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TAF1A Gene

protein-coding   GIFtS: 54
GCID: GC01M222731

TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase...

(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A,
48kDa1 2
     RAFI482 5
Transcription Factor SL12 3     SL12 5
Transcription Initiation Factor SL1/TIF-IB Subunit A2 3     TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A,
48kD1
TAFI482 3     MGC:170612
RNA Polymerase I-Specific TBP-Associated Factor 48 KDa2 3     SL1, 48kD Subunit2
TATA Box-Binding Protein-Associated Factor 1A2 3     TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit A2
TBP-Associated Factor 1A2 3     

External Ids:    HGNC: 115321   Entrez Gene: 90152   Ensembl: ENSG000001434987   OMIM: 6049035   UniProtKB: Q155733   

Export aliases for TAF1A gene to outside databases

Previous GC identifers: GC01M221325 GC01M218646 GC01M219263 GC01M219787 GC01M219119 GC01M220797 GC01M193405


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TAF1A Gene:
This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a
TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I
preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple
isoforms.(provided by RefSeq, Jan 2011)

GeneCards Summary for TAF1A Gene:
TAF1A (TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa) is a protein-coding gene.

UniProtKB/Swiss-Prot: TAF1A_HUMAN, Q15573
Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC
(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is
primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association
of TBP with TFIID subunits

Gene Wiki entry for TAF1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TAF1A
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAF1A promoter sequence
   Search Chromatin IP Primers for TAF1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAF1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q42

TAF1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAF1A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M222731:  view genomic region     (about GC identifiers)

Start:
222,731,244 bp from pter      End:
222,763,275 bp from pter
Size:
32,032 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TAF1A_HUMAN, Q15573 (See protein sequence)
Recommended Name: TATA box-binding protein-associated factor RNA polymerase I subunit A  
Size: 450 amino acids; 52676 Da
Subunit: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B,
TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB
subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with
UBFT
Secondary accessions: B2RDZ8 D3DTB7 Q9NWA1
Alternative splicing: 2 isoforms:  Q15573-1   Q15573-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TAF1A: NX_Q15573

Explore proteomics data for TAF1A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TAF1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001188465.1  NP_005672.1  NP_647603.1  

    ENSEMBL proteins: 
     ENSP00000355856   ENSP00000327072   ENSP00000375755   ENSP00000339976   ENSP00000375754  
     ENSP00000437725  
    Reactome Protein details: Q15573

    TAF1A Human Recombinant Protein Products:

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    antibodies-online proteins for TAF1A (5 products) 

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR016629 RNA_pol_I_TAF1A/TAFI48

    Graphical View of Domain Structure for InterPro Entry Q15573

    ProtoNet protein and cluster: Q15573


    Find genes that share domains with TAF1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TAF1A_HUMAN, Q15573
    Function: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC
    (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is
    primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
    stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association
    of TBP with TFIID subunits

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI17318177
         
    Find genes that share ontologies with TAF1A           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TAF1A

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    miRTarBase miRNAs that target TAF1A:
    hsa-mir-124-3p (MIRT022398)

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    hsa-miR-520d-5p hsa-miR-3613-3p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidTAF1A 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TAF1A_HUMAN, Q15573: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton3
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000120RNA polymerase I transcription factor complex IEA--
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0015630microtubule cytoskeleton IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    Find genes that share ontologies with TAF1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TAF1A About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Escape
    RNA Polymerase I Promoter Escape0.88
    RNA Polymerase I Transcription Initiation0.55
    RNA Polymerase I Transcription Termination0.88
    Assembly of RNA Polymerase-I Initiation Complex0.32
    2RNA Polymerase I Promoter Opening
    RNA Polymerase I Transcription0.78
    RNA Polymerase I Promoter Clearance0.78
    RNA Polymerase I Chain Elongation0.78
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.73
    3Assembly of RNA Polymerase-II Initiation Complex
    Protein Acetylation and Deacetylation0.51
    Crosstalk Between CARM1 and ESRs0.39
    4Apoptotic Pathways in Synovial Fibroblasts
    Nuclear Receptor Activation by Vitamin-A0.57
    5GPCR Pathway
    Estrogen Pathway0.55


    Find genes that share SuperPaths with TAF1A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for TAF1A (see all 6)
        Nuclear Receptor Activation by Vitamin-A
    Protein Acetylation and Deacetylation
    Assembly of RNA Polymerase-I Initiation Complex
    Glucocorticoid Receptor Signaling
    Estrogen Pathway

    Selected Reactome Pathways for TAF1A (see all 6)
        RNA Polymerase I Chain Elongation
    SIRT1 negatively regulates rRNA Expression
    RNA Polymerase I Promoter Escape
    NoRC negatively regulates rRNA expression
    RNA Polymerase I Transcription Termination


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAF1A
    Interactions:

        GeneGlobe Interaction Network for TAF1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TAF1A (Q155731, 2, 3 ENSP000003270724) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST4H4P628053, ENSP000003507674I2D: score=2 STRING: ENSP00000350767
    HIST1H4AP628053, ENSP000003529804I2D: score=2 STRING: ENSP00000352980
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006360transcription from RNA polymerase I promoter TAS--
    GO:0006361transcription initiation from RNA polymerase I promoter TAS--
    GO:0006362transcription elongation from RNA polymerase I promoter TAS--
    GO:0006363termination of RNA polymerase I transcription TAS--

    Find genes that share ontologies with TAF1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for TAF1A

    1 Novoseek inferred chemical compound relationship for TAF1A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    s-napc 93.1 1 8339931 (1)



    Find genes that share compounds with TAF1A           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TAF1A gene (3 alternative transcripts): 
    NM_001201536.1  NM_005681.3  NM_139352.2  

    Unigene Cluster for TAF1A:

    TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
    Hs.153088  [show with all ESTs]
    Unigene Representative Sequence: NM_001201536
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366890(uc009xdy.1) ENST00000352967(uc001hnj.3) ENST00000391883
    ENST00000487009 ENST00000480065 ENST00000465263 ENST00000350027(uc009xdz.2 uc001hni.2)
    ENST00000391882 ENST00000543857(uc010pur.2)
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    hsa-miR-520d-5p hsa-miR-3613-3p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidTAF1A 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat TAF1A
      QuantiFast Probe-based Assays in human, mouse, rat TAF1A

    Additional mRNA sequence: 

    AK001054.1 AK290970.1 AK299536.1 AK307882.1 AK315740.1 BC013808.1 L39060.1 

    7 DOTS entries:

    DT.209757  DT.100021120  DT.40118127  DT.91738665  DT.100752251  DT.100739188  DT.91738658 

    Selected AceView cDNA sequences (see all 36):

    L39060 BU179101 BU192019 AU118970 BM845364 N66196 BQ051078 BM841948 
    AI292312 BG505180 BC013808 BI089656 BX373108 AL527402 BE895004 BX505527 
    AA743681 BQ574624 BX118609 N39785 BU839228 AI276269 AU145413 AA305702 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TAF1A (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                            -                                               -                                       
    SP2:                                      -     -                                               -                             -         
    SP3:                                            -     -                                                                                 
    SP4:                                            -     -     -                                                                           
    SP5:                                                                                                                                    


    ECgene alternative splicing isoforms for TAF1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAF1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAAAATAC
    TAF1A Expression
    About this image


    TAF1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
    TAF1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TAF1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.153088
        Custom PCR Arrays for TAF1A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAF1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TAF1A gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Taf1a1 , 5 TATA box binding protein (Tbp)-associated factor, RNA more1, 5 81.03(n)1
    79.91(a)1
      15
    213391  NM_001277959.11  NP_001264888.11 
     1833889815 
    chicken
    (Gallus gallus)
    Aves TAF1A1 TATA box binding protein (TBP)-associated factor, RNA more 59.81(n)
    49.28(a)
      421338  NM_001277561.1  NP_001264490.1 
    lizard
    (Anolis carolinensis)
    Reptilia TAF1A6
    TATA box binding protein (TBP)-associated factor, ...
    44(a)
    1 ↔ 1
    1(244390319-244404394)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia taf1a1 TATA box binding protein (TBP)-associated factor, RNA more 55.05(n)
    44.19(a)
      100497125  XM_002940699.2  XP_002940745.2 
    zebrafish
    (Danio rerio)
    Actinopterygii taf1a1 TATA box binding protein (TBP)-associated factor, RNA more 50.79(n)
    42.63(a)
      567105  NM_001045274.1  NP_001038739.1 


    ENSEMBL Gene Tree for TAF1A (if available)
    TreeFam Gene Tree for TAF1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TAF1A (see all 559)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1168293941,2
    C,F--222730824(+) AGTCTC/TGCTCT 2 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1846615121,2
    --222730868(+) GCTCAC/TTGCAG 2 -- ds50010--------
    rs1407617101,2
    --222730895(+) TCAAGC/TGATTC 2 -- ds50010--------
    rs1889782071,2
    --222730896(+) CAAGCA/GATTCT 2 -- ds50010--------
    rs1932988891,2
    --222730919(+) TCCCAA/GATAGC 2 -- ds50010--------
    rs778157531,2
    C,F--222730939(+) AAGCGC/TGCACC 2 -- ds50014Minor allele frequency- T:0.21WA NA EA 242
    rs354101331,2
    C--222730960(+) GCTAA-/TTTTTT 2 -- ds50010--------
    rs1127528621,2
    F--222730972(+) TTTGGC/TATTTT 2 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1855130381,2
    --222731059(+) AGGCAC/TCAAAA 2 -- ds50010--------
    rs1384304041,2
    --222731116(+) GCCCAC/TTCTAC 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for TAF1A (222731244 - 222763275 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TAF1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv873205CNV Loss21882294
    nsv873203CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604903    OMIM disorders: --


    Find genes that share disorders with TAF1A           About GenesLikeMe


    Export disorders for TAF1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TAF1A gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with TAF1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. (PubMed id 7801123)1, 2, 3, 9 Comai L....Tjian R. (Science 1994)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Identification of a domain within human TAF(I)48, a subunit of Selectivity Factor 1, that interacts with helix 2 of TBP. (PubMed id 15315821)1, 9 Xu S. and Hori R.T. (Gene 2004)
    6. Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1. (PubMed id 10894955)1, 9 Di Pietro C.... Purrello M. (Cytogenet. Cell Genet. 2000)
    7. TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription. (PubMed id 8013460)1, 9 Rudloff U....Grummt I. (EMBO J. 1994)
    8. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. The hepatitis delta virus RNA genome interacts with the human RNA polymerases I and III. (PubMed id 19246067)1 Greco-Stewart V.S....Pelchat M. (Virology 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9015 HGNC: 11532 AceView: TAF1A.1 Ensembl:ENSG00000143498 euGenes: HUgn9015
    ECgene: TAF1A H-InvDB: TAF1A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TAF1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TAF1A gene:
    Search GeneIP for patents involving TAF1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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