TAF6 Gene
protein-coding GIFtS: 62
GCID: GC07M099704
|
|
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated...(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
(Previous symbol: TAF2E)
| |
Aliases
for TAF6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor,80kDa1 2 | | TAF(II)702 3 | | TAF2E1 2 3 5 | | TAF(II)802 3 | | TAFII801 2 3 5 | | TAFII-702 3 | | TAFII701 2 3 | | TAFII-802 3 | | MGC:89641 2 | | RNA Polymerase II TBP-Associated Factor Subunit E2 3 | | TAFII851 2 | | Transcription Initiation Factor TFIID Subunit 62 | | TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, E, 70/85kD1 2 | | Transcription Initiation Factor TFIID 80 KDa Subunit3 | | Transcription Initiation Factor TFIID 70 KDa Subunit2 3 | | |
| External Ids: | HGNC: 115401 | Entrez Gene: 68782 | Ensembl: ENSG000001062907 | OMIM: 6029555 | UniProtKB: P498483 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n409395 n337262 | |
Export aliases for TAF6 gene to outside databasesPrevious GC identifers: GC07M098239 GC07M099302 GC07M099316 GC07M099351 GC07M099542 GC07M094340
Summaries
for TAF6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TAF6:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position thepolymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as achannel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarilyconserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve ascoactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complexassembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBPbut strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants.(provided by RefSeq, Jun 2010)
UniProtKB/Swiss-Prot: TAF6_HUMAN, P49848Function: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex andTBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoterresponses to various activators and repressors
Gene Wiki entry for TAF6
|
Genomic Views
for TAF6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TAF6 gene promoter:
NRSF form 1 NRSF form 2 Tal-1beta HNF-1A Arnt E47 CREB FAC1 HNF-1 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for TAF6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7qTAF6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M099704: view genomic region
(about GC identifiers)
Start:
|
99,704,693 bp from pter |
End:
|
99,717,481 bp from pter |
Size:
|
12,789 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 99,064,811-99,077,600 |
ORGUL member locations:
Legend (see complete legend)
99704692 99710844 99716995 chr7
|
Proteins
for TAF6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TAF6_HUMAN, P49848 (See
protein sequence)Recommended Name: Transcription initiation factor TFIID subunit 6 Size: 677 amino acids; 72668 Da
Subunit: TFIID and PCAF are composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TBPis not part of TFTC. Interacts directly with TBP, TAF1/TAFII250, TAF9/TAFII31 AND TAF12/TAFII20. TheTAF6/TAFII70-TAF9/TAFII31 heterodimer forms an octamer complex with the TAF4B/TFII105-TAF12/TFIID20 heterodimer.Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5,as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF,PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Also interactswith the GTFs, TFIIEalpha/GTF2E1 and TFIIFalpha/GTF2F1. Component of the TFTC-HAT complex
Subcellular location: Nucleus
Secondary accessions: A4D2B2 A4D2B3 B4DT11 D6W5U2 Q6AI29Alternative splicing: 3 isoforms: P49848-1 P49848-2 P49848-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TAF6: NX_P49848
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49848
TAF6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001177344.1 NP_005632.1 NP_647476.1
ENSEMBL proteins: ENSP00000413614 ENSP00000389575 ENSP00000419760 ENSP00000416396 ENSP00000344537 ENSP00000399982 ENSP00000419555 ENSP00000410012 ENSP00000412346 ENSP00000428639 ENSP00000390073 ENSP00000428071 ENSP00000406315 ENSP00000390220 ENSP00000395627 ENSP00000427710 ENSP00000407980 Reactome Protein details: P49848
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
TAF6 for ontologies About GeneDecksing
TAF6 Antibody Products:
Assay Products for TAF6: |
Protein
Domains /
Families
for TAF6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TAF6 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49848ProtoNet protein and cluster: P49848 2 Blocks protein families: IPB004823 TATA box binding protein associated factor (TAF) IPB011442 Protein of unknown function DUF1546
UniProtKB/Swiss-Prot: TAF6_HUMAN, P49848Similarity: Belongs to the TAF6 family |
Function
for TAF6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TAF6_HUMAN, P49848Function: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex andTBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoterresponses to various activators and repressors
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for TAF6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF6 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
TAF6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TAF6:
|
Pathways & Interactions
for TAF6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of RNA Pol II elongation complex | | | 2 | Assembly of RNA Polymerase-II Initiation Complex | | | 3 | HIV Infection | | | 4 | Late Phase of HIV Life Cycle | | | 5 | Transcription | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for TAF6
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TAF6 (see all 7)
1  GeneGo (Thomson Reuters) Pathway for TAF6
1  BioSystems Pathway for TAF6
5/19 
Reactome Pathways for TAF6 (see all 19)
1 
Kegg Pathway (Kegg details for TAF6):
TAF6 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TAF6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/224 Interacting proteins for TAF6 (P498482, 3 ENSP000003445374) via UniProtKB, MINT, STRING, and/or I2D (see all 224)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006352 | DNA-dependent transcription, initiation |
IDA | 9603525 | | GO:0006355 | regulation of transcription, DNA-dependent |
IDA | 15328371 | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0006368 | transcription elongation from RNA polymerase II promoter |
TAS | -- |
TAF6 for ontologies About GeneDecksing
|
Drugs & Compounds
for TAF6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TAF6
Search CenterWatch for drugs/clinical trials and news about TAF6
|
Transcripts
for TAF6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TAF6 gene (5 alternative transcripts): NM_001190415.1 NM_005641.3 NM_139315.2 NM_139122.1 NM_139123.1 Unigene Cluster for TAF6: TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa Hs.489309 [show with all ESTs]Unigene Representative Sequence: NM_00564118/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000421980 ENST00000453269(uc003utg.3 uc003uti.3 uc003utk.3)
ENST00000472509(uc003uth.3) ENST00000452041 ENST00000344095(uc003utm.3)
ENST00000437822(uc011kji.2) ENST00000487115 ENST00000487288 ENST00000493322
ENST00000440225 ENST00000452438 ENST00000523306 ENST00000449571 ENST00000520135
ENST00000451699 ENST00000417349 ENST00000431404 ENST00000460673
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): TAF6 (NM_139315) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TAF6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF6 |
Additional cDNA sequence: AK097781.1 AK300005.1 AK314428.1 AK315077.1 BC018115.1 BC127819.1 CR627390.1 L25444.1 NR_033792.1 U31659.1 24/28 DOTS entries (see all 28): DT.450124 DT.100723809 DT.92468297 DT.100044202 DT.100645712 DT.100723786 DT.100767792 DT.100059866 DT.100723768 DT.100723802 DT.100723777 DT.97774211 DT.100059865 DT.100723773 DT.40255906 DT.95273993 DT.100876224 DT.121080631 DT.92468307 DT.100051569 DT.121080669 DT.121080706 DT.92468322 DT.92468328 24/175 AceView cDNA sequences (see all 175): NM_139122 F01478 CF243183 NM_005641 BQ223742 BM458212 BU169243 BM553684 BM557210 F01487 NM_139315 BU184274 BG258813 F02888 CD636888 BQ072075 BQ440506 U31659 BU508273 AU124861 AK097781 BM806299 CR624352 BX396535
GeneLoc Exon Structure
5/20 Alternative Splicing Database (ASD) splice patterns (SP) for TAF6 (see all 20) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | |
| ExUns: | 11d | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for TAF6
|
Expression
for TAF6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TAF6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCACTTTCTT
About this image
See TAF6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TAF6
SOURCE GeneReport for Unigene cluster: Hs.489309
SABiosciences Custom PCR Arrays for TAF6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TAF6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAF6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF6 |
Orthologs
for TAF6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TAF6 gene from 7/28 species (see all 28) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Taf61 , 5 |
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated more1, 5 |
87.33(n)1
97.78(a)1 |
|
5 (76.98 cM)5
213431 NM_009315.31 NP_033341.11
1381786175 |
African clawed frog
(Xenopus laevis) |
Amphibia |
LOC3977242 |
TFIID subunit |
74.58(n) |
|
D50054.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb83e082 |
Transcribed sequence with weak similarity to protein more |
73.96(n) |
|
CK024464.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Taf61 , 3 |
transcription initiation from Pol II
promoter more3
TBP-associated factor 61 |
48(a)3
57.8(n)1
50.27(a)1 |
|
3 76B93
401341 NM_079437.31 NP_524161.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
taf-6.11 |
Protein TAF-6.1 |
40.89(n)
27.84(a) |
|
173498 NM_061518.4 NP_493919.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATTAF66TAF6B6 |
TBP-associated factor 6B |
32(a)26(a) |
many ↔ manymany ↔ many |
1(1403085-1407501) 1(20290556-20293324) |
rice
(Oryza sativa) |
Liliopsida |
-- |
TATA binding protein-associated factor, putative, ... |
31(a) |
1 → many |
1(17959819-17967556) |
ENSEMBL Gene Tree for TAF6 (if available)
TreeFam Gene Tree for TAF6 (if available) |
Paralogs
for TAF6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TAF6 gene
- TAF6L2
1 SIMAP similar gene for TAF6 using alignment to 15 protein entries: TAF6_HUMAN (see all proteins):TAF6L
TAF6 for paralogs About GeneDecksing
|
Genomic Variants
for TAF6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TAF6 (99704693 - 99717481 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TAF6
1 CNV: 2104 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAF6 |
|
Disorders
/ Diseases
for TAF6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TAF6 for disorders About GeneDecksing
OMIM gene information: 602955
OMIM disorders: --
3  diseases for TAF6: About MalaCardsmaturity-onset diabetes of the young bare lymphocyte syndrome immunodeficiency
1 disease from the University of Copenhagen DISEASES database for TAF6:maturity-onset diabetes of the young Export disorders for TAF6 gene to outside databases
|
Publications
for TAF6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TAF6 gene, integrated from 9 sources (see all 78):
(articles sorted by number of sources associating them with TAF6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. (PubMed id 7667268)1, 2, 9 Hisatake K.... Roeder R.G. (1995)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Core promoter binding by histone-like TAF complexes. (PubMed id 15601843)1, 2 Shao H.... Dikstein R. (2005)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one- dimensional gel electrophoresis. (PubMed id 12601814)1, 2 Cavusoglu N.... van Dorsselaer A. (2003)
- Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID. (PubMed id 8262073)1, 2 Weinzierl R.O.... Tjian R. (1993)
- Discussion paper: experimental and clinical immunopharmacology data applicable to cancer immunotherapy. (PubMed id 826207)1, 3 Mathe G....Simmler M.C. (1976)
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External Searches for TAF6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing TAF6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing TAF6 gene
(According to HUGE)
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Specialized Databases showing TAF6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for TAF6 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/taf6/ |
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| Patent Information for TAF6 gene:
Search GeneIP for patents involving TAF6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for TAF6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TAF6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAF6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF6 | | | OriGene Protein Over-expression Lysate for TAF6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TAF6 | | OriGene 3'-UTR Clone for TAF6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TAF6 | | OriGene Custom Protein Services for TAF6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TAF6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAF6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAF6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAF6 |
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| | | | Search Tocris compounds for TAF6 |
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 | | | TAF6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF6 |
|  |  |  | | | | Search ThermoFisher Antibodies for TAF6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF6 |
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