TACSTD2 Gene

Aliases
for TACSTD2 gene

Previous GC identifers: GC01M058957 GC01M057955 GC01M058398 GC01M058411 GC01M058412 GC01M058752 GC01M058813 GC01M057151

Summaries
for TACSTD2 gene

Genomic Views
for TACSTD2 gene

RefSeq DNA sequence:

NC_000001.10  NC_018912.1  NT_032977.9  

SwitchGear Promoter luciferase reporter plasmids (see all 2): TACSTD2 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TACSTD2

TACSTD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M059041:  view genomic region     (about GC identifiers)

Proteins
for TACSTD2 gene

Explore the universe of human proteins at neXtProt for TACSTD2: NX_P09758

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for TACSTD2 (TROP-2)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: TACSTD2 OriGene Protein Over-expression Lysate: TACSTD2 OriGene Custom Protein Services for TACSTD2
	GenScript Custom Purified and Recombinant Proteins Services for TACSTD2
	Novus Biologicals TACSTD2 Proteins Novus Biologicals TACSTD2 Lysate
	Sino Biological Recombinant Protein for TACSTD2
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TACSTD2

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for TACSTD2 (TROP-2)
	OriGene Antibodies (see all 2): TACSTD2 OriGene Custom Antibody Services for TACSTD2
	GenScript Custom Superior Antibodies Services for TACSTD2
	Novus Biologicals TACSTD2 Antibodies
	Search for Antibodies for TACSTD2 at Abcam
	Uscn Antibodies for TACSTD2
	ThermoFisher Antibodies for TACSTD2

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	R&D Systems Multiplex/Array Assay Kits & Reagents for TACSTD2 (TROP-2)
	GenScript Custom Assay Services for TACSTD2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for TACSTD2

Protein Domains /
Families
for TACSTD2 gene

ProtoNet protein and cluster: P09758

Function
for TACSTD2 gene

miRNA Products:		miRTarBase miRNAs that target TACSTD2: hsa-mir-155 (MIRT001496)
		OriGene 3'-UTR Clone: TACSTD2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TACSTD2
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate TACSTD2:
		hsa-miR-877* hsa-miR-550a hsa-miR-495 hsa-miR-520d-5p hsa-miR-524-5p
		SwitchGear 3'UTR luciferase reporter plasmid: TACSTD2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TACSTD2 (see all 7) OriGene shRNA RFP: TACSTD2 OriGene siRNA: TACSTD2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TACSTD2

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for TACSTD2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TACSTD2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TACSTD2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TACSTD2 (NM_002353)
		Sino Biological Human cDNA Clone for TACSTD2
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TACSTD2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TACSTD2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TACSTD2
		Search LifeMap BioReagents cell lines for TACSTD2

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TACSTD2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

(inferred from 1 allele) (MGI details for Tacstd2)

Pathways & Interactions
for TACSTD2 gene

Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

Drugs & Compounds
for TACSTD2 gene

Transcripts
for TACSTD2 gene

Expression
for TACSTD2 gene

TACSTD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTACCCGA

6 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	KidneyUreteric BudUreteric Bud Cells			Kidney
	KidneyUreteric BudUreteric Bud Tip Cells			Kidney
	TestisSeminiferous TubulesSertoli cells			Testis
	KidneyRenal Collecting Duct System			Kidney
	Lower Urinary TractUreter			Lower Urinary Tract
	Reproductive SystemVas Deferens			Reproductive System
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 6 LifeMap Cells
	Name			Category
	PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)			Endothelium
	PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)			Endothelium
	PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)			Endothelium
	PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)			Adipose, Bone, Cartilage
	PureStem™ progenitor E44 (Embryonic Progenitor Cell)
	HyStem+TGF?3+GDF5-induced E15 cells (HyStem+TGF?3+GDF5 in...)			Bone, Cartilage

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TACSTD2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TACSTD2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TACSTD2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TACSTD2

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TACSTD2

Orthologs
for TACSTD2 gene

Paralogs
for TACSTD2 gene

Paralogs for TACSTD2 gene

EPCAM²  

1 SIMAP similar gene for TACSTD2 using alignment to 3 protein entries:     TACD2_HUMAN (see all proteins):

EPCAM

TACSTD2 for paralogs           About GeneDecksing

Genomic Variants
for TACSTD2 gene

10/128 NCBI SNPs in TACSTD2 are shown (see all 128)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs766905761,2		--	57151366(+)	GGTGAT/CAAGCC	1	--	ds5001		1		WA	118
rs95831,2	C,F,H,	--	57152011(-)	ATTTGA/GTGAGT	1	--	ut31		17		MN NS EA NA WA	2262
rs1162507711,2	C,F,	--	57152026(+)	TAAACC/TCAAGG	1	--	ut31		1		WA	118
rs413133651,2		--	57152036(+)	GCGATA/GACAAC	1	--	ut31		0	--	--	--	--
rs800126551,2	C,F,	--	57152206(+)	GAAAGG/TGGATA	1	--	ut31		1		WA	118
rs413133631,2	C,F,	--	57152230(+)	NNNNCA/C/TTCAAG	2	--	ut31		8		NA WA CSA EA	367
rs73550421,2	C,F,	--	57152266(+)	CTGAGG/ACCAGG	1	--	ut31 ese3		1		WA	118
rs726722951,2	C,	--	57152334(+)	TAAACA/GTCTCC	1	--	ut31		0	--	--	--	--
rs2328351,2	C,F,A,	--	57153457(-)	CCCCGA/CCGAGT	1	--	ut51 ese3		8		EA NA WA CSA	383
rs617792941,2	C,	--	57153572(+)	GTCCCC/TACTGG	1	--	ut51		3		NA WA	240

HapMap Linkage Disequilibrium report for TACSTD2 (59041095 - 59043166 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for TACSTD2: --
Human Gene Mutation Database (HGMD): TACSTD2

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TACSTD2

DNA2.0 Custom Variant and Variant Library Synthesis for TACSTD2

Disorders / Diseases
for TACSTD2 gene

20/24 diseases for TACSTD2

9 Novoseek disease relationships for TACSTD2 gene    About this table

Publications
for TACSTD2 gene

PubMed articles for TACSTD2 gene, integrated from 9 sources (see all 81): (articles sorted by number of sources associating them with TACSTD2)

Utopia: connect your pdf to the dynamic world of online information

1. Retroposition in a family of carcinoma-associated antigen genes. (PubMed id 8382772)^{1, 2, 3, 9} Linnenbach A.J.... Huebner K. (1993)
2. A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy. (PubMed id 11687514)^{1, 2, 9} Tasa G.... Lang A. (2001)
3. Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. (PubMed id 7665234)^{1, 2, 9} Fornaro M.... Alberti S. (1995)
4. Compound heterozygous mutations of M1S1 gene in gelatinous droplike corneal dystrophy. (PubMed id 15013888)^{1, 4, 9} Tian X....Liu Z. (2004)
5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
6. Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization. (PubMed id 11306819)^{1, 3} Calabrese G....Alberti S. (2001)
7. Identification of the gene responsible for gelatinous drop-like corneal dystrophy. (PubMed id 10192395)^{1, 2} Tsujikawa M.... Nakamura Y. (1999)
8. Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733. (PubMed id 2911574)^{1, 2} Linnenbach A.J.... Koprowski H. (1989)
9. Four mutations (three novel, one founder) in TACSTD2 among Iranian GDLD patients. (PubMed id 17898270)^{1, 9} Alavi A....Amini S.S. (2007)
10. Detection of mRNAs of GA733 genes by RT-PCR in exfoliated cells of pleural and peritoneal effusions and its clinical values. (PubMed id 17878632)^{1, 9} Zhang K.H....Lv N.H. (2007)

External Searches for TACSTD2 gene

Genome Databases showing TACSTD2 gene

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Specialized Databases showing TACSTD2 gene

Products
for TACSTD2 gene