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SZT2 Gene

protein-coding   GIFtS: 42
GCID: GC01P043890

Seizure Threshold 2 Homolog (Mouse)

(Previous names: chromosome 1 open reading frame 84, KIAA0467)
(Previous symbols: C1orf84, KIAA0467)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Seizure Threshold 2 Homolog (Mouse)1 2     Seizure Threshold 2 Homolog A (Mouse)1
KIAA04671 2 3 5     Seizure Threshold 2 Homolog B (Mouse)1
C1orf841 2 3     RP11-506B15.12
Seizure Threshold 2 Protein Homolog2 3     SZT2A2
EIEE182 5     SZT2B2
Chromosome 1 Open Reading Frame 841     Protein SZT22

External Ids:    HGNC: 290401   Entrez Gene: 233342   Ensembl: ENSG000001981987   OMIM: 6154635   UniProtKB: Q5T0113   

Export aliases for SZT2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SZT2 Gene:
The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as
well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative
stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD
activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance
epileptogenesis. (provided by RefSeq, Jun 2011)

GeneCards Summary for SZT2 Gene:
SZT2 (seizure threshold 2 homolog (mouse)) is a protein-coding gene. Diseases associated with SZT2 include epileptic encephalopathy, early infantile, 18.

UniProtKB/Swiss-Prot: SZT2_HUMAN, Q5T011
Function: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective
effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and
confer low seizure threshold (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SZT2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SZT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SZT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.2   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34.2

SZT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SZT2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P043890:  view genomic region     (about GC identifiers)

Start:
43,855,553 bp from pter      End:
43,919,918 bp from pter
Size:
64,366 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SZT2_HUMAN, Q5T011 (See protein sequence)
Recommended Name: Protein SZT2  
Size: 3432 amino acids; 378029 Da
Sequence caution: Sequence=AAH52802.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI51233.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB15649.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC03755.1; Type=Miscellaneous
discrepancy; Note=Probable cloning artifact; Sequence=BAC86771.1; Type=Miscellaneous discrepancy; Note=Probable
cloning artifact; Sequence=BF926328; Type=Frameshift; Positions=Several; Sequence=BF926328; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part; Sequence=BU101724;
Type=Frameshift; Positions=287; Sequence=CAI14886.2; Type=Erroneous gene model prediction; Sequence=CAI23384.1;
Type=Erroneous gene model prediction;
Secondary accessions: A0PJK5 A7E2X4 O75055 Q5JUY7 Q5T012 Q5XKC7 Q6ZNI8 Q6ZT24 Q7Z636 Q8NAY9
Q9H5H7 Q9UFQ8
Alternative splicing: 4 isoforms:  Q5T011-1   Q5T011-4   Q5T011-5   Q5T011-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SZT2: NX_Q5T011

Explore proteomics data for SZT2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SZT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056099.3  
    ENSEMBL proteins: 
     ENSP00000361528   ENSP00000386070   ENSP00000457168   ENSP00000312234   ENSP00000361519  

    SZT2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q5T011


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SZT2_HUMAN, Q5T011
    Function: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective
    effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and
    confer low seizure threshold (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    SZT2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SZT2:
     Downregulation of NF-kappaB pa  Increased number of cells in m 

         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Szt2):
     behavior/neurological  integument  mortality/aging  nervous system  pigmentation 

    SZT2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SZT2
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    miRNA
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    miRTarBase miRNAs that target SZT2:
    hsa-mir-423-3p (MIRT042583)

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    Selected qRT-PCR Assays for microRNAs that regulate SZT2 (see all 9):
    hsa-miR-485-5p hsa-miR-642a hsa-miR-516b hsa-miR-1291 hsa-miR-9 hsa-miR-2355-5p hsa-miR-491-5p hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SZT2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SZT2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SZT2_HUMAN, Q5T011: Peroxisome (By similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005777peroxisome ISS--

    SZT2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SZT2
    Interactions:

        Search GeneGlobe Interaction Network for SZT2

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007417central nervous system development ISS--
    GO:0009790embryo development ISS--
    GO:0009791post-embryonic development ISS--
    GO:0021540corpus callosum morphogenesis IMP--
    GO:0043473pigmentation IEA--

    SZT2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SZT2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SZT2 gene (4 alternative transcripts): 
    NM_015284.3  NM_001012960.1  NM_001012961.1  NM_182518.2  

    Unigene Cluster for SZT2:

    Seizure threshold 2 homolog (mouse)
    Hs.643560  [show with all ESTs]
    Unigene Representative Sequence: NM_015284
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372450(uc001cjh.3) ENST00000357658 ENST00000406439(uc001cji.1)
    ENST00000562955(uc009vws.1 uc001cjk.2) ENST00000470139 ENST00000478140
    ENST00000470897 ENST00000471177 ENST00000460536(uc001cjl.2) ENST00000310739
    ENST00000372442
    miRNA
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    Block miRNA regulation of human, mouse, rat SZT2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SZT2 (see all 9):
    hsa-miR-485-5p hsa-miR-642a hsa-miR-516b hsa-miR-1291 hsa-miR-9 hsa-miR-2355-5p hsa-miR-491-5p hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SZT2 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SZT2
      QuantiFast Probe-based Assays in human, mouse, rat SZT2

    Additional mRNA sequence: 

    AB007936.2 AK001249.2 AK027078.1 AK126972.1 AL117402.1 BC017576.1 BC041069.1 BC051343.1 
    BC052802.1 BC082968.1 BC151232.1 

    17 DOTS entries:

    DT.92447357  DT.75101610  DT.75101209  DT.92068022  DT.40197185  DT.100014434  DT.40257700  DT.92447359 
    DT.100774763  DT.121362202  DT.121362286  DT.91687161  DT.91745030  DT.102842726  DT.95238919  DT.95266780 
    DT.99930908 

    Selected AceView cDNA sequences (see all 227):

    AI701486 BX112506 AL117402 CD672373 BX500023 NM_015284 BQ952043 CA450365 
    BC041069 BU528173 AA731490 AB007936 BI003868 AK131107 AA938452 AU124431 
    AK027078 BF525944 AW196912 C15468 BM562023 BU527625 AW674579 BU622383 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SZT2 (see all 19)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b · 14c ^ 15a · 15b · 15c ^ 16 ^ 17 ^ 18 ^ 19a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19b ^ 20a · 20b ^ 21 ^ 22a · 22b ^ 23a · 23b ^ 24a · 24b · 24c ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31a · 31b · 31c ^ 32a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 32b ^ 33a · 33b ^ 34a · 34b ^ 35 ^ 36 ^ 37
    SP1:                                                
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for SZT2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SZT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTACTGGCAT
    SZT2 Expression
    About this image

    SZT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SZT2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.643560

    UniProtKB/Swiss-Prot: SZT2_HUMAN, Q5T011
    Tissue specificity: Expressed in the brain, predominantly in the parietal and frontal cortex, as well as in dorsal
    root ganglia. Expressed in peripheral white blood cells

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SZT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SZT2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Szt21 , 5 seizure threshold 21, 5 87.46(n)1
    92.09(a)1
      4 (54.61 cM)5
    2306761  NM_198170.41  NP_937813.31 
     1183627435 
    chicken
    (Gallus gallus)
    Aves SZT21 seizure threshold 2 homolog (mouse) 67.01(n)
    67.42(a)
      424566  NM_001277766.1  NP_001264695.1 
    lizard
    (Anolis carolinensis)
    Reptilia SZT26
    seizure threshold 2 homolog (mouse)
    57(a)
    1 ↔ 1
    4(107378601-107445024)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia szt21 seizure threshold 2 homolog (mouse) 61.59(n)
    62.7(a)
      100496044  XM_002931601.2  XP_002931647.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5719861 protein SZT2-like 60.91(n)
    59.74(a)
      571986  XM_695635.6  XP_700727.6 
    worm
    (Caenorhabditis elegans)
    Secernentea F54B3.16
    Protein F54B3.1, isoform a (F54B3.1) mRNA, complet...
    16(a)
    1 ↔ 1
    II(10251266-10268175) WBGene00010013


    ENSEMBL Gene Tree for SZT2 (if available)
    TreeFam Gene Tree for SZT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SZT2 (see all 1687)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2004538521,2
    Cuntested143987576(+) TGTGTC/G/TGCCCC 2 S W mis11EU 1315
    rs1390271711,2
    C,Funtested143987582(+) GCCCCC/TGGGAG 2 P L mis12Minor allele frequency- T:0.00NA EU 5875
    rs1860433381,2
    --41976886(+) ACTCCA/GTCTCA 1 -- int10--------
    rs728819671,2
    C,F--43858297(+) AGCCAG/AATAGT 1 -- int12Minor allele frequency- A:0.03WA 120
    rs728819721,2
    C,F--43860359(+) AGCCTC/GACCAG 1 -- int13Minor allele frequency- G:0.08WA EA 240
    rs1131686001,2
    C,F--43879269(+) CATATG/ATACAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs355331731,2
    C--43879396(+) TATTT-/ATTT  
            
    GTGAG
    1 -- int10--------
    rs124081121,2
    C,H--43879576(+) actgaC/Ttacag 1 -- int10--------
    rs344643081,2
    C--43911163(+) GCCAT-/CCCCCCC 1 -- int10--------
    rs1149128961,2
    F--43932325(+) AGAGAA/TGTCAA 1 -- us2k11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for SZT2 (43855553 - 43919918 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for SZT2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747586CNV Deletion23290073
    esv3099CNV Deletion18987735
    esv2400702CNV Deletion18987734
    esv2747597CNV Deletion23290073
    esv2560782CNV Deletion19546169
    nsv527798CNV Loss19592680
    nsv159253CNV Loss16902084
    nsv438377CNV Loss16468122
    esv5810CNV Loss19470904

    Human Gene Mutation Database (HGMD): SZT2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SZT2
    DNA2.0 Custom Variant and Variant Library Synthesis for SZT2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615463   
    OMIM disorders: 615476  
    UniProtKB/Swiss-Prot: SZT2_HUMAN, Q5T011
  • Epileptic encephalopathy, early infantile, 18 (EIEE18) [MIM:615476]: A severe autosomal recessive
    neurologic disorder characterized by lack of psychomotor development apparent from birth, dysmorphic facial
    features, early onset of refractory seizures, and thick corpus callosum and persistent cavum septum pellucidum on
    brain imaging. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 1 disease for SZT2:    
    About MalaCards
    epileptic encephalopathy, early infantile, 18


    SZT2 for disorders           About GeneDecksing


    Export disorders for SZT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SZT2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SZT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2, 3 Seki N.... Ohara O. (DNA Res. 1997)
    2. Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum. (PubMed id 23932106)1, 2 Basel-Vanagaite L.... Borck G. (Am. J. Hum. Genet. 2013)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Bridging expressed sequence alignments through targeted cDNA sequencing. (PubMed id 15028280)1, 2 Xie H.... Gill-More R. (Genomics 2004)
    7. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1, 2 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. A novel giant peroxisomal superoxide dismutase motif-containing protein. (PubMed id 20045724)2 Toutzaris D.... Methner A. (Free Radic. Biol. Med. 2010)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23334 HGNC: 29040 AceView: KIAA0467 Ensembl:ENSG00000198198 euGenes: HUgn23334
    ECgene: SZT2 H-InvDB: SZT2

    (According to HUGE)
    About This Section

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    HUGE: KIAA0467

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SZT2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SZT2 gene:
    Search GeneIP for patents involving SZT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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