Aliases for TACC3 Gene
External Ids for TACC3 Gene
Previous GeneCards Identifiers for TACC3 Gene
This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011]
GeneCards Summary for TACC3 Gene
TACC3 (Transforming Acidic Coiled-Coil Containing Protein 3) is a Protein Coding gene. Diseases associated with TACC3 include gliosarcoma and giant cell glioblastoma. Among its related pathways are RNA transport and Notch Signaling Pathways. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is TACC2.
UniProtKB/Swiss-Prot for TACC3 Gene
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.