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Aliases & Descriptions for TADA1L
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| OTTHUMP00000032213 2 | | RP1-9E21.4 2 | | STAF42 1, 2, 3, 5 |
| | | Descriptions |
|---|
| SPT3-associated factor 42 3 | | SPT3-associated factor 42 (STAF42) 2 | | transcriptional adaptor 1 (HFI1 homolog, yeast)-like 2 | | transcriptional adaptor 1-like 2 |
|
| | Search outside databases for aliases for TADA1L genePrevious GC identifer: GC01M163558 |
Summaries for TADA1L(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for TADA1L: TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM] UniProtKB/Swiss-Prot: TAD1L_HUMAN, Q96BN2Function: Probably involved in transcriptional regulation |
Genomic Location for TADA1L
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the TADA1L gene 
Entrez Gene cytogenetic band: 1q24.1 Ensembl cytogenetic band: 1q24.1 HGNC cytogenetic band: 1q24.1TADA1L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M165092:
(about GC identifiers)
Start:
|
165,092,371 bp from pter |
End:
|
165,112,103 bp from pter |
Size:
|
19,733 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000001.9 NT_004487.18
| Proteins for TADA1L
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: TAD1L_HUMAN, Q96BN2 (See
protein sequence)Recommended Name: Transcriptional adapter 1-like protein Size: 335 amino acids; 37382 Da
Subunit: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9
Subcellular location: NucleusREFSEQ proteins: NP_444281.1
ENSEMBL proteins: ENSP00000356848
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- | About this table
Antibodies for TADA1L: Assays for TADA1L: | Protein
Domains/ Families for TADA1L(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96BN2 UniProtKB/Swiss-Prot: TAD1L_HUMAN, Q96BN2Similarity: Belongs to the TADA1L family | Gene Function for TADA1L
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_053053
Applied Biosystems Silencer® siRNAs for TADA1L
Sigma-Aldrich siRNA for TADA1L  Sigma-Aldrich shRNA for TADA1L  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_053053                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_053053                                  untagged cDNA clones in CMV expression vector (see all 2): NM_053053 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_053053
UniProtKB/Swiss-Prot: TAD1L_HUMAN, Q96BN2Function: Probably involved in transcriptional regulation | Pathways & Interactions for TADA1L
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| --2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006350 | transcription |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | About this table
|
Drugs & Compounds for TADA1L(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for TADA1L
|
Transcripts for TADA1L(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_053053
Sigma-Aldrich siRNA for TADA1L  Sigma-Aldrich shRNA for TADA1L  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_053053 REFSEQ mRNAs for TADA1L gene: NM_053053.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_053053               OriGene GFP tagged cDNA clone in CMV expression vector: NM_053053                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_053053                                  untagged cDNA clones in CMV expression vector (see all 2): NM_053053  Additional cDNA sequence: AK097234.1 AK290964.1 AK291922.1 AK309250.1 AK310391.1 BC015401.2 BC036497.1 CR618254.1 CR619512.1 9 DOTS entries: DT.100021883 DT.95072415 DT.435782 DT.95271895 DT.100712859 DT.121329968 DT.40197294 DT.95319337 DT.121329971 24/149 AceView cDNA sequences (see all 149
):R23855 BQ007595 CR618254 AI638273 F02843 AI091145 BU506795 BQ692025 BC015401 AV695196 CB215701 BG530033 T32678 AW006271 CB156261 BM802734 Z40141 AI620275 CA487312 AL521142 BM465890 BQ433949 NM_053053 BQ686349
highest scoring ESTs for TADA1L:AL703168 AL703355 AV647292 AV760041 BC015401 BE165279 BF338443 BF528015 BF665270 BF976915 Unigene Cluster for TADA1L: Transcriptional adaptor 1 (HFI1 homolog, yeast)-like Hs.435967 [show with all ESTs]Unigene Representative Sequence: BC036497
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for TADA1L
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | |
| SP1: | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for TADA1L
1 Ensembl transcript including schematic representation: ENST00000367874
|
Expression for TADA1L
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| TADA1L expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for TADA1L
1 / 2 / 3 3 probe-sets matching TADA1L gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: ACTCAAGTTT
SOURCE GeneReport for Unigene cluster: Hs.435967
|
Orthologs for TADA1L
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for TADA1L gene from 5/11 species (see all 11
)
About this table Species with no ortholog for TADA1L
ENSEMBL Gene Tree for TADA1L | Paralogs for TADA1L(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Pseudogenes
- 1 related pseudogene
|
SNPs/Variants for TADA1L(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for TADA1L (up to first 250kb)
|
Disorders & Mutations for TADA1L
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 612763
Human Genome Epidemiology Navigator: TADA1L (1 document)
|
Medical News for TADA1L(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for TADA1L (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 8 PubMed articles for TADA1L gene: |
Search for TADA1L
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TADA1L
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing TADA1L
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TADA1L(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for TADA1L(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for TADA1L:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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