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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAL2 Gene

protein-coding   GIFtS: 50
GCID: GC09P108424

T-cell acute lymphocytic leukemia 2
 Explore 9 diseases affiliated with
TAL2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TAL2    

Aliases
for TAL2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
T-Cell Acute Lymphocytic Leukemia 21 2
BHLHa191
Class A Basic Helix-Loop-Helix Protein 192 3
TAL-22 3
T-Cell Acute Lymphocytic Leukemia Protein 22
BHLHA193

External Ids:    HGNC: 115571   Entrez Gene: 68872   Ensembl: ENSG000001860517   OMIM: 1868555   UniProtKB: Q165593   

Export aliases for TAL2 gene to outside databases

Previous GC identifers: GC09P099225 GC09P100168 GC09P101882 GC09P103804 GC09P105504 GC09P107464 GC09P078026


Summaries
for TAL2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TAL2:
This intronless gene encodes a helix-loop-helix protein. Translocations between this gene on chromosome 9 and the
T-cell receptor beta-chain locus on chromosome 7 have been associated with activation of the T-cell acute lymphocytic
leukemia 2 gene and T-cell acute lymphoblastic leukemia. (provided by RefSeq, Mar 2009)

Gene Wiki entry for TAL2


Genomic Views
for TAL2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAL2 gene promoter:
         Bach2   NF-AT   RORalpha1   NF-AT4   POU2F1   NF-AT2   POU2F1a   NF-AT3   FOXO1   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TAL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TAL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q32   Ensembl cytogenetic band:  9q31.2   HGNC cytogenetic band: 9q32

TAL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAL2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P108424:  view genomic region     (about GC identifiers)

Start:
 108,424,738 bp from pter      End:
 108,425,393 bp from pter
Size:
 656 bases      Orientation:
 plus strand

Proteins
for TAL2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TAL2_HUMAN, Q16559 (See protein sequence)
Recommended Name: T-cell acute lymphocytic leukemia protein 2  
Size: 108 amino acids; 12291 Da
Secondary accessions: A0AVI7

Explore the universe of human proteins at neXtProt for TAL2: NX_Q16559

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16559

    • TAL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005412.1  
    ENSEMBL proteins: 
     ENSP00000334547  

    Human Recombinant Protein Products: 
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    Uscn Proteins for TAL2


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    Uscn ELISAs and CLIAs for TAL2

    Protein Domains /
    Families
    for TAL2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TAL2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR011598 HLH_dom

    Graphical View of Domain Structure for InterPro Entry Q16559

    ProtoNet protein and cluster: Q16559

    1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH

    UniProtKB/Swiss-Prot: TAL2_HUMAN, Q16559
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


    Function
    for TAL2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for TAL2:
    helix loop helix protein,homologous to TAL1,involved in T cell acute lymphoblastic leukemia,with translocation
    t(7;9)(q35;q34)

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAL2 

    Cell Line
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    Search LifeMap BioReagents cell lines for TAL2

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046983protein dimerization activity IEA--


    TAL2 for ontologies           About GeneDecksing


    Animal Models:
         6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tal2):
     behavior/neurological  growth/size  hematopoietic system  homeostasis/metabolism  mortality/aging 
     nervous system 

    TAL2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TAL2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TAL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/11 Interacting proteins for TAL2 (Q165593 ENSP000003345474) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LMO1P258003, ENSP000003382074I2D: score=3 STRING: ENSP00000338207
    LMO2P257913, ENSP000002578184I2D: score=2 STRING: ENSP00000257818
    TCF12Q990813, ENSP000003310574I2D: score=1 STRING: ENSP00000331057
    MAPK3P273613, ENSP000002630254I2D: score=1 STRING: ENSP00000263025
    TCF3P159233, ENSP000002629654I2D: score=1 STRING: ENSP00000262965
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007610behavior IEA--
    GO:0009791post-embryonic development IEA--
    GO:0021794thalamus development IEA--


    TAL2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TAL2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAL2
    Search CenterWatch for drugs/clinical trials and news about TAL2 

    Transcripts
    for TAL2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TAL2 gene: 
    NM_005421.2  

    Unigene Cluster for TAL2:

    T-cell acute lymphocytic leukemia 2
    Hs.247978  [show with all ESTs]
    Unigene Representative Sequence: NM_005421
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000334077(uc004bct.3)

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAL2 (see all 7)
    OriGene shRNA RFP: TAL2
    OriGene siRNA: TAL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAL2
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAL2

    Additional cDNA sequence: 

    BC069422.1 BC126373.1 BC126375.1 

    1 DOTS entry:

    DT.425314 

    4 AceView cDNA sequences:

    NM_005421 BC069422 AA904907 AA767775 

    GeneLoc Exon Structure


    Expression
    for TAL2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGAATGTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TAL2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeForegutForegut Endoderm CellsEndoderm
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TAL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TAL2

    SOURCE GeneReport for Unigene cluster: Hs.247978
        SABiosciences Custom PCR Arrays for TAL2
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAL2

    Orthologs
    for TAL2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TAL2 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TAL21 T-cell acute lymphocytic leukemia 2 76.01(n)
    76.64(a)    		   427304  XM_424886.3  XP_424886.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TAL26
    		 --
    		 78(a)
    		 1 ↔ 1
    		 GL343218.1(1314318-1314641)
    zebrafish
    (Danio rerio)    		 Actinopterygii tal21 T-cell acute lymphocytic leukemia 2 60.78(n)
    61.76(a)    		   394239  NM_201339.2  NP_958496.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta HLH3B6
    		 Helix loop helix protein 3B
    		 12(a)
    		 1 → many
    		 X(2574232-2575756)


    ENSEMBL Gene Tree for TAL2 (if available)
    TreeFam Gene Tree for TAL2 (if available) 

    Paralogs
    for TAL2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TAL2 gene
    TCF242  NHLH12  TWIST12  TWIST22  TAL12  HAND22  TCF232  LYL12  
    NHLH22  TCF152  SCXB2  TCF212  HAND12  MSC2  SCXA2  
    18/23 SIMAP similar genes for TAL2 using alignment to 1 protein entry:     TAL2_HUMAN(see all similar genes):
    SCL    TAL1    tal-1    TWIST2    ATOH7    NHLH1
    NHLH2    SCXA    SCXB    TWIST1    ATOH1    LYL1
    HAND2    NEUROD2    NEUROD6    ASCL3    PTF1A    TCF15

    TAL2 for paralogs           About GeneDecksing



    Genomic Variants
    for TAL2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/80 NCBI SNPs in TAL2 are shown (see all 80)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1824514451,2
    		--108422808(+) TCTGAC/TTACAG 1 -- us2k10--------
    rs6525741,2
    		C,A,--108422826(+) CCACCA/GCGCCC 1 -- us2k12Minor allele frequency- G:0.25NA 4
    rs1496555041,2
    		--108422870(+) TTCACC/TGTGTT 1 -- us2k10--------
    rs1400885371,2
    		--108422916(+) TCTGC-/CACCCCC 1 -- us2k10--------
    rs70411881,2
    		C,F,A--108422917(+) CTGCCG/ACCCCC 1 -- us2k1 tfbs33Minor allele frequency- A:0.50NA WA 6
    rs713660081,2
    		C--108422918(-) AAGTC-/GGGGGGG 1 -- us2k11Minor allele frequency- GG:0.00NA 2
    rs2010576901,2
    		--108422929(+) CCCCC-/CCCG  
                ACTTG     		1 -- us2k10--------
    rs108162911,2
    		C,A,--108422932(+) CCCCCA/C/GACTTG 1 -- us2k13WA EA 240
    rs1149126571,2
    		F,--108423003(+) TTATTG/CAGCCT 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs586124541,2
    		C,--108423116(+) TTGAAA/TCACAG 1 -- us2k14Minor allele frequency- T:0.16WA CSA 122

    HapMap Linkage Disequilibrium report for TAL2 (108424738 - 108425393 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TAL2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAL2
    DNA2.0 Custom Variant and Variant Library Synthesis for TAL2

    Disorders / Diseases
    for TAL2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TAL2 for disorders           About GeneDecksing

    OMIM gene information: 186855    OMIM disorders: --

    UniProtKB/Swiss-Prot: TAL2_HUMAN, Q16559
  • Note=A chromosomal aberration involving TAL2 may be a cause of some T-cell acute lymphoblastic leukemia
    • (T-ALL). Translocation t(7;9)(q34;q32) with TCRB

    9 diseases for TAL2:    About MalaCards
    acute lymphocytic leukemia    lymphocytic leukemia    acute lymphoblastic leukemia    leukemia
    lymphoblastic leukemia    leukemia-2, t-cell acute lymphoblastic    stem cell leukemia    t-cell leukemia
    ovarian cancer

    Genatlas disease: TAL2
    acute lymphoblastic leukemia (T cell) with breakpoint in t(7;9)(q35;q34) translocation

    Tumor Gene Database (TGDB): TAL2

    Export disorders for TAL2 gene to outside databases

    Publications
    for TAL2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAL2 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TAL2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. (PubMed id 1763056)1, 2, 3, 9 Xia Y.... Baer R.J. (1991)
    2. Products of the TAL2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity. (PubMed id 8152805)1, 2, 9 Xia Y.... Baer R. (1994)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. Correlations among ERCC1, XPB, UBE2I, EGF, TAL2 and I LF3 revealed by gene signatures of histological subtypes of patients with epith elial ovarian cancer. (PubMed id 21971700)1 Guo Y....Yu J.J. (2012)
    6. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    7. Common genetic variation and performance on standardi zed cognitive tests. (PubMed id 20125193)1 Cirulli E.T....Goldstein D.B. (2010)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    9. Meta-analysis of genome-wide association data identif ies two loci influencing age at menarche. (PubMed id 19448620)1 Perry J.R....Murabito J.M. (2009)
    10. Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL. (PubMed id 12567187)1 Marculescu R....Nadel B. (2003)

    External Searches for TAL2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TAL2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6887 HGNC: 11557 AceView: TAL2 Ensembl:ENSG00000186051 euGenes: HUgn6887
    ECgene: TAL2 H-InvDB: TAL2

    Other Databases showing TAL2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TAL2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAL2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TAL2 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for TAL2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TAL2 gene:
    Search GeneIP for patents involving TAL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    In Situ Hybridization Assays from
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    About This Section

     
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