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TAF15 Gene

protein-coding GIFtS: 57

GC17P031160

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
(Previous names: TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: TAF2N)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
Npl3 ^¹, ²
RBP56 ^¹, ², ³, ⁵
TAF(II)68 ^³
TAF2N ^², ³, ⁵
TAFII68 ^², ³
hTAFII68 ^¹, ²

Descriptions
RBP56/CSMF fusion ^²
RNA-binding protein 56 ^², ³
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kD ^²
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa ^²
TAF15 RNA polymerase II, TATA box binding protein-associated factor, 68kDa ^¹
TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) ^¹, ²
TATA box-binding protein-associated factor 2N (RNA-binding protein 56) ^²
TBP-associated factor 15 ^²

External Ids
HGNC: 11547¹
Entrez Gene: 8148²
UniProtKB: Q92804³
Ensembl: ENSG00000172660⁷

Search outside databases for aliases for TAF15 gene

Previous GC identifers: GC17P033906 GC17P036172 GC17P033985 GC17P034282

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TAF15:

Initiation of transcription by RNA polymerase II requires the activities of more than 70

polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID),

which binds to the core promoter to position the polymerase properly, serves as the scaffold for

assembly of the remainder of the transcription complex, and acts as a channel for regulatory

signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily

conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal

transcription, serve as coactivators, function in promoter recognition or modify general

transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This

gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving

chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in

a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal

myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.

[provided by RefSeq]

UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804

Function: RNA and ssDNA-binding protein that may play specific roles during transcription

initiation at distinct promoters. Can enter the preinitiation complex together with the RNA

polymerase II (Pol II)

Gene Wiki entry for TAF15

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TAF15 gene

Entrez Gene cytogenetic band: 17q11.1-q11.2 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q11.1-q11.2

TAF15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P031160: (about GC identifiers)

Start:	31,160,596 bp from pter
End:	31,198,351 bp from pter
Size:	37,756 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000017.9 NT_010799.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804 (See protein sequence)

Recommended Name: TATA-binding protein-associated factor 2N

Size: 592 amino acids; 61830 Da

Subunit: Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together

with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1

Subcellular location: Nucleus (Potential)

Secondary accessions: Q92751

Alternative splicing: 2 isoforms: Q92804-1 Q92804-2

Post-translational modifications:

Arg-206 is dimethylated, probably to asymmetric dimethylarginine¹

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_003478.1 NP_631961.1

ENSEMBL proteins:

ENSP00000309558 ENSP00000378041

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TAF15)
	Human Recombinant Proteins from Abnova (TAF15)

OriGene Purified Recombinant Human Protein: TAF15

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IEA	--

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Antibodies for TAF15:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of TAF15
	Sigma-Aldrich Antibodies for TAF15
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TAF15), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TAF15)
	Novus Biologicals Antibodies for TAF15

Assays for TAF15:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q92804

ProtoNet protein and cluster: Q92804

2 Blocks protein families:

IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

IPB001876 Zn-finger

UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804

Similarity: Belongs to the RRM TET family

Similarity: Contains 1 RanBP2-type zinc finger

Similarity: Contains 1 RRM (RNA recognition motif) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF15)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAF15)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_003487

Applied Biosystems Silencer® siRNAs for TAF15

Sigma-Aldrich siRNA for TAF15

Sigma-Aldrich shRNA for TAF15

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TAF15
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003487
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003487
untagged cDNA clones in CMV expression vector (see all 2): NM_003487

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_139215

UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804

Function: RNA and ssDNA-binding protein that may play specific roles during transcription

initiation at distinct promoters. Can enter the preinitiation complex together with the RNA

polymerase II (Pol II)

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003723	RNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for TAF15 (Your Favorite Gene powered by Ingenuity)

Estrogen Receptor Signaling
Glucocorticoid Receptor Signaling

GeneDecks TAF15 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for TAF15

5/13 Interacting proteins for TAF15 (ENSP00000309558³) via UniProtKB, MINT, and/or STRING (see all 13 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TBP	ENSP00000230354³	STRING (score=.983)
NR4A3	ENSP00000333122³	STRING (score=.925)
ZNF384	ENSP00000321650³	STRING (score=.886)
PRMT1	ENSP00000246789³	STRING (score=.85)
TAF13	ENSP00000355051³	STRING (score=.85)

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TAF15

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAF15)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAF15)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_003487

Sigma-Aldrich siRNA for TAF15

Sigma-Aldrich shRNA for TAF15

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003487 NM_139215

REFSEQ mRNAs for TAF15 gene (2 alternative transcripts):

NM_003487.2 NM_139215.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003487 NM_139215

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003487
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003487
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_003487

Additional cDNA sequence:

AK000881.1 AK000942.1 AK022003.1 AK130999.1 AK304520.1 AK307637.1 AK313223.1 AK314194.1

BC030591.2 BC039129.1 BC046099.1 BC048985.1 U51334.1 X98893.1

22 DOTS entries:

DT.212660 DT.95125326 DT.100777303 DT.91768446 DT.92066613 DT.75169741 DT.120906110 DT.120906141

DT.423558 DT.95358439 DT.101962968 DT.120906140 DT.91768444 DT.91973540 DT.100023625 DT.120906190

DT.306380 DT.91768450 DT.91918658 DT.92004256 DT.95125327 DT.95253068

24/216 AceView cDNA sequences (see all 216 ):

AW117240 BC030591 AL702463 BM848308 AW104422 AI301573 AU077342 BU543375

BC046099 BM915658 BC048985 BF732740 BU161472 BU541157 BX111719 BE644621

NM_139215 AW294733 BC039129 BU543864 BQ069861 AI636891 BU688925 BF724572

highest scoring ESTs for TAF15:

U51334 AA662359 AA765679 AA857343 AA862078 AA910882 AA918903 AI679882 AI800559 AL516729

Unigene Cluster for TAF15:

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

Hs.402752 [show with all ESTs]

Unigene Representative Sequence: BC046099

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TAF15 (see all 8 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5a	·	5b	^	6	^	7a	·	7b	^	8	^	9a	·	9b	^	10a	·	10b	^	11	^	12	^	13	^	14	^	15	^	16	^	17
SP1:																					-				-
SP2:											-										-
SP3:
SP4:
SP5:													-

About this scheme

ECgene alternative splicing isoforms for TAF15

2 Ensembl transcripts including schematic representations:

ENST00000311979 ENST00000394533

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TAF15 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TAF15

¹ / ² / ³

3 probe-sets matching TAF15 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36822_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U51334	1.00	1.00	1.00	1
202840_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003487	0.60	1.00	0.82	1
202840_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATCCATAGTG

SOURCE GeneReport for Unigene cluster: Hs.402752
Expression variation in blood from EXPOLDB for TAF15
UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804
Tissue specificity: Ubiquitous. Observed in all fetal and adult tissues

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TAF15 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TAF15¹	--	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated more	92.95(n) 95.94(a)	491135 XM_548255.2 XP_548255.2
chimpanzee (Pan troglodytes)	TAF15¹	--	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated more	99.77(n) 99.66(a)	454590 XM_511417.2 XP_511417.2
cow (Bos taurus)	TAF15¹	--	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated more	94.4(n) 96.43(a)	536067 XM_866591.2 XP_871684.2
rat (Rattus norvegicus)	Taf15¹	--	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated more	91.88(n) 94.5(a)	287571 XM_237792.4 XP_237792.4
mouse (Mus musculus)	Taf15^{1, 5}	11⁵	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated more^{1, 5}	92.1(n)¹ 95.33(a)¹	70439¹ NM_027427.2¹ NP_081703.1¹ AK049911⁵ AK051568⁵ (see all 11)

About this table Species with no ortholog for TAF15

ENSEMBL Gene Tree for TAF15

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for TAF15 gene

FUS² EWSR1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/248 NCBI SNPs in TAF15 are shown (see all 248 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 70)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs4251703^1,2	C,F,H	31159071(+)	`GAAGGT/CATTAA`	2	--	ng5¹		14	NS EU EA WA NA	1346
	rs4251699^1,2	C,F,H	31158738(+)	`TCCTTC/TTTTGA`	2	--	ng5¹ trp³		11	NS EU EA WA	1246
	rs4251710^1,2	C,F,H	31160150(+)	`GTCCCA/CGAGCT`	2	--	ng5¹		7	NS EU EA WA MN	1820
	rs965984^1,2	C,F,H	31198620(-)	`CATACC/TTCATT`	2	--	ng3¹		11	NA EA EU WA NS	988
	rs4251708^1,2	C,F,H	31160039(+)	`ACGATT/GTCGTT`	2	--	ng5¹		11	NS EU EA WA	1246
	rs4251702^1,2	C,F,H	31159050(+)	`CTCACG/TTCTTT`	2	--	ng5¹		9	NS EU EA WA	996
	rs4251704^1,2	F,H	31159364(+)	`attggT/Cctctg`	2	--	ng5¹		5	NS EU EA WA	584
	rs4251701^1,2	F,H	31158956(+)	`GTCTTG/TCTTGT`	2	--	ng5¹		5	NS EU EA WA	584
	rs4251700^1,2	F,H	31158789(+)	`CCCTCT/GAGGTC`	2	--	ng5¹		5	NS EU EA WA	548
	rs4251706^1,2	F,H	31159852(+)	`tacgaC/Tctagg`	2	--	ng5¹		5	NS EU EA WA	578

About this table

HapMap Linkage Disequilibrium images for TAF15 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601574 disorders: 612237

UniProtKB/Swiss-Prot: RBP56_HUMAN, Q92804

A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid

chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3

5 Novoseek disease relationships for TAF15 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
chondrosarcoma	76.81	6	10537274 (1), 10602519 (1), 11156374 (1), 18330902 (1)
ewings sarcoma	68.29	4	17106916 (2), 12359745 (1), 18330902 (1)
sarcoma	49.73	3	8890175 (1), 10602519 (1), 18620564 (1)
cancer	3.92	1	15094065 (1)
tumors	0.00	1	12378528 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/34 PubMed articles for TAF15 gene (see all 34 ):

Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes. (PubMed id 9795213)^{1, 2, 3, 4} Morohoshi F....Ohki M. (1998)
Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins. (PubMed id 8954779)^{2, 3, 4} Morohoshi F.... Ohki M. (1996)
hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. (PubMed id 8890175)^{1, 3, 4} Bertolotti A.... Tora L. (1996)
Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. (PubMed id 15782174)^{3, 4} Ong S.E.... Mann M. (2004)
The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription. (PubMed id 9660765)^{3, 4} Zhang D.... Childs G. (1998)
Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src. (PubMed id 15094065)^{1, 3} Lee H.J....Kim J. (2004)
EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes. (PubMed id 9488465)^{1, 3} Bertolotti A....Tora L. (1998)
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response. (PubMed id 18620564)^{1, 3} Andersson M.K....Aman P. (2008)
Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia. (PubMed id 12359745)^{1, 3} Martini A....Marynen P. (2002)
The hTAF II 68-TEC fusion protein functions as a strong transcriptional activator. (PubMed id 18330902)^{1, 3} Kim S....Kim J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8148	HGNC: 11547	AceView: TAF15	Ensembl:ENSG00000172660	euGenes: HUgn8148
ECgene: TAF15	H-InvDB: TAF15

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for TAF15	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/taf15/

Licensable Technologies for TAF15
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for TAF15:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TAF15-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TAF15		Antibodies for TAF15
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TAF15		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (TAF15)
	Antibodies (TAF15)
	Chimera RNAi (TAF15)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (TAF15)
	Antibodies (TAF15)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for TAF15

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for TAF15

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TAF15 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for TAF15

Summaries
for TAF15

Genomic Location
for TAF15

Proteins
for TAF15

Protein Domains/
Families
for TAF15

Gene Function
for TAF15

Pathways & Interactions
for TAF15

Drugs & Compounds
for TAF15

Transcripts
for TAF15

Expression
for TAF15

Orthologs
for TAF15

Paralogs
for TAF15

SNPs/Variants
for TAF15

Disorders & Mutations
for TAF15

Medical News
for TAF15

Publications
for TAF15

Search for TAF15

Genome Databases showing TAF15

Other Databases showing TAF15

Specialized Databases showing TAF15

Licensable Technologies
for TAF15

Services
for TAF15

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TAF15 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor TAF15

Summariesfor TAF15

Genomic Locationfor TAF15

Proteinsfor TAF15

Protein Domains/Familiesfor TAF15

Gene Functionfor TAF15

Pathways & Interactionsfor TAF15

Drugs & Compoundsfor TAF15

Transcriptsfor TAF15

Expression for TAF15

Orthologsfor TAF15

Paralogsfor TAF15

SNPs/Variantsfor TAF15

Disorders & Mutationsfor TAF15

Medical Newsfor TAF15

Publicationsfor TAF15

Search for TAF15

Genome Databases showing TAF15

Other Databases showing TAF15

Specialized Databases showing TAF15

Licensable Technologiesfor TAF15

Servicesfor TAF15

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TAF15

Summaries
for TAF15

Genomic Location
for TAF15

Proteins
for TAF15

Protein Domains/
Families
for TAF15

Gene Function
for TAF15

Pathways & Interactions
for TAF15

Drugs & Compounds
for TAF15

Transcripts
for TAF15

Expression
for TAF15

Orthologs
for TAF15

Paralogs
for TAF15

SNPs/Variants
for TAF15

Disorders & Mutations
for TAF15

Medical News
for TAF15

Publications
for TAF15

Licensable Technologies
for TAF15

Services
for TAF15