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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SLC2A9 Gene

protein-coding GIFtS: 55
GCID: GC04M009772

solute carrier family 2 (facilitated glucose transporter),...

Explore 12 diseases affiliated with
SLC2A9 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 9¹ ²		UAQTL2² ⁵
GLUT9² ³ ⁵		Glut9¹
GLUTX¹ ²		Human Glucose Transporter-Like Protein-9²
URATv1¹ ²		Solute Carrier Family 2, Facilitated Glucose Transporter Member 9²
Glucose Transporter Type 9² ³		Urate Voltage-Driven Efflux Transporter 1²
GLUT-9² ³

External Ids:	HGNC: 13446¹	Entrez Gene: 56606²	Ensembl: ENSG00000109667⁷	OMIM: 606142⁵	UniProtKB: Q9NRM0³

Export aliases for SLC2A9 gene to outside databases

Previous GC identifers: GC04M009497 GC04M009778 GC04M009578 GC04M009504 GC04M009827 GC04M009162

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC2A9:

This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a

significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and

survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been

identified for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0

Function: Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports

glucose at low rate

Gene Wiki entry for SLC2A9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_006316.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SLC2A9 gene promoter:
Pax-5 Pax-6 Pax-2 Pax-2a LUN-1 Ik-3 POU2F1 POU2F1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC2A9 promoter sequence

Search SABiosciences Chromatin IP Primers for SLC2A9

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC2A9

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.1 Ensembl cytogenetic band: 4p16.1 HGNC cytogenetic band: 4p16.1

SLC2A9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC2A9 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M009772: view genomic region (about GC identifiers)

Start:	9,772,777 bp from pter	End:	10,056,560 bp from pter
Size:	283,784 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0 (See protein sequence)

Recommended Name: Solute carrier family 2, facilitated glucose transporter member 9

Size: 540 amino acids; 58702 Da

Subcellular location: Membrane; Multi-pass membrane protein

Secondary accessions: Q0VGC4 Q4W5D1 Q8WV30 Q96P00

Alternative splicing: 2 isoforms: Q9NRM0-1 Q9NRM0-2 (Variant in position: 17:A->T (in dbSNP:6820230))

Explore the universe of human proteins at neXtProt for SLC2A9: NX_Q9NRM0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NRM0

SLC2A9 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001001290.1 NP_064425.2

ENSEMBL proteins:

ENSP00000264784 ENSP00000422209 ENSP00000426800 ENSP00000311383

Reactome Protein details: Q9NRM0
Human Recombinant Protein Products for SLC2A9:

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	Uscn Proteins for SLC2A9

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005635	nuclear envelope	IEA	--
GO:0005886	plasma membrane	TAS	--
GO:0005887	integral to plasma membrane	IEA	--
GO:0016021	integral to membrane	NAS	10860667

SLC2A9 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC2A9 for domains About GeneDecksing

5 InterPro domains/families:

IPR005829 Sugar_transporter_CS

IPR005828 Sub_transporter

IPR003663 Sugar/inositol_transpt

IPR020846 MFS_dom

IPR016196 MFS_dom_general_subst_transpt

Graphical View of Domain Structure for InterPro Entry Q9NRM0

ProtoNet protein and cluster: Q9NRM0

2 Blocks protein families:

IPB003663 Sugar transporter signature

IPB005829 Sugar transporter superfamily

UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter

subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: GTR9_HUMAN, Q9NRM0

Function: Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports

glucose at low rate

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005351	sugar:hydrogen symporter activity	NAS	10860667
GO:0005355	glucose transmembrane transporter activity	IEA	--
GO:0022891	substrate-specific transmembrane transporter activity	--	--

SLC2A9 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for SLC2A9:

Decreased POU5F1-GFP protein e

6 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Slc2a9):

behavior/neurological	growth/size	homeostasis/metabolism	immune system	mortality/aging
renal/urinary system

SLC2A9 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Slc2a9^tm1.2Thor for SLC2A9

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SLC2A9

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC2A9

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

SLC-mediated transmembrane transport

	SLC-mediated transmembrane transport	1.00			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	0.38
	Transmembrane transport of small molecules	0.50

Facilitative Na+-independent glucose transporters

Facilitative Na+-independent glucose transporters

1.00

Class II GLUTs

0.33

Antigout Preparations Pathway, Pharmacodynamics

Antigout Preparations Pathway, Pharmacodynamics

1.00

PAK Pathway

Antioxidant Action of Vitamin-C

0.56

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SLC2A9

Antioxidant Action of Vitamin-C

5 Reactome Pathways for SLC2A9

	SLC-mediated transmembrane transport
	Transmembrane transport of small molecules
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Class II GLUTs
	Facilitative Na+-independent glucose transporters

1 PharmGKB Pathway for SLC2A9

Antigout Preparations Pathway, Pharmacodynamics

SLC2A9 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SLC2A9

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015758	glucose transport	NAS	10860667
GO:0046415	urate metabolic process	IMP	19503597
GO:0055085	transmembrane transport	TAS	--

SLC2A9 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

SLC2A9 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SLC2A9
4 Novoseek chemical compound relationships for SLC2A9 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cytochalasin b	59.5	9	14739288 (1)
2-deoxyglucose	54.5	5	14739288 (2)
glucose	47.7	16	20162745 (2), 15943951 (2), 10860667 (2), 11780753 (1) (see all 7)
fructose	47.3	1	11780753 (1)

Search CenterWatch for drugs/clinical trials and news about SLC2A9 / GTR9

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SLC2A9 gene (2 alternative transcripts):

NM_001001290.1 NM_020041.2

Unigene Cluster for SLC2A9:

Solute carrier family 2 (facilitated glucose transporter), member 9

Hs.656895 [show with all ESTs]

Unigene Representative Sequence: AK096819

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000508585 ENST00000503803 ENST00000512342 ENST00000503280 ENST00000264784(uc003gmc.3)

ENST00000506583(uc003gmd.3) ENST00000505104 ENST00000513129 ENST00000506839

ENST00000505506 ENST00000509214 ENST00000481042(uc003gme.1) ENST00000309065

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Additional cDNA sequence:

AF210317.1 AF421859.1 AK096819.1 AK310895.1 BC018897.2 BC110414.1

8 DOTS entries:

DT.110094 DT.100745107 DT.75100908 DT.439537 DT.307960 DT.75194662 DT.91907721 DT.65286643

10 AceView cDNA sequences:

AA228138 AW451509 AA227974 BE326892 AK025887 W48668 AI863532 W51903

BX111149 BE326912

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC2A9 About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15	^	16
SP1:					-		-										-		-
SP2:							-										-		-
SP3:
SP4:											-

ECgene alternative splicing isoforms for SLC2A9

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SLC2A9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

SLC2A9 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Maxillary Process

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SLC2A9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC2A9

SOURCE GeneReport for Unigene cluster: Hs.656895

UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0

Tissue specificity: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and

placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage.

Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and

isoform 2 are detected in kidney membrane (at protein level)

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC2A9 gene from 9/23 species (see all 23) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Slc2a9^{1 , 5}	solute carrier family 2 (facilitated glucose transporter), more^{1, 5}	82.27(n)¹ 84.97(a)¹		5 (20.43 cM)⁵ 117591¹ NM_001102414.1¹ NP_001095884.1¹ 38349273⁵
chicken (Gallus gallus)	Aves	SLC2A9¹	solute carrier family 2 (facilitated glucose transporter), more	68.35(n) 74.8(a)		422843 XM_420789.3 XP_420789.3
lizard (Anolis carolinensis)	Reptilia	--	--	64(a)	1 ↔ 1	GL343236.1(469695-511994)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.17199²	Transcribed sequence with weak similarity to protein more	74.42(n)		BX760056.1
zebrafish (Danio rerio)	Actinopterygii	CA496350.1²	--	72.32(n)		CA496350.1
fruit fly (Drosophila melanogaster)	Insecta	sut2³	sugar porter	27(a) (best of 2)		--
worm (Caenorhabditis elegans)	Secernentea	K08F9.1³	glucose transporter	25(a) (best of 3)		V(15139997-15142169) --
thale cress (Arabidopsis thaliana)	eudicotyledons	SGB1⁶ PGLCT⁶ (see all 4)	Plastidic glucose transporter 4 (see all 4)	23(a) 22(a) (see all 4)	many ↔ many many ↔ many (see all 4)	1(30022260-30027443) 5(5272557-5275815)
rice (Oryza sativa)	Liliopsida	-- -- (see all 3)	transporter family protein, putative, expressed (see all 3)	23(a) 21(a) (see all 3)	many ↔ many many ↔ many (see all 3)	2(10074579-10081510) 9(13665486-13670301)

ENSEMBL Gene Tree for SLC2A9 (if available)
TreeFam Gene Tree for SLC2A9 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SLC2A9 gene

ENSG00000251357² SLC2A5² SLC2A7² SLC2A3² SLC2A14² SLC2A2² SLC2A1² SLC2A4²

SLC2A11²

11 SIMAP similar genes for SLC2A9 using alignment to 2 protein entries: GTR9_HUMAN (see all proteins):

SLC2A5 SLC2A11 SLC2A7 SLC2A11-a SLC2A11-c SLC2A1

SLC2A4 SLC2A3 SLC2A14 SLC2A2 SLC2A10

SLC2A9 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0

Polymorphism: Genetic variations in SLC2A9 influence the variance in serum uric acid concentrations and define the

serum uric acid concentration quantitative trait locus 2 (UAQTL2) [MIM:612076]. Excess serum accumulation of uric acid

can lead to the development of gout

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76960053^1,2	C	--	9261201(+)	`ACTCTC/TGTCTG`	1	--	int¹		0	--	--	--	--
rs938557^1,2	C,F,H	--	9827556(+)	`TGGGAC/TCCAGG`	2	--	ds500¹		27		MN NS EA NA WA CSA	2539
rs180859433^1,2		--	9827629(+)	`AATCCC/GTTGAG`	2	--	ds500¹		0	--	--	--	--
rs199527634^1,2		--	9827684(+)	`CTACT-/ATT TCCCCAATTTC`	2	--	ds500¹		0	--	--	--	--
rs150828093^1,2		--	9827730(+)	`AGAAGG/TCAGGT`	2	--	ds500¹		0	--	--	--	--
rs75815764^1,2	C,F	--	9827738(+)	`GGTCAT/CCTACC`	2	--	ds500¹		1		WA	118
rs139283693^1,2		--	9827767(+)	`GTCTAA/CTGAAA`	2	--	ds500¹		0	--	--	--	--
rs144294717^1,2		--	9827911(+)	`CAATTA/CATTTA`	2	--	ut3¹		0	--	--	--	--
rs200281070^1,2		--	9827978(+)	`GACAAC/TCCTGT`	2	--	ut3¹		0	--	--	--	--
rs185963043^1,2	C	--	9828019(+)	`AAACTG/TGTTAA`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SLC2A9 (9772777 - 10022777 bp, first 250kb of SLC2A9)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 17 variations for SLC2A9
6 CNVs: 63747 51496 31164 2070 8443 3479
11 Indels: 41763 12404 40601 98624 63748 40602 12405 46721 12406 98625 46720
Human Gene Mutation Database (HGMD): SLC2A9

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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SLC2A9 for disorders           About GeneDecksing

OMIM gene information: 606142
OMIM disorders: 612076
UniProtKB/Swiss-Prot: GTR9_HUMAN, Q9NRM0

Defects in SLC2A9 are the cause of hypouricemia renal type 2 (RHUC2) [MIM:612076]. A disorder characterized by

impaired uric acid reabsorption at the apical membrane of proximal renal tubule cells, and high urinary urate

excretion. Patients often appear asymptomatic, but may be subject to exercise-induced acute renal failure, chronic

renal dysfunction and nephrolithiasis

12 diseases for SLC2A9: About MalaCards

uric acid concentration, serum, qtl 2 hypouricemia epidural abscess type 2 diabetes mellitus

renal hypouricemia diabetes mellitus gout hyperuricemia

nephrolithiasis parkinson's disease arthritis pancreatitis

3 diseases from the University of Copenhagen DISEASES database for SLC2A9:

Hyperuricemia Nephrolithiasis DOID:13189

Human Genome Epidemiology (HuGE) Navigator: SLC2A9 (28 documents)

Export disorders for SLC2A9 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SLC2A9 gene, integrated from 9 sources (see all 73):
(articles sorted by number of sources associating them with SLC2A9)

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world of online information

Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9). (PubMed id 10860667)^{1, 2, 3, 9} Phay J.E.... Moley J.F. (2000)
Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking. (PubMed id 14739288)^{1, 2, 9} Augustin R....Moley K.H. (2004)
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. (PubMed id 19026395)^{1, 2, 9} Matsuo H....Shinomiya N. (2008)
Human articular chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9. (PubMed id 11991658)^{1, 2, 9} Mobasheri A.... Carter S.D. (2002)
Homozygous SLC2A9 mutations cause severe renal hypour icemia. (PubMed id 19926891)^{1, 2, 9} Dinour D....Holtzman E.J. (2010)
Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2. (PubMed id 21810765)^{1, 2} Dinour D....Holtzman E.J. (2011)
SLC2A9 influences uric acid concentrations with pronounced sex- specific effects. (PubMed id 18327256)^{1, 2} Doering A.... Meisinger C. (2008)
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. (PubMed id 18327257)^{1, 2} Vitart V....Wright A.F. (2008)
A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity. (PubMed id 17710649)^{1, 3} Manolescu A.R....Cheeseman C. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 56606	HGNC: 13446	AceView: SLC2A9.1	Ensembl:ENSG00000109667	euGenes: HUgn56606
ECgene: SLC2A9	H-InvDB: SLC2A9

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SLC2A9	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLC2A9 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SLC2A9 gene:
Search GeneIP for patents involving SLC2A9

GeneCards and IP:
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