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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAGAP Gene

protein-coding   GIFtS: 53
GCID: GC06M159457

T-Cell Activation RhoGTPase Activating Protein

(Previous name: T-cell activation GTPase activating protein)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
T-Cell Activation RhoGTPase Activating Protein1 2     IDDM212
TAGAP12 3     T-Cell Activation Rho GTPase-Activating Protein2
T-Cell Activation GTPase Activating Protein1     T-Cell Activation GTPase-Activating Protein3
ARHGAP472     

External Ids:    HGNC: 156691   Entrez Gene: 1172892   Ensembl: ENSG000001646917   OMIM: 6096675   UniProtKB: Q8N1033   

Export aliases for TAGAP gene to outside databases

Previous GC identifers: GC06M158897 GC06M159329 GC06M159365 GC06M159426 GC06M159375 GC06M156926


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAGAP Gene:
This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a
Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including
rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript
variants encoding distinct isoforms. (provided by RefSeq, Jul 2013)

GeneCards Summary for TAGAP Gene: 
TAGAP (T-cell activation RhoGTPase activating protein) is a protein-coding gene. Diseases associated with TAGAP include agnosia, and celiac disease, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGAP20.

UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103
Function: May function as a GTPase-activating protein and may play important roles during T-cell activation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAGAP gene promoter:
         S8   Sox5   E2F   E2F-1   AML1a   NF-E2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAGAP promoter sequence
   Search SABiosciences Chromatin IP Primers for TAGAP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAGAP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25.3   Ensembl cytogenetic band:  6q25.3   HGNC cytogenetic band: 6q25.3

TAGAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAGAP gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M159457:  view genomic region     (about GC identifiers)

Start:
159,455,500 bp from pter      End:
159,466,184 bp from pter
Size:
10,685 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103 (See protein sequence)
Recommended Name: T-cell activation Rho GTPase-activating protein  
Size: 731 amino acids; 80703 Da
Secondary accessions: Q2NKM8 Q8NI40 Q96KZ2 Q96QA2
Alternative splicing: 4 isoforms:  Q8N103-1   Q8N103-2   Q8N103-3   Q8N103-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TAGAP: NX_Q8N103

Explore proteomics data for TAGAP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N103

  • TAGAP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TAGAP Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001265662.1  NP_473455.2  NP_620165.1  NP_687034.1  

    ENSEMBL proteins: 
     ENSP00000356033   ENSP00000322650   ENSP00000340217  
    Reactome Protein details: Q8N103
    Human Recombinant Protein Products for TAGAP: 
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    OriGene Custom Protein Services for TAGAP
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    Novus Biologicals TAGAP Protein
    Novus Biologicals TAGAP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TAGAP 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    TAGAP for ontologies           About GeneDecksing



    TAGAP Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for TAGAP 

    Assay Products for TAGAP: 
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    Cloud-Clone Corp. ELISAs for TAGAP 
    Cloud-Clone Corp. CLIAs for TAGAP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARHGAP: Rho GTPase activating proteins

    2 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q8N103

    ProtoNet protein and cluster: Q8N103

    1 Blocks protein domain: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: TAGAP_HUMAN, Q8N103
    Similarity: Contains 1 Rho-GAP domain


    TAGAP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TAGAP_HUMAN, Q8N103
    Function: May function as a GTPase-activating protein and may play important roles during T-cell activation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005085guanyl-nucleotide exchange factor activity IEA--
         
    TAGAP for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tagap):
     reproductive system 

    TAGAP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tagaptm1Bgh for TAGAP

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TAGAP 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TAGAP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TAGAP 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TAGAP 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAGAP
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate TAGAP (see all 37):
    hsa-miR-607 hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-25 hsa-miR-372 hsa-miR-93 hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidTAGAP 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for TAGAP
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    GenScript: all cDNA clones in your preferred vector (see all 3): TAGAP (NM_054114)
    Browse Sino Biological Human cDNA Clones
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                         Customized lentivirus expression plasmids for stable overexpression of TAGAP 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAGAP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TAGAP About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for TAGAP
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    TAGAP for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TAGAP

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    TAGAP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAGAP

    Search CenterWatch for drugs/clinical trials and news about TAGAP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TAGAP gene (4 alternative transcripts): 
    NM_001278733.1  NM_054114.4  NM_138810.3  NM_152133.2  

    Unigene Cluster for TAGAP:

    T-cell activation RhoGTPase activating protein
    Hs.529984  [show with all ESTs]
    Unigene Representative Sequence: NM_054114
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367066(uc011eft.2 uc003qrz.3 uc003qsa.3) ENST00000326965
    ENST00000338313(uc003qsb.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAGAP
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate TAGAP (see all 37):
    hsa-miR-607 hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-25 hsa-miR-372 hsa-miR-93 hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidTAGAP 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TAGAP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAGAP
    Clone
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    OriGene clones in human, mouse for TAGAP (see all 17)
    OriGene ORF clones in mouse, rat for TAGAP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TAGAP (NM_054114)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAGAP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAGAP
    Sirion Biotech Customized lentivirus for stable overexpression of TAGAP 
                         Customized lentivirus expression plasmids for stable overexpression of TAGAP 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TAGAP
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TAGAP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAGAP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAGAP

    Additional mRNA sequence: 

    AF385429.1 AF385430.1 AK057193.1 AK097090.1 AK298686.1 AL832662.1 BC015859.1 BC111731.1 

    8 DOTS entries:

    DT.40312762  DT.40308071  DT.40125502  DT.100673318  DT.100776153  DT.100642280  DT.101979617  DT.97772033 

    24/56 AceView cDNA sequences (see all 56):

    AI253155 NM_152133 BX342972 BX489278 BM991735 AF385429 AA352840 BE676780 
    NM_054114 AK057193 BF591040 AI349366 AW008517 AK097090 AA251806 AI766650 
    AW576600 NM_138810 AF385430 CA306993 AL832662 CA407943 AW407989 AL558315 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TAGAP (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11
    SP1:                                            -     -     -                             -                             -               
    SP2:                                            -     -     -     -     -                 -                             -               
    SP3:                                            -     -     -                             -                                             
    SP4:                                            -     -                                   -                                             
    SP5:                                            -     -     -                                                                           


    ECgene alternative splicing isoforms for TAGAP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAGAP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATATCCTATC
    TAGAP Expression
    About this image


    See TAGAP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TAGAP

    SOURCE GeneReport for Unigene cluster: Hs.529984
        SABiosciences Custom PCR Arrays for TAGAP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAGAP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TAGAP gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tagap1 , 5 T cell activation Rho GTPase activating protein1, 5 75.97(n)1
    69(a)1
      17 (4.82 cM)5
    725361  NM_145968.21  NP_666080.11 
     79260005 
    chicken
    (Gallus gallus)
    Aves TAGAP1 T-cell activation RhoGTPase activating protein 59.39(n)
    50.51(a)
      421662  XM_419701.3  XP_419701.3 
    lizard
    (Anolis carolinensis)
    Reptilia TAGAP6
    Uncharacterized protein
    45(a)
    1 ↔ 1
    1(212590259-212602522)
    zebrafish
    (Danio rerio)
    Actinopterygii tagapb1 T-cell activation RhoGTPase activating protein b 45.61(n)
    35.62(a)
      447809  NM_001004548.1  NP_001004548.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rga-26
    Protein RGA-2
    12(a)
    1 → many
    I(11979440-11985655)


    ENSEMBL Gene Tree for TAGAP (if available)
    TreeFam Gene Tree for TAGAP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TAGAP gene
    ARHGAP202  
    1 SIMAP similar gene for TAGAP using alignment to 1 protein entry:     TAGAP_HUMAN:
    ARHGAP12

    TAGAP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/319 SNPs in TAGAP are shown (see all 319)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs412677591,2
    --159455484(+) AAATAA/GGGAAA 2 -- ds50010--------
    rs122151141,2
    C,F,A,H--159455536(+) ATAATC/TGAACA 2 -- ds5001 ese321Minor allele frequency- T:0.23NA NS EA WA CSA 2473
    rs1835469921,2
    --159455591(+) AATAAC/TTAAGC 2 -- ds50010--------
    rs1867939241,2
    --159455711(+) TTTTTA/CTGGCA 2 -- ds50010--------
    rs104558541,2
    C,A--159455725(+) TGACTC/GCTTGC 2 -- ds50015Minor allele frequency- G:0.24WA CSA NA EA 361
    rs104558551,2
    C,F,A,H--159455764(+) TTTTTA/TATGGT 2 -- ds50019Minor allele frequency- T:0.25NS EA WA CSA NA 770
    rs412677611,2
    C--159455975(+) AGGAAA/GGCAAT 2 -- ut310--------
    rs1460655551,2
    --159456053(+) ACATTA/GTAGGA 2 -- ut310--------
    rs738001401,2
    C--159456099(+) TATAGA/GTGAGT 2 -- ut312Minor allele frequency- G:0.05WA 120
    rs47092641,2
    C,F,A,H--159456141(+) ACCCAC/AATTTA 2 -- ut3115Minor allele frequency- A:0.12NA NS WA EA 1748

    HapMap Linkage Disequilibrium report for TAGAP (159455500 - 159466184 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TAGAP:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886798CNV Gain21882294


    Human Gene Mutation Database (HGMD): TAGAP
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TAGAP
    DNA2.0 Custom Variant and Variant Library Synthesis for TAGAP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609667    OMIM disorders: --

    9 diseases for TAGAP:    About MalaCards
    agnosia    celiac disease    crohn's disease    down syndrome
    type 1 diabetes    rheumatoid arthritis    arthritis    alzheimer's disease
    multiple sclerosis

    2 diseases from the University of Copenhagen DISEASES database for TAGAP:
    Auditory agnosia     Celiac disease

    TAGAP for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): TAGAP
    Human Genome Epidemiology (HuGE) Navigator: TAGAP (14 documents)

    Export disorders for TAGAP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAGAP gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with TAGAP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Newly identified genetic risk variants for celiac disease related to the immune response. (PubMed id 18311140)1, 3, 4 Hunt K.A.... van Heel D.A. (2008)
    2. Genome-wide meta-analysis identifies novel multiple sc lerosis susceptibility loci. (PubMed id 22190364)1, 4 Patsopoulos N.A....de Bakker P.I. (2011)
    3. A meta-analysis of genome-wide association scans iden tifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease. (PubMed id 21298027)1, 4 Festen E.A....Rioux J.D. (2011)
    4. Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)1, 4  ....Compston A. (2011)
    5. Four novel coeliac disease regions replicated in an a ssociation study of a Swedish-Norwegian family cohort. (PubMed id 19693089)1, 4 Amundsen S.S....Sollid L.M. (2010)
    6. Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis. (PubMed id 20647273)1, 4 Hinks A....Thomson W. (2010)
    7. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (PubMed id 21102463)1, 4 Franke A....Parkes M. (2010)
    8. Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)1, 4 Dubois P.C....van Heel D.A. (2010)
    9. Genetic variants at CD28, PRDM1 and CD2/CD58 are asso ciated with rheumatoid arthritis risk. (PubMed id 19898481)1, 4 Raychaudhuri S....Plenge R.M. (2009)
    10. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 117289 HGNC: 15669 AceView: TAGAP Ensembl:ENSG00000164691 euGenes: HUgn117289
    ECgene: TAGAP H-InvDB: TAGAP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAGAP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TAGAP gene:
    Search GeneIP for patents involving TAGAP

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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