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TAF6L Gene

protein-coding GIFtS: 59

GC11P062295

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
(Previous names: TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ11136 ^²
MGC4288 ^²
PAF65-alpha ^³
PAF65A ^¹, ², ³

Descriptions
PCAF-associated factor 65 alpha ^³
TAF6-like RNA polymerase II ^²
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD ^¹, ²
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa ^²
TAF6-like RNA polymerase II, p300/CBP-associated factor-associated factor, 65kDa ^¹
p300/CBP-associated factor (PCAF)-associated factor 65 ^²

External Ids
HGNC: 17305¹
Entrez Gene: 10629²
UniProtKB: Q9Y6J9³
Ensembl: ENSG00000162227⁷

Search outside databases for aliases for TAF6L gene

Previous GC identifers: GC11P065051 GC11P064114 GC11P062790 GC11P062314

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TAF6L:

Initiation of transcription by RNA polymerase II requires the activities of more than 70

polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID),

which binds to the core promoter to position the polymerase properly, serves as the scaffold for

assembly of the remainder of the transcription complex, and acts as a channel for regulatory

signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily

conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal

transcription, serve as coactivators, function in promoter recognition or modify general

transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This

gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally

similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is

composed of more than 20 polypeptides some of which are TAFs, is required for myogenic

transcription and differentiation. [provided by RefSeq]

UniProtKB/Swiss-Prot: TAF6L_HUMAN, Q9Y6J9

Function: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently

acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human

version of the yeast SAGA complex

Gene Wiki entry for TAF6L

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TAF6L gene

Entrez Gene cytogenetic band: 11q12.3 Ensembl cytogenetic band: 11q12.3 HGNC cytogenetic band: 11q12.3

TAF6L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P062295: (about GC identifiers)

Start:	62,295,451 bp from pter
End:	62,311,390 bp from pter
Size:	15,940 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: TAF6L_HUMAN, Q9Y6J9 (See protein sequence)

Recommended Name: TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa

subunit 6L

Size: 622 amino acids; 67814 Da

Subunit: The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5,

TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as

TADA2L/ADA2, TADA3L/ADA3 and SPT3. Component of the STAGA transcription coactivator-HAT complex,

at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and

TAF9

Subcellular location: Nucleus

Secondary accessions: Q96HA6

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_006464.1

ENSEMBL proteins:

ENSP00000294168

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TAF6L)
	Human Recombinant Proteins from Abnova (TAF6L)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000118	histone deacetylase complex	TAS	9674425
GO:0005634	nucleus	IEA	--

About this table

Antibodies for TAF6L:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for TAF6L
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TAF6L), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TAF6L)
	Novus Biologicals Antibodies for TAF6L

Assays for TAF6L:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9Y6J9

ProtoNet protein and cluster: Q9Y6J9

1 Blocks protein family: IPB011442 Protein of unknown function DUF1546

UniProtKB/Swiss-Prot: TAF6L_HUMAN, Q9Y6J9

Similarity: Belongs to the TAF6 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF6L)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAF6L)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_018336

Applied Biosystems Silencer® siRNAs for TAF6L

Sigma-Aldrich siRNA for TAF6L

Sigma-Aldrich shRNA for TAF6L

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006473
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006473
untagged cDNA clone in CMV expression vector: NM_006473

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006473

UniProtKB/Swiss-Prot: TAF6L_HUMAN, Q9Y6J9

Function: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently

acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human

version of the yeast SAGA complex

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	TAS	9674425
GO:0003702	RNA polymerase II transcription factor activity	IEA	--
GO:0005515	protein binding	IPI	9674425
GO:0016986	transcription initiation factor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for TAF6L (Your Favorite Gene powered by Ingenuity)

Estrogen Receptor Signaling
Glucocorticoid Receptor Signaling

GeneDecks TAF6L for the pathways selected above

About GeneDecksing

5/19 Interacting proteins for TAF6L (ENSP00000294168³ Q9Y6J9^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 19 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TAF9	Q16594¹^,²	STRING (score=.867) EBI-743984, EBI-712521 MINT-2868626 EBI-743984, EBI-712521 MINT-2868626
TAF9	Q16594¹^,²	STRING (score=.867) EBI-743984, EBI-712521 MINT-2868626 EBI-743984, EBI-712521 MINT-2868626
STX11	O75558²	MINT-66418
HDAC2	ENSP00000357621³	STRING (score=.959)
CIR	ENSP00000355034³	STRING (score=.899)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006338	chromatin remodeling	TAS	9674425
GO:0006350	transcription	IEA	--
GO:0006352	transcription initiation	IEA	--
GO:0006357	regulation of transcription from RNA polymerase II promoter	TAS	9674425
GO:0051090	regulation of transcription factor activity	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TAF6L

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF6L)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAF6L)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_018336

Sigma-Aldrich siRNA for TAF6L

Sigma-Aldrich shRNA for TAF6L

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006473

REFSEQ mRNAs for TAF6L gene:

NM_006473.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006473

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006473
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006473
                                 untagged cDNA clone in CMV expression vector: NM_006473

Additional cDNA sequence:

AF069735.1 AK289499.1 AK301145.1 AK310054.1 AK314330.1 BC008785.2

9 DOTS entries:

DT.408270 DT.95082500 DT.208262 DT.120700964 DT.40129632 DT.100754561 DT.92427491 DT.92427502

DT.101975986

24/200 AceView cDNA sequences (see all 200 ):

AI076233 AW772493 AI360158 BM967019 AW303570 AI290982 AA514879 AI224975

AI690272 AI805214 BM727632 BM789539 AW593799 AI400981 AI813433 AA379451

H98053 AI279305 CA489026 AI042217 BQ186037 BM719649 AI936697 AW517218

highest scoring ESTs for TAF6L:

AF069735 AI497781 AI805214 AI826053 AI936697 AW005142 AW005151 AW006342 AW138832 BC008785

Unigene Cluster for TAF6L:

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

Hs.714400 [show with all ESTs]

Unigene Representative Sequence: BC008785

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for TAF6L

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	^	10
SP1:																	-				-								-
SP2:					-
SP3:																					-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for TAF6L

1 Ensembl transcript including schematic representation:

ENST00000294168

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TAF6L expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TAF6L

¹ / ² / ³

10 probe-sets matching TAF6L gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
61870_g_at²^{, 3}	U95-C	1	1.00	1.00	0.32	1.18	AI494617	0.60	1.00	0.82	1
39909_g_at²^{, 3}	U95-A	1	1.00	1.00	0.76	0.56	AF069735	1.00	1.00	1.00	1
39908_at²^{, 3}	U95-A	1	1.00	1.00	0.29	1.07	AF069735	1.00	1.00	1.00	1
49736_g_at²^{, 3}	U95-C	1	1.00	1.00	0.27	1.21	AI497781	1.00	0.90	0.95	1
213209_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BF058726	0.60	1.00	0.82	1
213211_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI005317	0.60	1.00	0.82	1
213210_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI005317	0.60	1.00	0.82	1
213209_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
213211_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
213210_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATCGGCCGTA

SOURCE GeneReport for Unigene cluster: Hs.714400
Expression variation in blood from EXPOLDB for TAF6L

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TAF6L gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TAF6L¹	--	TAF6-like RNA polymerase II, p300/CBP-associated factor more	88.51(n) 94.66(a)	476051 XM_533259.2 XP_533259.2
chimpanzee (Pan troglodytes)	TAF6L¹	--	TAF6-like RNA polymerase II, p300/CBP-associated factor more	99.62(n) 99.84(a)	451264 XM_001142675.1 XP_001142675.1
cow (Bos taurus)	TAF6L¹	--	TAF6-like RNA polymerase II, p300/CBP-associated factor more	88.91(n) 94.18(a)	531109 XM_879600.2 XP_884693.1
rat (Rattus norvegicus)	Taf6l¹	--	TAF6-like RNA polymerase II, p300/CBP-associated factor more	85.44(n) 93.34(a)	309194 XM_219557.4 XP_219557.2
mouse (Mus musculus)	Taf6l^{1, 5}	19⁵	TAF6-like RNA polymerase II, p300/CBP-associated factor more^{1, 5}	85.66(n)¹ 93.51(a)¹	225895¹ NM_146092.1¹ NP_666204.1¹ AK077149⁵ AK144881⁵ (see all 13)

About this table Species with no ortholog for TAF6L

ENSEMBL Gene Tree for TAF6L

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for TAF6L gene

TAF6²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/68 NCBI SNPs in TAF6L are shown (see all 68 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 45)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs11603028^1,2	C,F,H	62295237(+)	`TAAACG/ATGTGT`	1	--	ng5¹ tfbs³		4		EU EA WA	416
	rs11231207^1,2	C,H	62295405(+)	`CCGCCG/TACTGG`	1	--	ng5¹		4		EU EA WA	418
	rs2730031^1,2	H	62295487(-)	`gggggC/Tggtgg`	1	--	ut5¹ ese³		4		EU EA WA	416
--	rs593334^1,2	A	62294423(-)	`TAATCC/GCAGCT`	1	--	ng5¹		0	--	--	--	--
	rs12224551^1,2	H	62306169(+)	`AAATCT/CGTAAG`	1	S/S	syn¹		4		EU EA WA	414
	rs633742^1,2	A,C,F,H,O	62301922(+)	`CTTCCC/TTCAAA`	1	--	int¹		13		MN EA NA EU WA	1238
	rs679626^1,2	A,C,F,H	62297808(+)	`CTTACG/AACTGG`	1	--	int¹		7		EU EA WA NA	562
	rs567791^1,2	A,C,F,H	62300536(+)	`CAGGCT/CACAGA`	1	--	int¹		5		MN EU EA WA	602
	rs11231210^1,2	A,C,F,H	62299756(+)	`GTTGGA/GTCACA`	1	--	int¹		4		EU EA WA	416
	rs11231212^1,2	C,F,H	62301479(+)	`TGTGTT/CCAGAA`	1	--	int¹		4		EU EA WA	418

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HapMap Linkage Disequilibrium images for TAF6L (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602946

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/14 PubMed articles for TAF6L gene (see all 14 ):

Histone-like TAFs within the PCAF histone acetylase complex. (PubMed id 9674425)^{2, 3, 4} Ogryzko V.V.... Nakatani Y. (1998)
Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis. (PubMed id 12601814)^{3, 4} Cavusoglu N....Van Dorsselaer A. (2003)
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. (PubMed id 11564863)^{3, 4} Martinez E....Roeder R.G. (2001)
The TAFs in the HAT. (PubMed id 9674419)^{3, 4} Struhl K. and Moqtaderi Z. (1998)
PKCbetaII augments NF-kappaB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation. (PubMed id 18714023)³ Clarke D.L....Knox A.J. (2008)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)⁴ Matsuoka S.... Elledge S.J. (2007)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)³ Lim J....Zoghbi H.Y. (2006)
Cooperative activation of transcription by autoimmune regulator AIRE and CBP. (PubMed id 15964547)³ Pitkanen J....Peterson P. (2005)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)³ Rual J.F....Vidal M. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)³ Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 10629	HGNC: 17305	AceView: TAF6L	Ensembl:ENSG00000162227	euGenes: HUgn10629
ECgene: TAF6L	H-InvDB: TAF6L

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for TAF6L	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for TAF6L
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for TAF6L:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TAF6L-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TAF6L		Antibodies for TAF6L
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TAF6L		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for TAF6L

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TAF6L Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for TAF6L

Summaries
for TAF6L

Genomic Location
for TAF6L

Proteins
for TAF6L

Protein Domains/
Families
for TAF6L

Gene Function
for TAF6L

Pathways & Interactions
for TAF6L

Drugs & Compounds
for TAF6L

Transcripts
for TAF6L

Expression
for TAF6L

Orthologs
for TAF6L

Paralogs
for TAF6L

SNPs/Variants
for TAF6L

Disorders & Mutations
for TAF6L

Medical News
for TAF6L

Publications
for TAF6L

Search for TAF6L

Genome Databases showing TAF6L

Other Databases showing TAF6L

Specialized Databases showing TAF6L

Licensable Technologies
for TAF6L

Services
for TAF6L

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TAF6L Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor TAF6L

Summariesfor TAF6L

Genomic Locationfor TAF6L

Proteinsfor TAF6L

Protein Domains/Familiesfor TAF6L

Gene Functionfor TAF6L

Pathways & Interactionsfor TAF6L

Drugs & Compoundsfor TAF6L

Transcriptsfor TAF6L

Expression for TAF6L

Orthologsfor TAF6L

Paralogsfor TAF6L

SNPs/Variantsfor TAF6L

Disorders & Mutationsfor TAF6L

Medical Newsfor TAF6L

Publicationsfor TAF6L

Search for TAF6L

Genome Databases showing TAF6L

Other Databases showing TAF6L

Specialized Databases showing TAF6L

Licensable Technologiesfor TAF6L

Servicesfor TAF6L

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TAF6L

Summaries
for TAF6L

Genomic Location
for TAF6L

Proteins
for TAF6L

Protein Domains/
Families
for TAF6L

Gene Function
for TAF6L

Pathways & Interactions
for TAF6L

Drugs & Compounds
for TAF6L

Transcripts
for TAF6L

Expression
for TAF6L

Orthologs
for TAF6L

Paralogs
for TAF6L

SNPs/Variants
for TAF6L

Disorders & Mutations
for TAF6L

Medical News
for TAF6L

Publications
for TAF6L

Licensable Technologies
for TAF6L

Services
for TAF6L