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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TANC1 Gene

protein-coding   GIFtS: 47
GCID: GC02P159825

tetratricopeptide repeat, ankyrin repeat and coiled-coil...
 Explore 2 diseases affiliated with
TANC1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TANC1    

Aliases
for TANC1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 11 2     TANC2
ROLSB1 2     Protein TANC12
KIAA17281 3     Rolling Pebbles Homolog B2
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Domain-Containing
Protein 12 3
     TPR Domain, Ankyrin-Repeat And Coiled-Coil-Containing2

External Ids:    HGNC: 293641   Entrez Gene: 854612   Ensembl: ENSG000001151837   OMIM: 6113975   UniProtKB: Q9C0D53   

Export aliases for TANC1 gene to outside databases

Previous GC identifers: GC02P159739 GC02P159533 GC02P151714


Summaries
for TANC1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: TANC1_HUMAN, Q9C0D5
Function: May be a scaffold component in the postsynaptic density (By similarity)




Genomic Views
for TANC1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TANC1 gene promoter:
         GCNF   FOXO3   AP-2gamma   FOXO3b   C/EBPalpha   GCNF-1   Sox9   FOXO3a   Cart-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TANC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TANC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TANC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.2   Ensembl cytogenetic band:  2q24.2   HGNC cytogenetic band: 2q24.2

TANC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TANC1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P159825:  view genomic region     (about GC identifiers)

Start:
 159,825,146 bp from pter      End:
 160,089,170 bp from pter
Size:
 264,025 bases      Orientation:
 plus strand

Proteins
for TANC1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TANC1_HUMAN, Q9C0D5 (See protein sequence)
Recommended Name: Protein TANC1  
Size: 1861 amino acids; 202219 Da
Subunit: Interacts probably directly with DLG1, DLG4, HOMER1. Interacts with DLGAP1, INA, CAMK2A, GRIN2B and GRIA1 (By
similarity). Interacts with TNIK. Interacts with MINK1 (By similarity)
Subcellular location: Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity)
Sequence caution: Sequence=AAH37329.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH37329.1; Type=Miscellaneous discrepancy; Note=The cDNA sequence appears to be not correctly spliced at its
3'-end;
Secondary accessions: C9JD88 Q49AI8
Alternative splicing: 2 isoforms:  Q9C0D5-1   Q9C0D5-2   (Incomplete sequence. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TANC1: NX_Q9C0D5

Post-translational modifications:

  • Phosphorylated; by MINK1 and TNIK upon stimulation by RAP2A1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C0D5

    • TANC1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139381.1  NP_203752.2  

    ENSEMBL proteins: 
     ENSP00000263635   ENSP00000396339  

    Human Recombinant Protein Products: 
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    Uscn Proteins for TANC1

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0014069postsynaptic density IEA--
    GO:0030054cell junction IEA--
    GO:0030425dendrite ----
    GO:0043025neuronal cell body IEA--


    TANC1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TANC1

    Protein Domains /
    Families
    for TANC1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TANC1 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR020683 Ankyrin_rpt-contain_dom
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9C0D5

    ProtoNet protein and cluster: Q9C0D5

    UniProtKB/Swiss-Prot: TANC1_HUMAN, Q9C0D5
    Similarity: Belongs to the TANC family
    Similarity: Contains 11 ANK repeats
    Similarity: Contains 3 TPR repeats


    Function
    for TANC1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TANC1_HUMAN, Q9C0D5
    Function: May be a scaffold component in the postsynaptic density (By similarity)

    miRNA
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    hsa-miR-142-5p hsa-miR-562 hsa-miR-548k hsa-miR-199a-3p hsa-miR-106a hsa-miR-29a hsa-miR-301a hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmid: TANC1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for TANC1

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    TANC1 for ontologies           About GeneDecksing


    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tanc1):
     behavior/neurological  nervous system 

    TANC1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TANC1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TANC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/13 Interacting proteins for TANC1 (Q9C0D53 ENSP000002636354) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTBP607093, ENSP000003499604I2D: score=1 STRING: ENSP00000349960
    CASKO149363, ENSP000003674084I2D: score=1 STRING: ENSP00000367408
    DLG1Q129593, ENSP000003457314I2D: score=1 STRING: ENSP00000345731
    DLG4P783523, ENSP000002938134I2D: score=1 STRING: ENSP00000293813
    GRIN2BQ132243, ENSP000002795934I2D: score=1 STRING: ENSP00000279593
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007520myoblast fusion IEA--
    GO:0008542visual learning IEA--
    GO:0097062dendritic spine maintenance IEA--


    TANC1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TANC1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TANC1
    Search CenterWatch for drugs/clinical trials and news about TANC1 

    Transcripts
    for TANC1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TANC1 gene (2 alternative transcripts): 
    NM_001145909.1  NM_033394.2  

    Unigene Cluster for TANC1:

    Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
    Hs.61590  [show with all ESTs]
    Unigene Representative Sequence: BX648238
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263635(uc010zcm.2 uc002uag.3) ENST00000464096(uc002uah.1)
    ENST00000465963 ENST00000470074(uc010fon.3) ENST00000496406 ENST00000454300(uc010fol.1 uc010fom.1)


    miRNA
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    8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate TANC1 (see all 53):
    hsa-miR-142-5p hsa-miR-562 hsa-miR-548k hsa-miR-199a-3p hsa-miR-106a hsa-miR-29a hsa-miR-301a hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmid: TANC1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TANC1 (see all 7)
    OriGene shRNA RFP: TANC1
    OriGene siRNA: TANC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TANC1
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): TANC1 (NM_001145909)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TANC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TANC1

    Additional cDNA sequence: 

    AB051515.1 AK000401.1 AK023422.1 AK094285.1 AK123161.1 AK128859.1 AK308899.1 AL833258.1 
    BC037329.1 BC150597.1 BX648238.1 BX648327.1 

    11 DOTS entries:

    DT.113986  DT.75105544  DT.40309268  DT.95349560  DT.75102900  DT.40188880  DT.91880496  DT.92432227 
    DT.100647930  DT.100703749  DT.439489 

    24/164 AceView cDNA sequences (see all 164):

    AI080379 Z44594 AA630087 CA394398 AA700643 AA774703 BM970999 AW780332 
    BX280598 BQ008657 AW029363 AI745307 AK128859 AA773835 BE349247 BU733750 
    AW188092 BF435307 AI246536 AI554932 BM702655 AL710160 AK123161 BX643568 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TANC1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21a ·
    SP1:                    -     -                                                                                                           -                 -   
    SP2:                    -     -           -     -     -     -     -     -     -     -     -     -     -     -                             -                 -   
    SP3:                                                                                                                                                        -   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21b · 21c ^ 22 ^ 23
    SP1:        -               
    SP2:        -               
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for TANC1

    Expression
    for TANC1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TANC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGTTTTGCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TANC1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TANC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TANC1

    SOURCE GeneReport for Unigene cluster: Hs.61590
        SABiosciences Custom PCR Arrays for TANC1
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TANC1

    Orthologs
    for TANC1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for TANC1 gene from 7/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TANC11 tetratricopeptide repeat, ankyrin repeat and coiled-coil more 71.1(n)
    73.9(a)    		   424330  XM_422174.3  XP_422174.3 
    lizard
    (Anolis carolinensis)    		 Reptilia TANC16
    --
    		 --
    		 78(a)
    11(a)
    		 1 ↔ 1
    possible ortholog
    		 GL343379.1(249650-332426)
    4(101979115-101980806)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1003346501 protein TANC1-like 66.37(n)
    68.51(a)    		   100334650  XM_003199255.1  XP_003199303.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta nompC6
    rols6
    (see all 3)    		 rolling pebbles
    (see all 3)    		 6(a)
    27(a)
    (see all 3)    		 possible ortholog
    1 ↔ many
    (see all 3)    		 2L(5342321-5365760)
    3L(12001325-12057959)
    worm
    (Caenorhabditis elegans)    		 Secernentea tag-1446
    mlt-46
    		 MoLTing defective family member (mlt-4)
    		 6(a)
    11(a)
    		 possible ortholog
    possible ortholog
    		 IV(11038634-11047401)
    V(20281360-20289386)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 ankyrin repeat domain-containing protein 50, putat...
    		 15(a)
    		 possible ortholog
    		 3(25568429-25570099)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria yahD6
    		 ankyrin repeat protein
    		 14(a)
    		 possible ortholog
    		 Chromosome(334504-335109)


    ENSEMBL Gene Tree for TANC1 (if available)
    TreeFam Gene Tree for TANC1 (if available) 

    Paralogs
    for TANC1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TANC1 gene
    TANC22  TNKS22  ANKRD172  ANK32  ANKHD12  ANK12  ANKRD522  ANKHD1-EIF4EBP32  
    TNKS2  ANKRD502  INVS2  ANKRD282  ANK22  ANKRD442  
    5 SIMAP similar genes for TANC1 using alignment to 2 protein entries:     TANC1_HUMAN (see all proteins):
    TANC2    DKFZp761E1322    MTPN    ANKRD29    CDKN2C

    TANC1 for paralogs           About GeneDecksing



    Genomic Variants
    for TANC1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4577 NCBI SNPs in TANC1 are shown (see all 4577)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1849553541,2
    		--159823157(+) AGTTAC/TTTCTT 2 -- us2k10--------
    rs1409233311,2
    		--159823270(+) CTACTG/TAAGGA 2 -- us2k10--------
    rs739668021,2
    		C,--159823341(+) TTCATC/AAAAAA 2 -- us2k12Minor allele frequency- A:0.04WA 120
    rs1896214621,2
    		--159823384(+) GAAAAA/GTGTGG 2 -- us2k10--------
    rs1819158851,2
    		--159823598(+) GATTTC/TGTTTC 2 -- us2k10--------
    rs587692591,2
    		--159823630(+) TACCAT/CATTTT 2 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1502235731,2
    		--159823858(+) TGTGTA/GGCATT 2 -- us2k10--------
    rs8420751,2
    		C,F,A,H,--159823927(-) CCCTAT/CATAAA 2 -- us2k126Minor allele frequency- C:0.31NA EA MN NS WA 3030
    rs1871124671,2
    		--159823937(+) GAAGCG/TCTGCG 2 -- us2k10--------
    rs348421971,2
    		C,--159824096(+) CACAA-/TTTCCC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TANC1 (159825146 - 160075146 bp, first 250kb of TANC1)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 14 variations for TANC1
         12 CNVs: 23586 58928 90096 78839 90099 78837 63222 78836 90098 53156 90097 78838
         2 Indels: 11159 90100

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    Disorders / Diseases
    for TANC1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TANC1 for disorders           About GeneDecksing

    OMIM gene information: 611397    OMIM disorders: --

    2 diseases for TANC1:    About MalaCards
    choroiditis    neuronitis


    Export disorders for TANC1 gene to outside databases

    Publications
    for TANC1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TANC1 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TANC1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins. (PubMed id 15673434)1, 3 Suzuki T....Endo S. (2005)
    2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
    3. GWAS for discovery and replication of genetic loci as sociated with sudden cardiac arrest in patients with coronary artery disease. (PubMed id 21658281)1 Aouizerat B.E....Tseng Z.H. (2011)
    4. Complex chromosomal rearrangement in a girl with psyc homotor-retardation and a de novo inversion: inv(2)(p15;q24.2). (PubMed id 21739571)1 Granot-Hershkovitz E....Abeliovich D. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    7. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
    8. MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1. (PubMed id 18930710)2 Nonaka H....Kariya K. (2008)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    External Searches for TANC1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TANC1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 85461 HGNC: 29364 AceView: TANC Ensembl:ENSG00000115183 euGenes: HUgn85461
    ECgene: TANC1 H-InvDB: TANC1

    Other Databases showing TANC1 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1728

    Specialized Databases showing TANC1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TANC1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TANC1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TANC1 gene:
    Search GeneIP for patents involving TANC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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