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TAF8 Gene

protein-coding GIFtS: 53

GC06P042127

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa, taube nuss homolog (mouse) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: TBN)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
43 ^²
FLJ32821 ^¹, ²
II ^²
OTTHUMP00000016392 ^²
TAF ^²
TAF(II)43 ^¹, ²
TAFII43 ^², ³
TBN ^², ³
hTAFII43 ^³

Descriptions
Protein taube nuss ^³
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa ^²
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50 kD ^²
TAF8 RNA polymerase II, TATA box binding protein-associated factor, 43kDa ^¹
TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa ^¹, ²
TBP-associated factor 43 kDa ^³
TBP-associated factor 8 ^², ³
TBP-associated factor TAFII43 ^²
TBP-associated factor, RNA polymerase II, 43 kD ^²
Transcription initiation factor TFIID 43 kDa subunit ^³
taube nuss homolog ^²
taube nuss homolog (mouse) ^¹

External Ids
HGNC: 17300¹
Entrez Gene: 129685²
UniProtKB: Q7Z7C8³
Ensembl: ENSG00000137413⁷

Search outside databases for aliases for TAF8 gene

Previous GC identifer: GC00U991138

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TAF8:

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are

integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core

promoter of many genes and nucleates the assembly of a transcription preinitiation complex

containing RNA polymerase II and other initiation factors. The protein encoded by this gene

contains an H4-like histone fold domain, and interacts with several subunits of TFIID including

TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been

described, but their biological validity has not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Function: Transcription factor TFIID is one of the general factors required for accurate and

regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent

transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes,

however, does not seem to play a role in differentiation of myoblasts. Required for the

integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell

mass which constitute the pluripotent cell population of the early embryo (By similarity)

Gene Wiki entry for TAF8

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1

TAF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06P042127: (about GC identifiers)

Start:	42,126,229 bp from pter
End:	42,163,170 bp from pter
Size:	36,942 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000006.10 NT_007592.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8 (See protein sequence)

Recommended Name: Transcription initiation factor TFIID subunit 8

Size: 310 amino acids; 34262 Da

Subunit: TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors

(TAFs). Interacts with TBP, TAF1, TAF6, TAF10, TAF11 and TAF13. Component also of a small TAF

complex (SMAT) containing TAF8, TAF10 and SUPT7L. Forms a heterodimer with TAF10. Interaction with

TAF10 is mediated mainly via its histone fold domain while interaction with SUPT7L is via its

C-terminal region

Subcellular location: Nucleus. Cytoplasm (By similarity). Note=Localized in the cytoplasm and

transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional

or developmental state of the cell (By similarity)

Miscellaneous: 'Taube nuss' means "empty nut' in German

Sequence caution: Sequence=BAB71460.1; Type=Frameshift; Positions=240;

Secondary accessions: Q5T0K1 Q8N4R9 Q96M52

Alternative splicing: 4 isoforms: Q7Z7C8-1 Q7Z7C8-2 Q7Z7C8-3 Q7Z7C8-4

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_612639.2

ENSEMBL proteins:

ENSP00000362069 ENSP00000312792 ENSP00000362073 ENSP00000362068

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TAF8)
	Human Recombinant Proteins from Abnova (TBN)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005669	transcription factor TFIID complex	IDA	14580349
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for TAF8:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TAF8), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TBN)
	Novus Biologicals Antibodies for TAF8

Assays for TAF8:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q7Z7C8

ProtoNet protein and cluster: Q7Z7C8

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Domain: Ectopic expression of the histone fold domain acts as a dominant-negative mutant resulting

in differentiation inhibition

Similarity: Belongs to the TAF8 family

Similarity: Contains 1 histone-fold domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF8)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138572

Applied Biosystems Silencer® siRNAs for TAF8

Sigma-Aldrich siRNA for TAF8

Sigma-Aldrich shRNA for TAF8

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TAF8
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_138572
Myc/DDK tagged cDNA clone in CMV expression vector: NM_138572
untagged cDNA clones in CMV expression vector (see all 3): BC033728

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_138572

UniProtKB/Swiss-Prot: TAF8_HUMAN, Q7Z7C8

Function: Transcription factor TFIID is one of the general factors required for accurate and

regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent

transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes,

however, does not seem to play a role in differentiation of myoblasts. Required for the

integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell

mass which constitute the pluripotent cell population of the early embryo (By similarity)

Induction: Induced with triglyceride accumulation

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Taf8):

embryogenesis

lethality-prenatal/perinatal

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0005515	protein binding	IDA	14580349
GO:0016563	transcription activator activity	IDA	14580349

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for TAF8

5/90 Interacting proteins for TAF8 (ENSP00000362073³) via UniProtKB, MINT, and/or STRING (see all 90 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TAF1	ENSP00000276072³	STRING (score=.999)
TAF10	ENSP00000299424³	STRING (score=.999)
TAF11	ENSP00000354633³	STRING (score=.999)
TAF12	ENSP00000263974³	STRING (score=.999)
TAF4	ENSP00000252996³	STRING (score=.999)

About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001833	inner cell mass cell proliferation	IEA	--
GO:0006350	transcription	IEA	--
GO:0007275	multicellular organismal development	IEA	--
GO:0030154	cell differentiation	IEA	--
GO:0045598	regulation of fat cell differentiation	IDA	14580349

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TAF8

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF8)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138572

Sigma-Aldrich siRNA for TAF8

Sigma-Aldrich shRNA for TAF8

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_138572

REFSEQ mRNAs for TAF8 gene:

NM_138572.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_138572

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_138572
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_138572
                                 untagged cDNA clones in CMV expression vector (see all 3): BC033728

Additional cDNA sequence:

AF086309.1 AF465841.1 AK057383.1 AK303097.1 AL833401.1 BC119678.1 BC119679.1

16 DOTS entries:

DT.100773233 DT.421486 DT.121342217 DT.108065 DT.97795211 DT.97846170 DT.40292936 DT.75145214

DT.95150036 DT.97846169 DT.121342110 DT.92036337 DT.95357755 DT.97812883 DT.97846168 DT.121342254

24/128 AceView cDNA sequences (see all 128 ):

BM758180 BQ437299 BM758910 BM756230 AW815571 BM746812 BM758727 BM758732

CD636453 BM758091 BM756275 BM749804 BU189966 BM757582 BM758085 BM758051

BM758723 CA430966 BM755747 BM741104 BQ669192 BM750602 CD514233 BM759016

Unigene Cluster for TAF8:

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

Hs.520122 [show with all ESTs]

Unigene Representative Sequence: NM_138572

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TAF8 (see all 8 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b
SP1:									-				-						-						-		-				-
SP2:									-				-						-						-
SP3:									-				-						-
SP4:													-						-
SP5:									-				-

About this scheme

ECgene alternative splicing isoforms for TAF8

4 Ensembl transcripts including schematic representations:

ENST00000372978 ENST00000320973 ENST00000372982 ENST00000372977

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TAF8 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TAF8

¹ / ²

9 probe-sets matching TAF8 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
76908_at²	U95-E	1	1.00	1.00	0.80	0.91	--	--	--	--	--
87690_at²	U95-E	1	1.00	1.00	0.67	1.16	--	--	--	--	--
87692_at²	U95-E	1	0.81	1.00	0.65	0.93	--	--	--	--	--
229412_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
229412_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1556178_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1556978_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1556176_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1552494_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks TAF8 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CAGATTAAAA

SOURCE GeneReport for Unigene cluster: Hs.520122

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TAF8 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TAF8¹	--	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more	91.72(n) 98.06(a)	481798 XM_538919.2 XP_538919.2
chimpanzee (Pan troglodytes)	TAF8¹	--	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more	99.57(n) 100(a)	462691 XM_518472.2 XP_518472.2
cow (Bos taurus)	TAF8¹	--	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more	92.58(n) 98.39(a)	539938 XM_590421.3 XP_590421.2
rat (Rattus norvegicus)	Taf8¹	--	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more	88.96(n) 95.78(a)	316216 XM_236948.4 XP_236948.3
mouse (Mus musculus)	Taf8^{1, 5}	17⁵	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated more^{1, 5}	89.83(n)¹ 95.13(a)¹	63856¹ NM_022015.3¹ NP_071298.1¹ AF222802⁵ AK045108⁵ (see all 13)

About this table Species with no ortholog for TAF8

ENSEMBL Gene Tree for TAF8

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/226 NCBI SNPs in TAF8 are shown (see all 226 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 90)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs6906808^1,2	A,C,F,H	42155972(+)	`TTGTTG/TTTATC`	1	--	ut3¹		18		EU EA WA NS NA	1282
	rs3800288^1,2	A,C,F,H	42154057(+)	`TACAAA/GGAAGA`	1	--	ut3¹		13		EU EA WA NA	1230
	rs7745547^1,2	A,C,F,H	42156668(+)	`CAGCAA/GTGTGG`	1	--	ng3¹		12		EU EA WA NA	1056
	rs9381132^1,2	A,C,F,H	42156821(+)	`TGTCAA/GTAGCT`	1	--	ng3¹		4		EU EA WA	418
--	rs12209078^1,2	A	42124774(+)	`tgagaC/Tggagt`	1	--	ng5¹		0	--	--	--	--
	rs11757642^1,2	H	42154536(+)	`TGGGGT/GTTAAA`	1	--	ut3¹		4		EU EA WA	416
--	rs9462767^1,2	A	42156906(+)	`gtgtgC/Tgcgtg`	1	--	ng3¹		0	--	--	--	--
--	rs12210689^1,2	A	42125299(+)	`ACTGGC/TAGCCG`	1	--	ng5¹		0	--	--	--	--
	rs9471751^1,2	H	42156645(+)	`CTTAAT/ATTGTG`	1	--	ng3¹		4		EU EA WA	416
	rs6901760^1,2	H	42125456(+)	`AGTGGG/CCCATT`	1	--	ng5¹		4		EU EA WA	416

About this table

HapMap Linkage Disequilibrium images for TAF8 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 609514

Human Genome Epidemiology Navigator: TAF8 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/21 PubMed articles for TAF8 gene (see all 21 ):

The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. (PubMed id 14580349)^{1, 3, 4} Guermah M.... Roeder R.G. (2003)
The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners. (PubMed id 15870280)^{3, 4} Soutoglou E....Tora L. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Identification of a small TAF complex and its role in the assembly of TAF-containing complexes. (PubMed id 17375202)^{1, 4} Demeny M.A....Tora L. (2007)
Genomics and transcription analysis of human TFIID. (PubMed id 9569032)^{1, 3} Purrello M....Roeder R. (1998)
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)³ Chapuis J....Lambert J.C. (2009)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)⁴ Mungall A.J.... Beck S. (2003)
A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. (PubMed id 11963920)³ Tora L. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 129685	HGNC: 17300	AceView: TBN	Ensembl:ENSG00000137413	euGenes: HUgn129685
ECgene: TAF8	H-InvDB: TAF8

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for TAF8
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for TAF8:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TAF8-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TAF8		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TAF8		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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Antibodies for TAF8

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TAF8 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for TAF8

Summaries
for TAF8

Genomic Location
for TAF8

Proteins
for TAF8

Protein Domains/
Families
for TAF8

Gene Function
for TAF8

Pathways & Interactions
for TAF8

Drugs & Compounds
for TAF8

Transcripts
for TAF8

Expression
for TAF8

Orthologs
for TAF8

Paralogs
for TAF8

SNPs/Variants
for TAF8

Disorders & Mutations
for TAF8

Medical News
for TAF8

Publications
for TAF8

Search for TAF8

Genome Databases showing TAF8

Other Databases showing TAF8

Specialized Databases showing TAF8

Licensable Technologies
for TAF8

Services
for TAF8

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TAF8 (Gene Symbol)
43
FLJ32821
II
OTTHUMP00000016392
TAF
TAF(II)43
TAFII43
TBN
hTAFII43
Protein taube nuss
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50 kD
TAF8 RNA polymerase II, TATA box binding protein-associated factor, 43kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa
TBP-associated factor 43 kDa
TBP-associated factor 8
TBP-associated factor TAFII43
TBP-associated factor, RNA polymerase II, 43 kD
Transcription initiation factor TFIID 43 kDa subunit
taube nuss homolog
taube nuss homolog (mouse)

TAF8 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor TAF8

Summariesfor TAF8

Genomic Locationfor TAF8

Proteinsfor TAF8

Protein Domains/Familiesfor TAF8

Gene Functionfor TAF8

Pathways & Interactionsfor TAF8

Drugs & Compoundsfor TAF8

Transcriptsfor TAF8

Expression for TAF8

Orthologsfor TAF8

Paralogsfor TAF8

SNPs/Variantsfor TAF8

Disorders & Mutationsfor TAF8

Medical Newsfor TAF8

Publicationsfor TAF8

Search for TAF8

Genome Databases showing TAF8

Other Databases showing TAF8

Specialized Databases showing TAF8

Licensable Technologiesfor TAF8

Servicesfor TAF8

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TAF8

Summaries
for TAF8

Genomic Location
for TAF8

Proteins
for TAF8

Protein Domains/
Families
for TAF8

Gene Function
for TAF8

Pathways & Interactions
for TAF8

Drugs & Compounds
for TAF8

Transcripts
for TAF8

Expression
for TAF8

Orthologs
for TAF8

Paralogs
for TAF8

SNPs/Variants
for TAF8

Disorders & Mutations
for TAF8

Medical News
for TAF8

Publications
for TAF8

Licensable Technologies
for TAF8

Services
for TAF8