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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAF1C Gene

protein-coding   GIFtS: 51
GCID: GC16M084211

TATA box binding protein (TBP)-associated factor, RNA polymerase...

(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
 Explore 5 diseases affiliated with
TAF1C via our new
 Human Malady Compendium 
Biological research products
for TAF1C
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C,
110kDa1 2
     TATA Box-Binding Protein-Associated Factor 1C2 3
TAFI1101 2 3 5     TBP-Associated Factor 1C2 3
SL11 2 5     TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kD1
MGC:399761 2     SL1, 110kD Subunit2
TAFI951 2     TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit C2
Transcription Initiation Factor SL1/TIF-IB Subunit C2 3     Transcription Factor SL12
RNA Polymerase I-Specific TBP-Associated Factor 110 KDa2 3     

External Ids:    HGNC: 115341   Entrez Gene: 90132   Ensembl: ENSG000001031687   OMIM: 6049055   UniProtKB: Q155723   

Export aliases for TAF1C gene to outside databases

Previous GC identifers: GC16M075062 GC16M085178 GC16M083950 GC16M083991 GC16M082768 GC16M069965


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAF1C:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding
protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds
to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory
signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding
different isoforms have been identified. (provided by RefSeq, Jul 2011)

UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572
Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC
(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is
primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of
TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3

Gene Wiki entry for TAF1C


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAF1C gene promoter:
         STAT5B   NF-1/L   NF-1   Pax-5   Olf-1   MyoD   GATA-2   AREB6   COMP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAF1C promoter sequence
   Search SABiosciences Chromatin IP Primers for TAF1C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF1C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24   Ensembl cytogenetic band:  16q24.1   HGNC cytogenetic band: 16q24

TAF1C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF1C gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M084211:  view genomic region     (about GC identifiers)

Start:
84,211,458 bp from pter      End:
84,220,669 bp from pter
Size:
9,212 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572 (See protein sequence)
Recommended Name: TATA box-binding protein-associated factor RNA polymerase I subunit C  
Size: 869 amino acids; 95213 Da
Subunit: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and
TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP
excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with MYC and RRN3. Interacts
with p53/TP53; the interaction prevents the association of SL1/TIF-IB with UBTF and represses RNA polymerase I
transcription
Subcellular location: Nucleus
Sequence caution: Sequence=BAD92831.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Secondary accessions: B7Z5K5 B7Z5S4 B7Z908 B7Z9L7 Q59F67 Q8N6V3
Alternative splicing: 5 isoforms:  Q15572-1   Q15572-2   Q15572-4   Q15572-5   Q15572-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TAF1C: NX_Q15572

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15572

  • TAF1C Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (7 alternative transcripts): 
    NP_001230085.1  NP_001230086.1  NP_001230087.1  NP_001230088.1  NP_001230089.1  NP_005670.3  NP_647610.2  

    ENSEMBL proteins: 
     ENSP00000345305   ENSP00000455265   ENSP00000456133   ENSP00000455933   ENSP00000455787  
     ENSP00000455247   ENSP00000456101   ENSP00000456011   ENSP00000457281   ENSP00000454854  
     ENSP00000454494   ENSP00000457883   ENSP00000367802   ENSP00000437900  
    Reactome Protein details: Q15572
    Human Recombinant Protein Products: 
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    Novus Biologicals TAF1C Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TAF1C

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--


    TAF1C for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q15572


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572
    Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC
    (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is
    primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
    stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of
    TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3

    miRNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding ----


    TAF1C for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/8 super-pathways (see all 8About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1RNA Polymerase I Chain Elongation
    RNA Polymerase I Chain Elongation1.00
    RNA Polymerase I Promoter Clearance0.86
    RNA Polymerase I Promoter Escape0.95
    RNA Polymerase I Transcription0.79
    RNA Polymerase I Transcription Initiation0.90
    Assembly of RNA Polymerase-I Initiation Complex0.32
    RNA Polymerase I Transcription Termination0.90
    2Assembly of RNA Polymerase-II Initiation Complex
    Protein Acetylation and Deacetylation0.51
    Crosstalk Between CARM1 and ESRs0.32
    3Transcription
    Transcription1.00
    4RNA Polymerase III Transcription Initiation
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    5Apoptotic Pathways in Synovial Fibroblasts
    Nuclear Receptor Activation by Vitamin-A0.57

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TAF1C (see all 6)
        Nuclear Receptor Activation by Vitamin-A
    Protein Acetylation and Deacetylation
    Assembly of RNA Polymerase-I Initiation Complex
    Glucocorticoid Receptor Signaling
    Estrogen Pathway

    5/9        Reactome Pathways for TAF1C (see all 9)
        RNA Polymerase I Transcription
    RNA Polymerase I Chain Elongation
    Transcription
    RNA Polymerase I Promoter Clearance
    RNA Polymerase I Promoter Escape



    TAF1C for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TAF1C

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/35 Interacting proteins for TAF1C (Q155722, 3 ENSP000003678024) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SETQ011052, 3, ENSP000003617774MINT-4543832 MINT-4544032 MINT-4543954 MINT-4544086 I2D: score=1 STRING: ENSP00000361777
    TBPP202262, 3, ENSP000002303544MINT-4543760 MINT-4544124 MINT-4329018 I2D: score=6 STRING: ENSP00000230354
    SMN1Q166372, 3MINT-8271575 I2D: score=2 
    SMN2Q166372, 3MINT-8271575 I2D: score=2 
    H2AFXP161042, 3MINT-8257966 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006360transcription from RNA polymerase I promoter TAS--
    GO:0006361transcription initiation from RNA polymerase I promoter TAS--
    GO:0006362transcription elongation from RNA polymerase I promoter TAS--
    GO:0006363termination of RNA polymerase I transcription TAS--


    TAF1C for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TAF1C for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAF1C
    1 Novoseek chemical compound relationship for TAF1C gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rrna 58.8 4 16033979 (1), 8609157 (1), 17251981 (1)

    Search CenterWatch for drugs/clinical trials and news about TAF1C 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TAF1C gene (7 alternative transcripts): 
    NM_001243156.1  NM_001243157.1  NM_001243158.1  NM_001243159.1  NM_001243160.1  NM_005679.3  NM_139353.2  

    Unigene Cluster for TAF1C:

    TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
    Hs.153022  [show with all ESTs]
    Unigene Representative Sequence: NM_005679
    18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000341690 ENST00000564774(uc010vnx.2 uc002fho.3 uc010vob.2)
    ENST00000564208(uc010vny.2) ENST00000567759(uc002fhn.3) ENST00000566903
    ENST00000566732 ENST00000544090 ENST00000563428 ENST00000570117 ENST00000568265
    ENST00000562445 ENST00000570270 ENST00000537450 ENST00000562330 ENST00000565279
    ENST00000561955 ENST00000569505 ENST00000564345

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    Additional cDNA sequence: 

    AK097031.1 AK299060.1 AK299347.1 AK304261.1 AK304739.1 AK315982.1 BC028131.1 L39059.1 

    17 DOTS entries:

    DT.91756320  DT.100817177  DT.75136465  DT.95156013  DT.75157385  DT.91756310  DT.120706095  DT.97780383 
    DT.95081649  DT.120706113  DT.75128266  DT.75154881  DT.95214266  DT.100708171  DT.120706057  DT.99945102 
    DT.95179571 

    24/169 AceView cDNA sequences (see all 169):

    CA397963 AI312042 AA641432 AW269860 AW236473 NM_139353 CA397964 CB305726 
    BX350449 AW161201 BQ065265 BM976286 BQ877823 BQ928487 CR605319 AI201588 
    AI963810 CA454870 NM_005679 BU857614 AI559694 AW590905 CA389989 AI361690 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for TAF1C (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a ·
    SP1:                                      -     -     -     -     -     -                                                                                   -   
    SP2:                                      -     -                       -                                                                                       
    SP3:                                      -                             -                             -     -     -     -     -     -     -     -     -     -   
    SP4:                                      -                             -                                                                                       
    SP5:                                      -     -                       -                                                                                       

    ExUns: 11b · 11c ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b · 17c ^ 18a · 18b
    SP1:  -                             -     -                                             
    SP2:                                                                                    
    SP3:  -                                                                                 
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for TAF1C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAF1C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTAAGGGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TAF1C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TAF1C

    SOURCE GeneReport for Unigene cluster: Hs.153022
        SABiosciences Custom PCR Arrays for TAF1C
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TAF1C gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Taf1c1 , 5 TATA box binding protein (Tbp)-associated factor, RNA more1, 5 74.07(n)1
    66.99(a)1
      8 (68.02 cM)5
    213411  NM_021441.21  NP_067416.21 
     1195979755 
    lizard
    (Anolis carolinensis)
    Reptilia TAF1C6
    --
    29(a)
    1 ↔ 1
    AAWZ02037297(3559-9972)
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch1073-170h8.36
    si:ch1073-170h8.3
    25(a)
    1 ↔ 1
    21(5787537-5815705)


    ENSEMBL Gene Tree for TAF1C (if available)
    TreeFam Gene Tree for TAF1C (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/377 NCBI SNPs in TAF1C are shown (see all 377    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs41501901,2
    C,F,--84211000(-) AGAGGC/TGGAGG 8 -- int1 ds50011Minor allele frequency- T:0.02NS 180
    rs41501891,2
    C,--84211187(-) GAGGCC/TGAGGC 8 -- ds5001 int11Minor allele frequency- T:0.01NS 180
    rs1928872711,2
    --84211227(+) ACCACA/GCCCAG 8 -- ds5001 int10--------
    rs22880241,2
    C,F,H,--84211465(+) ATATGT/CAGCAT 8 -- ut31 ese329Minor allele frequency- C:0.03NS EA NA 3334
    rs86921,2
    C,F,O,A,H,--84211483(-) TTTATA/GATTAA 8 -- ut3136Minor allele frequency- N:0.00MN EA NS NA CSA WA 3712
    rs41501861,2
    C,F,--84211514(-) GTTAAA/GATGTT 8 -- ut318Minor allele frequency- G:0.01NS NA CSA WA 438
    rs1397414371,2
    --84211595(+) CCAACC/GTGAAA 8 -- int1 ut310--------
    rs41501851,2
    C,F,H,--84211620(-) ATGACA/GTAGTA 8 -- int1 ut3123Minor allele frequency- G:0.02NS EA NA WA 2578
    rs10566161,2
    C,F,H,--84211718(-) TCCTCG/AGAGTT 8 -- int1 ut31 ese334Minor allele frequency- A:0.16NS MN EA NA CSA WA 3742
    rs41501841,2
    H--84211719(-) TTCCTC/TGGAGT 8 -- ut31 int1 ese3 trp35Minor allele frequency- T:0.00NS EA 578

    HapMap Linkage Disequilibrium report for TAF1C (84211458 - 84220669 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TAF1C: --
    Human Gene Mutation Database (HGMD): TAF1C

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAF1C
    DNA2.0 Custom Variant and Variant Library Synthesis for TAF1C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TAF1C for disorders           About GeneDecksing

    OMIM gene information: 604905    OMIM disorders: --

    5 diseases for TAF1C:    About MalaCards
    hepatitis c    myeloid leukemia    choroiditis    hepatitis
    leukemia

    Human Genome Epidemiology (HuGE) Navigator: TAF1C (3 documents)

    Export disorders for TAF1C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAF1C gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with TAF1C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. (PubMed id 7801123)1, 2, 3 Comai L....Tjian R. (1994)
    2. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. (PubMed id 15723054)1, 2 Grandori C.... White R.J. (2005)
    3. TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter. (PubMed id 15970593)1, 2 Friedrich J.K.... Zomerdijk J.C.B.M. (2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. hRRN3 is essential in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters. (PubMed id 11250903)1, 2 Miller G.... Zomerdijk J.C.B.M. (2001)
    7. Repression of RNA polymerase I transcription by the tumor suppressor p53. (PubMed id 10913176)1, 2 Zhai W. and Comai L. (2000)
    8. A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription. (PubMed id 17318177)1, 9 Gorski J.J.... Zomerdijk J.C.B.M. (2007)
    9. Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1. (PubMed id 10894955)1, 9 Di Pietro C....Purrello M. (2000)
    10. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. (PubMed id 16055704)1, 9 Zhang C....Johnson D.L. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9013 HGNC: 11534 AceView: TAF1C Ensembl:ENSG00000103168 euGenes: HUgn9013
    ECgene: TAF1C H-InvDB: TAF1C

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAF1C Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/taf1c/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TAF1C gene:
    Search GeneIP for patents involving TAF1C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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