TACC1 Gene
protein-coding GIFtS: 57
GCID: GC08P038586
|
|
transforming, acidic coiled-coil containing protein 1
| |
Aliases
for TACC1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transforming, Acidic Coiled-Coil Containing Protein 11 2 | | Transforming Acidic Coiled-Coil-Containing Protein 12 | | Gastric Cancer Antigen Ga552 3 | | KIAA11033 | | Ga552 | | Taxin-13 | | Taxin-13 | | |
Export aliases for TACC1 gene to outside databasesPrevious GC identifers: GC08P038196 GC08P038859 GC08P038326 GC08P038603 GC08P038733 GC08P037121 |
Summaries
for TACC1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TACC1:
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 thatis amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for thisgene. (provided by RefSeq, Apr 2009)
UniProtKB/Swiss-Prot: TACC1_HUMAN, O75410Function: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues
Gene Wiki entry for TACC1
|
Genomic Views
for TACC1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TACC1 gene promoter:
HSF1 (long) Tal-1beta Arnt Evi-1 E47 Gfi-1 Sox9 FOXO1a HSF1short FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TACC1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TACC1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p11.22 Ensembl cytogenetic band: 8p11.22 HGNC cytogenetic band: 8p11TACC1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P038586: view genomic region
(about GC identifiers)
Start:
|
38,585,704 bp from pter |
End:
|
38,710,546 bp from pter |
Size:
|
124,843 bases |
Orientation:
|
plus strand |
|
Proteins
for TACC1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TACC1_HUMAN, O75410 (See
protein sequence)Recommended Name: Transforming acidic coiled-coil-containing protein 1 Size: 805 amino acids; 87794 Da
Subunit: Interacts with KIAA0097/CH-TOG and with the oncogenic transcription factor YEATS4. Interacts with AURKA, AURKBand AURKC. Interacts with LSM7, TDRD7 and SNRPG. Interacts with GCN5L2 and PCAF
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Nucleus during interphase. Weaklyconcentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis
Developmental stage: Expressed at high level during early embryogenesis
Secondary accessions: B2RBD9 D3DSX6 Q6Y687 Q86YG7 Q8IUJ2 Q8IUJ3 Q8IUJ4 Q8IZG2 Q8NEY7 Q9UPP9Alternative splicing: 8 isoforms: O75410-1 O75410-2 O75410-3 O75410-4 O75410-5 O75410-6 O75410-7 O75410-8 Explore the universe of human proteins at neXtProt for TACC1: NX_O75410
Post-translational modifications:
Isoform 1 is heavily phosphorylated; isoform 6 is not1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75410
TACC1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001116296.1 NP_001139688.1 NP_006274.2
ENSEMBL proteins: ENSP00000428687 ENSP00000428450 ENSP00000428706 ENSP00000428466 ENSP00000428949 ENSP00000430355 ENSP00000430562 ENSP00000321703 ENSP00000276520 ENSP00000430819 ENSP00000430959 ENSP00000428175 ENSP00000429330 ENSP00000428253 ENSP00000430306 ENSP00000429418 ENSP00000393647 ENSP00000332794 ENSP00000327818 ENSP00000369263
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
TACC1 for ontologies About GeneDecksing
TACC1 Antibody Products:
Assay Products for TACC1: |
Protein
Domains /
Families
for TACC1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TACC1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75410ProtoNet protein and cluster: O75410 1 Blocks protein family: IPB007707 Transforming acidic coiled-coil-containing
UniProtKB/Swiss-Prot: TACC1_HUMAN, O75410Similarity: Belongs to the TACC familySimilarity: Contains 2 SPAZ (Ser/Pro-rich AZU-1) domains |
Function
for TACC1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TACC1_HUMAN, O75410Function: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues Genatlas biochemistry entry for TACC1:transforming acidic coiled-coil gene 1,highly expressed during early embryogenesis,potentially promoting tumorigenicityin breast cancers with amplification of the 8p11 region
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): TACC1 (NM_006283) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TACC1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TACC1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TACC1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
TACC1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TACC1:
|
Pathways & Interactions
for TACC1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Aurora A signaling | | | 2 | Aurora B signaling | |
2  BioSystems Pathways for TACC1
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TACC1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/13 Interacting proteins for TACC1 (O754101, 3 ENSP000003217034) via UniProtKB, MINT, STRING, and/or I2D (see all 13)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| AURKB | Q96GD41, 3, ENSP000003139504 | EBI-624278,EBI-624291 I2D:
score=4 STRING: ENSP00000313950 | | SNRPG | P623081, 3, ENSP000002723484 | EBI-624252,EBI-1056206 I2D:
score=4 STRING: ENSP00000272348 | | TDRD7 | Q8NHU61, 3, ENSP000003474444 | EBI-624237,EBI-624505 I2D:
score=4 STRING: ENSP00000347444 | | CKAP5 | Q140081, 3, ENSP000003465664 | EBI-624237,EBI-310585 I2D:
score=3 STRING: ENSP00000346566 | | LSM7 | Q9UK451, 3, ENSP000002526224 | EBI-624252,EBI-348372 I2D:
score=4 STRING: ENSP00000252622 |
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
TACC1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TACC1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TACC1
Search CenterWatch for drugs/clinical trials and news about TACC1
|
Transcripts
for TACC1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TACC1 gene (3 alternative transcripts): NM_001122824.1 NM_001146216.2 NM_006283.2 Unigene Cluster for TACC1: Transforming, acidic coiled-coil containing protein 1 Hs.279245 [show with all ESTs]Unigene Representative Sequence: CR93361818/33 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 33): ENST00000519416(uc011lby.1) ENST00000520615 ENST00000522474 ENST00000520340
ENST00000522983 ENST00000518415 ENST00000521642(uc003xme.1 uc003xmd.1)
ENST00000521050 ENST00000522904 ENST00000522752(uc010lwo.1) ENST00000524354
ENST00000522544 ENST00000523239 ENST00000317827(uc003xmb.4 uc003xlz.3 uc003xmc.4 uc011lbz.2 uc010lwp.3 uc003xmf.4 uc011lcb.2 uc011lcd.2)
ENST00000276520 ENST00000521528 ENST00000520973 ENST00000521935
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): TACC1 (NM_006283) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TACC1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TACC1 |
Additional cDNA sequence: AB029026.1 AF049910.1 AF075051.1 AK057659.1 AK098223.1 AK124297.1 AK129750.1 AK294931.1 AK295071.1 AK295841.1 AK303596.1 AK304507.1 AK304725.1 AK304774.1 AK308849.1 AK314620.1 AY039239.1 AY072873.2 AY072874.1 AY072875.1 AY072876.2 AY139007.1 AY177411.1 BC041391.1 BX647696.1 CR933618.1 24/25 DOTS entries (see all 25): DT.445878 DT.75170359 DT.95240638 DT.100797363 DT.100031422 DT.92006861 DT.40125901 DT.120636115 DT.100031423 DT.100010104 DT.100737639 DT.100797378 DT.120636076 DT.120636091 DT.120636160 DT.40233461 DT.95222429 DT.100797361 DT.425248 DT.100736149 DT.91680115 DT.91955944 DT.95075498 DT.95120300 24/520 AceView cDNA sequences (see all 520): BQ271606 AA252596 BG569810 BQ933648 AW505353 BQ431104 AI373406 CB121116 BE677181 AA341700 AY139007 AA397746 AL045829 CD676485 AI804791 AA487071 AA180487 BQ893716 AA548642 CA390222 BQ084397 BU145614 AW072909 BM673819
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for TACC1 (see all 16) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | · | 9f | · | 9g | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | |
| ExUns: | 16c | ^ | 17 | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ | 20 |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | |
| SP5: | | | | | | | - | | - | | | | | |
ECgene alternative splicing isoforms for TACC1
|
Expression
for TACC1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TACC1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCATTGCC
About this image
See TACC1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TACC1
SOURCE GeneReport for Unigene cluster: Hs.279245
UniProtKB/Swiss-Prot: TACC1_HUMAN, O75410Tissue specificity: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain,weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues,but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer
SABiosciences Custom PCR Arrays for TACC1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TACC1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TACC1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TACC1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TACC1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TACC1 |
Orthologs
for TACC1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TACC1 gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TACC11 |
transforming, acidic coiled-coil containing protein more |
65.49(n)
63.57(a) |
|
431253 XM_428807.3 XP_428807.3 |
lizard
(Anolis carolinensis) |
Reptilia |
TACC16 |
-- |
48(a) |
1 ↔ 1 |
GL343418.1(426214-444885) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.58362 |
Transcribed sequence with weak similarity to protein more |
74.64(n) |
|
137722889 |
zebrafish
(Danio rerio) |
Actinopterygii |
tacc11 |
transforming, acidic coiled-coil containing protein more |
57.18(n)
52.68(a) |
|
565711 XM_688981.5 XP_694073.4 |
fruit fly
(Drosophila melanogaster) |
Insecta |
tacc6 |
transforming acidic coiled-coil protein |
10(a) |
possible ortholog |
3R(559376-574778) |
ENSEMBL Gene Tree for TACC1 (if available)
TreeFam Gene Tree for TACC1 (if available) |
Paralogs
for TACC1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TACC1 gene
- TACC32 TACC22
2 SIMAP similar genes for TACC1 using alignment to 13 protein entries: TACC1_HUMAN (see all proteins):DKFZp686K18126 TACC2
TACC1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for TACC1
PGOHUM00000238728 PGOHUM00000256607
|
Genomic Variants
for TACC1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TACC1 (38585704 - 38710546 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TACC1
1 CNV: 65113 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TACC1 |
|
Disorders
/ Diseases
for TACC1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TACC1 for disorders About GeneDecksing
OMIM gene information: 605301
OMIM disorders: --
11  diseases for TACC1: About MalaCardsbreast cancer gastric cancer myeloproliferative disorder multiple myeloma
prostate cancer, progression of ovarian cancer prostate cancer myeloma
prostatitis cerebritis adenocarcinoma
5 Novoseek disease relationships for TACC1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: TACC1 (2 documents)
Export disorders for TACC1 gene to outside databases
|
Publications
for TACC1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TACC1 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with TACC1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators. (PubMed id 12165861)1, 2, 9 Conte N.... Birnbaum D. (2002)
- Altered splicing pattern of TACC1 mRNA in gastric cancer. (PubMed id 12547166)1, 2, 9 Line A.... Rees R.C. (2002)
- Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon. (PubMed id 10435627)1, 2, 9 Still I.H.... Cowell J.K. (1999)
- Aurora B -TACC1 protein complex in cytokinesis. (PubMed id 15064709)1, 2, 9 Delaval B.... Birnbaum D. (2004)
- TACC1-chTOG-Aurora A protein complex in breast cancer. (PubMed id 14603251)1, 2, 9 Conte N.... Birnbaum D. (2003)
- Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells. (PubMed id 11903063)1, 2, 9 Lauffart B.... Still I.H. (2002)
- The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. (PubMed id 11121038)1, 2, 9 Gergely F....Raff J.W. (2000)
- Aurora-C interacts with and phosphorylates the transforming acidic coiled-coil 1 protein. (PubMed id 21531210)1, 2 Gabillard J.C.... Arlot-Bonnemains Y. (2011)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
|
External Searches for TACC1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TACC1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TACC1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TACC1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TACC1 gene:
Search GeneIP for patents involving TACC1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for TACC1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TACC1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TACC1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TACC1 | | | OriGene Protein Over-expression Lysate for TACC1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TACC1 | | OriGene 3'-UTR Clone for TACC1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TACC1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TACC1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TACC1 | | OriGene Custom Protein Services for TACC1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TACC1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TACC1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TACC1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TACC1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TACC1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TACC1 |
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| | | | Search Tocris compounds for TACC1 |
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 | | | TACC1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TACC1 |
|  |  |  | | | | Search ThermoFisher Antibodies for TACC1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TACC1 |
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