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Aliases for TAAR9 Gene

Aliases for TAAR9 Gene

  • Trace Amine Associated Receptor 9 (Gene/Pseudogene) 2 3
  • Trace Amine Receptor 3 2 3 4
  • TAR3 3 4 6
  • TA3 3 4 6
  • Trace Amine Receptor 9 3 4
  • TRAR3 3 4
  • Trace Amine Associated Receptor 9 2
  • Trace Amine-Associated Receptor 9 3
  • TaR-3 4
  • TaR-9 4
  • TAR9 3

External Ids for TAAR9 Gene

Previous HGNC Symbols for TAAR9 Gene

  • TRAR3

Previous GeneCards Identifiers for TAAR9 Gene

  • GC06P132903
  • GC06P130434

Summaries for TAAR9 Gene

Entrez Gene Summary for TAAR9 Gene

  • TAAR9 is a member of a large family of rhodopsin G protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Jul 2005]

GeneCards Summary for TAAR9 Gene

TAAR9 (Trace Amine Associated Receptor 9 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity. An important paralog of this gene is HTR6.

UniProtKB/Swiss-Prot for TAAR9 Gene

  • Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood

Gene Wiki entry for TAAR9 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAAR9 Gene

Genomics for TAAR9 Gene

Regulatory Elements for TAAR9 Gene

Genomic Location for TAAR9 Gene

Start:
132,538,288 bp from pter
End:
132,539,336 bp from pter
Size:
1,049 bases
Orientation:
Plus strand

Genomic View for TAAR9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TAAR9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TAAR9 Gene

Proteins for TAAR9 Gene

  • Protein details for TAAR9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96RI9-TAAR9_HUMAN
    Recommended name:
    Trace amine-associated receptor 9
    Protein Accession:
    Q96RI9
    Secondary Accessions:

    Protein attributes for TAAR9 Gene

    Size:
    348 amino acids
    Molecular mass:
    39016 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TAAR9 Gene

Proteomics data for TAAR9 Gene at MOPED

Post-translational modifications for TAAR9 Gene

  • Glycosylation at Asn4 and Asn19
  • Modification sites at PhosphoSitePlus

Other Protein References for TAAR9 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for TAAR9 Gene

Domains for TAAR9 Gene

Gene Families for TAAR9 Gene

HGNC:
  • TAAR :GPCR / Class A : Trace amine associated receptors
IUPHAR :

Protein Domains for TAAR9 Gene

Suggested Antigen Peptide Sequences for TAAR9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96RI9

UniProtKB/Swiss-Prot:

TAAR9_HUMAN :
  • Q96RI9
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with TAAR9: view

Function for TAAR9 Gene

Molecular function for TAAR9 Gene

UniProtKB/Swiss-Prot Function: Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood

Gene Ontology (GO) - Molecular Function for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001594 trace-amine receptor activity IEA --
GO:0004930 G-protein coupled receptor activity TAS 15718104
genes like me logo Genes that share ontologies with TAAR9: view

Phenotypes for TAAR9 Gene

genes like me logo Genes that share phenotypes with TAAR9: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TAAR9 Gene

Localization for TAAR9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAAR9 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TAAR9: view

No data available for Subcellular locations from COMPARTMENTS for TAAR9 Gene

Pathways for TAAR9 Gene

genes like me logo Genes that share pathways with TAAR9: view

Pathways by source for TAAR9 Gene

Interacting Proteins for TAAR9 Gene

Gene Ontology (GO) - Biological Process for TAAR9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with TAAR9: view

Transcripts for TAAR9 Gene

mRNA/cDNA for TAAR9 Gene

(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TAAR9 Gene

Trace amine associated receptor 9 (gene/pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TAAR9 Gene

No ASD Table

Relevant External Links for TAAR9 Gene

GeneLoc Exon Structure for
TAAR9
ECgene alternative splicing isoforms for
TAAR9

Expression for TAAR9 Gene

mRNA expression in normal human tissues for TAAR9 Gene

SOURCE GeneReport for Unigene cluster for TAAR9 Gene Hs.434116

genes like me logo Genes that share expressions with TAAR9: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TAAR9 Gene

Orthologs for TAAR9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TAAR9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TAAR9 35
  • 87.55 (n)
  • 90.8 (a)
TAAR9 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Taar9 35
  • 83.91 (n)
  • 87.79 (a)
Taar9 16
Taar9 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 74 (a)
OneToMany
-- 36
  • 72 (a)
OneToMany
-- 36
  • 74 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 39 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Taar9 35
  • 83.63 (n)
  • 87.72 (a)
zebrafish
(Danio rerio)
Actinopterygii taar13e 36
  • 41 (a)
ManyToMany
Species with no ortholog for TAAR9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TAAR9 Gene

ENSEMBL:
Gene Tree for TAAR9 (if available)
TreeFam:
Gene Tree for TAAR9 (if available)

Paralogs for TAAR9 Gene

Paralogs for TAAR9 Gene

Selected SIMAP similar genes for TAAR9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TAAR9: view

Variants for TAAR9 Gene

Sequence variations from dbSNP and Humsavar for TAAR9 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs2842897 -- 132,539,574(-) AAGTA(A/G)GGAAC downstream-variant-500B
rs2842898 -- 132,539,383(-) TTGCA(C/G)TTGAC downstream-variant-500B
rs2842899 -- 132,538,470(-) TTGTT(A/T)GAAGT reference, stop-gained
rs5880132 -- 132,536,656(+) CCTTA(-/ATC/TCA)GGAGA upstream-variant-2KB
rs6913154 -- 132,536,865(+) ATTGA(C/T)TTAAA upstream-variant-2KB

Relevant External Links for TAAR9 Gene

HapMap Linkage Disequilibrium report
TAAR9
Human Gene Mutation Database (HGMD)
TAAR9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TAAR9 Gene

Disorders for TAAR9 Gene

Relevant External Links for TAAR9

Genetic Association Database (GAD)
TAAR9
Human Genome Epidemiology (HuGE) Navigator
TAAR9
genes like me logo Genes that share disorders with TAAR9: view

No data available for UniProtKB/Swiss-Prot for TAAR9 Gene

Publications for TAAR9 Gene

  1. Trace amines: identification of a family of mammalian G protein- coupled receptors. (PMID: 11459929) Borowsky B. … Gerald C. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4
  2. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. (PMID: 15718104) Lindemann L. … Hoener M.C. (Genomics 2005) 2 3
  3. Correlation of a set of gene variants, life events and personality features on adult ADHD severity. (PMID: 20006992) MA1ller D.J. … Kennedy J.L. (J Psychiatr Res 2010) 3 48
  4. International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature. (PMID: 19325074) Maguire J.J. … Davenport A.P. (Pharmacol. Rev. 2009) 23
  5. A second class of chemosensory receptors in the olfactory epithelium. (PMID: 16878137) Liberles S.D. … Buck L.B. (Nature 2006) 3

Products for TAAR9 Gene

  • Pathway & Disease-focused RT² Profiler PCR Arrays
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TAAR9
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TAAR9
    • Block miRNA regulation of TAAR9 using miScript Target Protectors

    Sources for TAAR9 Gene

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