TAF9 Gene
protein-coding GIFtS: 64
GCID: GC05M068646
|
|
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated...(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
(Previous symbol: TAF2G)
| |
Aliases
for TAF9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TAF9 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor,32kDa1 2 | | EC 2.7.4.33 8 | | TAF2G1 2 3 5 | | AD-0041 | | TAFII321 2 3 5 | | MGC16031 | | AK61 2 3 | | MGC36471 | | CINAP1 2 3 | | MGC50671 | | TAFII311 2 3 | | TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, G, 32kD1 | | CGI-1371 2 | | CIP2 | | TAFIID321 2 | | MGC:16032 | | Coilin-Interacting Nuclear ATPase Protein2 3 | | MGC:36472 | | Transcription Initiation Factor TFIID 31 KDa Subunit2 3 | | MGC:50672 | | Transcription Initiation Factor TFIID 32 KDa Subunit2 3 | | Adenylate Kinase 62 | | STAF31/322 3 | | Adenylate Kinase Isoenzyme 62 | | TAFII-312 3 | | Adrenal Gland Protein AD-0042 | | TAFII-322 3 | | Coilin Interacting Protein2 | | ATP-AMP Transphosphorylase 62 3 | | Transcription Initiation Factor TFIID 31 KD Subunit2 | | HCINAP1 | | Transcription Initiation Factor TFIID Subunit 92 | | RNA Polymerase II TBP-Associated Factor Subunit G2 3 | | |
Export aliases for TAF9 gene to outside databasesPrevious GC identifers: GC05M068800 GC05M070213 GC05M068617 GC05M068663 GC05M068683 GC05M065603 |
Summaries
for TAF9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TAF9:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position thepolymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as achannel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarilyconserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve ascoactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complexassembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basaltranscription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar butdistinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19.Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: TAF9_HUMAN, Q16594Function: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repressionof distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs arecomponents of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histoneacetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulationof RNA polymerase II-mediated transcription
Gene Wiki entry for TAF9
|
Genomic Views
for TAF9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TAF9 gene promoter:
ATF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TAF9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q11.2-q13.1 Ensembl cytogenetic band: 5q13.2 HGNC cytogenetic band: 5q11.2-q13.1TAF9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M068646: view genomic region
(about GC identifiers)
Start:
|
68,646,811 bp from pter |
End:
|
68,665,840 bp from pter |
Size:
|
19,030 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr5-,PATCHES 69,039,912-69,058,202 |
|
Proteins
for TAF9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KAD6_HUMAN, Q9Y3D8 (See
protein sequence)Recommended Name: Adenylate kinase isoenzyme 6 Size: 172 amino acids; 20061 Da
Subunit: Interacts with COIL (via C-terminus)
Subcellular location: Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmicdistribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells
5 PDB 3D structures from  and Proteopedia  for TAF9:1RKB (3D)
3IIJ (3D)
3IIK (3D)
3IIL (3D)
3IIM (3D)
Secondary accessions: A8MSZ6 Q5F2S9Alternative splicing: 3 isoforms: Q9Y3D8-1 Q16594-1 Q9Y3D8-2 UniProtKB/Swiss-Prot: TAF9_HUMAN, Q16594 (See
protein sequence) Recommended Name: Transcription initiation factor TFIID subunit 9 Size: 264 amino acids; 28974 Da
Subunit: Component of TFIID, the TATA-binding protein-free TAF complex (TFTC), the PCAF complex and the STAGAtranscription coactivator-HAT complex. The PCAF complex consists at least of TADA2L/ADA2, SUPT3H/SPT3, TADA3L/ADA3,TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP. The STAGA transcriptioncoactivator-HAT complex consists at least of SUPT3H, GCN5L2, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAPand TAF9. Binds N-terminal domain of p53/TP53 which is essential for transcription. Component of some MLL1/MLLcomplex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultativecomponents BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2,RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Binds TFIIB and the Herpes simplex virusactivator VP16. Forms a heterodimer with TAF6/TAFII80 in a complex with the TAF4B/TAFII105-TAF12/TAFII20 heterodimer.Also interacts with TAF5. Binds directly DNA. Increased DNA binding when complexed with TAF6/TAFII80
Subcellular location: Nucleus
Secondary accessions: D3DWA3 Q5U0D1 Q9BTS1Alternative splicing: 3 isoforms: Q16594-1 Q9Y3D8-1 Q9Y3D8-2 Explore the universe of human proteins at neXtProt for TAF9: NX_Q16594
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16594
4/5 DME Specific Peptides for TAF9 (Q9Y3D8) (see all 5)
TAF9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001015891.1 NP_001015892.1 NP_003178.1 NP_057367.1
ENSEMBL proteins: ENSP00000370201 ENSP00000370197 ENSP00000420947 ENSP00000421873 ENSP00000217893 ENSP00000425944 ENSP00000427343 ENSP00000426283 ENSP00000425798 ENSP00000427617 ENSP00000370193 Reactome Protein details: Q16594
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
TAF9 for ontologies About GeneDecksing
TAF9 Antibody Products:
Assay Products for TAF9: |
Protein
Domains /
Families
for TAF9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TAF9 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y3D8Graphical View of Domain Structure for InterPro Entry Q16594ProtoNet protein and cluster: Q9Y3D8 UniProtKB/Swiss-Prot: KAD6_HUMAN, Q9Y3D8Similarity: Belongs to the adenylate kinase family. AK6 subfamilyUniProtKB/Swiss-Prot: TAF9_HUMAN, Q16594Similarity: Belongs to the TAF9 family |
Function
for TAF9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KAD6_HUMAN, Q9Y3D8Function: Broad activity as an NMP kinase. AMP and dAMP are the preferred substrates of all tested NMPs, but CMP anddCMP are also good substrates. IMP can be phosphorylated, but to a much lesser extent. Adenylate and cytidylate canserve as phosphate acceptorsCatalytic activity: ATP + AMP = 2 ADPBiophysicochemical properties: Kinetic parameters: KM=75.3 uM for ATP; Vmax=1.27 umol/min/mg enzyme; UniProtKB/Swiss-Prot: TAF9_HUMAN, Q16594Function: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repressionof distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs arecomponents of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histoneacetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulationof RNA polymerase II-mediated transcriptionInduction: 6 to 8-fold by apoptotic signalsEnzyme Number (IUBMB): EC 2.7.4.31 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): TAF9 (NM_003187) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TAF9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF9 |
Gene Ontology (GO): 5/11 molecular function terms (GO ID links to tree view) (see all 11): About this table
TAF9 for ontologies About GeneDecksing
|
Pathways & Interactions
for TAF9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of RNA Pol II elongation complex | | | 2 | Assembly of RNA Polymerase-II Initiation Complex | | | 3 | HIV Infection | | | 4 | Late Phase of HIV Life Cycle | | | 5 | Transcription | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for TAF9
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TAF9 (see all 7)
2  GeneGo (Thomson Reuters) Pathways for TAF9
4  BioSystems Pathways for TAF9
5/19 
Reactome Pathways for TAF9 (see all 19)
2 
Kegg Pathways (Kegg details for TAF9):
TAF9 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TAF9
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/569 Interacting proteins for TAF9 (Q165941, 2, 3 ENSP000002178934 Q9Y3D81, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 569)About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006352 | DNA-dependent transcription, initiation |
-- | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0006368 | transcription elongation from RNA polymerase II promoter |
TAS | -- | | GO:0006974 | response to DNA damage stimulus |
IC | 11278372 |
TAF9 for ontologies About GeneDecksing
|
Drugs & Compounds
for TAF9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TAF9
Search CenterWatch for drugs/clinical trials and news about TAF9
|
Transcripts
for TAF9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TAF9 gene (4 alternative transcripts): NM_001015891.1 NM_001015892.1 NM_003187.4 NM_016283.4 Unigene Cluster for TAF9: TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa Hs.653163 [show with all ESTs]Unigene Representative Sequence: BC03332012 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380822(uc003jwa.3) ENST00000502819 ENST00000380818(uc003jwb.3)
ENST00000512561 ENST00000506736(uc003jwc.1) ENST00000217893(uc003jwe.1)
ENST00000503245 ENST00000509462 ENST00000504109 ENST00000512152 ENST00000508954
ENST00000328663(uc003jwf.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): TAF9 (NM_003187) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TAF9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF9 |
Additional cDNA sequence: AF110777.1 AF151895.1 AJ878880.1 AJ878881.1 BC003400.1 BC007349.2 BC007426.2 BC033320.1 BT019652.1 U21858.1 U25112.1 U30504.1 24/28 DOTS entries (see all 28): DT.100819169 DT.100801079 DT.452110 DT.120842325 DT.95258926 DT.120842183 DT.443071 DT.70103909 DT.422686 DT.120842396 DT.40307992 DT.419165 DT.121504121 DT.100703220 DT.100819170 DT.120842191 DT.97862317 DT.100685961 DT.100819171 DT.65286751 DT.95192818 DT.95193472 DT.120842176 DT.120842177 24/450 AceView cDNA sequences (see all 450): BF003040 NM_003187 AA807382 AI636657 BC003400 U21858 BG942858 AA186668 BQ434615 BI913284 AA321648 BM807509 AW083156 CB529171 BM832752 T36197 AU102679 AI337508 BM915623 BQ772517 CA421215 AA632383 BU620877 AA845528
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TAF9 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | · | 7f | · | 7g | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | |
| SP2: | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TAF9
|
Expression
for TAF9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TAF9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGATGTTT
About this image
See TAF9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TAF9
SOURCE GeneReport for Unigene cluster: Hs.653163
SABiosciences Custom PCR Arrays for TAF9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TAF9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAF9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF9 |
Orthologs
for TAF9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TAF9 gene from 10/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Taf91 , 5 |
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated more1, 5 |
91.09(n)1
96.18(a)1 |
|
13 (53.23 cM)5
1081431 NM_001015889.21 NP_001015889.11
1006513435 |
chicken
(Gallus gallus) |
Aves |
TAF91 |
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated more |
73.86(n)
86.27(a) |
|
422152 XM_420153.3 XP_420153.2 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
84(a) |
1 → many |
GL343400.1(393367-398156) |
African clawed frog
(Xenopus laevis) |
Amphibia |
480119002 |
-- |
74.15(n) |
|
48011900 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb16h032 |
Transcribed sequence with moderate similarity to protein more |
74.12(n) |
|
BM141601.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
e(y)11 , 3 |
transcription initiation from Pol II
promoter more3
enhancer of yellow 11 |
56(a)3
53.09(n)1
57.78(a)1 |
|
1 16E13
327621 NM_078667.31 NP_523391.31 |
worm
(Caenorhabditis elegans) |
Secernentea |
taf-96 |
TAF (TBP-associated transcription factor) family m... |
28(a) |
1 → many |
III(13624173-13625840) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
FAP7(YDL166C)4
TAF91 |
Essential NTPase required for small ribosome subunit more4
Taf9p1 |
44.96(n)1
34.11(a)1 |
|
4(164042-163449)4
8552761 NP_013963.11 8513884
NP_010115.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
TAFII216 |
transcription initiation factor TFIID subunit D7 |
34(a) |
1 → many |
1(20213967-20215223) |
rice
(Oryza sativa) |
Liliopsida |
---- |
transcription initiation factor IID, putative |
29(a)13(a) |
many ↔ manymany ↔ many |
3(16793108-16798360) 7(25218515-25222059) |
ENSEMBL Gene Tree for TAF9 (if available)
TreeFam Gene Tree for TAF9 (if available) |
Paralogs
for TAF9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TAF9 gene
- TAF9B2
1 SIMAP similar gene for TAF9 using alignment to 8 protein entries: KAD6_HUMAN (see all proteins):TAF9B
TAF9 for paralogs About GeneDecksing
5/11 Pseudogenes.org Pseudogenes for TAF9 (see all 11)
PGOHUM00000239409 PGOHUM00000251003 PGOHUM00000239738 PGOHUM00000234652 PGOHUM00000234653
|
Genomic Variants
for TAF9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TAF9 (68646811 - 68665840 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TAF9
1 CNV: 0283 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAF9 |
|
Disorders
/ Diseases
for TAF9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TAF9 for disorders About GeneDecksing
OMIM gene information: 600822
OMIM disorders: --
6  diseases for TAF9: About MalaCardsspinal muscular atrophy muscular atrophy retinal degeneration retinitis
ataxia immunodeficiency
1 disease from the University of Copenhagen DISEASES database for TAF9:Spinal muscular atrophy Human Genome Epidemiology (HuGE) Navigator: TAF9 (1 document)
Export disorders for TAF9 gene to outside databases
|
Publications
for TAF9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TAF9 gene, integrated from 9 sources (see all 83):
(articles sorted by number of sources associating them with TAF9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. (PubMed id 7667268)1, 2, 9 Hisatake K.... Roeder R.G. (1995)
- Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus. (PubMed id 16079131)1, 2, 9 Santama N....Lamond A.I. (2005)
- Core promoter binding by histone-like TAF complexes. (PubMed id 15601843)1, 2 Shao H.... Dikstein R. (2005)
- TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. (PubMed id 15899866)1, 2 Frontini M.... Tora L. (2005)
- The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus. (PubMed id 15630091)1, 3 Ren H....Su X.D. (2005)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo. (PubMed id 11564863)1, 2 Martinez E.... Roeder R.G. (2001)
- Mapping and mutational analysis of the human TAF2G gene encoding a p53 cofactor. (PubMed id 10191103)1, 3 Evans S.C....Lozano G. (1999)
- Histone-like TAFs within the PCAF histone acetylase complex. (PubMed id 9674425)1, 2 Ogryzko V.V.... Nakatani Y. (1998)
|
External Searches for TAF9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TAF9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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|
|
Other Databases showing TAF9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TAF9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TAF9 gene:
Search GeneIP for patents involving TAF9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TAF9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TAF9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAF9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF9 | | | OriGene Protein Over-expression Lysate for TAF9 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for TAF9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TAF9 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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