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TACR2 Gene

protein-coding GIFtS: 62

GC10M070834

tachykinin receptor 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: TAC2R, NKNAR)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
NK-2R ^³
NK2R ^¹, ², ³
NKNAR ^², ³, ⁵
OTTHUMP00000019722 ^²
SKR ^¹, ², ³
TAC2R ^², ³, ⁵

Descriptions
NK-2 receptor ^², ³
Neurokinin A receptor ^², ³
neurokinin 2 receptor ^²
seven transmembrane helix receptor ^²
substance K receptor ^²
tachykinin receptor 2 ^², ³

External Ids
HGNC: 11527¹
Entrez Gene: 6865²
UniProtKB: P21452³
Ensembl: ENSG00000075073⁷

Search outside databases for aliases for TACR2 gene

Previous GC identifers: GC10M069975 GC10M070250 GC10M071056 GC10M070509

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TACR2:

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor

affinities are specified by variations in the 5'-end of the sequence. The receptors belonging

to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane

regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred

to as neurokinin A. [provided by RefSeq]

UniProtKB/Swiss-Prot: NK2R_HUMAN, P21452

Function: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is

associated with G proteins that activate a phosphatidylinositol-calcium second messenger system

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TACR2 gene

Entrez Gene cytogenetic band: 10q11-q21 Ensembl cytogenetic band: 10q21.3 HGNC cytogenetic band: 10pter-q23

TACR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M070834: (about GC identifiers)

Start:	70,833,665 bp from pter
End:	70,846,680 bp from pter
Size:	13,016 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000010.9 NT_008583.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: NK2R_HUMAN, P21452 (See protein sequence)

Recommended Name: Substance-K receptor

Size: 398 amino acids; 44442 Da

Subcellular location: Cell membrane; Multi-pass membrane protein

Miscellaneous: The rank order of affinity of this receptor to tachykinins is: substance K >

neuromedin-K > substance P

Secondary accessions: Q8NGQ8 Q9UDE7

REFSEQ proteins: NP_001048.2

ENSEMBL proteins:

ENSP00000362403 ENSP00000362404

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant TACR2 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Neurokinin A Receptor)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	2173708

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Antibodies for TACR2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of TACR2
	Sigma-Aldrich Antibodies for TACR2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Neurokinin A Receptor), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TACR2)
	Novus Biologicals Antibodies for TACR2

Assays for TACR2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P21452

ProtoNet protein and cluster: P21452

2 Blocks protein families:

IPB000913 Neurokinin NK2 receptor signature

IPB001681 Neurokinin receptor signature

UniProtKB/Swiss-Prot: NK2R_HUMAN, P21452

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TACR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TACR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001057

Applied Biosystems Silencer® siRNAs for TACR2

Sigma-Aldrich siRNA and siRNA Panels for TACR2

Sigma-Aldrich shRNA Panels and shRNA for TACR2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Millipore Clones for the Expression of TACR2

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001057
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001057
untagged cDNA clone in CMV expression vector: NM_001057

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001057

UniProtKB/Swiss-Prot: NK2R_HUMAN, P21452

Function: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is

associated with G proteins that activate a phosphatidylinositol-calcium second messenger system

Genatlas biochemistry entry for TACR2:

tachykinin 2 receptor,neurokinin A receptor (substance K), G protein coupled receptor superfamily

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	IEA	--
GO:0004995	tachykinin receptor activity	TAS	8307161

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for TACR2

5/13 Interacting proteins for TACR2 (ENSP00000362403³) via UniProtKB, MINT, and/or STRING (see all 13 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TAC1	ENSP00000321106³	STRING (score=.999)
TAC3	ENSP00000350236³	STRING (score=.992)
TAC4	ENSP00000334042³	STRING (score=.964)
B3GAT1	ENSP00000307875³	STRING (score=.911)
CUL1	ENSP00000326804³	STRING (score=.91)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006936	muscle contraction	TAS	2173708
GO:0007165	signal transduction	IEA	--
GO:0007217	tachykinin receptor signaling pathway	TAS	8307161
GO:0007588	excretion	TAS	10862829

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for TACR2

Sigma-Aldrich Small Molecules for TACR2:

Antagonist

Compounds for TACR2 available from Tocris Bioscience

Compound	Action	CAS number
MDL 29,913	Selective NK2 antagonist	[135721-56-1]
MEN 10376	Potent, selective NK2 antagonist	[135306-85-3]
GR 159897	Non-peptide, potent NK2 antagonist	[158848-32-9]
GR 94800	Potent, selective NK2 antagonist	[141636-65-9]
[bAla8]-Neurokinin A(4-10)	NK2 agonist	[122063-01-8]

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10/32 Novoseek chemical compound relationships for TACR2 gene (see all 32 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
senktide	91.88	12	8751080 (2), 9422808 (2), 7544197 (1), 7530573 (1) (see all 10)
cyclo(gln-trp-phe-gly-leu-met)	91.56	4	7544197 (1), 1964226 (1), 8161607 (1), 7705977 (1)
sr48968	91.38	15	12906840 (1), 15191205 (1), 9778489 (1), 10849478 (1) (see all 13)
men 10376	87.13	2	9641542 (1), 16554357 (1)
gr 71251	86.86	1	7688874 (1)
cyclo(met-asp-trp-phe-dap-leu)cyclo(2beta-5beta)	85.57	1	7737306 (1)
septide	85.57	3	7685292 (1), 9422808 (1), 7518302 (1)
fk 224	84.64	8	8665034 (2), 7543746 (1), 7889271 (1), 7531648 (1) (see all 5)
gr 82334	80.85	1	8587664 (1)
fk 888	76.66	5	8529964 (1), 16554357 (1), 7889271 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TACR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TACR2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001057

Sigma-Aldrich siRNA and siRNA Panels for TACR2

Sigma-Aldrich shRNA Panels and shRNA for TACR2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001057

REFSEQ mRNAs for TACR2 gene:

NM_001057.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001057

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001057
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001057
                                 untagged cDNA clone in CMV expression vector: NM_001057

Additional cDNA sequence:

AK096906.1 AK291996.1 AK300649.1 AY322545.1 BC033742.1 BC096842.1 M57414.1

2 DOTS entries:

DT.100642718 DT.75101841

24/32 AceView cDNA sequences (see all 32 ):

AY322545 AW080614 BF064138 AI971217 BQ020625 AW137396 BX483277 AI494107

BX483562 CF147817 BM906753 BX483631 AW134918 BC033742 AI421049 CD610397

M57414 BX280340 AW135753 BI765515 BE790440 NM_001057 BX483630 AI224121

highest scoring ESTs for TACR2:

AY322545 BC033742 BI765515 BM906753 BX483277 BX483562 BX483630 CF147817 M57414 BC096842

Unigene Cluster for TACR2:

Tachykinin receptor 2

Hs.88372 [show with all ESTs]

Unigene Representative Sequence: NM_001057

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000373306 ENST00000373307

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TACR2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TACR2

¹ / ² / ³

3 probe-sets matching TACR2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35404_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M60284	0.20	1.00	0.72	1
214348_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001057	0.60	1.00	0.82	1
214348_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGCCAGAAC

SOURCE GeneReport for Unigene cluster: Hs.88372
Expression variation in blood from EXPOLDB for TACR2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TACR2 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	Tacr2¹	--	tachykinin receptor 2	87.6(n) 87.07(a)	489020 NM_001012617.1 NP_001012635.1
chimpanzee (Pan troglodytes)	TACR2¹	--	tachykinin receptor 2	98.83(n) 98.24(a)	450506 XM_507831.2 XP_507831.2
cow (Bos taurus)	TACR2¹	--	tachykinin receptor 2	88.74(n) 88.92(a)	282088 NM_174469.2 NP_776894.1
mouse (Mus musculus)	Tacr2^{1, 5}	10⁵	tachykinin receptor 2^{1, 5}	85.05(n)¹ 85.75(a)¹	21337¹ NM_009314.3¹ NP_033340.2¹ AF399705⁵ AK033443⁵ (see all 8)
chicken (Gallus gallus)	TACR2¹	--	tachykinin receptor 2	67.82(n) 65.13(a)	768996 XM_001232176.1 XP_001232177.1

About this table Species with no ortholog for TACR2

ENSEMBL Gene Tree for TACR2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for TACR2 gene

TACR3² TACR1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/170 NCBI SNPs in TACR2 are shown (see all 170 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 81)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs5030928^1,2	A,C,F,H	70846643(-)	`GCAGCT/CGGCAG`	1	--	ut5¹ tfbs³		4	EU EA WA	400
	rs5030920^1,2	A,C,F,H	70846018(-)	`GGGCAT/CCACAG`	1	T/I	mis¹ ese³		13	EU EA WA NA	1330
	rs5030921^1,2	A,C,F,H	70847261(-)	`TTCCCG/AGAAGA`	1	--	ng3¹ tfbs³		8	EU EA WA	840
	rs7906863^1,2	A,C,F,H	70846341(+)	`ATCATG/ATGGAA`	1	--	ut5¹ ese³		8	EU EA WA	836
	rs3763737^1,2	C,F,H	70848221(+)	`GGCAGT/CGGGAA`	1	--	ng3¹		8	EA NA EU WA	1466
	rs10762295^1,2	A,F,H	70846724(+)	`TGCTCA/GCGAGG`	1	--	ng3¹		4	EU EA WA	420
	rs11595348^1,2	C,F,H	70846926(+)	`GAGTTC/GGAGCC`	1	--	ng3¹		8	EU EA WA	828
	rs12244723^1,2	C,F,H	70833733(+)	`CCCATT/CATCAT`	1	--	ng5¹ ese³		4	EU EA WA	392
	rs3793853^1,2	C,F	70846635(+)	`TCAGGG/ACTCTG`	1	--	ut5¹		1	EA	1480
	rs10998766^1,2	F,H	70846689(+)	`GCAGGG/ACCAGT`	1	--	ng3¹		4	EU EA WA	418

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HapMap Linkage Disequilibrium images for TACR2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 162321

10/14 Novoseek disease relationships for TACR2 gene (see all 14 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
asthma	41.95	10	9875470 (1), 9223001 (1), 8627566 (1), 15992015 (1) (see all 7)
airways disease	25.49	1	7891319 (1)
inflammation	21.02	8	15037522 (2), 11712745 (2), 8529964 (1), 8552786 (1) (see all 6)
erythroleukemia	7.57	2	8302285 (2)
hyperalgesia	6.54	1	15037522 (1)
tumors	0.45	3	11384204 (1), 16222150 (1), 19111017 (1)
necrosis	0.00	2	11384204 (1), 19111017 (1)
pulmonary disease chronic obstructive	0.00	1	11712745 (1)
lung diseases	0.00	1	1281723 (1)
allergic reaction	0.00	1	8821532 (1)

About this table

Human Genome Epidemiology Navigator: TACR2 (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/285 PubMed articles for TACR2 gene (see all 285 ):

Cloning and expression of the human substance K receptor and analysis of its role in mitogenesis. (PubMed id 1848773)^{1, 3, 4} Kris R.M.... Schlessinger J. (1991)
The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. (PubMed id 2173708)^{1, 3, 4} Gerard N.P.... Gerard C. (1990)
The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of the cDNA from tracheal and gastric tissues. (PubMed id 1845990)^{1, 3, 4} Gerard N.P....Gerard C. (1991)
Isolation and characterisation of the human lung NK-2 receptor gene using rapid amplification of cDNA ends. (PubMed id 1710456)^{3, 4} Graham A.... Briggs I. (1991)
Molecular cloning of the human neurokinin-2 receptor cDNA by polymerase chain reaction and isolation of the gene. (PubMed id 1659296)^{3, 4} Gerard N.P. and Gerard C. (1991)
Qualitative and quantitative analysis of tachykinin NK2 receptors in chemically defined human colonic neuronal pathways. (PubMed id 18219665)^{1, 3} Jaafari N....Jule Y. (2008)
The ligand binding site of the neurokinin 2 receptor. Site-directed mutagenesis and identification of neurokinin A binding residues in the human neurokinin 2 receptor. (PubMed id 7961636)^{1, 3} Bhogal N....Findlay J.B. (1994)
Association of genetic variations in neurokinin-2 receptor with enhanced cough sensitivity to capsaicin in chronic cough. (PubMed id 16893949)^{1, 3} Park H.K....Kim Y.Y. (2006)
Tachykinin antagonists inhibit nerve-mediated contractions in the circular muscle of the human ileum. Involvement of neurokinin-2 receptors. (PubMed id 1370160)^{1, 3} Maggi C.A....Giachetti A. (1992)
Distribution pattern of tachykinin NK2 receptors in human colon: involvement in the regulation of intestinal motility. (PubMed id 17503489)^{1, 3} Jaafari N....Jule Y. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6865	HGNC: 11527	AceView: TACR2	Ensembl:ENSG00000075073	euGenes: HUgn6865
ECgene: TACR2	H-InvDB: TACR2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for TACR2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for TACR2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TACR2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TACR2		Antibodies for TACR2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TACR2		Small molecules for TACR2
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Recombinant Proteins (Neurokinin A Receptor)
	Antibodies (Neurokinin A Receptor)

Search OriGene for TACR2

Tocris compounds for TACR2

	Drugs for TACR2
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for TACR2

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TACR2 Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for TACR2

Summaries
for TACR2

Genomic Location
for TACR2

Proteins
for TACR2

Protein Domains/
Families
for TACR2

Gene Function
for TACR2

Pathways & Interactions
for TACR2

Drugs & Compounds
for TACR2

Transcripts
for TACR2

Expression
for TACR2

Orthologs
for TACR2

Paralogs
for TACR2

SNPs/Variants
for TACR2

Disorders & Mutations
for TACR2

Medical News
for TACR2

Publications
for TACR2

Search for TACR2

Genome Databases showing TACR2

Other Databases showing TACR2

Specialized Databases showing TACR2

Licensable Technologies
for TACR2

Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TACR2 Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor TACR2

Summariesfor TACR2

Genomic Locationfor TACR2

Proteinsfor TACR2

Protein Domains/Familiesfor TACR2

Gene Functionfor TACR2

Pathways & Interactionsfor TACR2

Drugs & Compoundsfor TACR2

Transcriptsfor TACR2

Expression for TACR2

Orthologsfor TACR2

Paralogsfor TACR2

SNPs/Variantsfor TACR2

Disorders & Mutationsfor TACR2

Medical Newsfor TACR2

Publicationsfor TACR2

Search for TACR2

Genome Databases showing TACR2

Other Databases showing TACR2

Specialized Databases showing TACR2

Licensable Technologiesfor TACR2

Servicesfor TACR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TACR2

Summaries
for TACR2

Genomic Location
for TACR2

Proteins
for TACR2

Protein Domains/
Families
for TACR2

Gene Function
for TACR2

Pathways & Interactions
for TACR2

Drugs & Compounds
for TACR2

Transcripts
for TACR2

Expression
for TACR2

Orthologs
for TACR2

Paralogs
for TACR2

SNPs/Variants
for TACR2

Disorders & Mutations
for TACR2

Medical News
for TACR2

Publications
for TACR2

Licensable Technologies
for TACR2

Services
for TACR2