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TAC3 Gene

protein-coding GIFtS: 60

GC12M055690

tachykinin 3
(Previous names: neuromedin K, neurokinin beta )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: NKNB)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
NKB ^¹, ²
NKNB ^², ³, ⁵
PRO1155 ^²
ZNEUROK1 ^¹, ², ³

Descriptions
gamma tachykinin 3 ^²
neurokinin B-like protein ^²
neurokinin beta ^¹, ²
neurokinin-B protein ^²
neuromedin K ^¹
neuromedin K, neurokinin beta ^²
preprotachykinin B ^²
tachykinin 3 ^²

External Ids
HGNC: 11521¹
Entrez Gene: 6866²
UniProtKB: Q9UHF0³
Ensembl: ENSG00000166863⁷

Search outside databases for aliases for TAC3 gene

Previous GC identifers: GC12M057378 GC12M057628 GC12M057120

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TKNK_HUMAN, Q9UHF0

Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are

potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles

(By similarity)

Gene Wiki entry for TAC3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TAC3 gene

Entrez Gene cytogenetic band: 12q13-q21 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13-q21

TAC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M055690: (about GC identifiers)

Start:	55,690,051 bp from pter
End:	55,696,592 bp from pter
Size:	6,542 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_029419.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: TKNK_HUMAN, Q9UHF0 (See protein sequence)

Recommended Name: Tachykinin-3 precursor

Size: 121 amino acids; 13438 Da

Subcellular location: Secreted

Developmental stage: In pregnancy, the expression of NKB is confined to the outer

syncytiotrophoblast of the placenta, significant concentrations of NKB can be detected in plasma

as early as week 9, and plasma concentrations of NKB are grossly elevated in pregnancy-induced

hypertension and pre-eclampsia

PDB structures from and Proteopedia :

1P9F (3D)

Secondary accessions: Q6IAG2 Q71BC6 Q71BC9

Alternative splicing: 3 isoforms: Q9UHF0-1 Q9UHF0-2 Q9UHF0-3

REFSEQ proteins (2 alternative transcripts):

NP_001006668.1 NP_037383.1

ENSEMBL proteins:

ENSP00000350236 ENSP00000377445 ENSP00000300108 ENSP00000368721

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Neurokinin B )
	Human Recombinant Proteins from Abnova (TAC3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	TAS	10866201
GO:0005625	soluble fraction	TAS	10866201

About this table

Antibodies for TAC3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for TAC3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Neurokinin B ), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TAC3)
	Novus Biologicals Antibodies for TAC3

Assays for TAC3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UHF0

ProtoNet protein and cluster: Q9UHF0

1 Blocks protein family: IPB002040 Tachykinin/Neurokinin

UniProtKB/Swiss-Prot: TKNK_HUMAN, Q9UHF0

Similarity: Belongs to the tachykinin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAC3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAC3)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001006667

Applied Biosystems Silencer® siRNAs for TAC3

Sigma-Aldrich siRNA for TAC3

Sigma-Aldrich shRNA for TAC3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TAC3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001006667
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001006667
untagged cDNA clones in CMV expression vector (see all 2): NM_001006667

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001006667

UniProtKB/Swiss-Prot: TKNK_HUMAN, Q9UHF0

Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are

potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles

tachykinin 3,neurokinin B (neuromedin K)

1 MGI phenotypic allele

for Tac2 (no phenotypes)

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005102	receptor binding	TAS	10866201

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/15 Interacting proteins for TAC3 (Q9UHF0² ENSP00000350236³) via UniProtKB, MINT, and/or STRING (see all 15 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FEZ1	Q99689²	MINT-65739
GPRASP1	Q5JY77²	MINT-65737
PTN	P21246²	MINT-65735
UBR1	Q8IWV7²	MINT-65738
TACR3	ENSP00000303325³	STRING (score=.999)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007217	tachykinin receptor signaling pathway	TAS	10866201
GO:0007218	neuropeptide signaling pathway	IEA	--
GO:0007565	female pregnancy	TAS	10866201

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for TAC3 available from Tocris Bioscience

Compound	Action	CAS number
Neurokinin B (human, porcine)	Endogenous tachykinin peptide	[86933-75-7]
SB 222200	Potent, selective non-peptide NK3 antagonist. Brain penetrant	[174635-69-9]
SB 218795	Potent, selective non-peptide NK3 antagonist	[174635-53-1]
Senktide	Tachykinin NK3 agonist	[106128-89-6]

About this table

10/12 Novoseek chemical compound relationships for TAC3 gene (see all 12 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
senktide	93.27	19	10953048 (2), 8818331 (2), 7830490 (1), 9667146 (1) (see all 13)
eledoisin	86.80	9	1708071 (3), 1712834 (1), 16127708 (1), 1694464 (1) (see all 5)
septide	85.77	5	7824047 (1), 8882625 (1), 10753681 (1)
physalaemin	76.53	6	1708071 (3), 1694464 (1), 7824047 (1)
kassinin	74.68	3	8859022 (1), 7684358 (1)
bestatin	54.08	2	12788812 (1), 11071311 (1)
fmlp	18.55	2	7684358 (2)
superoxide	13.87	4	1704475 (1), 1697194 (1), 7684358 (1), 10189055 (1)
estradiol	0.00	1	7529897 (1)
nitric oxide	0.00	2	8751080 (1), 8882625 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAC3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAC3)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001006667

Sigma-Aldrich siRNA for TAC3

Sigma-Aldrich shRNA for TAC3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_013251

REFSEQ mRNAs for TAC3 gene (2 alternative transcripts):

NM_001006667.1 NM_013251.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_013251

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001006667
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001006667
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001006667

Additional cDNA sequence:

AF186112.1 AF216586.1 AF537115.1 AF537118.1 AY358679.1 BC032145.2 CR457193.1 CR620932.1

4 DOTS entries:

DT.410221 DT.101983456 DT.101983455 DT.101974196

24/81 AceView cDNA sequences (see all 81 ):

BC032145 BX118017 AF186112 BC059387 NM_005379 AF537116 CD620409 AI832211

AF537114 AF105424 AF537119 AF127026 AF537121 BX114126 AI139283 AF537118

BG002828 AF537117 CD620413 AF537120 CR620932 AF537113 AY358679 AF537115

highest scoring ESTs for TAC3:

AA004764 AF186112 AF216586 AF537113 AF537114 AF537115 AF537116 AF537117 AF537118 AF537119

Unigene Cluster for TAC3:

Tachykinin 3

Hs.9730 [show with all ESTs]

Unigene Representative Sequence: AY358679

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TAC3 (see all 10 )

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b
SP1:													-
SP2:													-										-
SP3:													-				-
SP4:													-								-		-
SP5:													-				-						-

About this scheme

ECgene alternative splicing isoforms for TAC3

4 Ensembl transcripts including schematic representations:

ENST00000357616 ENST00000393867 ENST00000300108 ENST00000379411

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TAC3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TAC3

¹ / ² / ³

3 probe-sets matching TAC3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
55518_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	AA004764	0.80	1.00	0.91	1
219992_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_013251	0.60	1.00	0.82	1
219992_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks TAC3 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACTTCTTTGT

SOURCE GeneReport for Unigene cluster: Hs.9730

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TAC3 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TAC3¹	--	tachykinin 3	81.27(n) 74.38(a)	607315 XM_843938.1 XP_849031.1
chimpanzee (Pan troglodytes)	TAC3¹	--	tachykinin 3	99.72(n) 99.17(a)	746748 XM_001168338.1 XP_001168338.1
cow (Bos taurus)	TAC3¹	--	tachykinin 3	79.61(n) 68.6(a)	281513 NM_181017.1 NP_851360.1
rat (Rattus norvegicus)	Tac2¹	--	tachykinin 2	75.38(n) 66.67(a)	29191 NM_019162.1 NP_062035.1
mouse (Mus musculus)	Tac2^{1, 5}	10⁵	tachykinin 2^{1, 5}	77.18(n)¹ 70.27(a)¹	21334¹ NM_009312.1¹ NP_033338.1¹ AF186116⁵ BC031348⁵ (see all 8)

About this table Species with no ortholog for TAC3

ENSEMBL Gene Tree for TAC3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/29 NCBI SNPs in TAC3 are shown (see all 29 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2291855^1,2	F,H	55696458(-)	`GCCCCC/TGGCAC`	1	--	ut5¹ ese³		4		EA WA	1772
	rs12579947^1,2	H	55698257(+)	`ataatC/Ttaatt`	1	--	ng3¹		4		EU EA WA	400
	rs11614223^1,2	H	55696656(+)	`GAGTCA/CCCAAT`	1	--	ng3¹		4		EU EA WA	416
	rs733629^1,2	C,F,H,O	55692711(+)	`AGACTT/CTCCTG`	1	--	int¹		8		NA MN EU EA WA	2080
	rs17119330^1,2	C,F,H	55695506(+)	`TTGTAG/AGGCAC`	1	--	int¹		15		NA EU EA WA	1364
	rs2122694^1,2	C,F,H	55694600(-)	`TGAGAG/AGGATT`	1	--	int¹		4		EU EA WA	400
	rs17119327^1,2	C,F,H	55695007(+)	`CCGATG/ATAATT`	1	--	int¹		16		NA EU EA WA	1466
	rs2270734^1,2	F,H	55692591(-)	`ACTGCC/TCGTCA`	1	--	int¹		5		EA EU WA	1914
	rs11609825^1,2	A,C	55690465(+)	`GAGAGG/CAAAGA`	1	--	int¹ trp³		3		NA	130
--	rs61415706^1,2	--	55697840(+)	`GTAATC/TTCAGC`	1	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for TAC3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 162330 disorders: 146110

4 Novoseek disease relationships for TAC3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
preeclampsia	54.67	27	16709596 (4), 17318561 (2), 17480147 (2), 10866201 (2) (see all 11)
hypertrophy	28.46	4	14764001 (1), 10095095 (1), 19094085 (1), 18614256 (1)
inflammation	1.20	2	11049735 (1), 7684358 (1)
edema	0.00	1	11049735 (1)

About this table

Human Gene Mutation Database: TAC3
Human Genome Epidemiology Navigator: TAC3 (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/130 PubMed articles for TAC3 gene (see all 130 ):

Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. (PubMed id 10866201)^{1, 2, 3, 4} Page N.M....Lowry P.J. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{3, 4} Clark H.F....Gray A. (2003)
A cDNA encoding the precursor of the rat neuropeptide, neurokinin B. (PubMed id 3479225)^{2, 3} Bonner T.I....Young W.S. (1987)
Neurokinin B causes concentration-dependent relaxation of isolated human placental resistance vessels. (PubMed id 14700748)^{1, 3} Laliberte C....Kaufman S. (2004)
Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia. (PubMed id 16709596)^{1, 3} Page N.M....Morrish D.W. (2006)
Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women. (PubMed id 1708331)^{1, 3} Rance N.E. and Young W.S. (1991)
Third trimester plasma neurokinin B levels in women with and without preeclampsia. (PubMed id 18240076)^{1, 3} Geissbuehler V....Moser R. (2008)
Neurokinin B is a paracrine vasodilator in the human fetal placental circulation. (PubMed id 12727971)^{1, 3} Brownbill P....Sibley C.P. (2003)
Placental neurokinin B mRNA expression increases at preterm labor. (PubMed id 17561251)^{1, 3} Torricelli M....Petraglia F. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6866	HGNC: 11521	AceView: MYO1AandTAC3	Ensembl:ENSG00000166863	euGenes: HUgn6866
ECgene: TAC3	H-InvDB: TAC3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for TAC3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for TAC3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TAC3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TAC3		Antibodies for TAC3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TAC3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (TAC3)
	Antibodies (TAC3)
	Chimera RNAi (TAC3)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Neurokinin B )
	Antibodies (Neurokinin B )

Search OriGene for TAC3

Tocris compounds for TAC3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for TAC3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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TAC3 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for TAC3

Summaries
for TAC3

Genomic Location
for TAC3

Proteins
for TAC3

Protein Domains/
Families
for TAC3

Gene Function
for TAC3

Pathways & Interactions
for TAC3

Drugs & Compounds
for TAC3

Transcripts
for TAC3

Expression
for TAC3

Orthologs
for TAC3

Paralogs
for TAC3

SNPs/Variants
for TAC3

Disorders & Mutations
for TAC3

Medical News
for TAC3

Publications
for TAC3

Search for TAC3

Genome Databases showing TAC3

Other Databases showing TAC3

Specialized Databases showing TAC3

Licensable Technologies
for TAC3

Services
for TAC3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TAC3 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor TAC3

Summariesfor TAC3

Genomic Locationfor TAC3

Proteinsfor TAC3

Protein Domains/Familiesfor TAC3

Gene Functionfor TAC3

Pathways & Interactionsfor TAC3

Drugs & Compoundsfor TAC3

Transcriptsfor TAC3

Expression for TAC3

Orthologsfor TAC3

Paralogsfor TAC3

SNPs/Variantsfor TAC3

Disorders & Mutationsfor TAC3

Medical Newsfor TAC3

Publicationsfor TAC3

Search for TAC3

Genome Databases showing TAC3

Other Databases showing TAC3

Specialized Databases showing TAC3

Licensable Technologiesfor TAC3

Servicesfor TAC3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TAC3

Summaries
for TAC3

Genomic Location
for TAC3

Proteins
for TAC3

Protein Domains/
Families
for TAC3

Gene Function
for TAC3

Pathways & Interactions
for TAC3

Drugs & Compounds
for TAC3

Transcripts
for TAC3

Expression
for TAC3

Orthologs
for TAC3

Paralogs
for TAC3

SNPs/Variants
for TAC3

Disorders & Mutations
for TAC3

Medical News
for TAC3

Publications
for TAC3

Licensable Technologies
for TAC3

Services
for TAC3