TAF1C Gene
protein-coding GIFtS: 51
GCID: GC16M084211
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TATA box binding protein (TBP)-associated factor, RNA polymerase...(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
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Aliases for TAF1C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C,110kDa1 2 | | TATA Box-Binding Protein-Associated Factor 1C2 3 | | TAFI1101 2 3 5 | | TBP-Associated Factor 1C2 3 | | SL11 2 5 | | TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kD1 | | MGC:399761 2 | | SL1, 110kD Subunit2 | | TAFI951 2 | | TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit C2 | | Transcription Initiation Factor SL1/TIF-IB Subunit C2 3 | | Transcription Factor SL12 | | RNA Polymerase I-Specific TBP-Associated Factor 110 KDa2 3 | | |
Export aliases for TAF1C gene to outside databasesPrevious GC identifers: GC16M075062 GC16M085178 GC16M083950 GC16M083991 GC16M082768 GC16M069965 |
Summaries for TAF1C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TAF1C: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-bindingprotein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, bindsto the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatorysignals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified. (provided by RefSeq, Jul 2011) UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably isprimarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved instabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association ofTBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3 Gene Wiki entry for TAF1C
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Genomic Views for TAF1C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TAF1C gene promoter: STAT5B NF-1/L NF-1 Pax-5 Olf-1 MyoD GATA-2 AREB6 COMP1 Other transcription factors
Search SABiosciences Chromatin IP Primers for TAF1C
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF1C |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24 Ensembl cytogenetic band: 16q24.1 HGNC cytogenetic band: 16q24TAF1C Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M084211: view genomic region
(about GC identifiers)
Start:
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84,211,458 bp from pter |
End:
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84,220,669 bp from pter |
Size:
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9,212 bases |
Orientation:
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minus strand |
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Proteins for TAF1C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572 (See
protein sequence)Recommended Name: TATA box-binding protein-associated factor RNA polymerase I subunit C Size: 869 amino acids; 95213 Da
Subunit: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C andTAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBPexcludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with MYC and RRN3. Interactswith p53/TP53; the interaction prevents the association of SL1/TIF-IB with UBTF and represses RNA polymerase Itranscription
Subcellular location: Nucleus
Sequence caution: Sequence=BAD92831.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Secondary accessions: B7Z5K5 B7Z5S4 B7Z908 B7Z9L7 Q59F67 Q8N6V3Alternative splicing: 5 isoforms: Q15572-1 Q15572-2 Q15572-4 Q15572-5 Q15572-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TAF1C: NX_Q15572
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15572 TAF1C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001230085.1 NP_001230086.1 NP_001230087.1 NP_001230088.1 NP_001230089.1 NP_005670.3 NP_647610.2 ENSEMBL proteins: ENSP00000345305 ENSP00000455265 ENSP00000456133 ENSP00000455933 ENSP00000455787 ENSP00000455247 ENSP00000456101 ENSP00000456011 ENSP00000457281 ENSP00000454854 ENSP00000454494 ENSP00000457883 ENSP00000367802 ENSP00000437900 Reactome Protein details: Q15572 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005654 | nucleoplasm |
TAS | -- |
TAF1C for ontologies About GeneDecksing
TAF1C Antibody Products: Assay Products for TAF1C: |
Protein
Domains / Families for TAF1C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q15572 |
Function for TAF1C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: TAF1C_HUMAN, Q15572Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably isprimarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved instabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association ofTBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TAF1C (NM_139353) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TAF1C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF1C  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF1C |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
TAF1C for ontologies About GeneDecksing
|
Pathways & Interactions for TAF1C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA Polymerase I Chain Elongation | | | 2 | Assembly of RNA Polymerase-II Initiation Complex | | | 3 | Transcription | | | 4 | RNA Polymerase III Transcription Initiation | | | 5 | Apoptotic Pathways in Synovial Fibroblasts | |
Pathway sources See GeneCards unified pathways Show all pathways
5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TAF1C (see all 6) 5/9
Reactome Pathways for TAF1C (see all 9)
TAF1C for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TAF1C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/35 Interacting proteins for TAF1C (Q155722, 3 ENSP000003678024) via UniProtKB, MINT, STRING, and/or I2D (see all 35)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0006360 | transcription from RNA polymerase I promoter |
TAS | -- | | GO:0006361 | transcription initiation from RNA polymerase I promoter |
TAS | -- | | GO:0006362 | transcription elongation from RNA polymerase I promoter |
TAS | -- | | GO:0006363 | termination of RNA polymerase I transcription |
TAS | -- |
TAF1C for ontologies About GeneDecksing
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Drugs & Compounds for TAF1C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TAF1C for compounds About GeneDecksing
Browse Tocris compounds for TAF1C 1 Novoseek chemical compound relationship for TAF1C gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| rrna |
58.8 |
4 |
16033979 (1), 8609157 (1), 17251981 (1) |
Search CenterWatch for drugs/clinical trials and news about TAF1C 
|
Transcripts for TAF1C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TAF1C gene (7 alternative transcripts): NM_001243156.1 NM_001243157.1 NM_001243158.1 NM_001243159.1 NM_001243160.1 NM_005679.3 NM_139353.2 Unigene Cluster for TAF1C: TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Hs.153022 [show with all ESTs]Unigene Representative Sequence: NM_00567918/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000341690 ENST00000564774(uc010vnx.2 uc002fho.3 uc010vob.2) ENST00000564208(uc010vny.2) ENST00000567759(uc002fhn.3) ENST00000566903 ENST00000566732 ENST00000544090 ENST00000563428 ENST00000570117 ENST00000568265 ENST00000562445 ENST00000570270 ENST00000537450 ENST00000562330 ENST00000565279 ENST00000561955 ENST00000569505 ENST00000564345
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TAF1C (NM_139353) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TAF1C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF1C  |
Additional cDNA sequence: AK097031.1 AK299060.1 AK299347.1 AK304261.1 AK304739.1 AK315982.1 BC028131.1 L39059.1 17 DOTS entries: DT.91756320 DT.100817177 DT.75136465 DT.95156013 DT.75157385 DT.91756310 DT.120706095 DT.97780383 DT.95081649 DT.120706113 DT.75128266 DT.75154881 DT.95214266 DT.100708171 DT.120706057 DT.99945102 DT.95179571 24/169 AceView cDNA sequences (see all 169): CA397963 AI312042 AA641432 AW269860 AW236473 NM_139353 CA397964 CB305726 BX350449 AW161201 BQ065265 BM976286 BQ877823 BQ928487 CR605319 AI201588 AI963810 CA454870 NM_005679 BU857614 AI559694 AW590905 CA389989 AI361690 GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for TAF1C (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 11b | · | 11c | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18a | · | 18b | |
| SP1: | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for TAF1C
|
Expression for TAF1C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TAF1C expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCTAAGGGAG
About this image See TAF1C Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TAF1C
SOURCE GeneReport for Unigene cluster: Hs.153022 SABiosciences Custom PCR Arrays for TAF1C
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF1C Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TAF1C | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAF1C | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF1C | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF1C |
Orthologs for TAF1C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TAF1C gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for TAF1C (if available) TreeFam Gene Tree for TAF1C (if available)  |
Paralogs for TAF1C gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for TAF1C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TAF1C (84211458 - 84220669 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for TAF1C: -- Human Gene Mutation Database (HGMD): TAF1C
 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for TAF1C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TAF1C for disorders About GeneDecksing
OMIM gene information: 604905
OMIM disorders: --
5 diseases for TAF1C: About MalaCardshepatitis c myeloid leukemia choroiditis hepatitis leukemia Human Genome Epidemiology (HuGE) Navigator: TAF1C (3 documents) Export disorders for TAF1C gene to outside databases
|
Publications for TAF1C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TAF1C gene, integrated from 9 sources (see all 55): (articles sorted by number of sources associating them with TAF1C) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. (PubMed id 7801123)1, 2, 3 Comai L....Tjian R. (1994)
- c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. (PubMed id 15723054)1, 2 Grandori C.... White R.J. (2005)
- TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter. (PubMed id 15970593)1, 2 Friedrich J.K.... Zomerdijk J.C.B.M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- hRRN3 is essential in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters. (PubMed id 11250903)1, 2 Miller G.... Zomerdijk J.C.B.M. (2001)
- Repression of RNA polymerase I transcription by the tumor suppressor p53. (PubMed id 10913176)1, 2 Zhai W. and Comai L. (2000)
- A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription. (PubMed id 17318177)1, 9 Gorski J.J.... Zomerdijk J.C.B.M. (2007)
- Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1. (PubMed id 10894955)1, 9 Di Pietro C....Purrello M. (2000)
- PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. (PubMed id 16055704)1, 9 Zhang C....Johnson D.L. (2005)
|
External Searches for TAF1C gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TAF1C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TAF1C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TAF1C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for TAF1C | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/taf1c/ |
|
| | |
About This Section
| Patent Information for TAF1C gene: Search GeneIP for patents involving TAF1C
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for TAF1C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for TAF1C | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAF1C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAF1C | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TAF1C | | OriGene 3'-UTR Clone for TAF1C | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAF1C | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TAF1C | | OriGene Custom Protein Services for TAF1C | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TAF1C | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAF1C | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAF1C | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAF1C | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAF1C | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAF1C |
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| | | Search Tocris compounds for TAF1C |
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 | | TAF1C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF1C |
|  |  |  | | | Search ThermoFisher Antibodies for TAF1C |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAF1C |
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