Aliases for TAGLN Gene
External Ids for TAGLN Gene
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TAGLN Gene
TAGLN (Transgelin) is a Protein Coding gene. GO annotations related to this gene include actin binding. An important paralog of this gene is CNN3.
UniProtKB/Swiss-Prot for TAGLN Gene
Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.