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TAF3 Gene

protein-coding   GIFtS: 56
GCID: GC10P007860

TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated...

(Previous names: TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated
Factor, 140kDa1 2
     TAFII-1402 3
TAFII1402 3 5     TBP-Associated Factor 32 3
Transcription Initiation Factor TFIID 140 KDa Subunit2 3     TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor,
140 KD1
140 KDa TATA Box-Binding Protein-Associated Factor2 3     RNA Polymerase II Transcription Factor TAFII1402
TAF(II)1402 3     Transcription Initiation Factor TFIID Subunit 32
TAF1402 3     

External Ids:    HGNC: 173031   Entrez Gene: 838602   Ensembl: ENSG000001656327   OMIM: 6065765   UniProtKB: Q5VWG93   

Export aliases for TAF3 gene to outside databases

Previous GC identifers: GC10P007805 GC10M007824 GC10P008010 GC10P007864 GC10P007898


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TAF3 Gene:
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA
box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute
to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 (PubMed
11438666)).(supplied by OMIM, May 2009)

GeneCards Summary for TAF3 Gene:
TAF3 (TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa) is a protein-coding gene. Diseases associated with TAF3 include herpes simplex, and myocardial infarction. GO annotations related to this gene include p53 binding.

UniProtKB/Swiss-Prot: TAF3_HUMAN, Q5VWG9
Function: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation
by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter
responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of
myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the
differentiation process

Gene Wiki entry for TAF3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_008705.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TAF3 gene promoter:
         HOXA9   HOXA9B   TBP   ATF-2   Meis-1b   PPAR-gamma1   TFIID   PPAR-gamma2   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TAF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p15.1   Ensembl cytogenetic band:  10p14   HGNC cytogenetic band: 10p15.1

TAF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P007860:  view genomic region     (about GC identifiers)

Start:
7,860,467 bp from pter      End:
8,058,590 bp from pter
Size:
198,124 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TAF3_HUMAN, Q5VWG9 (See protein sequence)
Recommended Name: Transcription initiation factor TFIID subunit 3  
Size: 929 amino acids; 103582 Da
Subunit: Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of
TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and
GCN5L2. Interacts with TBPL2
Sequence caution: Sequence=AAH45106.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAH62352.1; Type=Erroneous initiation; Sequence=AAH73884.1; Type=Erroneous initiation;
Secondary accessions: Q05DA0 Q6GMS5 Q6P6B5 Q86VY6 Q9BQS9 Q9UFI8

Explore the universe of human proteins at neXtProt for TAF3: NX_Q5VWG9

Explore proteomics data for TAF3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TAF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114129.1  
    ENSEMBL proteins: 
     ENSP00000340271  

    TAF3 Human Recombinant Protein Products:

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    TAF3 Assay Products:

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    Cloud-Clone Corp. CLIAs for TAF3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PHF: Zinc fingers, PHD-type

    Selected InterPro protein domains (see all 6):
     IPR019786 Zinc_finger_PHD-type_CS
     IPR001965 Znf_PHD
     IPR006565 BTP
     IPR013083 Znf_RING/FYVE/PHD
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q5VWG9

    ProtoNet protein and cluster: Q5VWG9

    1 Blocks protein domain: IPB001965 Zn-finger-like

    UniProtKB/Swiss-Prot: TAF3_HUMAN, Q5VWG9
    Domain: The PHD-type zinc finger mediates binding to histone H3 methyllysine at position 4 (H3K4me3) (By
    similarity)
    Similarity: Belongs to the TAF3 family
    Similarity: Contains 1 PHD-type zinc finger


    TAF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TAF3_HUMAN, Q5VWG9
    Function: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation
    by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter
    responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of
    myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the
    differentiation process

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002039p53 binding IEA--
    GO:0005515protein binding IPI11438666
    GO:0008270zinc ion binding IEA--
    GO:0046982protein heterodimerization activity ----
         
    TAF3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TAF3:
     Increased Salmonella enterica   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TAF3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TAF3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TAF3

    miRNA
    Products:
        
    miRTarBase miRNAs that target TAF3:
    hsa-mir-1180-3p (MIRT035927), hsa-mir-375 (MIRT019668)

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    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF3

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TAF3_HUMAN, Q5VWG9: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    mitochondrion2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15870280
    GO:0005669transcription factor TFIID complex IDA11438666

    TAF3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TAF3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Assembly of RNA Polymerase-II Initiation Complex
    Basal transcription factors0.50
    2Influenza A
    Herpes simplex infection0.33
    3Transcription Ligand Dependent Transcription of Retinoid Target genes
    Transcription Ligand Dependent Transcription of Retinoid Target genes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for TAF3
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    2 Kegg Pathways  (Kegg details for TAF3):
        Basal transcription factors
    Herpes simplex infection


    TAF3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAF3
    Interactions:

        GeneGlobe Interaction Network for TAF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TAF3 (Q5VWG91, 2, 3 ENSP000003402714) via UniProtKB, MINT, STRING, and/or I2D (see all 78)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    H3F3BP842431, 2, 3EBI-1560087,EBI-120658 MINT-8088958 MINT-8088885 MINT-8088919 I2D: score=1 
    TAF5Q155422, 3, ENSP000003588544MINT-8089065 I2D: score=1 STRING: ENSP00000358854
    H3F3AP842431, 2, 3, ENSP000003557784EBI-1560087,EBI-120658 MINT-8088958 MINT-8088885 MINT-8088919 I2D: score=1 STRING: ENSP00000355778
    TBPP202263, ENSP000002303544I2D: score=2 STRING: ENSP00000230354
    TBPL2Q6SJ963, ENSP000002472194I2D: score=2 STRING: ENSP00000247219
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA18549481
    GO:0006351transcription, DNA-templated IEA--
    GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity IDA18549481
    GO:0051457maintenance of protein location in nucleus IDA15870280

    TAF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TAF3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TAF3 gene: 
    NM_031923.3  

    Unigene Cluster for TAF3:

    TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
    Hs.527688  [show with all ESTs]
    Unigene Representative Sequence: NM_031923
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000344293(uc010qbd.2)
    miRNA
    Products:
         
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    Inhib. RNA
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TAF3 (NM_031923)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF3
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TAF3
      QuantiTect SYBR Green Assays in human, mouse, rat TAF3
      QuantiFast Probe-based Assays in human, mouse, rat TAF3

    Additional mRNA sequence: 

    AJ292190.1 AK307521.1 AK307657.1 AL117661.1 BC017320.1 BC024661.1 BC028077.1 BC045106.1 
    BC062352.1 BC073884.1 BC105593.1 

    3 DOTS entries:

    DT.208158  DT.97836827  DT.202254 

    Selected AceView cDNA sequences (see all 74):

    AI218666 BQ027547 AI363141 AL117661 AA933921 AI554630 BC045106 CD672928 
    AA910049 AA927947 AI554695 BM704312 BF513064 BC073884 AI570472 BC017320 
    CA397451 BX094325 AA827118 AW005174 AI002323 AJ292190 AI123516 AI364321 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAF3 expression in normal human tissues (normalized intensities)      TAF3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTGCACCCC
    TAF3 Expression
    About this image


    TAF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)
             Telencephalon
    TAF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TAF3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.527688
        Custom PCR Arrays for TAF3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TAF3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Taf31 , 5 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated more1, 5 83.39(n)1
    85.29(a)1
      2 (6.74 cM)5
    2093611  NM_027748.31  NP_082024.21 
     99145525 
    chicken
    (Gallus gallus)
    Aves TAF31 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated more 75.59(n)
    78.29(a)
      419107  NM_001030841.2  NP_001026012.1 
    lizard
    (Anolis carolinensis)
    Reptilia TAF36
    TAF3 RNA polymerase II, TATA box binding protein (...
    78(a)
    1 ↔ 1
    5(75650-175999)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.139762 Xenopus laevis transcribed sequence with weak similarity more 82.11(n)    CA789851.1 
    zebrafish
    (Danio rerio)
    Actinopterygii taf36
    TAF3 RNA polymerase II, TATA box binding protein (...
    52(a)
    1 ↔ 1
    4(24171361-24255591) ENSDARG00000045513
    fruit fly
    (Drosophila melanogaster)
    Insecta bip26
    bip2
    17(a)
    1 ↔ 1
    4(480508-487450)
    worm
    (Caenorhabditis elegans)
    Secernentea taf-36
    Protein TAF-3, isoform a
    20(a)
    1 ↔ 1
    X(16332440-16346023) WBGene00006384


    ENSEMBL Gene Tree for TAF3 (if available)
    TreeFam Gene Tree for TAF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TAF3 (see all 3969)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3710680191,2
    C--7813910(+) TCTTT-/TTTTTT 1 -- int10--------
    rs344319351,2
    C--7819138(+) GCGCC-/G/GCG 
            
    TGCAT
    2 -- int1 cds10--------
    rs1870676391,2
    --7858599(+) CTCCAC/GCTTCT 1 -- us2k10--------
    rs773308441,2
    F--7858673(+) CACTCC/GTTCCC 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs1476040881,2
    --7858702(+) CCTCAA/GTGAAC 1 -- us2k10--------
    rs772171811,2
    F--7858815(+) GGTGAT/CACATG 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs1918386841,2
    --7858908(+) AAATAC/TAAAAT 1 -- us2k10--------
    rs12444551,2
    C,F,A,H--7858968(+) tacacT/Gtgagt 1 -- us2k114Minor allele frequency- G:0.06NS EA NA WA CSA 663
    rs1837321521,2
    --7859081(+) TGGCGC/GCGGTA 1 -- us2k10--------
    rs47476031,2
    C,F,A--7859082(+) GGCGGG/CGGTAG 1 -- us2k19Minor allele frequency- C:0.45NA WA EA 370

    HapMap Linkage Disequilibrium report for TAF3 (7860467 - 8058590 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for TAF3:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv104e201CNV Deletion23290073
    dgv103e201CNV Deletion23290073
    esv2732428CNV Deletion23290073
    esv1001263CNV Insertion20482838
    esv24837CNV Loss19812545
    nsv894851CNV Loss21882294
    nsv526540CNV Loss19592680
    esv26156CNV Gain19812545
    nsv526356CNV Gain19592680

    Human Gene Mutation Database (HGMD): TAF3
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606576    OMIM disorders: --

    3 diseases for TAF3:    About MalaCards
    herpes simplex    myocardial infarction    cerebritis


    TAF3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TAF3
    Human Genome Epidemiology (HuGE) Navigator: TAF3 (4 documents)

    Export disorders for TAF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TAF3 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with TAF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger. (PubMed id 11438666)1, 2, 3 Gangloff Y.G.... Davidson I. (Mol. Cell. Biol. 2001)
    2. Novel association strategy with copy number variation for identifying new risk Loci of human diseases. (PubMed id 20808825)1, 4 Chen X....Kong X. (PLoS ONE 2010)
    3. Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)1, 4 Luke M.M....Psaty B.M. ( a journal of cerebral circulation 2009)
    4. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (Gut 2009)
    5. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PubMed id 17975119)1, 4 Shiffman D....Psaty B.M. (Arterioscler. Thromb. Vasc. Biol. 2008)
    6. TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function. (PubMed id 18549481)1, 3 Bereczki O....Balint E. (BMC Mol. Biol. 2008)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    10. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83860 HGNC: 17303 AceView: TAF3 Ensembl:ENSG00000165632 euGenes: HUgn83860
    ECgene: TAF3 Kegg: 83860 H-InvDB: TAF3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TAF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TAF3 gene:
    Search GeneIP for patents involving TAF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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