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TAF7L Gene

protein-coding   GIFtS: 55
GCID: GC0XM100523

TAF7-Like RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated...

(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
(Previous symbol: TAF2Q)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TAF7-Like RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated
Factor, 50kDa1 2
     RNA Polymerase II TBP-Associated Factor Subunit Q2 3
TAF2Q1 2 3 5     TATA Box-Binding Protein-Associated Factor 50 KDa2 3
Cancer/Testis Antigen 401 2 3     TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, Q1
Transcription Initiation Factor TFIID 50 KDa Subunit2 3     TBP-Associated Factor, RNA Polymerase II, Q2
CT402 3     Transcription Initiation Factor TFIID Subunit 7-Like2

External Ids:    HGNC: 115481   Entrez Gene: 544572   Ensembl: ENSG000001023877   OMIM: 3003145   UniProtKB: Q5H9L43   

Export aliases for TAF7L gene to outside databases

Previous GC identifers: GC0XM095804 GC0XM097484 GC0XM098558 GC0XM099295 GC0XM100329 GC0XM100409 GC0XM090326


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TAF7L Gene:
This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows
testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding
general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms
have been found for this gene. (provided by RefSeq, Dec 2009)

GeneCards Summary for TAF7L Gene:
TAF7L (TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa) is a protein-coding gene. An important paralog of this gene is TAF7.

UniProtKB/Swiss-Prot: TAF7L_HUMAN, Q5H9L4
Function: Probably functions as a spermatogensis-specific component of the DNA-binding general transcription
factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to
various activators and repressors. May play a role in spermatogenesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TAF7L gene promoter:
         TBP   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   FOXO3b   E47   FOXC1   TFIID   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAF7L promoter sequence
   Search Chromatin IP Primers for TAF7L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAF7L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22.1

TAF7L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF7L gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM100523:  view genomic region     (about GC identifiers)

Start:
100,523,241 bp from pter      End:
100,548,059 bp from pter
Size:
24,819 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TAF7L_HUMAN, Q5H9L4 (See protein sequence)
Recommended Name: Transcription initiation factor TFIID subunit 7-like  
Size: 462 amino acids; 52588 Da
Subunit: TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TAF7L may
replace TAF7 in a spermatogenesis-specific form of TFIID. Interacts with TBP; the interaction occurs in a
sub-population of cells (pachytene and haploid round spermatids) and is developmentally regulated through
differential intracellular localization of the two proteins. Interacts with TAF1 (By similarity)
Secondary accessions: Q5H9L6 Q86XI4 Q9BXU5 Q9H5R0
Alternative splicing: 3 isoforms:  Q5H9L4-1   Q5H9L4-2   Q5H9L4-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TAF7L: NX_Q5H9L4

Explore proteomics data for TAF7L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TAF7L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001161946.1  NP_079161.3  

    ENSEMBL proteins: 
     ENSP00000361998   ENSP00000320283   ENSP00000349235   ENSP00000361996  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006751 TAFII55_prot_cons_reg

    Graphical View of Domain Structure for InterPro Entry Q5H9L4

    ProtoNet protein and cluster: Q5H9L4

    1 Blocks protein domain: IPB006751 TAFII55 protein conserved region

    UniProtKB/Swiss-Prot: TAF7L_HUMAN, Q5H9L4
    Similarity: Belongs to the TAF7 family


    Find genes that share domains with TAF7L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TAF7L_HUMAN, Q5H9L4
    Function: Probably functions as a spermatogensis-specific component of the DNA-binding general transcription
    factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to
    various activators and repressors. May play a role in spermatogenesis (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TAF7L           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Taf7l):
     endocrine/exocrine gland  reproductive system 

    Find genes that share phenotypes with TAF7L           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Taf7ltm1.1Jw for TAF7L

       genOway: Develop your customized and physiologically relevant rodent model for TAF7L

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TAF7L (see all 11):
    hsa-miR-4311 hsa-miR-137 hsa-miR-15a hsa-miR-497 hsa-miR-424 hsa-miR-1193 hsa-miR-24 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidTAF7L 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TAF7L_HUMAN, Q5H9L4: Nucleus (By similarity). Cytoplasm (By similarity). Note=Cytoplasmic in spermatogonia and
    early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene
    spermatocytes and round spermatids (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005669transcription factor TFIID complex IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with TAF7L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TAF7L About    
    See pathways by source

    SuperPathContained pathways About
    1Assembly of RNA Polymerase-II Initiation Complex
    Assembly of RNA Polymerase-II Initiation Complex0.91
    Basal transcription factors0.50
    Transcription of mRNA0.91
    Crosstalk Between CARM1 and ESRs0.39
    Protein Acetylation and Deacetylation0.51
    2Apoptotic Pathways in Synovial Fibroblasts
    Nuclear Receptor Activation by Vitamin-A0.57
    3GPCR Pathway
    Estrogen Pathway0.55
    4PEDF Induced Signaling
    Glucocorticoid Receptor Signaling0.43
    5Transcription Ligand Dependent Transcription of Retinoid Target genes
    Transcription Ligand Dependent Transcription of Retinoid Target genes


    Find genes that share SuperPaths with TAF7L           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for TAF7L (see all 7)
        Nuclear Receptor Activation by Vitamin-A
    Protein Acetylation and Deacetylation
    Assembly of RNA Polymerase-II Initiation Complex
    Glucocorticoid Receptor Signaling
    Estrogen Pathway

    1 GeneGo (Thomson Reuters) Pathway for TAF7L
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    1 Kegg Pathway  (Kegg details for TAF7L):
        Basal transcription factors

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAF7L
    Interactions:

        GeneGlobe Interaction Network for TAF7L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TAF7L (Q5H9L43 ENSP000003619984) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TAF1P216753, ENSP000002760724I2D: score=1 STRING: ENSP00000276072
    TBPP202263, ENSP000002303544I2D: score=1 STRING: ENSP00000230354
    TAF13Q155433, ENSP000003550514I2D: score=1 STRING: ENSP00000355051
    TADA3ENSP000003076844STRING: ENSP00000307684
    CPOXENSP000002641934STRING: ENSP00000264193
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006367transcription initiation from RNA polymerase II promoter IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0008150biological_process ND--

    Find genes that share ontologies with TAF7L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for TAF7L



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TAF7L gene (2 alternative transcripts): 
    NM_001168474.1  NM_024885.3  

    Unigene Cluster for TAF7L:

    TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
    Hs.223806  [show with all ESTs]
    Unigene Representative Sequence: NM_024885
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372907(uc004ehc.2 uc004ehb.3) ENST00000324762(uc004eha.3)
    ENST00000356784 ENST00000372905
    miRNA
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    hsa-miR-4311 hsa-miR-137 hsa-miR-15a hsa-miR-497 hsa-miR-424 hsa-miR-1193 hsa-miR-24 hsa-miR-195
    SwitchGear 3'UTR luciferase reporter plasmidTAF7L 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat TAF7L

    Additional mRNA sequence: 

    AF285595.1 AK026810.1 AK308261.1 BC043391.1 

    3 DOTS entries:

    DT.95341214  DT.121312664  DT.95351052 

    23 AceView cDNA sequences:

    AI699474 BC043391 AI190862 AA902216 AW590415 NM_024885 AI220545 AA885108 
    AW236846 AI962851 AW117310 BE504739 AA401416 BX100254 AI950228 AA405087 
    AF285595 AA401392 AK026810 AW183175 AI025202 BF508107 AW235517 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAF7L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTCTAAAGG
    TAF7L Expression
    About this image


    TAF7L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Gonad
             XY Germ Cells Testis Cord
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             XY Germ Cells Testis Cord
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Placenta (Extraembryonic Tissues)
    TAF7L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TAF7L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.223806

    UniProtKB/Swiss-Prot: TAF7L_HUMAN, Q5H9L4
    Tissue specificity: Testis-specific

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TAF7L gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Taf7l1 , 5 TAF7-like RNA polymerase II, TATA box binding protein more1, 5 68.46(n)1
    52.13(a)1
      X (56.18 cM)5
    744691  NM_028958.41  NP_083234.21 
     1344601185 
    fruit fly
    (Drosophila melanogaster)
    Insecta Taf76
    TBP-associated factor 7
    23(a)
    1 → many
    3R(3733055-3735445)
    worm
    (Caenorhabditis elegans)
    Secernentea taf-7.26
    taf-7.16
    Protein TAF-7.1 (taf-7.1) mRNA, complete cds
    29(a)
    26(a)
    many ↔ many
    many ↔ many
    III(12671394-12673423) WBGene00006389
    X(11836197-11837476) WBGene00006388


    ENSEMBL Gene Tree for TAF7L (if available)
    TreeFam Gene Tree for TAF7L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TAF7L gene
    TAF72  
    1 SIMAP similar gene for TAF7L using alignment to 2 protein entries:     TAF7L_HUMAN (see all proteins):
    TAF7

    Find genes that share paralogs with TAF7L           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TAF7L (see all 479)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1466252751,2
    --100489558(+) AGTTAA/CCCTAA 2 -- ds50010--------
    rs1814583781,2
    --100489720(+) GGTAAC/TGAGGG 2 -- ds50010--------
    rs1492237461,2
    --100489770(+) GGCCCA/GAGGGA 2 -- ds50010--------
    rs59667461,2
    C,F,A,H--100489791(+) CCTGCG/CGTCAT 2 -- ds50015Minor allele frequency- C:0.33NS EA NA 397
    rs59672861,2
    C--100489835(+) ACAAAT/CCCCTC 2 -- ds50011Minor allele frequency- C:0.00NA 1
    rs1859988351,2
    --100489939(+) TATGGC/TATTTT 2 -- ds50010--------
    rs1415439911,2
    C--100489960(+) GCCCAA/GATGAA 2 -- ds50010--------
    rs1900610051,2
    --100489974(+) AGATAC/TAGAGC 2 -- ds50010--------
    rs1826940551,2
    --100490132(+) AAAAAA/CCCCAA 2 -- ut310--------
    rs1854713841,2
    --100490134(+) AAAACC/TCAAAC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for TAF7L (100523241 - 100548059 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TAF7L:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv524411CNV Loss19592680

    Human Gene Mutation Database (HGMD): TAF7L
    Locus Specific Mutation Databases (LSDB): TAF7L

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TAF7L
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300314    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TAF7L:
    Male infertility

    Find genes that share disorders with TAF7L           About GenesLikeMe


    Export disorders for TAF7L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TAF7L gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with TAF7L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (Nat. Genet. 2001)
    2. Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure. (PubMed id 17714218)1, 2 Akinloye O.... Simoni M. (Andrologia 2007)
    3. The role of the testis-specific gene hTAF7L in the aetiology of male infertility. (PubMed id 16597641)1, 2 Stouffs K....Liebaers I. (Mol. Hum. Reprod. 2006)
    4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    5. Expression analysis of four testis-specific genes AURKC, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expression pattern. (PubMed id 23292864)1 Yazarloo F....Modarressi M.H. (Med. Oncol. 2013)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (Mol. Cell 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54457 HGNC: 11548 AceView: TAF7L Ensembl:ENSG00000102387 euGenes: HUgn54457
    ECgene: TAF7L Kegg: 54457 H-InvDB: TAF7L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TAF7L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TAF7L gene:
    Search GeneIP for patents involving TAF7L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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