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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TAF8 Gene

protein-coding GIFtS: 52
GCID: GC06P042018

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated...

(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
(Previous symbol: TBN)

Explore 1 disease affiliated with
TAF8 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
TAF8 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 43kDa¹ ²		TBP-Associated Factor 8² ³
TBN¹ ² ³		FLJ32821¹
TAF(II)43¹ ²		Taube Nuss Homolog (Mouse)¹
TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, A, 45/50kDa¹ ²		43²
Protein Taube Nuss² ³		II²
Transcription Initiation Factor TFIID 43 KDa Subunit² ³		TAF²
TAFII-43² ³		Taube Nuss Homolog²
TAFII43² ³		TBP-Associated Factor TAFII43²
HTAFII43¹		TBP-Associated Factor, RNA Polymerase II, 43 KD²
TBP-Associated Factor 43 KDa² ³		Transcription Initiation Factor TFIID Subunit 8²

External Ids:	HGNC: 17300¹	Entrez Gene: 129685²	Ensembl: ENSG00000137413⁷	OMIM: 609514⁵	UniProtKB: Q7Z7C8³

Export aliases for TAF8 gene to outside databases

Previous GC identifers: GC00U991138 GC06P042127 GC06P041736

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAF8:

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of

the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the

assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The

protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID

including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but

their biological validity has not been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Function: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by

RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of

preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts.

Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell

mass which constitute the pluripotent cell population of the early embryo (By similarity)

Gene Wiki entry for TAF8

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TAF8 gene promoter:
c-Fos TBP AP-1 TFIID ATF-2 c-Jun AP-2gamma
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TAF8 promoter sequence

Search SABiosciences Chromatin IP Primers for TAF8

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1

TAF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF8 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06P042018: view genomic region (about GC identifiers)

Start:	42,018,251 bp from pter	End:	42,055,199 bp from pter
Size:	36,949 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8 (See protein sequence)

Recommended Name: Transcription initiation factor TFIID subunit 8

Size: 310 amino acids; 34262 Da

Subunit: TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with

TBP, TAF1, TAF6, TAF10, TAF11 and TAF13. Component also of a small TAF complex (SMAT) containing TAF8, TAF10 and

SUPT7L. Forms a heterodimer with TAF10. Interaction with TAF10 is mediated mainly via its histone fold domain while

interaction with SUPT7L is via its C-terminal region

Subcellular location: Nucleus. Cytoplasm (By similarity). Note=Localized in the cytoplasm and transported from the

cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell (By

similarity)

Miscellaneous: 'Taube nuss' means "empty nut' in German

Sequence caution: Sequence=BAB71460.1; Type=Frameshift; Positions=240;

Secondary accessions: Q5T0K1 Q8N4R9 Q96M52

Alternative splicing: 3 isoforms: Q7Z7C8-1 Q7Z7C8-2 Q7Z7C8-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TAF8: NX_Q7Z7C8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q7Z7C8

TAF8 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_612639.2

ENSEMBL proteins:

ENSP00000362069 ENSP00000411900 ENSP00000417867 ENSP00000362073 ENSP00000362068

ENSP00000417760 ENSP00000418029 ENSP00000417738

Human Recombinant Protein Products:

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	Uscn Proteins for TAF8

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005669	transcription factor TFIID complex	IDA	14580349
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	--	--
GO:0048471	perinuclear region of cytoplasm	IDA	15870280

TAF8 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for TAF8

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TAF8 for domains About GeneDecksing

3 InterPro domains/families:

IPR006565 BTP

IPR019473 TFIID_su8_C

IPR009072 Histone-fold

Graphical View of Domain Structure for InterPro Entry Q7Z7C8

ProtoNet protein and cluster: Q7Z7C8

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Domain: Ectopic expression of the histone fold domain acts as a dominant-negative mutant resulting in differentiation

inhibition

Similarity: Belongs to the TAF8 family

Similarity: Contains 1 histone-fold domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Function: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by

RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of

preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts.

Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell

mass which constitute the pluripotent cell population of the early embryo (By similarity)

Induction: Induced with triglyceride accumulation

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAF8
		8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate TAF8 (see all 17):
		hsa-miR-520d-5p hsa-miR-340 hsa-miR-29b-1* hsa-miR-105 hsa-miR-3150b-3p hsa-miR-3121-3p hsa-miR-580 hsa-miR-3163

		SwitchGear 3'UTR luciferase reporter plasmid: TAF8 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF8

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0005515	protein binding	IPI	15870280
GO:0046982	protein heterodimerization activity	IEA	--

TAF8 for ontologies About GeneDecksing

Animal Models:
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Taf8):

embryogenesis

mortality/aging

TAF8 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

HIV Infection

Transcription Ligand-Dependent Transcription of Retinoid-Target genes

0.28

Transcription_Ligand-Dependent Transcription of Retinoid-Target genes

0.28

Assembly of RNA Polymerase-II Initiation Complex

Basal transcription factors

0.49

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for TAF8

Transcription Ligand-Dependent Transcription of Retinoid-Target genes

1 GeneGo (Thomson Reuters) Pathway for TAF8

Transcription Ligand-Dependent Transcription of Retinoid-Target genes

1 Kegg Pathway (Kegg details for TAF8):

Basal transcription factors

TAF8 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for TAF8

STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

5/23 Interacting proteins for TAF8 (Q7Z7C8³ ENSP00000362068⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TAF9	Q16594³, ENSP00000217893⁴	I2D: score=2 STRING: ENSP00000370201 STRING: ENSP00000217893
TAF5	Q15542³, ENSP00000358854⁴	I2D: score=3 STRING: ENSP00000358854
TAF1	P21675³, ENSP00000276072⁴	I2D: score=2 STRING: ENSP00000276072
TAF11	Q15544³, ENSP00000354633⁴	I2D: score=2 STRING: ENSP00000354633
TAF2	Q6P1X5³, ENSP00000367406⁴	I2D: score=2 STRING: ENSP00000367406

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001833	inner cell mass cell proliferation	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0030154	cell differentiation	IEA	--
GO:0045598	regulation of fat cell differentiation	IDA	14580349
GO:0045893	positive regulation of transcription, DNA-dependent	IDA	14580349

TAF8 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TAF8
Search CenterWatch for drugs/clinical trials and news about TAF8

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TAF8 gene:

NM_138572.2

Unigene Cluster for TAF8:

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

Hs.520122 [show with all ESTs]

Unigene Representative Sequence: NM_138572

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372978(uc003orr.3) ENST00000456846 ENST00000494547 ENST00000372982(uc003oru.1 uc003orv.1)

ENST00000372977(uc003ors.3 uc003ort.3 uc011dun.2) ENST00000472818

ENST00000486070 ENST00000482926 ENST00000465926 ENST00000482432

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAF8
		8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate TAF8 (see all 17):
		hsa-miR-520d-5p hsa-miR-340 hsa-miR-29b-1* hsa-miR-105 hsa-miR-3150b-3p hsa-miR-3121-3p hsa-miR-580 hsa-miR-3163

		SwitchGear 3'UTR luciferase reporter plasmid: TAF8 3' UTR sequence

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		GenScript: all cDNA clones in your preferred vector: TAF8 (NM_138572)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF8

Additional cDNA sequence:

AF086309.1 AF465841.1 AK057383.1 AK303097.1 AL833401.1 BC119678.1 BC119679.1

16 DOTS entries:

DT.100773233 DT.421486 DT.121342217 DT.108065 DT.97795211 DT.97846170 DT.40292936 DT.75145214

DT.95150036 DT.97846169 DT.121342110 DT.92036337 DT.95357755 DT.97812883 DT.97846168 DT.121342254

24/128 AceView cDNA sequences (see all 128):

BM758722 BM758723 BM770626 BM785433 CD636440 CD514233 BM755747 BM758732

BM741104 BM759016 BF432334 BM758051 BU189966 BM741109 BM749804 BM756230

CD636453 AW815571 BQ437299 BM758910 BM750602 BM758085 BM746812 BM758091

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TAF8 (see all 8) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b
SP1:									-				-						-						-		-				-
SP2:									-				-						-						-
SP3:									-				-						-
SP4:													-						-
SP5:									-				-

ECgene alternative splicing isoforms for TAF8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TAF8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGATTAAAA

About this image

TAF8 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Inner Cell Mass

Inner Cell Mass Cells

Early Embryo

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TAF8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TAF8

SOURCE GeneReport for Unigene cluster: Hs.520122

SABiosciences Custom PCR Arrays for TAF8

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF8

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TAF8 gene from 7/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Taf8^{1 , 5}	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more^{1, 5}	89.83(n)¹ 95.13(a)¹		17 (23.33 cM)⁵ 63856¹ NM_022015.3¹ NP_071298.1¹ 47488050⁵
chicken (Gallus gallus)	Aves	TAF8¹	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more	82.38(n) 94.26(a)		419929 NM_001030923.1 NP_001026094.1
lizard (Anolis carolinensis)	Reptilia	TAF8⁶	--	91(a)	1 ↔ 1	4(119140502-119150508)
African clawed frog (Xenopus laevis)	Amphibia	tbn-prov²	taube nuss	77.06(n)		BC043877.1
zebrafish (Danio rerio)	Actinopterygii	zgc56401²	similar to taube nuss	74.7(n)		393256 BC049422.1
fruit fly (Drosophila melanogaster)	Insecta	Taf8¹	TBP-associated factor 8	51.39(n) 43.94(a)		32792 NM_078673.3 NP_523397.1
worm (Caenorhabditis elegans)	Secernentea	taf-8⁶	TAF (TBP-associated transcription factor) family m...	15(a)	1 ↔ 1	II(9669265-9671440)

ENSEMBL Gene Tree for TAF8 (if available)
TreeFam Gene Tree for TAF8 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs62415893^1,2	C,	--	42018640(+)	`ATATTT/GAGCTT`	1	--	int¹		3		NA EA	242
rs7765890^1,2	C,H,	--	42018653(+)	`TTACTT/GTTTTG`	1	--	int¹		4		NS EA	522
rs7770149^1,2	C,H,	--	42018878(+)	`GGGACC/TGTACG`	1	--	int¹		12		NA WA CSA EA	374
rs11967378^1,2	C,F,A,H,	--	42018883(+)	`TGTACG/TTTTTA`	1	--	int¹		19		NS EA NA WA	2522
rs182612449^1,2		--	42018906(+)	`AGTGGG/TCTCTG`	1	--	int¹		0	--	--	--	--
rs138016737^1,2		--	42018929(+)	`CTTGGA/GTGCTC`	1	--	int¹		0	--	--	--	--
rs149515714^1,2		--	42018936(+)	`GCTCAA/GTTTTT`	1	--	int¹		0	--	--	--	--
rs201585310^1,2	F	--	42019037(+)	`CACGTA/GTGAAC`	1	--	int¹		1		EU	593
rs74710424^1,2	C,	--	42019120(+)	`CACTAA/CCCCTG`	2	N T	mis¹		0	--	--	--	--
rs143913354^1,2	C,	--	42019270(+)	`AACACC/TTGGCC`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TAF8 (42018251 - 42055199 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TAF8: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TAF8 for disorders           About GeneDecksing

OMIM gene information: 609514    OMIM disorders: --

1 disease for TAF8:    About MalaCards

immunodeficiency

Human Genome Epidemiology (HuGE) Navigator: TAF8 (1 document)

Export disorders for TAF8 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TAF8 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with TAF8)

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Identification of a small TAF complex and its role in the assembly of TAF-containing complexes. (PubMed id 17375202)^{1, 2, 9} Demeny M.A.... Tora L. (2007)
The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. (PubMed id 14580349)^{1, 2, 9} Guermah M.... Roeder R.G. (2003)
The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners. (PubMed id 15870280)^{1, 2} Soutoglou E....Tora L. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Genomics and transcription analysis of human TFIID. (PubMed id 9569032)^{1, 9} Purrello M....Roeder R. (1998)
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)¹ Chapuis J....Lambert J.C. (2009)
STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation. (PubMed id 17967894)¹ Liu X....Martinez E. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 129685	HGNC: 17300	AceView: TBN	Ensembl:ENSG00000137413	euGenes: HUgn129685
ECgene: TAF8	Kegg: 129685	H-InvDB: TAF8

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TAF8	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TAF8 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TAF8 gene:
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GeneCards and IP:
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TAF8 (Gene Symbol)
TAF8 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 43kDa
TBN
TAF(II)43
TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, A, 45/50kDa
Protein Taube Nuss
Transcription Initiation Factor TFIID 43 KDa Subunit
TAFII-43
TAFII43
HTAFII43
TBP-Associated Factor 43 KDa
TBP-Associated Factor 8
FLJ32821
Taube Nuss Homolog (Mouse)
43
II
TAF
Taube Nuss Homolog
TBP-Associated Factor TAFII43
TBP-Associated Factor, RNA Polymerase II, 43 KD
Transcription Initiation Factor TFIID Subunit 8

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TAF8 Gene

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