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Aliases for TAAR3 Gene

Aliases for TAAR3 Gene

  • Trace Amine Associated Receptor 3 (Gene/Pseudogene) 2 3 5
  • G Protein-Coupled Receptor 57 2 3
  • GPR57 3 4
  • Trace Amine Associated Receptor 2 Pseudogene 3
  • Trace Amine Associated Receptor 3 2
  • G-Protein Coupled Receptor 57 4
  • Trace Amine Receptor 3 4
  • HTaar3 4
  • GPR58 3
  • TAAR2 3
  • TaR-3 4

External Ids for TAAR3 Gene

Previous HGNC Symbols for TAAR3 Gene

  • GPR57

Previous GeneCards Identifiers for TAAR3 Gene

  • GC06M132972
  • GC06M130504
  • GC06M132930

Summaries for TAAR3 Gene

GeneCards Summary for TAAR3 Gene

TAAR3 (Trace Amine Associated Receptor 3 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity.

UniProtKB/Swiss-Prot for TAAR3 Gene

  • Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the corresponding alcohols, isoamylalcohol and cyclohexanol. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity).

Gene Wiki entry for TAAR3 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAAR3 Gene

Genomics for TAAR3 Gene

Regulatory Elements for TAAR3 Gene

Enhancers for TAAR3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F132611 0.2 ENCODE 0.8 -3.3 -3283 1.9 GATAD2A NR2F1 FOXA3 CEBPB ZNF384 ZBTB40 NR2F2 RARA HNF1A SMARCA4 TAAR5 VNN2 ENPP3 TAAR3 TAAR2
GH06F132607 0.4 ENCODE 0.8 +1.5 1462 1.7 YY1 SNORA33 TAAR3 TAAR4P
GH06F132614 0.5 Ensembl 0.4 -5.5 -5499 0.4 MLLT1 EBF1 TAAR5 VNN1 TAAR2 TAAR3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TAAR3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TAAR3 Gene

Chromosome:
6
Start:
132,608,225 bp from pter
End:
132,609,302 bp from pter
Size:
1,078 bases
Orientation:
Minus strand

Genomic View for TAAR3 Gene

Genes around TAAR3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TAAR3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TAAR3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TAAR3 Gene

Proteins for TAAR3 Gene

  • Protein details for TAAR3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P1P4-TAAR3_HUMAN
    Recommended name:
    Putative trace amine-associated receptor 3
    Protein Accession:
    Q9P1P4

    Protein attributes for TAAR3 Gene

    Size:
    343 amino acids
    Molecular mass:
    39065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TAAR3 Gene

Post-translational modifications for TAAR3 Gene

No data available for DME Specific Peptides for TAAR3 Gene

Domains & Families for TAAR3 Gene

Gene Families for TAAR3 Gene

Protein Domains for TAAR3 Gene

Suggested Antigen Peptide Sequences for TAAR3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9P1P4

UniProtKB/Swiss-Prot:

TAAR3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with TAAR3: view

Function for TAAR3 Gene

Molecular function for TAAR3 Gene

UniProtKB/Swiss-Prot Function:
Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the corresponding alcohols, isoamylalcohol and cyclohexanol. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity).

Gene Ontology (GO) - Molecular Function for TAAR3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001594 trace-amine receptor activity ISS --
GO:0004930 G-protein coupled receptor activity TAS 10684976
genes like me logo Genes that share ontologies with TAAR3: view

Phenotypes for TAAR3 Gene

GenomeRNAi human phenotypes for TAAR3:
genes like me logo Genes that share phenotypes with TAAR3: view

Animal Model Products

  • Taconic Biosciences Mouse Models for TAAR3

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TAAR3 Gene

Localization for TAAR3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAAR3 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TAAR3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TAAR3: view

No data available for Subcellular locations from COMPARTMENTS for TAAR3 Gene

Pathways & Interactions for TAAR3 Gene

genes like me logo Genes that share pathways with TAAR3: view

Pathways by source for TAAR3 Gene

Interacting Proteins for TAAR3 Gene

Gene Ontology (GO) - Biological Process for TAAR3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007606 sensory perception of chemical stimulus ISS --
genes like me logo Genes that share ontologies with TAAR3: view

No data available for SIGNOR curated interactions for TAAR3 Gene

Transcripts for TAAR3 Gene

mRNA/cDNA for TAAR3 Gene

(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TAAR3 Gene

Trace amine associated receptor 3 (gene/pseudogene):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TAAR3 Gene

No ASD Table

Relevant External Links for TAAR3 Gene

GeneLoc Exon Structure for
TAAR3
ECgene alternative splicing isoforms for
TAAR3

Expression for TAAR3 Gene

mRNA expression in normal human tissues for TAAR3 Gene

mRNA differential expression in normal tissues according to GTEx for TAAR3 Gene

This gene is overexpressed in Liver (x11.1) and Brain - Hypothalamus (x4.9).

NURSA nuclear receptor signaling pathways regulating expression of TAAR3 Gene:

TAAR3

SOURCE GeneReport for Unigene cluster for TAAR3 Gene:

Hs.730091

mRNA Expression by UniProt/SwissProt for TAAR3 Gene:

Q9P1P4-TAAR3_HUMAN
Tissue specificity: Not expressed in the pons, thalamus, globus pallidus, caudate, putamen or cerebellum.
genes like me logo Genes that share expression patterns with TAAR3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TAAR3 Gene

Orthologs for TAAR3 Gene

Evolution for TAAR3 Gene

ENSEMBL:
Gene Tree for TAAR3 (if available)
TreeFam:
Gene Tree for TAAR3 (if available)

No data available for Orthologs for TAAR3 Gene

Paralogs for TAAR3 Gene

(11) SIMAP similar genes for TAAR3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TAAR3: view

No data available for Paralogs for TAAR3 Gene

Variants for TAAR3 Gene

Sequence variations from dbSNP and Humsavar for TAAR3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10598040 -- 132,611,217(+) AAAAG(-/A)AAAAA upstream-variant-2KB
rs1081074 -- 132,610,318(-) GGCCT(G/T)CTTTT upstream-variant-2KB
rs1081075 -- 132,610,294(-) AGCAG(A/T)CTCTG upstream-variant-2KB
rs1081076 -- 132,610,220(-) GATGT(A/G)TATTC upstream-variant-2KB
rs1081077 -- 132,610,187(-) GTGAC(A/C)ATTTA upstream-variant-2KB

Relevant External Links for TAAR3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TAAR3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TAAR3 Gene

Disorders for TAAR3 Gene

Relevant External Links for TAAR3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TAAR3

No disorders were found for TAAR3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TAAR3 Gene

Publications for TAAR3 Gene

  1. Cloning and characterization of additional members of the G protein- coupled receptor family. (PMID: 10684976) Lee D.K. … Marchese A. (Biochim. Biophys. Acta 2000) 2 3 4 22 64
  2. International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature. (PMID: 19325074) Maguire J.J. … Davenport A.P. (Pharmacol. Rev. 2009) 2 3 22 64
  3. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. (PMID: 15718104) Lindemann L. … Hoener M.C. (Genomics 2005) 2 3 64
  4. High species variation within the repertoire of trace amine receptors. (PMID: 15891052) Gloriam D.E. … Fredriksson R. (Ann. N. Y. Acad. Sci. 2005) 2 3 64
  5. Discovery of a null mutation in a human trace amine receptor gene. (PMID: 14559210) Vanti W.B. … O'Dowd B.F. (Genomics 2003) 2 3 64

Products for TAAR3 Gene

Sources for TAAR3 Gene

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