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Aliases for TAAR9 Gene

Aliases for TAAR9 Gene

  • Trace Amine Associated Receptor 9 (Gene/Pseudogene) 2 3 5
  • Trace Amine Receptor 3 2 3 4
  • Trace Amine Receptor 9 3 4
  • TRAR3 3 4
  • TAR3 3 4
  • TA3 3 4
  • Trace Amine Associated Receptor 9 2
  • Trace Amine-Associated Receptor 9 3
  • TaR-3 4
  • TaR-9 4
  • TAR9 3

External Ids for TAAR9 Gene

Previous HGNC Symbols for TAAR9 Gene

  • TRAR3

Previous GeneCards Identifiers for TAAR9 Gene

  • GC06P132903
  • GC06P130434

Summaries for TAAR9 Gene

Entrez Gene Summary for TAAR9 Gene

  • TAAR9 is a member of a large family of rhodopsin G protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Jul 2005]

GeneCards Summary for TAAR9 Gene

TAAR9 (Trace Amine Associated Receptor 9 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Monoamine GPCRs. GO annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity. An important paralog of this gene is TAAR6.

UniProtKB/Swiss-Prot for TAAR9 Gene

  • Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.

Gene Wiki entry for TAAR9 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAAR9 Gene

Genomics for TAAR9 Gene

Regulatory Elements for TAAR9 Gene

Enhancers for TAAR9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G132065 1 FANTOM5 ENCODE dbSUPER 2.6 -472.6 -472561 0.8 FOXA2 JUN FOS TAAR8 TAAR9 GC06P132061 ENSG00000236166
GH06G132530 0.7 Ensembl 0.4 -7.9 -7888 0.4 CTCF PKNOX1 ZNF654 ZNF362 RNF2 TRIM22 ZNF384 REST RAD21 SMC3 SLC18B1 VNN2 TAAR9 RPL21P66
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TAAR9 on UCSC Golden Path with GeneCards custom track

Genomic Location for TAAR9 Gene

Chromosome:
6
Start:
132,538,288 bp from pter
End:
132,539,336 bp from pter
Size:
1,049 bases
Orientation:
Plus strand

Genomic View for TAAR9 Gene

Genes around TAAR9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TAAR9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TAAR9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TAAR9 Gene

Proteins for TAAR9 Gene

  • Protein details for TAAR9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96RI9-TAAR9_HUMAN
    Recommended name:
    Trace amine-associated receptor 9
    Protein Accession:
    Q96RI9

    Protein attributes for TAAR9 Gene

    Size:
    348 amino acids
    Molecular mass:
    39016 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TAAR9 Gene

Post-translational modifications for TAAR9 Gene

  • Glycosylation at isoforms=4 and isoforms=19
  • Modification sites at PhosphoSitePlus

Other Protein References for TAAR9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TAAR9 Gene

Domains & Families for TAAR9 Gene

Gene Families for TAAR9 Gene

Protein Domains for TAAR9 Gene

Suggested Antigen Peptide Sequences for TAAR9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96RI9

UniProtKB/Swiss-Prot:

TAAR9_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with TAAR9: view

Function for TAAR9 Gene

Molecular function for TAAR9 Gene

UniProtKB/Swiss-Prot Function:
Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.

Gene Ontology (GO) - Molecular Function for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001594 trace-amine receptor activity IBA --
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity TAS 15718104
genes like me logo Genes that share ontologies with TAAR9: view
genes like me logo Genes that share phenotypes with TAAR9: view

Animal Models for TAAR9 Gene

MGI Knock Outs for TAAR9:

Animal Model Products

  • Taconic Biosciences Mouse Models for TAAR9

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for TAAR9

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TAAR9 Gene

Localization for TAAR9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAAR9 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA,IC --
genes like me logo Genes that share ontologies with TAAR9: view

No data available for Subcellular locations from COMPARTMENTS for TAAR9 Gene

Pathways & Interactions for TAAR9 Gene

genes like me logo Genes that share pathways with TAAR9: view

Interacting Proteins for TAAR9 Gene

Selected Interacting proteins: Q96RI9-TAAR9_HUMAN for TAAR9 Gene via IID

Gene Ontology (GO) - Biological Process for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS,IEA --
genes like me logo Genes that share ontologies with TAAR9: view

No data available for SIGNOR curated interactions for TAAR9 Gene

Drugs & Compounds for TAAR9 Gene

No Compound Related Data Available

Transcripts for TAAR9 Gene

mRNA/cDNA for TAAR9 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TAAR9 Gene

Trace amine associated receptor 9 (gene/pseudogene):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for TAAR9

Alternative Splicing Database (ASD) splice patterns (SP) for TAAR9 Gene

No ASD Table

Relevant External Links for TAAR9 Gene

GeneLoc Exon Structure for
TAAR9
ECgene alternative splicing isoforms for
TAAR9

Expression for TAAR9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TAAR9 Gene

NURSA nuclear receptor signaling pathways regulating expression of TAAR9 Gene:

TAAR9

SOURCE GeneReport for Unigene cluster for TAAR9 Gene:

Hs.434116
genes like me logo Genes that share expression patterns with TAAR9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TAAR9 Gene

Orthologs for TAAR9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TAAR9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TAAR9 34 35
  • 87.55 (n)
mouse
(Mus musculus)
Mammalia Taar9 34 16 35
  • 83.91 (n)
rat
(Rattus norvegicus)
Mammalia Taar9 34
  • 83.63 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 74 (a)
OneToMany
-- 35
  • 74 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 39 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii taar13e 35
  • 41 (a)
ManyToMany
Species where no ortholog for TAAR9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TAAR9 Gene

ENSEMBL:
Gene Tree for TAAR9 (if available)
TreeFam:
Gene Tree for TAAR9 (if available)

Paralogs for TAAR9 Gene

Paralogs for TAAR9 Gene

(11) SIMAP similar genes for TAAR9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TAAR9: view

Variants for TAAR9 Gene

Sequence variations from dbSNP and Humsavar for TAAR9 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000175830 -- 132,539,569(+) TTCTG(G/T)TTCCT downstream-variant-500B
rs1000909537 -- 132,538,134(+) TTATA(G/T)TTAAT upstream-variant-2KB
rs1001508997 -- 132,537,775(+) TTGAA(A/G)GAGAT upstream-variant-2KB
rs1001834822 -- 132,537,076(+) ATATA(C/T)TTGAC upstream-variant-2KB
rs1002111942 -- 132,536,431(+) TAAAG(G/T)CTGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TAAR9 Gene

Variant ID Type Subtype PubMed ID
esv3890949 CNV loss 25118596

Relevant External Links for TAAR9 Gene

Human Gene Mutation Database (HGMD)
TAAR9
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TAAR9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TAAR9 Gene

Disorders for TAAR9 Gene

Relevant External Links for TAAR9

Genetic Association Database (GAD)
TAAR9
Human Genome Epidemiology (HuGE) Navigator
TAAR9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TAAR9

No disorders were found for TAAR9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TAAR9 Gene

Publications for TAAR9 Gene

  1. Correlation of a set of gene variants, life events and personality features on adult ADHD severity. (PMID: 20006992) MA1ller D.J. … Kennedy J.L. (J Psychiatr Res 2010) 3 46 64
  2. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. (PMID: 15718104) Lindemann L. … Hoener M.C. (Genomics 2005) 2 3 64
  3. Trace amines: identification of a family of mammalian G protein- coupled receptors. (PMID: 11459929) Borowsky B. … Gerald C. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4 64
  4. International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature. (PMID: 19325074) Maguire J.J. … Davenport A.P. (Pharmacol. Rev. 2009) 22 64
  5. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PMID: 18240029) Luttrell L.M. (Mol. Biotechnol. 2008) 3 64

Products for TAAR9 Gene

  • Addgene plasmids for TAAR9

Sources for TAAR9 Gene

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