Services
Jump to Section...
Aliases for TAGAP
Databases for TAGAP
Disorders for TAGAP
Domains/Families for TAGAP
Drugs/Compounds for TAGAP
Expression for TAGAP
Function for TAGAP
Location for TAGAP
Medical News for TAGAP
Orthologs for TAGAP
Paralogs for TAGAP
Pathways/Interactions for TAGAP
Proteins for TAGAP
Publications for TAGAP
SNPs for TAGAP
Search Box for TAGAP
Services for TAGAP
Summaries for TAGAP
Technologies for TAGAP
Transcripts for TAGAP
TOP
BOTTOM
Aliases & Descriptions for TAGAP
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Aliases FKSG15 2 FLJ32631 1 , 2 FLJ39771 2 MGC133247 2 MGC27381 2 OTTHUMP00000017514 2 OTTHUMP00000017515 2 OTTHUMP00000017516 2 TAGAP1 2 , 3
Descriptions T-cell activation GTPase activating protein 1 T-cell activation GTPase-activating protein 3 T-cell activation Rho GTPase-activating protein 2 T-cell activation RhoGTPase activating protein 2
Search outside databases for aliases for TAGAP genePrevious GC identifers: GC06M158897 GC06M159329 GC06M159365 GC06M159426
Summaries for TAGAP (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
EntrezGene summary for TAGAP : This gene encodes a protein that may function as a Rho GTPase-activating protein. Transcriptvariants encoding distinct isoforms have been identified. [provided by RefSeq] UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103 Function : May function as a GTPase-activating protein and may play important roles during T-cellactivation
Genomic Location for TAGAP
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the TAGAP gene Entrez Gene cytogenetic band: 6q25.3 Ensembl cytogenetic band: 6q25.3 HGNC cytogenetic band: 6q25.3 TAGAP Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure
GeneLoc location for GC06M159375:
(about GC identifiers )
Start:
159,376,012 bp from pter
End:
159,386,172 bp from pter
Size:
10,161 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000006.10 NT_007422.13 Proteins for TAGAP
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103 (See
protein sequence )Recommended Name: T-cell activation Rho GTPase-activating protein Size : 731 amino acids; 80703 Da
Secondary accessions : Q2NKM8 Q8NI40 Q96KZ2 Q96QA2Alternative splicing : 4 isoforms : Q8N103-1 Q8N103-2 Q8N103-3 Q8N103-4
REFSEQ proteins (3 alternative transcripts):
NP_473455.2 NP_620165.1 NP_687034.1 ENSEMBL proteins: ENSP00000356033 ENSP00000356028 ENSP00000322650 ENSP00000340217 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 1 Gene Ontology (GO) cellular component term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005622 intracellular
IEA --
About this table Antibodies for TAGAP: Assays for TAGAP:
Protein
Domains/ Families for TAGAP(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Graphical View of Domain Structure for InterPro Entry Q8N103 ProtoNet protein and cluster: Q8N103
1 Blocks protein family : IPB000198 RhoGAP domain UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103 Similarity : Contains 1 Rho-GAP domain
Gene Function for TAGAP
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_152133 Applied Biosystems Silencer ® siRNAs for TAGAP Sigma-Aldrich siRNA for TAGAP Sigma-Aldrich shRNA for TAGAP Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_054114                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_054114                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_054114  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_054114 UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103 Function : May function as a GTPase-activating protein and may play important roles during T-cellactivation
1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005085 guanyl-nucleotide exchange factor activity
IEA --
About this table
Pathways & Interactions for TAGAP
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
5/68 Interacting proteins for TAGAP (ENSP00000356033 3 ) via UniProtKB, MINT, and/or STRING (see all 68
)About this table 1 Gene Ontology (GO) biological process term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0007165 signal transduction
IEA --
About this table
Drugs & Compounds for TAGAP (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Browse Tocris compounds for TAGAP
Transcripts for TAGAP(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
OriGene , Expression Assays from Applied Biosystems )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3 ): NM_152133 Sigma-Aldrich siRNA for TAGAP Sigma-Aldrich shRNA for TAGAP Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_054114 NM_138810 NM_152133
REFSEQ mRNAs for TAGAP gene (3 alternative transcripts): NM_054114.3 NM_138810.2 NM_152133.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_054114 NM_138810 NM_152133
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_054114                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_054114                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_054114  
Additional cDNA sequence: AF385429.1 AF385430.1 AK057193.1 AK097090.1 AK298686.1 AL832662.1 BC015859.1 BC111731.1
8 DOTS entries : DT.40312762 DT.40308071 DT.40125502 DT.100673318 DT.100776153 DT.100642280 DT.101979617 DT.97772033
24/56 AceView cDNA sequences (see all 56
):AK097090 NM_054114 AF385429 AK057193 BF591040 NM_138810 AA352840 AI253155 BM991735 BX489278 AF385430 AW576600 BE676780 BX342972 AI349366 AA251806 AW008517 AI766650 NM_152133 AI356482 AI760827 BF928548 CA306993 AW407984
highest scoring ESTs for TAGAP :AF385429 AF385430 AI760827 AK097090 AL832662 AW408019 AW502767 BC015859 BG536356 CA407943
Unigene Cluster for TAGAP: T-cell activation RhoGTPase activating protein Hs.529984 [show with all ESTs ] Unigene Representative Sequence: NM_054114 GeneLoc Exon Structure 5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TAGAP (see all 9
) ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11 SP1 :               -   -   -           -           -       SP2 :               -   -   -   -   -       -           -       SP3 :               -   -   -           -                 SP4 :               -   -             -                 SP5 :               -   -   -                          
About this scheme ECgene alternative splicing isoforms for TAGAP 4 Ensembl transcripts including schematic representations : ENST00000367066
ENST00000367061
ENST00000326965
ENST00000338313
Expression for TAGAP
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
TAGAP expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for TAGAP 1 / 2 / 3
7 probe-sets matching TAGAP gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: ATATCCTATCSOURCE GeneReport for Unigene cluster: Hs.529984
Orthologs for TAGAP
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Orthologs for TAGAP gene from 5/7 species (see all 7
)
About this table Species with no ortholog for TAGAP ENSEMBL Gene Tree for TAGAP Paralogs for TAGAP (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Paralogs for TAGAP gene ARHGAP20 2
SNPs/Variants for TAGAP (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
HapMap Linkage Disequilibrium images for TAGAP (up to first 250kb)
Disorders & Mutations for TAGAP
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
OMIM: 609667 Human Genome Epidemiology Navigator: TAGAP (4 documents)
Medical News for TAGAP (Possibly Related Articles in
Doctor's Guide )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Publications for TAGAP (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
10/11 PubMed articles for TAGAP gene (see all 11
): Newly identified genetic risk variants for celiac disease related to the immune response. (PubMed id 18311140) 2, 3 Hunt K.A....van Heel D.A. (2008) Identification of dysregulated genes in lymphocytes from children with Down syndrome. (PubMed id 18356936) 2, 3 Sommer C.A....Henrique-Silva F. (2008) Induction of RhoGAP and pathological changes characteristic of Alzheimer's disease by UAHFEMF discharge in rat brain. (PubMed id 16375659) 2, 3 Chang I.F. and Hsiao H.Y. (2005) T lymphocyte activation gene identification by coregulated expression on DNA microarrays. (PubMed id 15177553) 3, 4 Mao M.... Linsley P.S. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 3, 4 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 3, 4 Ota T....Sugano S. (2004) The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404) 3, 4 Mungall A.J.... Beck S. (2003) Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061) 3 Trynka G....Wijmenga C. (2009) Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease. (PubMed id 18805825) 3 Romanos J....Wijmenga C. (2009) Shared and distinct genetic variants in type 1 diabetes and celiac disease. (PubMed id 19073967) 3 Smyth D.J....Todd J.A. (2008)
Search for TAGAP
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Genome Databases showing TAGAP
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Other Databases showing TAGAP
(According to HUGE )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
--
Specialized Databases showing TAGAP (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
-- Services for TAGAP (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Location
Medical News
Orthologs
Paralogs
Pathways/Interactions
Proteins
Publications
SNPs
Search Box
Services
Summaries
Technologies
Transcripts
TOP
BOTTOM
Products for TAGAP:
Search Tocris compounds for TAGAP
Jump to Section...
Aliases for TAGAP
Databases for TAGAP
Disorders for TAGAP
Domains/Families for TAGAP
Drugs/Compounds for TAGAP
Expression for TAGAP
Function for TAGAP
Location for TAGAP
Medical News for TAGAP
Orthologs for TAGAP
Paralogs for TAGAP
Pathways/Interactions for TAGAP
Proteins for TAGAP
Publications for TAGAP
SNPs for TAGAP
Search Box for TAGAP
Services for TAGAP
Summaries for TAGAP
Technologies for TAGAP
Transcripts for TAGAP
TOP
BOTTOM
GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009