Aliases for SZT2 Gene
External Ids for SZT2 Gene
Previous HGNC Symbols for SZT2 Gene
Previous GeneCards Identifiers for SZT2 Gene
The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]
GeneCards Summary for SZT2 Gene
UniProtKB/Swiss-Prot for SZT2 Gene
Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold (By similarity).