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T Gene

protein-coding GIFtS: 62

GC06M166541

T, brachyury homolog (mouse)
(Previous name: T brachyury (mouse) homolog )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MGC104817 ^²
OTTHUMP00000017588 ^²
TF ^⁵
TFT ^²

Descriptions
T brachyury (mouse) homolog ^¹
T brachyury homolog ^²
T brachyury-like ^²
T protein ^³
T, brachyury homolog (mouse) ^²
transcription factor T ^²

External Ids
HGNC: 11515¹
Entrez Gene: 6862²
UniProtKB: O15178³
Ensembl: ENSG00000164458⁷

Search outside databases for aliases for T gene

Previous GC identifers: GC06M165924 GC06M166444 GC06M166481 GC06M166482

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for T:

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a

specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called

the T-box, and effects transcription of genes required for mesoderm formation and differentiation.

The protein is localized to notochord-derived cells. [provided by RefSeq]

UniProtKB/Swiss-Prot: BRAC_HUMAN, O15178

Function: Involved in the transcriptional regulation of genes required for mesoderm formation and

differentiation. Binds to a palindromic site (called T site) and activates gene transcription when

bound to such a site

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the T gene

Entrez Gene cytogenetic band: 6q27 Ensembl cytogenetic band: 6q27 HGNC cytogenetic band: 6q27

T Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M166541: (about GC identifiers)

Start:	166,490,785 bp from pter
End:	166,502,121 bp from pter
Size:	11,337 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_007422.13

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: BRAC_HUMAN, O15178 (See protein sequence)

Recommended Name: Brachyury protein

Size: 435 amino acids; 47443 Da

Subunit: Monomer (By similarity)

Subcellular location: Nucleus

REFSEQ proteins: NP_003172.1

ENSEMBL proteins:

ENSP00000296946 ENSP00000355836 ENSP00000355841

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Brachyury / Bry)
	Human Recombinant Proteins from Abnova (T)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

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Antibodies for T:

	Invitrogen Antibodies for T
	Millipore Mono- and Polyclonal Antibodies for the study of T
	Sigma-Aldrich Antibodies for T
	R&D Systems Antibodies for T (Brachyury)
	Antibodies from Abcam (Brachyury / Bry), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (T)
	Novus Biologicals Antibodies for T

Assays for T:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O15178

ProtoNet protein and cluster: O15178

2 Blocks protein families:

IPB001699 Transcription factor

IPB002070 Brachyury protein family signature

UniProtKB/Swiss-Prot: BRAC_HUMAN, O15178

Similarity: Contains 1 T-box DNA-binding domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (T)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (T)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003181

Applied Biosystems Silencer® siRNAs for T

Sigma-Aldrich siRNA for T

Sigma-Aldrich shRNA for T

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for T
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003181
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003181
untagged cDNA clone in CMV expression vector: NM_003181

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003181

UniProtKB/Swiss-Prot: BRAC_HUMAN, O15178

Function: Involved in the transcriptional regulation of genes required for mesoderm formation and

differentiation. Binds to a palindromic site (called T site) and activates gene transcription when

bound to such a site

Genatlas biochemistry entry for T:

murine T-box gene Tbx (T,brachyury) homolog,expressed in cells derived from the notochord,crucial

for mesoderm formation,no evidence of association with neural tube defects (NTD) in Netherlands

and U.K.

15/19 MGI mutant phenotypes (inferred from 37 alleles) (MGI details for T) (see all 19 ):

	behavior/neurological	craniofacial	digestive/alimentary	embryogenesis
growth/size	hearing/vestibular/ear	homeostasis/metabolism	lethality-postnatal	lethality-prenatal/perinatal
life span-post-weaning/aging	limbs/digits/tail	nervous system	no phenotypic analysis	other

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	NAS	8963900
GO:0005515	protein binding	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for T (Your Favorite Gene powered by Ingenuity)

Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency

GeneDecks T for the pathways selected above

About GeneDecksing

5/12 Interacting proteins for T (ENSP00000296946³) via UniProtKB, MINT, and/or STRING (see all 12 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GLDC	ENSP00000370740³	STRING (score=.996)
OCA2	ENSP00000346659³	STRING (score=.995)
AMT	ENSP00000273588³	STRING (score=.936)
DLD	ENSP00000205402³	STRING (score=.907)
GCSH	ENSP00000319531³	STRING (score=.907)

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5/13 Gene Ontology (GO) biological process terms (links to tree view) (see all 13 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001570	vasculogenesis	IEA	--
GO:0001756	somitogenesis	IEA	--
GO:0001839	neural plate morphogenesis	IEA	--
GO:0001843	neural tube closure	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for T

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (T)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (T)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003181

Sigma-Aldrich siRNA for T

Sigma-Aldrich shRNA for T

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003181

REFSEQ mRNAs for T gene:

NM_003181.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003181

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003181
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003181
                                 untagged cDNA clone in CMV expression vector: NM_003181

Additional cDNA sequence:

AJ001699.1 BC039877.1 BC098425.1

5 DOTS entries:

DT.97837890 DT.202766 DT.97837889 DT.100737559 DT.75161871

24/48 AceView cDNA sequences (see all 48 ):

NM_003181 BQ931406 AI341816 BG332916 BQ221957 BQ420570 BC039877 AI651456

BQ221790 BG490984 AW003327 BE785653 BQ925830 BF512284 BU192473 AI797600

BU164583 BF223613 BG333106 BQ951069 AI001036 AA994493 BQ924827 BQ222875

highest scoring ESTs for T:

AJ001699 BE789773 BG332994 BG333106 BG436736 BG436820 BQ927155 BU190437 AA994493 AI001036

Unigene Cluster for T:

T, brachyury homolog (mouse)

Hs.389457 [show with all ESTs]

Unigene Representative Sequence: NM_003181

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for T

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9a	·	9b
SP1:									-		-														-		-
SP2:
SP3:
SP4:							-		-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for T

3 Ensembl transcripts including schematic representations:

ENST00000296946 ENST00000366871 ENST00000366876

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

T expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for T

¹ / ² / ³

3 probe-sets matching T gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34966_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AJ001699	0.80	1.00	0.91	1
206524_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003181	0.60	1.00	0.82	1
206524_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGAAGCAGCA

SOURCE GeneReport for Unigene cluster: Hs.389457
Expression variation in blood from EXPOLDB for T

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for T gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	T¹	--	T, brachyury homolog (mouse)	89.43(n) 90.11(a)	403653 NM_001003092.1 NP_001003092.1
chimpanzee (Pan troglodytes)	T¹	--	T, brachyury homolog (mouse)	99.77(n) 99.54(a)	472186 XM_527563.2 XP_527563.2
cow (Bos taurus)	T¹	--	T, brachyury homolog (mouse)	88.28(n) 88.51(a)	524443 XM_864890.2 XP_869983.2
rat (Rattus norvegicus)	T¹	--	T, brachyury homolog (mouse)	86.64(n) 92.17(a)	292301 XM_217890.4 XP_217890.3
mouse (Mus musculus)	T^{1, 5}	17 (4.02 cM)⁵	brachyury^{1, 5}	85.71(n)¹ 91.71(a)¹	20997¹ NM_009309.2¹ NP_033335.1¹ BC120807⁵ BG065267⁵ (see all 6)

About this table Species with no ortholog for T

ENSEMBL Gene Tree for T

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for T gene

TBX19²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/108 NCBI SNPs in T are shown (see all 108 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 132)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs3099266^1,2	A,C,F,H	166501137(-)	`AGAGCG/AGGGAA`	1	--	ut5¹ ese³		5	EA EU WA	1890
	rs6928216^1,2	A,C,F,H	166503541(+)	`TTTCTA/GCTCTC`	1	--	ng3¹		7	EU EA WA NA	558
	rs3127328^1,2	A,C,F,H	166492035(+)	`GGCGCC/TGTTGC`	1	G/S	mis¹ ese³		12	NA EU EA WA	1006
	rs1867594^1,2	A,C,F,H	166503491(-)	`TGAAGT/CTGTAT`	1	--	ng3¹		12	MN NA EU EA WA	1162
	rs1056051^1,2	A,C,F,H	166491569(-)	`GGCTTC/ACAGAT`	1	--	ut3¹ ese³		8	EU EA WA NA	2058
	rs3099270^1,2	A,C,F,H	166491515(-)	`CGGTGG/AAAAAA`	1	--	ut3¹		8	EA NA EU WA	2058
	rs2305089^1,2	A,C,F,H	166499260(+)	`GTGGAC/TCCCCA`	1	G/D	mis¹ ese³		11	EA EU WA NA	2504
	rs1056053^1,2	A,C,F,H	166491433(-)	`AATTTA/GTAAAC`	1	--	ut3¹		9	EA NA EU WA	2128
	rs1867592^1,2	A,C,F,H	166503726(-)	`GAACCG/CAGGAA`	1	--	ng3¹ tfbs³		12	MN NA EU EA WA	1160
	rs1134481^1,2	A,C,F,H	166491154(-)	`CTGCAC/AAATAA`	1	--	ut3¹		4	EU EA WA	412

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HapMap Linkage Disequilibrium images for T (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 601397 disorders: 182940

UniProtKB/Swiss-Prot: BRAC_HUMAN, O15178

Genetic variations in T are associated with susceptibility to neural tube defects (NTD)

[MIM:182940]. NTD are common congenital malformations. Spina bifida, which results from

malformations in the caudal region of the neural tube, is compatible with life but associated with

significant morbidity, including lower limb paralysis

3 Novoseek disease relationships for T gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
colitis	26.85	1	17923080 (1), 11994418 (1)
inflammation	20.87	3	19412181 (1), 17723218 (1), 15498029 (1)
asthma	4.01	1	15604153 (1)

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Human Gene Mutation Database: T
Human Genome Epidemiology Navigator: T (0 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/82 PubMed articles for T gene (see all 82 ):

The human homolog T of the mouse T(Brachyury) gene; gene structure, cDNA sequence, and assignment to chromosome 6q27. (PubMed id 8963900)^{1, 2, 3, 4} Edwards Y.H....Sowden J. (1996)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
The human T locus and spina bifida risk. (PubMed id 15449172)^{1, 4} Jensen L.E....Mitchell L.E. (2004)
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. (PubMed id 18301055)³ Tirabosco R....Flanagan A.M. (2008)
Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis. (PubMed id 18820665)³ Oakley G.J....Seethala R.R. (2008)
A Missense T(Brachyury) Mutation Contributes to Vertebral Malformations. (PubMed id 18466071)³ Ghebranious N....Giampietro P.F. (2008)
Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions. (PubMed id 17273972)³ Zweier C.... Rauch A. (2007)
The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator. (PubMed id 12000749)³ Lingbeek M.E....van Lohuizen M. (2002)
Human T and risk for neural tube defects. (PubMed id 11897834)³ Richter B....Koch M.C. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6862	HGNC: 11515	AceView: T	Ensembl:ENSG00000164458	euGenes: HUgn6862
ECgene: T	H-InvDB: T

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for T
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for T:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for T-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for T		Antibodies for T
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for T		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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T Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for T

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Genomic Location
for T

Proteins
for T

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for T

Gene Function
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Pathways & Interactions
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Drugs & Compounds
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Medical News
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

T Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor T

Summariesfor T

Genomic Locationfor T

Proteinsfor T

Protein Domains/Familiesfor T

Gene Functionfor T

Pathways & Interactionsfor T

Drugs & Compoundsfor T

Transcriptsfor T

Expression for T

Orthologsfor T

Paralogsfor T

SNPs/Variantsfor T

Disorders & Mutationsfor T

Medical Newsfor T

Publicationsfor T

Search for T

Genome Databases showing T

Other Databases showing T

Specialized Databases showing T

Licensable Technologiesfor T

Servicesfor T

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for T

Summaries
for T

Genomic Location
for T

Proteins
for T

Protein Domains/
Families
for T

Gene Function
for T

Pathways & Interactions
for T

Drugs & Compounds
for T

Transcripts
for T

Expression
for T

Orthologs
for T

Paralogs
for T

SNPs/Variants
for T

Disorders & Mutations
for T

Medical News
for T

Publications
for T

Licensable Technologies
for T

Services
for T