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Aliases for SZRD1 Gene

Aliases for SZRD1 Gene

  • SUZ RNA Binding Domain Containing 1 2 3
  • Putative MAPK-Activating Protein PM18/PM20/PM22 3 4
  • C1orf144 3 4
  • Putative MAPK Activating Protein PM20,PM21 3
  • Chromosome 1 Open Reading Frame 144 2
  • SUZ Domain-Containing Protein 1 3
  • UPF0485 Protein C1orf144 3

External Ids for SZRD1 Gene

Previous HGNC Symbols for SZRD1 Gene

  • C1orf144

Previous GeneCards Identifiers for SZRD1 Gene

  • GC01P016681

Summaries for SZRD1 Gene

GeneCards Summary for SZRD1 Gene

SZRD1 (SUZ RNA Binding Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SZRD1 Gene

Genomics for SZRD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SZRD1 Gene

16,352,575 bp from pter
16,398,148 bp from pter
45,574 bases
Plus strand

Genomic View for SZRD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SZRD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SZRD1 Gene

No data available for Regulatory Elements for SZRD1 Gene

Proteins for SZRD1 Gene

  • Protein details for SZRD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    SUZ domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A8MXJ2
    • C9K0U0
    • Q7Z424
    • Q8IVM2
    • Q8TBV3
    • Q9Y403

    Protein attributes for SZRD1 Gene

    152 amino acids
    Molecular mass:
    16997 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAB43245.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAC82500.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for SZRD1 Gene


neXtProt entry for SZRD1 Gene

Proteomics data for SZRD1 Gene at MOPED

Post-translational modifications for SZRD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SZRD1 Gene

No data available for DME Specific Peptides for SZRD1 Gene

Domains for SZRD1 Gene

Protein Domains for SZRD1 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SUZ domain.
  • Belongs to the SZRD1 family.
  • Contains 1 SUZ domain.
  • Belongs to the SZRD1 family.
genes like me logo Genes that share domains with SZRD1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SZRD1 Gene

Function for SZRD1 Gene

Phenotypes for SZRD1 Gene

GenomeRNAi human phenotypes for SZRD1:
genes like me logo Genes that share phenotypes with SZRD1: view

Animal Model Products

miRNA for SZRD1 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SZRD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SZRD1 Gene

Localization for SZRD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SZRD1 Gene

Pathways for SZRD1 Gene

SuperPathways for SZRD1 Gene

No Data Available

Interacting Proteins for SZRD1 Gene

Gene Ontology (GO) - Biological Process for SZRD1 Gene


No data available for Pathways by source for SZRD1 Gene

Transcripts for SZRD1 Gene

Unigene Clusters for SZRD1 Gene

SUZ RNA binding domain containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SZRD1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SZRD1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - -
SP2: - - -
SP3: - - -
SP4: - - -
SP5: - - -
SP6: - - - - -
SP7: - - - - -
SP8: - - - - - -

Relevant External Links for SZRD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SZRD1 Gene

mRNA expression in normal human tissues for SZRD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for SZRD1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (15.0), Heart (11.1), and Bone (6.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SZRD1 Gene

SOURCE GeneReport for Unigene cluster for SZRD1 Gene Hs.252967

genes like me logo Genes that share expressions with SZRD1: view

Expression partners for SZRD1 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SZRD1 Gene

Orthologs for SZRD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SZRD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SZRD1 35
  • 94.96 (n)
  • 98.03 (a)
SZRD1 36
  • 98 (a)
(Canis familiaris)
Mammalia SZRD1 35
  • 96.05 (n)
  • 98.68 (a)
SZRD1 36
  • 99 (a)
(Mus musculus)
Mammalia Szrd1 35
  • 94.96 (n)
  • 97.37 (a)
Szrd1 16
Szrd1 36
  • 97 (a)
(Pan troglodytes)
Mammalia SZRD1 35
  • 100 (n)
  • 100 (a)
C1ORF144 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Szrd1 35
  • 95.39 (n)
  • 97.37 (a)
(Monodelphis domestica)
Mammalia SZRD1 36
  • 97 (a)
(Ornithorhynchus anatinus)
Mammalia SZRD1 36
  • 88 (a)
(Gallus gallus)
Aves C21H1ORF144 35
  • 85.96 (n)
  • 93.42 (a)
SZRD1 36
  • 93 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC76116 35
szrd1 35
  • 76.32 (n)
  • 84.21 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.3649 35
(Danio rerio)
Actinopterygii szrd1 35
  • 64.25 (n)
  • 67.11 (a)
wufb15h05 35
szrd1 36
  • 63 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9729 35
Species with no ortholog for SZRD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SZRD1 Gene

Gene Tree for SZRD1 (if available)
Gene Tree for SZRD1 (if available)

Paralogs for SZRD1 Gene Pseudogenes for SZRD1 Gene

genes like me logo Genes that share paralogs with SZRD1: view

No data available for Paralogs for SZRD1 Gene

Variants for SZRD1 Gene

Sequence variations from dbSNP and Humsavar for SZRD1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs566724 -- 16,368,279(+) CTTAA(A/G)GGTTT intron-variant
rs612727 -- 16,389,879(-) CAAAG(A/G)AGTCC intron-variant
rs635120 -- 16,376,953(-) GCTCA(C/T)GCACC intron-variant
rs2001913 -- 16,369,422(+) ATTGG(C/T)AGCAT intron-variant
rs2271515 -- 16,391,190(+) AGAAG(A/G)GAGAT intron-variant

Relevant External Links for SZRD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SZRD1 Gene

Disorders for SZRD1 Gene

No disorders were found for SZRD1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SZRD1 Gene

Publications for SZRD1 Gene

  1. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PMID: 12761501) Matsuda A. … Sugano S. (Oncogene 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for SZRD1 Gene

Sources for SZRD1 Gene

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