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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TADA3 Gene

protein-coding   GIFtS: 54
GCID: GC03M009797

Transcriptional Adaptor 3

(Previous names: transcriptional adaptor 3 (NGG1 homolog, yeast)-like)
(Previous symbol: TADA3L)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcriptional Adaptor 31 2     hADA32 3
TADA3L1 2 3 5     Transcriptional Adaptor 3 (NGG1 Homolog, Yeast)-Like1
ADA32 3 5     NGG12
STAF542 3     Transcriptional Adapter 32
ADA3 Homolog2 3     Transcriptional Adapter 3-Like3
ADA3-Like Protein2 3     

External Ids:    HGNC: 194221   Entrez Gene: 104742   Ensembl: ENSG000001711487   OMIM: 6029455   UniProtKB: O755283   

Export aliases for TADA3 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TADA3 Gene:
DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the
transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by
acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator
adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in
chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein
links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional
machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein
that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript
variants of this gene. (provided by RefSeq, May 2013)

GeneCards Summary for TADA3 Gene: 
TADA3 (transcriptional adaptor 3) is a protein-coding gene. Diseases associated with TADA3 include epicondylitis, and rectal prolapse, and among its related super-pathways are Transcription Ligand-Dependent Transcription of Retinoid-Target genes and Signal transduction Activin A signaling regulation. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and protein domain specific binding.

UniProtKB/Swiss-Prot: TADA3_HUMAN, O75528
Function: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating
histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA
complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC
complex, a complex with histone acetyltransferase activity on histones H3 and H4

Gene Wiki entry for TADA3 (TADA3L) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TADA3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTADA3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TADA3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TADA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3   Ensembl cytogenetic band:  3p25.3   HGNC cytogenetic band: 3p25.3

TADA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TADA3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M009797:  view genomic region     (about GC identifiers)

Start:
9,821,544 bp from pter      End:
9,834,695 bp from pter
Size:
13,152 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TADA3_HUMAN, O75528 (See protein sequence)
Recommended Name: Transcriptional adapter 3  
Size: 432 amino acids; 48902 Da
Subunit: The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5, TAF5L, TAF6,
TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and
SPT3. Interacts directly with TADA2L and PCAF and also with the high-risk HPV oncoprotein E6. Component of the
STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L,
TAD1L, TAF10, TAF12, TRRAP and TAF9. Component of the TFTC-HAT complex. Component of the ADA2A-containing complex
(ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1
Subcellular location: Nucleus
Secondary accessions: Q6FI83 Q9UFS2
Alternative splicing: 2 isoforms:  O75528-1   O75528-2   

Explore the universe of human proteins at neXtProt for TADA3: NX_O75528

Explore proteomics data for TADA3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75528

  • TADA3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TADA3 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001265199.1  NP_006345.1  NP_597814.1  

    ENSEMBL proteins: 
     ENSP00000307684   ENSP00000393471   ENSP00000343649   ENSP00000395073  

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    Cloud-Clone Corp. Proteins for TADA3 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--
    GO:0005634nucleus IDA--
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IDA18838386
    GO:0005730NOT nucleolus IDA--
    GO:0030914STAGA complex IDA11564863

    TADA3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019340 Histone_AcTrfase_su3

    Graphical View of Domain Structure for InterPro Entry O75528

    ProtoNet protein and cluster: O75528

    UniProtKB/Swiss-Prot: TADA3_HUMAN, O75528
    Similarity: Belongs to the NGG1 family


    TADA3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TADA3_HUMAN, O75528
    Function: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating
    histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA
    complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC
    complex, a complex with histone acetyltransferase activity on histones H3 and H4

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9674425
    GO:0003713transcription coactivator activity IDA11564863
    GO:0004402contributes to histone acetyltransferase activity IDA11564863
    GO:0005515protein binding IPI15383276
    GO:0016922ligand-dependent nuclear receptor binding IPI--
         
    TADA3 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tada3):
     cellular  embryogenesis  mortality/aging  normal 

    TADA3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tada3tm1.2Viba for TADA3

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    SwitchGear 3'UTR luciferase reporter plasmidTADA3 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TADA3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes1.00
    2Signal transduction Activin A signaling regulation
    Histone modification0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for TADA3
        Histone modification
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    1 GeneGo (Thomson Reuters) Pathway for TADA3
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes



    TADA3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TADA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/77 Interacting proteins for TADA3 (O755281, 2, 3 ENSP000003076844) via UniProtKB, MINT, STRING, and/or I2D (see all 77)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIAS4Q8N2W91, 2, 3, ENSP000002629714EBI-473249,EBI-473160 MINT-3979381 MINT-3981642 I2D: score=5 STRING: ENSP00000262971
    USP5P459741, 2, 3, ENSP000002292684EBI-473249,EBI-741277 MINT-68333 I2D: score=5 STRING: ENSP00000229268
    FAM107BQ9H0982, 3, ENSP000001817964MINT-63210 I2D: score=3 STRING: ENSP00000181796
    XRCC6P129562, 3, ENSP000003522574MINT-3979364 I2D: score=3 STRING: ENSP00000352257
    HSPA8P111422, 3MINT-63208 I2D: score=5 
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001932regulation of protein phosphorylation IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS9674425
    GO:0007067mitosis IEA--
    GO:0010628positive regulation of gene expression IMP--

    TADA3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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    About This Section

    REFSEQ mRNAs for TADA3 gene (4 alternative transcripts): 
    NM_001278270.1  NM_006354.3  NM_133480.2  NM_133481.1  

    Unigene Cluster for TADA3:

    Transcriptional adaptor 3
    Hs.386390  [show with all ESTs]
    Unigene Representative Sequence: BC009240
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000301964(uc003bsx.1 uc010hcn.1) ENST00000492103(uc003bsw.1)
    ENST00000440161 ENST00000343450(uc003bsy.3) ENST00000492635 ENST00000439043

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    Additional mRNA sequence: 

    AF069733.1 AK000228.1 AK024982.1 AK292264.1 BC001480.2 BC009240.2 BC013433.1 CR533543.1 

    20 DOTS entries:

    DT.416860  DT.100839926  DT.100839921  DT.100839923  DT.92024454  DT.100031477  DT.99993097  DT.100839925 
    DT.120858226  DT.120858314  DT.100839909  DT.100839917  DT.95267308  DT.100656916  DT.100839913  DT.100839920 
    DT.40252140  DT.95267313  DT.40120060  DT.449750 

    24/647 AceView cDNA sequences (see all 647):

    BU526470 CR607832 AL560299 BM451656 BU607466 BG031669 CD370744 BP872848 
    AI251889 AA301849 BU528048 AA365983 BI772076 BQ276507 CB216492 CR607002 
    BM550427 AI962226 BG490381 AW518352 BI259284 BG576239 NM_133481 BQ937297 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TADA3 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b
    SP1:                                                                                      -                                                   
    SP2:                                                                                      -           -     -                                 
    SP3:                    -     -                                                                                                               
    SP4:                                                                                                                                          
    SP5:        -     -     -     -     -                                                                                                         


    ECgene alternative splicing isoforms for TADA3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TADA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGCCCGGC
    TADA3 Expression
    About this image


    See TADA3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TADA3

    SOURCE GeneReport for Unigene cluster: Hs.386390

    UniProtKB/Swiss-Prot: TADA3_HUMAN, O75528
    Tissue specificity: Ubiquitously expressed

        SABiosciences Expression via Pathway-Focused PCR Array including TADA3: 
              p53 Signaling Pathway in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TADA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TADA3 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tada31 , 5 transcriptional adaptor 31, 5 90.35(n)1
    99.31(a)1
      6 (52.75 cM)5
    1012061  NM_133932.21  NP_598693.11 
     1133660255 
    chicken
    (Gallus gallus)
    Aves TADA31 transcriptional adaptor 3 83.72(n)
    92.82(a)
      416050  XM_414389.3  XP_414389.2 
    lizard
    (Anolis carolinensis)
    Reptilia TADA36
    Uncharacterized protein
    92(a)
    1 ↔ 1
    2(191263694-191271315)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC643742 hypothetical protein MGC64374 79.42(n)    BC056843.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa03f042 wufa03f04 75.7(n)   334785  BC055157.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta dik1 diskette 48.48(n)
    36.29(a)
      32787  NM_078671.4  NP_523395.1 


    ENSEMBL Gene Tree for TADA3 (if available)
    TreeFam Gene Tree for TADA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/278 SNPs in TADA3 are shown (see all 278)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822052021,2
    --9821160(+) TGTGGA/GGGGCA 1 -- ds50010--------
    rs1397149211,2
    --9821163(+) GGAGGA/GCAGTG 1 -- ds50010--------
    rs1868526831,2
    --9821391(+) GCTAAC/TCGTGA 1 -- ds50010--------
    rs1497714471,2
    --9821392(+) CTAACA/CGTGAA 1 -- ds50010--------
    rs1918413481,2
    --9821482(+) TGTTAC/TGTGCA 1 -- ds50010--------
    rs767632401,2
    C,F--9821555(+) GTGGCC/TATGGG 1 -- ds50011Minor allele frequency- T:0.06EA 120
    rs1828165101,2
    --9821580(+) GCATAC/TCCCCC 1 -- ds50010--------
    rs1888015341,2
    --9821666(+) AAACCA/TCAGCA 1 -- ut310--------
    rs1485819211,2
    C--9821764(+) GGATGA/GTAAAG 1 -- ut310--------
    rs1444766151,2
    --9821817(+) ATCTCA/GGGGAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TADA3 (9821544 - 9834695 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TADA3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834615CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602945    OMIM disorders: --

    12 diseases for TADA3:    About MalaCards
    epicondylitis    rectal prolapse    dacryoadenitis    staphyloenterotoxemia
    papilloma    retinal degeneration    retinitis    cervicitis
    acute lymphoblastic leukemia    lymphoblastic leukemia    breast cancer    leukemia

    2 diseases from the University of Copenhagen DISEASES database for TADA3:
    Staphyloenterotoxemia     Epicondylitis

    TADA3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TADA3
    Human Genome Epidemiology (HuGE) Navigator: TADA3 (3 documents)

    Export disorders for TADA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TADA3 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with TADA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hADA3 is required for p53 activity. (PubMed id 11707411)1, 2, 3 Wang T.... Brachmann R.K. (2001)
    2. Histone-like TAFs within the PCAF histone acetylase complex. (PubMed id 9674425)1, 2, 3 Ogryzko V.V.... Nakatani Y. (1998)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3. (PubMed id 12138191)1, 2 Kumar A.... Band V. (2002)
    7. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo. (PubMed id 11564863)1, 2 Martinez E.... Roeder R.G. (2001)
    8. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    9. The TAFs in the HAT. (PubMed id 9674419)1, 2 Struhl K. and Moqtaderi Z. (1998)
    10. Human ADA3 binds to estrogen receptor (ER) and functions as a coactivator for ER-mediated transactivation. (PubMed id 15496419)1, 9 Meng G....Band V. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10474 HGNC: 19422 AceView: CAMK1andTADA3L Ensembl:ENSG00000171148 euGenes: HUgn10474
    ECgene: TADA3 H-InvDB: TADA3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TADA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TADA3 gene:
    Search GeneIP for patents involving TADA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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