prot: TANC2_HUMAN, Q9HCD6
    Similarity: Belongs to the TANC family
    Similarity: Contains 11 ANK repeats
    Similarity: Contains 3 TPR repeats


    Find genes that share domains with TANC2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TANC2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TANC2:
     Large nuclei 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tanc2):
     mortality/aging 

    Find genes that share phenotypes with TANC2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TANC2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TANC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TANC2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TANC2

    miRNA
    Products:
        
    miRTarBase miRNAs that target TANC2:
    hsa-mir-335-5p (MIRT017079), hsa-mir-99b-5p (MIRT044171), hsa-mir-92a-3p (MIRT049132)

    Block miRNA regulation of human, mouse, rat TANC2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TANC2 (see all 270):
    hsa-miR-124* hsa-miR-579 hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-146a hsa-miR-3916 hsa-miR-761 hsa-miR-520b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TANC2
    Predesigned siRNA for gene silencing in human, mouse, rat TANC2

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for TANC2 (see all 5)
    OriGene ORF clones in mouse, rat for TANC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TANC2 (NM_025185)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TANC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TANC2

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for TANC2
    Browse ESI BIO Cell Lines and PureStem Progenitors for TANC2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TANC2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    cytoskeleton1
    mitochondrion1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TANC2
    Interactions:

        Search GeneGlobe Interaction Network for TANC2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for TANC2 (Q9HCD62, 3 ENSP000003875934) via UniProtKB, MINT, STRING, and/or I2D (see all 563)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAEP622582, 3MINT-7947479 I2D: score=1 
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    DOCK5Q9H7D02, ENSP000002764404MINT-7947479 STRING: ENSP00000276440
    ABCF1Q8NE712MINT-7947479
    ABCF3Q9NUQ82MINT-7947479
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--

    Find genes that share ontologies with TANC2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TANC2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TANC2 gene (3 alternative transcripts): 
    NM_015623.2  NM_030658.2  NM_025185.3  

    Unigene Cluster for TANC2:

    Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
    Hs.410889  [show with all ESTs]
    Unigene Representative Sequence: NM_025185
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000424789(uc002jal.4 uc010wpe.2 uc002jao.4) ENST00000389520
    ENST00000580068 ENST00000580466 ENST00000581424 ENST00000583356 ENST00000583545(uc002jam.1)
    ENST00000581143(uc002jan.1) ENST00000583016 ENST00000579541
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TANC2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TANC2 (see all 270):
    hsa-miR-124* hsa-miR-579 hsa-miR-140-5p hsa-miR-193a-3p hsa-miR-146a hsa-miR-3916 hsa-miR-761 hsa-miR-520b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TANC2
    Predesigned siRNA for gene silencing in human, mouse, rat TANC2
    Clone
    Products:
         
    OriGene clones in human, mouse for TANC2 (see all 5)
    OriGene ORF clones in mouse, rat for TANC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TANC2 (NM_025185)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TANC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TANC2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TANC2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TANC2
      QuantiTect SYBR Green Assays in human, mouse, rat TANC2
      QuantiFast Probe-based Assays in human, mouse, rat TANC2

    Additional mRNA sequence: 

    AB032974.2 AB046856.2 AJ278120.1 BC144357.1 CR936685.1 

    9 DOTS entries:

    DT.97795677  DT.451658  DT.120906648  DT.204808  DT.100740413  DT.120906588  DT.120906599  DT.120906653 
    DT.91890257 

    Selected AceView cDNA sequences (see all 140):

    AK001077 AI433843 BE874850 BX092628 AA394105 BM679720 AK021886 AV729269 
    AL049048 BE220246 AW438758 AI929277 BG114434 AI089848 AU119728 AI690079 
    BF115054 BQ181224 BF439713 BQ021759 AI131156 CR601835 AI815582 AB032974 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TANC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATACAGATT
    TANC2 Expression
    About this image

    TANC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TANC2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.410889
        Custom PCR Arrays for TANC2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TANC2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TANC2
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    QuantiFast Probe-based Assays in human, mouse, rat TANC2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TANC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TANC2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tanc21 , 5 tetratricopeptide repeat, ankyrin repeat and coiled-coil more1, 5 92.09(n)1
    98.04(a)1
      11 (68.73 cM)5
    770971  NM_181071.31  NP_851416.21 
     1055899865 
    chicken
    (Gallus gallus)
    Aves TANC21 tetratricopeptide repeat, ankyrin repeat and coiled-coil more 81.52(n)
    95.03(a)
      419951  XM_004948525.1  XP_004948582.1 
    lizard
    (Anolis carolinensis)
    Reptilia TANC26
    tetratricopeptide repeat, ankyrin repeat and coile...
    89(a)
    1 ↔ 1
    6(61274590-61529073)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ618717.12   -- 77.92(n)    BJ618717.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.89652 Transcribed sequence with moderate similarity to protein more 73.56(n)    57090178 
    fruit fly
    (Drosophila melanogaster)
    Insecta rols6
    rolling pebbles
    29(a)
    1 → many
    3L(12001325-12057959)


    ENSEMBL Gene Tree for TANC2 (if available)
    TreeFam Gene Tree for TANC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TANC2 gene
    ANKS32  ANKRD172  ANKRD292  FEM1A2  ANKHD12  FANK12  KIDINS2202  ANKHD1-EIF4EBP32  
    FEM1B2  TANC12  ANKS62  FEM1C2  
    Selected SIMAP similar genes for TANC2 using alignment to 5 protein entries:     TANC2_HUMAN (see all proteins) (see all similar genes):
    TANC1    RAI14    ANKRD42    ANK2    ANKRD44    KIDINS220
    ANKRD12    DKFZp761E1322    MTPN    ANKRD6    FANK1    ANKRD46
    ANKRD54    ANKS3    CDKN2C    FEM1B    GABPB1    ANK3

    Find genes that share paralogs with TANC2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for TANC2
    PGOHUM00000237043


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TANC2 (see all 7062)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs800119071,2
    C--61084977(+) TAGAG-/AATTAC 1 -- us2k10--------
    rs1425710021,2
    --61085026(+) ATTACG/TTCTCT 1 -- us2k10--------
    rs778222681,2
    C,F--61085190(+) CCCTTC/TCTATG 1 -- us2k13Minor allele frequency- T:0.06CSA WA NA 239
    rs1467919211,2
    --61085215(+) CATGTA/GTATGC 1 -- us2k10--------
    rs359422651,2
    C--61085322(+) TAAAC-/TGAGAGT 1 -- us2k12Minor allele frequency- TG:0.25NA 4
    rs1849840861,2
    C--61085344(+) ATTGGC/TGCCAG 1 -- us2k10--------
    rs792488411,2
    C,F--61085415(+) TGAAAG/ATATCT 1 -- us2k11Minor allele frequency- A:0.13WA 118
    rs1393167781,2
    --61085420(+) GTATCG/TTTCAG 1 -- us2k10--------
    rs1902764581,2
    --61085464(+) TGGGGA/GTCTGG 1 -- us2k10--------
    rs1819636091,2
    --61085465(+) GGGGGC/TCTGGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TANC2 (61086898 - 61336898 bp, first 250kb of TANC2)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TANC2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2657672CNV Deletion23128226
    nsv2116CNV Insertion18451855
    nsv112050CNV Insertion16902084
    nsv457865CNV Loss19166990
    esv27080CNV Loss19812545
    nsv457867CNV Loss19166990
    nsv908681CNV Loss21882294
    nsv908682CNV Loss21882294
    nsv457866CNV Loss19166990
    nsv526079CNV Gain19592680

    Human Gene Mutation Database (HGMD): TANC2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TANC2
    DNA2.0 Custom Variant and Variant Library Synthesis for TANC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615047    OMIM disorders: --


    Find genes that share disorders with TANC2           About GenesLikeMe

    Genetic Association Database (GAD): TANC2

    Export disorders for TANC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TANC2 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with TANC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (DNA Res. 1999)
    4. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    5. Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (J. Proteome Res. 2012)
    6. Diagnostic exome sequencing in persons with severe intellectual disability. (PubMed id 23033978)2 de Ligt J.... Vissers L.E. (N. Engl. J. Med. 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26115 HGNC: 30212 AceView: DKFZP564D166 Ensembl:ENSG00000170921 euGenes: HUgn26115
    ECgene: TANC2 H-InvDB: TANC2

    (According to HUGE)
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    HUGE: KIAA1636 KIAA1148

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TANC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TANC2 gene:
    Search GeneIP for patents involving TANC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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