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TAGLN3 Gene

protein-coding   GIFtS: 53
GCID: GC03P111717

Transgelin 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transgelin 31 2     NP252 3
NP222 3 5     NP242 5
Neuronal Protein 222 3     transgelin-32
Neuronal Protein NP252 3     

External Ids:    HGNC: 298681   Entrez Gene: 291142   Ensembl: ENSG000001448347   OMIM: 6079535   UniProtKB: Q9UI153   

Export aliases for TAGLN3 gene to outside databases

Previous GC identifers: GC03P113201 GC03P109092


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TAGLN3 Gene:
TAGLN3 (transgelin 3) is a protein-coding gene. An important paralog of this gene is TAGLN2.

Gene Wiki entry for TAGLN3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TAGLN3 gene promoter:
         GR   AP-1   GR-alpha   STAT5A   Ik-3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAGLN3 promoter sequence
   Search Chromatin IP Primers for TAGLN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAGLN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.2   Ensembl cytogenetic band:  3q13.2   HGNC cytogenetic band: 3q13.2

TAGLN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAGLN3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P111717:  view genomic region     (about GC identifiers)

Start:
111,717,511 bp from pter      End:
111,732,735 bp from pter
Size:
15,225 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TAGL3_HUMAN, Q9UI15 (See protein sequence)
Recommended Name: Transgelin-3  
Size: 199 amino acids; 22473 Da
Sequence caution: Sequence=AAF17189.1; Type=Frameshift; Positions=199;
Secondary accessions: D3DN64 Q96A74

Explore the universe of human proteins at neXtProt for TAGLN3: NX_Q9UI15

Explore proteomics data for TAGLN3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TAGLN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001008273.1  NP_001008274.1  NP_037391.2  

    ENSEMBL proteins: 
     ENSP00000419105   ENSP00000273368   ENSP00000391160   ENSP00000420675   ENSP00000417904  
     ENSP00000420346   ENSP00000377494  

    TAGLN3 Human Recombinant Protein Products:

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    Novus Biologicals TAGLN3 Proteins
    Novus Biologicals TAGLN3 Lysates
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    ProSpec Recombinant Protein for TAGLN3
    Cloud-Clone Corp. Proteins for TAGLN3

     
    Search eBioscience for Proteins for TAGLN3 

     
    antibodies-online proteins for TAGLN3 (9 products) 

     
    antibodies-online peptides for TAGLN3

    TAGLN3 Antibody Products:

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    antibodies-online antibodies for TAGLN3 (36 products) 

    TAGLN3 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TAGLN3
    Cloud-Clone Corp. CLIAs for TAGLN3
    Search eBioscience for ELISAs for TAGLN3 
    antibodies-online kits for TAGLN3 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR001061 TAGLN
     IPR001715 CH-domain
     IPR003096 SM22_calponin
     IPR000557 Calponin_repeat

    Graphical View of Domain Structure for InterPro Entry Q9UI15

    ProtoNet protein and cluster: Q9UI15

    3 Blocks protein domains:
    IPB001061 Smooth muscle protein 22-alpha (transgelin) signature
    IPB001715 Calponin-like actin-binding
    IPB003247 Calponin-like actin-binding subtype


    UniProtKB/Swiss-Prot: TAGL3_HUMAN, Q9UI15
    Similarity: Belongs to the calponin family
    Similarity: Contains 1 calponin-like repeat
    Similarity: Contains 1 CH (calponin-homology) domain


    Find genes that share domains with TAGLN3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TAGLN3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for TAGLN3:
     Increased HPV18 LCR reporter a  Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TAGLN3

    miRNA
    Products:
        
    miRTarBase miRNAs that target TAGLN3:
    hsa-mir-26b-5p (MIRT030107)

    Block miRNA regulation of human, mouse, rat TAGLN3 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TAGLN3:
    hsa-miR-153 hsa-miR-182 hsa-miR-448 hsa-miR-3168 hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidTAGLN3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TAGLN3
    Predesigned siRNA for gene silencing in human, mouse, rat TAGLN3

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for TAGLN3

    Clone
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    OriGene clones in human, mouse for TAGLN3 (see all 18)
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    GenScript: all cDNA clones in your preferred vector (see all 3): TAGLN3 (NM_001008272)
    Sino Biological Human cDNA Clone for TAGLN3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAGLN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAGLN3

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TAGLN3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAGLN3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with TAGLN3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAGLN3
    Interactions:

        Search GeneGlobe Interaction Network for TAGLN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TAGLN3 (Q9UI153 ENSP000002733684) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CRYABP025113, ENSP000002272514I2D: score=1 STRING: ENSP00000227251
    SARS2Q9NP813I2D: score=5 
    SLC25A37Q9NYZ23I2D: score=5 
    DLG4P783523I2D: score=1 
    TXNL4AENSP000002696014STRING: ENSP00000269601
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0007417central nervous system development TAS8015377
    GO:0007517muscle organ development ----

    Find genes that share ontologies with TAGLN3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TAGLN3 (TAGL3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TAGLN3 gene (3 alternative transcripts): 
    NM_001008272.1  NM_001008273.1  NM_013259.2  

    Unigene Cluster for TAGLN3:

    Transgelin 3
    Hs.169330  [show with all ESTs]
    Unigene Representative Sequence: NM_013259
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000478951 ENST00000273368 ENST00000455401(uc003dyo.3) ENST00000494932
    ENST00000486460 ENST00000469385 ENST00000393917(uc003dym.3 uc003dyl.3 uc003dyn.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat TAGLN3 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TAGLN3:
    hsa-miR-153 hsa-miR-182 hsa-miR-448 hsa-miR-3168 hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidTAGLN3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TAGLN3
    Predesigned siRNA for gene silencing in human, mouse, rat TAGLN3
    Clone
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    OriGene clones in human, mouse for TAGLN3 (see all 18)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TAGLN3 (NM_001008272)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAGLN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAGLN3
    Primer
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    OriGene qPCR primer pairs and template standards for TAGLN3
    OriGene qSTAR qPCR primer pairs in human, mouse for TAGLN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TAGLN3
      QuantiTect SYBR Green Assays in human, mouse, rat TAGLN3
      QuantiFast Probe-based Assays in human, mouse, rat TAGLN3

    Additional mRNA sequence: 

    AF087855.1 AF112201.1 AF303058.1 AK315289.1 BC015329.1 BT007408.1 

    7 DOTS entries:

    DT.101981687  DT.92447519  DT.92447508  DT.100779058  DT.120900008  DT.40119930  DT.92447509 

    Selected AceView cDNA sequences (see all 132):

    BM857481 BM894501 CR591700 BQ549712 AI801870 AA322467 BM704283 BQ719637 
    BU728809 BC015329 BT007408 BM894229 AW205010 AA973428 BF346837 AW298406 
    BM669668 R54518 CR600116 H22053 BQ549231 BM547950 AL712675 AF303058 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TAGLN3    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b
    SP1:                    -     -                                       
    SP2:                    -     -     -                                 
    SP3:                    -                                             
    SP4:                                                                  


    ECgene alternative splicing isoforms for TAGLN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAGLN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTCTACGA
    TAGLN3 Expression
    About this image


    TAGLN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 13 entries
             Endothelial Cells Blood Brain Barrier
             Thalamus
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Epithelial Cells
             Fetal Matrix Cells Hair Follicle
     
     NULL (Uncategorized)
             Neural rosettes
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer
    TAGLN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TAGLN3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.169330

    UniProtKB/Swiss-Prot: TAGL3_HUMAN, Q9UI15
    Tissue specificity: Widely expressed in the brain. Expression is increased in the superior frontal cortex of
    alcoholics, but not in the motor cortex or cerebellum

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAGLN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TAGLN3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tagln31 , 5 transgelin 31, 5 93.63(n)1
    99.5(a)1
      16 (29.99 cM)5
    563701  NM_019754.31  NP_062728.11 
     457112305 
    chicken
    (Gallus gallus)
    Aves TAGLN31 transgelin 3 80.74(n)
    88.44(a)
      418420  XM_416634.4  XP_416634.1 
    lizard
    (Anolis carolinensis)
    Reptilia TAGLN36
    transgelin 3
    87(a)
    1 ↔ 1
    3(167697308-167721274)
    zebrafish
    (Danio rerio)
    Actinopterygii wufc80d072 wufc80d07 77.73(n)   325474  BC062382.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Chd646
    Chd64
    44(a)
    many ↔ many
    3L(4114289-4122388)
    worm
    (Caenorhabditis elegans)
    Secernentea cpn-21 cpn-2 46.05(n)
    42.27(a)
      173424  NM_061312.3  NP_493713.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SCP16
    Component of yeast cortical actin cytoskeleton, bi...
    28(a)
    1 → many
    XV(1026007-1026609) YOR367W


    ENSEMBL Gene Tree for TAGLN3 (if available)
    TreeFam Gene Tree for TAGLN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TAGLN3 gene
    TAGLN22  TAGLN2  CNN12  CNN32  CNN22  
    5 SIMAP similar genes for TAGLN3 using alignment to 4 protein entries:     TAGL3_HUMAN (see all proteins):
    TAGLN2    TAGLN    CNN3    CNN2    CNN1

    Find genes that share paralogs with TAGLN3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TAGLN3 (see all 421)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs612120241,2
    C--111691333(+) AAACA-/GAAGGTG 3 -- int10--------
    rs76277441,2
    C,F,A,H--111715635(+) ATTGCG/ACCCCA 2 -- us2k18Minor allele frequency- A:0.34WA NA CSA EA 368
    rs113568871,2
    C--111715669(+) GAATC-/AAAAAA 2 -- us2k1 trp31Minor allele frequency- A:0.50CSA 2
    rs1166717981,2
    F--111715700(+) AAAACA/GTTAAC 2 -- us2k11Minor allele frequency- G:0.01WA 118
    rs779819341,2
    C--111715760(+) TGTCAC/ACCCTG 2 -- us2k13Minor allele frequency- A:0.03CSA NA EA 242
    rs1894769101,2
    --111715811(+) TTCTGA/GACACT 2 -- us2k10--------
    rs1819576001,2
    --111715885(+) ATTCAA/CTTAAA 2 -- us2k10--------
    rs1407196351,2
    --111715904(+) GCTACG/TCTGTT 2 -- us2k10--------
    rs1142541091,2
    C,F--111715994(+) GAATTG/CTTTCA 2 -- us2k11Minor allele frequency- C:0.08WA 118
    rs1501024851,2
    --111716044(+) CCAGCC/TATGGA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for TAGLN3 (111717511 - 111732735 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TAGLN3: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TAGLN3
    DNA2.0 Custom Variant and Variant Library Synthesis for TAGLN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607953    OMIM disorders: --


    Find genes that share disorders with TAGLN3           About GenesLikeMe


    Export disorders for TAGLN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TAGLN3 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TAGLN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain. (PubMed id 11238712)1, 2, 3, 9 Fan L.... Wilce P.A. (J. Neurochem. 2001)
    2. The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations. (PubMed id 8015377)1, 3, 9 Ren W.Z....Liew C.C. (Brain Res. Mol. Brain Res. 1994)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    5. Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia. (PubMed id 15781144)1, 9 Ito M....Matsumoto I. (Neurosci. Lett. 2005)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Expression of hNP22 is altered in the frontal cortex and hippocampus of the alcoholic human brain. (PubMed id 14506410)1 Depaz I....Wilce P.A. (Alcohol. Clin. Exp. Res. 2003)
    10. Expressed sequence tag analysis of human retina for the NEIBank project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. (PubMed id 12107411)1 Wistow G.... Peterson K. (Mol. Vis. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29114 HGNC: 29868 AceView: NP25 Ensembl:ENSG00000144834 euGenes: HUgn29114
    ECgene: TAGLN3 H-InvDB: TAGLN3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TAGLN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TAGLN3 gene:
    Search GeneIP for patents involving TAGLN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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