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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TADA2A Gene

protein-coding   GIFtS: 58
GCID: GC17P035767

Transcriptional Adaptor 2A

(Previous names: transcriptional adaptor 2 (ADA2 homolog, yeast)-like)
(Previous symbol: TADA2L)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcriptional Adaptor 2A1 2     ADA22
TADA2L1 2 3 5     hADA22
ADA2-Like Protein2 3     Transcriptional Adapter 2-Alpha2
ADA2A2 5     Transcriptional Adaptor 2 Alpha2
Transcriptional Adaptor 2 (ADA2 Homolog, Yeast)-Like1     Transcriptional Adapter 2-Like3

External Ids:    HGNC: 115311   Entrez Gene: 68712   Ensembl: ENSG000001082647   OMIM: 6022765   UniProtKB: O754783   

Export aliases for TADA2A gene to outside databases

Previous GC identifers: GC17P032842 GC17P031705


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TADA2A Gene:
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene
transcription by interacting functionally with the general transcription machinery bound at the basal promoter.
Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes,
thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional
activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively
spliced transcript variants encoding different isoforms of this gene have been described, but the full-length
nature of some of these variants has not been determined. (provided by RefSeq, Oct 2009)

GeneCards Summary for TADA2A Gene: 
TADA2A (transcriptional adaptor 2A) is a protein-coding gene. Diseases associated with TADA2A include tuberculous empyema, and pleural tuberculosis, and among its related super-pathways are Transcription Ligand-Dependent Transcription of Retinoid-Target genes. GO annotations related to this gene include histone acetyltransferase activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TADA2B.

UniProtKB/Swiss-Prot: TAD2A_HUMAN, O75478
Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Required for the function of some acidic activation domains, which activate transcription from a distant site (By
similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring
nucleosomes. Plays a role in chromatin remodeling

Gene Wiki entry for TADA2A (TADA2L) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TADA2A
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTADA2A promoter sequence
   Search SABiosciences Chromatin IP Primers for TADA2A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TADA2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12-q21   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12-q21

TADA2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TADA2A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P035767:  view genomic region     (about GC identifiers)

Start:
35,766,965 bp from pter      End:
35,839,835 bp from pter
Size:
72,871 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TAD2A_HUMAN, O75478 (See protein sequence)
Recommended Name: Transcriptional adapter 2-alpha  
Size: 443 amino acids; 51506 Da
Subunit: Interacts with GCN5 and NR3C1. Associated with the P/CAF protein in the PCAF complex. Component of the
PCAF complex, at least composed of TADA2L/ADA2, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30,
TAF12/TAFII20, TAF9/TAFII31 and TRRAP. Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP,
KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1
Subcellular location: Nucleus. Chromosome
1 PDB 3D structure from and Proteopedia for TADA2A:
1X41 (3D)    
Secondary accessions: A8MVD0 B3KMU9 Q9BVJ0 Q9UCW2 Q9UP49
Alternative splicing: 2 isoforms:  O75478-1   O75478-2   

Explore the universe of human proteins at neXtProt for TADA2A: NX_O75478

Explore proteomics data for TADA2A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75478

  • TADA2A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TADA2A Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001159577.1  NP_001479.3  NP_597683.2  

    ENSEMBL proteins: 
     ENSP00000377918   ENSP00000465521   ENSP00000465580   ENSP00000432503   ENSP00000466884  
     ENSP00000225396   ENSP00000468136   ENSP00000466468   ENSP00000465358   ENSP00000406699  

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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000125PCAF complex IDA9674425
    GO:0005634nucleus TAS8552087
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IEA--
    GO:0005694chromosome IEA--
    GO:0072686mitotic spindle IEA--

    TADA2A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR017884 SANT_dom
     IPR001005 SANT/Myb
     IPR016827 Transcriptional_adaptor_2
     IPR009057 Homeodomain-like
     IPR007526 SWIRM

    Graphical View of Domain Structure for InterPro Entry O75478

    ProtoNet protein and cluster: O75478

    2 Blocks protein domains:
    IPB000433 Zn-finger
    IPB007526 SWIRM


    UniProtKB/Swiss-Prot: TAD2A_HUMAN, O75478
    Similarity: Contains 1 SANT domain
    Similarity: Contains 1 SWIRM domain


    TADA2A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TAD2A_HUMAN, O75478
    Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
    Required for the function of some acidic activation domains, which activate transcription from a distant site (By
    similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring
    nucleosomes. Plays a role in chromatin remodeling

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8552087
    GO:0003712transcription cofactor activity TAS8552087
    GO:0004402contributes to histone acetyltransferase activity IDA9674425
         
    TADA2A for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TADA2A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes1.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for TADA2A
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    1 GeneGo (Thomson Reuters) Pathway for TADA2A
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes




    TADA2A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TADA2A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/277 Interacting proteins for TADA2A (O754782, 3 ENSP000002253964) via UniProtKB, MINT, STRING, and/or I2D (see all 277)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KAT2AQ928302, 3, ENSP000002259164MINT-8012377 MINT-8012402 MINT-7985641 I2D: score=3 STRING: ENSP00000225916
    MED1Q156482, 3, ENSP000003006514MINT-7985641 I2D: score=1 STRING: ENSP00000300651
    ENSG00000233049O602313, ENSP000004089564I2D: score=1 STRING: ENSP00000408956
    DDX39BQ138383I2D: score=1 
    DHX16O602313I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001932regulation of protein phosphorylation IEA--
    GO:0006366transcription from RNA polymerase II promoter TAS8552087
    GO:0007067mitosis IEA--
    GO:0031063regulation of histone deacetylation IEA--
    GO:0031647regulation of protein stability IEA--

    TADA2A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for TADA2A (TAD2A)

    Search CenterWatch for drugs/clinical trials and news about TADA2A / TAD2A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TADA2A gene (3 alternative transcripts): 
    NM_001166105.1  NM_001488.3  NM_133439.2  

    Unigene Cluster for TADA2A:

    Transcriptional adaptor 2A
    Hs.500066  [show with all ESTs]
    Unigene Representative Sequence: AK225918
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394395(uc002hnt.3 uc002hnw.3) ENST00000585341 ENST00000589153
    ENST00000587420 ENST00000490992(uc002hnv.3) ENST00000587211 ENST00000586023
    ENST00000225396 ENST00000590005 ENST00000590957 ENST00000589849 ENST00000591992
    ENST00000587593 ENST00000591933 ENST00000591335 ENST00000588405 ENST00000417170(uc002hnu.1)

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    Additional mRNA sequence: 

    AF064094.1 AF069732.1 AK022767.1 AK096371.1 AK225918.1 BC001172.1 BC011753.2 

    15 DOTS entries:

    DT.40311061  DT.100652497  DT.100023091  DT.100023092  DT.100724658  DT.429448  DT.100654330  DT.439866 
    DT.95273699  DT.100774204  DT.120931017  DT.91759608  DT.91811353  DT.95105280  DT.120930924 

    24/112 AceView cDNA sequences (see all 112):

    AL526501 BI333991 AA856985 CF529493 BC011753 AW298572 CB215685 AI968140 
    BX370711 BQ068240 AA297862 BQ187943 R74011 AI000805 AA809900 AI220840 
    CR615572 AF069732 BP377907 BI825287 BI910656 BI916525 CD639067 BQ900440 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TADA2A (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^
    SP1:                                                  -     -                                   -                 -                                             
    SP2:                                                                                            -                 -                                             
    SP3:                                                  -     -                                   -                                                               
    SP4:        -     -                                         -                                                                                                   
    SP5:        -     -                                                                                                                                             

    ExUns: 19
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for TADA2A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TADA2A expression in normal human tissues (normalized intensities)      TADA2A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCTGTTAT
    TADA2A Expression
    About this image


    TADA2A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Ovary (Reproductive System)
             Secondary Oocyte Antral Follicle
     
     Gonad
             Secondary Oocyte Antral Follicle

    See TADA2A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TADA2A

    SOURCE GeneReport for Unigene cluster: Hs.500066

    UniProtKB/Swiss-Prot: TAD2A_HUMAN, O75478
    Tissue specificity: Expressed in all tissues, but most abundantly in testis

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TADA2A gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tada2a1 , 5 transcriptional adaptor 2A1, 5 90.72(n)1
    97.29(a)1
      11 (51.29 cM)5
    2170311  NM_172562.31  NP_766150.11 
     840789205 
    chicken
    (Gallus gallus)
    Aves TADA2A1 transcriptional adaptor 2A 81.07(n)
    90.72(a)
      417656  NM_001012807.1  NP_001012825.1 
    lizard
    (Anolis carolinensis)
    Reptilia TADA2A6
    Uncharacterized protein
    90(a)
    1 ↔ 1
    GL343439.1(51716-67542)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.106062 Transcribed sequence with moderate similarity to protein more 78.47(n)    141995457 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.126572 Transcribed sequence with moderate similarity to protein more 74.56(n)    BM141440.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rpb41 CG33520-PA 44.23(n)
    38.66(a)
      326128  NM_001014636.2  NP_001014636.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ADA2(YDR448W)4
    ADA21
    Transcription coactivator, component of the ADA and more4
    Ada2p1
    44.44(n)1
    31.89(a)1
      4(1356065-1357369)4
    8520591, 4  NP_010736.31  NP_010736.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ADA2B1 transcriptional adapter ADA2b 46.08(n)
    33.85(a)
      827336  NM_202832.2  NP_974561.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g07508001 hypothetical protein 46.02(n)
    33.81(a)
      4334126  NM_001057822.1  NP_001051287.1 


    ENSEMBL Gene Tree for TADA2A (if available)
    TreeFam Gene Tree for TADA2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TADA2A gene
    TADA2B2  
    1 SIMAP similar gene for TADA2A using alignment to 6 protein entries:     TAD2A_HUMAN (see all proteins):
    TADA2B

    TADA2A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1427 SNPs in TADA2A are shown (see all 1427)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs795231581,2
    --35768920(+) GACCTA/CCCCCA 3 -- int10--------
    rs571077031,2
    C--35768926(+) CCCCAC/ACCCAA 3 -- int12Minor allele frequency- A:0.06WA 120
    rs1846213001,2
    --35769084(+) TTAGTC/TCACTA 3 -- int10--------
    rs118712751,2
    C,F,H--35769089(+) CCACTA/TCTATG 3 -- int118Minor allele frequency- T:0.18NS EA NA WA CSA 936
    rs112637481,2
    C,H--35769211(+) ACTGTC/TGCCCA 3 -- int18Minor allele frequency- T:0.06NA CSA 17
    rs1875290581,2
    --35769253(+) CTGCAA/GCCTCC 3 -- int10--------
    rs1426935581,2
    --35769322(+) CGCCCA/GCCACC 3 -- int10--------
    rs1920425821,2
    --35769383(+) GTTGCC/TCAGGC 3 -- int10--------
    rs1841910001,2
    --35769555(+) GCCAGA/GTAAAA 3 -- int10--------
    rs1507304721,2
    C--35769726(+) GCCCGC/TGCCTG 3 -- int10--------

    HapMap Linkage Disequilibrium report for TADA2A (35766965 - 35839835 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for TADA2A:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv550e199CNV Deletion23128226
    esv2715889CNV Deletion23290073
    dgv549e199CNV Deletion23128226
    nsv435684CNV Deletion17901297
    esv2661747CNV Deletion23128226
    dgv524n67CNV Loss20364138
    nsv9543CNV Loss18304495
    esv1010097CNV Gain20482838
    dgv955e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602276    OMIM disorders: --

    11 diseases for TADA2A:    About MalaCards
    tuberculous empyema    pleural tuberculosis    congenital diaphragmatic hernia    hernia
    retinal degeneration    retinitis    acute lymphoblastic leukemia    lymphoblastic leukemia
    tuberculosis    thyroiditis    leukemia

    1 disease from the University of Copenhagen DISEASES database for TADA2A:
    Congenital diaphragmatic hernia

    TADA2A for disorders           About GeneDecksing

    Genetic Association Database (GAD): TADA2A
    Human Genome Epidemiology (HuGE) Navigator: TADA2A (1 document)

    Export disorders for TADA2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TADA2A gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with TADA2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. (PubMed id 8552087)1, 2, 3 Candau R....Berger S.L. (1996)
    2. Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor. (PubMed id 9154805)1, 2, 9 Henriksson A....Wright A.P.H. (1997)
    3. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Histone-like TAFs within the PCAF histone acetylase complex. (PubMed id 9674425)1, 2 Ogryzko V.V.... Nakatani Y. (1998)
    7. The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily. (PubMed id 9885574)1, 2 Vassilev A....Nakatani Y. (1998)
    8. A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. (PubMed id 12972612)1, 9 Barlev N.A.... Berger S.L. (2003)
    9. Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors. (PubMed id 9649342)1, 9 Almlof T....Wright A.P. (1998)
    10. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6871 HGNC: 11531 AceView: TADA2L Ensembl:ENSG00000108264 euGenes: HUgn6871
    ECgene: TADA2A H-InvDB: TADA2A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TADA2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TADA2A gene:
    Search GeneIP for patents involving TADA2A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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