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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TAF4B Gene

protein-coding GIFtS: 57
GCID: GC18P023806

TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated...

(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
(Previous symbol: TAF2C2)

Explore 1 disease affiliated with
TAF4B via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
TAF4b RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 105kDa¹ ²		TAF(II)105² ³
TAF2C2¹ ² ³ ⁵		TAFII-105² ³
TAFII105¹ ² ³ ⁵		TATA Box Binding Protein (TBP)-Associated Factor 4B²
TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, C2, 105kD¹ ²		Transcription Initiation Factor TFIID 105 KD Subunit²
Transcription Initiation Factor TFIID 105 KDa Subunit² ³		Transcription Initiation Factor TFIID Subunit 4B²

External Ids:	HGNC: 11538¹	Entrez Gene: 6875²	Ensembl: ENSG00000141384⁷	OMIM: 601689⁵	UniProtKB: Q92750³

Export aliases for TAF4B gene to outside databases

Previous GC identifers: GC18P023722 GC18P023538 GC18P022037 GC18P022039 GC18P020657

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAF4B:

TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex,

which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific

TAF that may be responsible for mediating transcription by a subset of activators in B cells. (provided by RefSeq, Sep

2011)

UniProtKB/Swiss-Prot: TAF4B_HUMAN, Q92750

Function: Cell type-specific subunit of TFIID that may function as a gene-selective coactivator in certain cells. TFIID

is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and

repressors. TAFII105 is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation

of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through

interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription

Gene Wiki entry for TAF4B

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_010966.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TAF4B gene promoter:
Elk-1 Pax-5 HNF-4alpha2 IRF-1 HNF-4alpha1 HNF-1A Max AREB6 HNF-1 c-Myc
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for TAF4B

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF4B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11.2 Ensembl cytogenetic band: 18q11.2 HGNC cytogenetic band: 18q11.1

TAF4B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF4B gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18P023806: view genomic region (about GC identifiers)

Start:	23,805,900 bp from pter	End:	23,971,649 bp from pter
Size:	165,750 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TAF4B_HUMAN, Q92750 (See protein sequence)

Recommended Name: Transcription initiation factor TFIID subunit 4B

Size: 862 amino acids; 91091 Da

Subunit: TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Heterodimerizes

with TAF12/TFII20 via the C-terminal H2A-like histone-fold domain. This heterodimer forms a histone-like octamer with

the TAF6/TAFII70-TAF9/TAFII31 heterodimer. Interacts with P65/RELA homodimers and P65/RELA-REL heterodimers.

Interaction with POU2AF1, via its C-terminal activation domain, is required for octamer-dependent transcription

Subcellular location: Nucleus. Cytoplasm. Note=Export into the cytoplasm is mediated by a CRM1-independent nuclear

export pathway and not by phosphorylation

Secondary accessions: Q29YA4 Q29YA5

Alternative splicing: 2 isoforms: Q92750-1 Q92750-2 (May be due to exon inclusion. No experimental confirmation available. Unphosphorylated form)

Explore the universe of human proteins at neXtProt for TAF4B: NX_Q92750

Post-translational modifications:

Under stimulation by forskolin, Isoform 1 is phosphorylated by protein kinase A (PKA)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q92750

TAF4B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_005631.1

ENSEMBL proteins:

ENSP00000269142 ENSP00000462980 ENSP00000389365 ENSP00000383314

Reactome Protein details: Q92750
Human Recombinant Protein Products for TAF4B:

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	Uscn Proteins for TAF4B

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	--
GO:0005654	nucleoplasm	TAS	--
GO:0005669	transcription factor TFIID complex	IEA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IEA	--

TAF4B for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TAF4B for domains About GeneDecksing

3 InterPro domains/families:

IPR007900 TAF4

IPR003894 TAFH_NHR1

IPR009072 Histone-fold

Graphical View of Domain Structure for InterPro Entry Q92750

ProtoNet protein and cluster: Q92750

2 Blocks protein families:

IPB003894 TAF-like region

IPB007900 Transcription initiation factor TFIID component TAF4

UniProtKB/Swiss-Prot: TAF4B_HUMAN, Q92750

Similarity: Belongs to the TAF4 family

Similarity: Contains 1 histone-fold domain

Similarity: Contains 1 TAFH (NHR1) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: TAF4B_HUMAN, Q92750

Function: Cell type-specific subunit of TFIID that may function as a gene-selective coactivator in certain cells. TFIID

is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and

repressors. TAFII105 is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation

of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through

interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IDA	15601843
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0046982	protein heterodimerization activity	IEA	--
GO:0051059	NF-kappaB binding	IPI	10849440

TAF4B for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for TAF4B:

Decreased viability

5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Taf4b):

cellular

endocrine/exocrine gland

homeostasis/metabolism

mortality/aging

reproductive system

TAF4B for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Taf4b^tm1Rtj for TAF4B

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TAF4B

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		hsa-miR-2052 hsa-miR-3607-3p hsa-miR-300 hsa-miR-374a hsa-miR-30d hsa-miR-301a hsa-miR-449a hsa-miR-30a

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF4B

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Formation of RNA Pol II elongation complex

8/12 pathways (see all 12)
RNA Polymerase II Pre-transcription Events	0.72	Addition of the third nucleotide on the nascent transcript	0.40
Transcription of the HIV genome	0.70	RNA Polymerase II Promoter Escape	0.40
RNA Polymerase II Transcription Initiation And Promoter Clearance	0.40	RNA Polymerase II Transcription Initiation	0.40
HIV-1 Transcription Initiation	0.40	Addition of the fourth nucleotide on the Nascent Transcript: Second Transition	0.40

HIV Infection

	HIV Infection	1.00			Transcription Ligand-Dependent Transcription of Retinoid-Target genes	0.28
	Transcription_Ligand-Dependent Transcription of Retinoid-Target genes	0.28

Late Phase of HIV Life Cycle

Late Phase of HIV Life Cycle

1.00

HIV Life Cycle

0.90

Transcription

Transcription

1.00

RNA Polymerase II Transcription

0.69

Disease

Disease

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for TAF4B

Transcription Ligand-Dependent Transcription of Retinoid-Target genes

1 GeneGo (Thomson Reuters) Pathway for TAF4B

Transcription Ligand-Dependent Transcription of Retinoid-Target genes

1 BioSystems Pathway for TAF4B

Validated targets of C-MYC transcriptional activation

5/19 Reactome Pathways for TAF4B (see all 19)

	Late Phase of HIV Life Cycle
	RNA Polymerase II Transcription
	RNA Polymerase II Transcription Initiation And Promoter Clearance
	Disease
	HIV Infection

2 Kegg Pathways (Kegg details for TAF4B):

	Basal transcription factors
	Huntington's disease

TAF4B for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for TAF4B

STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

5/23 Interacting proteins for TAF4B (Q92750³ ENSP00000269142⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GTF2A1	P52655³, ENSP00000298173⁴	I2D: score=1 STRING: ENSP00000298173
TAF1	P21675³, ENSP00000276072⁴	I2D: score=1 STRING: ENSP00000276072
TBP	P20226³, ENSP00000230354⁴	I2D: score=1 STRING: ENSP00000230354
TAF12	Q16514³, ENSP00000263974⁴	I2D: score=2 STRING: ENSP00000263974
RELA	Q04206³, ENSP00000384273⁴	I2D: score=2 STRING: ENSP00000384273

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006352	DNA-dependent transcription, initiation	NAS	--
GO:0006355	regulation of transcription, DNA-dependent	NAS	--
GO:0006366	transcription from RNA polymerase II promoter	TAS	--
GO:0006367	transcription initiation from RNA polymerase II promoter	TAS	--
GO:0006368	transcription elongation from RNA polymerase II promoter	TAS	--

TAF4B for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TAF4B
Search CenterWatch for drugs/clinical trials and news about TAF4B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TAF4B gene:

NM_005640.1

Unigene Cluster for TAF4B:

TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa

Hs.369519 [show with all ESTs]

Unigene Representative Sequence: NM_005640

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000269142(uc002kvu.4 uc002kvs.4 uc002kvt.4) ENST00000578121

ENST00000418698 ENST00000400466

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		hsa-miR-2052 hsa-miR-3607-3p hsa-miR-300 hsa-miR-374a hsa-miR-30d hsa-miR-301a hsa-miR-449a hsa-miR-30a

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Additional cDNA sequence:

AB234096.1 AK302593.1 AY888048.1 BC016360.1 BC032791.1 Y09321.1

3 DOTS entries:

DT.442127 DT.101966187 DT.92420195

24/41 AceView cDNA sequences (see all 41):

AA287145 AA412656 BX952116 BX952140 AA721195 AA458814 BC016360 AA287057

BM973282 AA976562 AA825151 AI366784 BC032791 AA252510 Y09321 BQ012407

AA252384 R24013 W77893 BI517527 BG213757 W72761 BM853763 AW297262

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TAF4B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGCACATT

About this image

TAF4B expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Testis

Seminiferous Tubules

Spermatogonial Stem Cells

Selective marker (cell-identifying gene)

Germ Cells, Male Gametocytes

Ovary

Germ Cells, Male Gametocytes

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TAF4B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TAF4B

SOURCE GeneReport for Unigene cluster: Hs.369519

UniProtKB/Swiss-Prot: TAF4B_HUMAN, Q92750

Tissue specificity: Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells

SABiosciences Custom PCR Arrays for TAF4B

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF4B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for TAF4B gene from 7/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TAF4B¹	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated more	69.22(n) 64.02(a)		421086 XM_419170.3 XP_419170.3
lizard (Anolis carolinensis)	Reptilia	TAF4B⁶	--	49(a)	1 ↔ 1	4(36732218-36789537)
zebrafish (Danio rerio)	Actinopterygii	taf4b⁶ CU627988.1⁶	--	35(a) 10(a)	1 ↔ 1 possible ortholog	20(18306330-18342154) 13(52365693-52389750)
fruit fly (Drosophila melanogaster)	Insecta	Taf4³	regulation of transcription, DNA-dependent general more	47(a)		--
worm (Caenorhabditis elegans)	Secernentea	taf-4⁶	TAF (TBP-associated transcription factor) family m...	19(a)	possible ortholog	I(382836-388850)
thale cress (Arabidopsis thaliana)	eudicotyledons	TAF4B⁶ TAF4⁶	TBP-associated factor 4	13(a) 10(a)	many ↔ many many ↔ many	1(9643351-9647376) 5(17315449-17321185)
rice (Oryza sativa)	Liliopsida	-- --	transcription initiation factor, putative, express... transcription initiation factor, putative, express...	14(a) 13(a)	many ↔ many many ↔ many	2(26390084-26397394) 3(18637302-18646389)

ENSEMBL Gene Tree for TAF4B (if available)
TreeFam Gene Tree for TAF4B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TAF4B gene

TAF4²

2 SIMAP similar genes for TAF4B using alignment to 3 protein entries: TAF4B_HUMAN (see all proteins):

taf4b TAF4

TAF4B for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for TAF4B
PGOHUM00000246038

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144763013^1,2		--	23804503(+)	`AGTTTC/TTAAGT`	1	--	us2k¹		0	--	--	--	--
rs148540601^1,2		--	23804542(+)	`AATGCA/GTCTCT`	1	--	us2k¹		0	--	--	--	--
rs9946386^1,2	C	--	23804568(+)	`AGGAGG/ATGCTC`	1	--	us2k¹		2		WA	120
rs75412265^1,2	C	--	23804578(+)	`CAATAA/CATTGA`	1	--	us2k¹		2		WA	120
rs57851015^1,2	F	--	23804580(+)	`ATAAAT/GTGAGT`	1	--	us2k¹		1		WA	118
rs116119889^1,2	F	--	23804584(+)	`ATTGAG/ATTTTT`	1	--	us2k¹		1		WA	118
rs75201353^1,2		--	23804599(+)	`CCCCAA/GCTCCA`	1	--	us2k¹		1		EA	120
rs193292503^1,2		--	23804637(+)	`GATCAA/GGGAAT`	1	--	us2k¹		0	--	--	--	--
rs183845264^1,2		--	23804723(+)	`AGGTAA/GTAAGT`	1	--	us2k¹		0	--	--	--	--
rs141876045^1,2		--	23804884(+)	`AGCTTA/GTAAAA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TAF4B (23805900 - 23971649 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TAF4B
1 CNV: 102615

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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TAF4B for disorders           About GeneDecksing

OMIM gene information: 601689    OMIM disorders: --

1 disease for TAF4B:    About MalaCards

huntington's disease

Human Genome Epidemiology (HuGE) Navigator: TAF4B (1 document)

Export disorders for TAF4B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TAF4B gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with TAF4B)

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Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes. (PubMed id 10849440)^{1, 2, 3} Yamit-Hezi A.... Dikstein R. (2000)
Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130. (PubMed id 8858156)^{1, 2, 3} Dikstein R.... Tjian R. (1996)
A composite nuclear export signal in the TBP-associated factor TAFII105. (PubMed id 11567023)^{1, 2, 9} Rashevsky-Finkel A.... Dikstein R. (2001)
Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa cell line. (PubMed id 16088961)^{1, 2, 9} Wu Y.... Li R. (2005)
Specific interaction of TAFII105 with OCA-B is involved in activation of octamer-dependent transcription. (PubMed id 10828057)^{1, 2, 9} Wolstein O.... Dikstein R. (2000)
Core promoter binding by histone-like TAF complexes. (PubMed id 15601843)^{1, 2} Shao H.... Dikstein R. (2005)
TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes. (PubMed id 19635797)^{1, 9} Gazit K....Dikstein R. (2009)
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)¹ Fox C.S....Borecki I.B. (2012)
TAF4b and Jun/activating protein-1 collaborate to reg ulate the expression of integrin alpha6 and cancer cell migration properties. (PubMed id 20353996)¹ Kalogeropoulou M....Pintzas A. (2010)
Genome-wide association study in premature ovarian fa ilure patients suggests ADAMTS19 as a possible candidate gene. (PubMed id 19508998)¹ Knauff E.A....Fauser B.C. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 6875	HGNC: 11538	AceView: TAF4B	Ensembl:ENSG00000141384	euGenes: HUgn6875
ECgene: TAF4B	Kegg: 6875	H-InvDB: TAF4B

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TAF4B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TAF4B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TAF4B gene:
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