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SYTL5 Gene

protein-coding   GIFtS: 55
GCID: GC0XP037865

Synaptotagmin-Like 5

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synaptotagmin-Like 51 2
Exophilin 91 2
slp52
Synaptotagmin-Like Protein 52
SLP53

External Ids:    HGNC: 155891   Entrez Gene: 941222   Ensembl: ENSG000001470417   UniProtKB: Q8TDW53   

Export aliases for SYTL5 gene to outside databases

Previous GC identifers: GC0XP035998 GC0XP036180 GC0XP036737 GC0XP036924 GC0XP036923 GC0XP037622 GC0XP037750 GC0XP037778 GC0XP035611


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SYTL5 Gene:
The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique
homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding
site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and
liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by
RefSeq, Sep 2009)

GeneCards Summary for SYTL5 Gene:
SYTL5 (synaptotagmin-like 5) is a protein-coding gene. GO annotations related to this gene include Rab GTPase binding. An important paralog of this gene is SYTL4.

UniProtKB/Swiss-Prot: SYTL5_HUMAN, Q8TDW5
Function: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_079573.5  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYTL5 gene promoter:
         HOXA9B   HOXA9   CUTL1   Meis-1b   Evi-1   MEF-2A   Pax-3   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYTL5 promoter sequence
   Search Chromatin IP Primers for SYTL5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYTL5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp21.1   Ensembl cytogenetic band:  Xp11.4   HGNC cytogenetic band: Xp21.1

SYTL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYTL5 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP037865:  view genomic region     (about GC identifiers)

Start:
37,865,835 bp from pter      End:
37,988,073 bp from pter
Size:
122,239 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SYTL5_HUMAN, Q8TDW5 (See protein sequence)
Recommended Name: Synaptotagmin-like protein 5  
Size: 730 amino acids; 81523 Da
Subunit: Binds RAB27A that has been activated by GTP-binding, and possibly also RAB3A and RAB6A
Secondary accessions: A2RRF2
Alternative splicing: 2 isoforms:  Q8TDW5-1   Q8TDW5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYTL5: NX_Q8TDW5

Explore proteomics data for SYTL5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SYTL5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001156806.1  NP_001156807.1  NP_620135.1  

    ENSEMBL proteins: 
     ENSP00000297875   ENSP00000350657   ENSP00000395220  

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    Cloud-Clone Corp. Proteins for SYTL5

     
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    antibodies-online proteins for SYTL5 (3 products) 

     
    antibodies-online peptides for SYTL5

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR028702 Slp5
     IPR013083 Znf_RING/FYVE/PHD
     IPR011011 Znf_FYVE_PHD
     IPR000008 C2_dom
     IPR010911 Znf_FYVE-typ

    Graphical View of Domain Structure for InterPro Entry Q8TDW5

    ProtoNet protein and cluster: Q8TDW5

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: SYTL5_HUMAN, Q8TDW5
    Similarity: Contains 2 C2 domains
    Similarity: Contains 1 FYVE-type zinc finger
    Similarity: Contains 1 RabBD (Rab-binding) domain


    Find genes that share domains with SYTL5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYTL5_HUMAN, Q8TDW5
    Function: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12051743
    GO:0017137Rab GTPase binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with SYTL5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SYTL5:
     Decreased CXCL12 induced migra 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SYTL5

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    Selected qRT-PCR Assays for microRNAs that regulate SYTL5 (see all 9):
    hsa-miR-3163 hsa-miR-582-3p hsa-miR-607 hsa-miR-4328 hsa-miR-125a-3p hsa-miR-539 hsa-miR-1305 hsa-miR-489
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SYTL5_HUMAN, Q8TDW5: Membrane; Peripheral membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    cytoskeleton1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane IEA--

    Find genes that share ontologies with SYTL5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SYTL5 About    
    See pathways by source

    SuperPathContained pathways About
    1wtCFTR and deltaF508 traffic Late endosome and Lysosome norm and CF
    wtCFTR and deltaF508 traffic Late endosome and Lysosome norm and CF
    2Deregulation of Rab and Rab Effector Genes in Bladder Cancer
    Deregulation of Rab and Rab Effector Genes in Bladder Cancer

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for SYTL5
        wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)

    1 BioSystems Pathway for SYTL5
        Deregulation of Rab and Rab Effector Genes in Bladder Cancer


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYTL5
    Interactions:

        GeneGlobe Interaction Network for SYTL5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for SYTL5 (Q8TDW51, 3 ENSP000002978754) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB3AP203363, ENSP000002222564I2D: score=2 STRING: ENSP00000222256
    RAB27AP511593, ENSP000003377614I2D: score=5 STRING: ENSP00000337761
    RAB6AP203403, ENSP000003114494I2D: score=2 STRING: ENSP00000311449
    RAB5CENSP000003456894STRING: ENSP00000345689
    STXBP2ENSP000002212834STRING: ENSP00000221283
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--
    GO:0006887exocytosis IEA--

    Find genes that share ontologies with SYTL5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYTL5

    1 HMDB Compound for SYTL5    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYTL5 gene (3 alternative transcripts): 
    NM_001163334.1  NM_001163335.1  NM_138780.2  

    Unigene Cluster for SYTL5:

    Synaptotagmin-like 5
    Hs.662334  [show with all ESTs]
    Unigene Representative Sequence: BX647688
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297875 ENST00000357972(uc004ddu.3 uc004ddv.3) ENST00000456733(uc004ddx.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SYTL5 (see all 9):
    hsa-miR-3163 hsa-miR-582-3p hsa-miR-607 hsa-miR-4328 hsa-miR-125a-3p hsa-miR-539 hsa-miR-1305 hsa-miR-489
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    Additional mRNA sequence: 

    AB080222.1 AK125106.1 BC131585.1 BX647688.1 

    3 DOTS entries:

    DT.101979722  DT.40119152  DT.121282259 

    7 AceView cDNA sequences:

    AL708101 CD652837 AK125106 AB080222 NM_138780 BX647688 BU177061 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SYTL5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b
    SP1:              -                                                                                                                     
    SP2:              -     -                                                                                                               
    SP3:                    -                                                                                                               


    ECgene alternative splicing isoforms for SYTL5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYTL5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGAGTTCATA
    SYTL5 Expression
    About this image


    SYTL5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     NULL (Uncategorized)    fully expand to see all 3 entries
             Mesoderm-like cells
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
    SYTL5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYTL5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.662334

    UniProtKB/Swiss-Prot: SYTL5_HUMAN, Q8TDW5
    Tissue specificity: Highly expressed in placenta and liver

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SYTL5 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sytl51 , 5 synaptotagmin-like 51, 5 86.06(n)1
    84.55(a)1
      X (4.62 cM)5
    2366431  NM_177704.21  NP_808372.11 
     98856225 
    chicken
    (Gallus gallus)
    Aves SYTL51 synaptotagmin-like 5 71.05(n)
    69.3(a)
      427990  XM_003640483.2  XP_003640531.1 
    lizard
    (Anolis carolinensis)
    Reptilia SYTL56
    synaptotagmin-like 5
    64(a)
    1 ↔ 1
    3(132272496-132349089)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3986722 hypothetical protein LOC398672 72.82(n)    BC054989.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sytl51 synaptotagmin-like 5 58.71(n)
    55.64(a)
      558324  XM_681527.6  XP_686619.6 


    ENSEMBL Gene Tree for SYTL5 (if available)
    TreeFam Gene Tree for SYTL5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYTL5 gene
    SYTL42  DOC2B2  SYTL12  DOC2A2  SYTL32  RPH3A2  SYTL22  
    2 SIMAP similar genes for SYTL5 using alignment to 1 protein entry:     SYTL5_HUMAN:
    SYTL1    SYTL4

    Find genes that share paralogs with SYTL5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYTL5 (see all 1884)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1881625211,2
    --37780390(+) AATGAA/GATTCT 2 -- us2k10--------
    rs1913824971,2
    --37780399(+) CTGTCA/GTTTGC 2 -- us2k10--------
    rs1828046251,2
    --37780454(+) GCCAGA/GCACAG 2 -- us2k10--------
    rs78857041,2
    C,F,A,H--37780468(+) aaaaaA/Ttttgc 2 -- us2k1 tfbs35--NA WA 144
    rs1483095011,2
    C--37780687(+) TGTGCA/GTTTTA 2 -- us2k10--------
    rs1912949931,2
    --37780708(+) GACAGC/TATGAT 2 -- us2k10--------
    rs59642781,2
    C,F,H--37780713(+) tatgaT/Ctgtat 2 -- us2k14Minor allele frequency- C:0.01NS EA 404
    rs1835248821,2
    --37780768(+) ATTTAC/TCCTGA 2 -- us2k10--------
    rs1878120011,2
    --37780879(+) AAAACC/TCAGCC 2 -- us2k10--------
    rs1923385081,2
    C--37780907(+) GGAGAC/TAGAAT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SYTL5 (37865835 - 37988073 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SYTL5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv518029CNV Gain19592680
    esv2752323CNV Gain17911159
    nsv519012CNV Gain19592680

    Human Gene Mutation Database (HGMD): SYTL5
    Locus Specific Mutation Databases (LSDB): SYTL5

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYTL5
    DNA2.0 Custom Variant and Variant Library Synthesis for SYTL5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with SYTL5           About GenesLikeMe


    Export disorders for SYTL5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYTL5 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SYTL5)
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    1. Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. (PubMed id 12051743)1, 2 Kuroda T.S.... Mikoshiba K. (Biochem. Biophys. Res. Commun. 2002)
    2. Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism. (PubMed id 16630545)1, 9 Saxena S.K....Fukuda M. (Biochem. Biophys. Res. Commun. 2006)
    3. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (Int J Eat Disord 2013)
    4. Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer. (PubMed id 20932654)1 Kerns S.L....Rosenstein B.S. (Int. J. Radiat. Oncol. Biol. Phys. 2010)
    5. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells. (PubMed id 12590134)1 Fukuda M. (J. Biol. Chem. 2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Rab27a negatively regulates CFTR chloride channel function in colonic epithelia: involvement of the effector proteins in the regulatory mechanism. (PubMed id 16762324)9 Saxena S.K. and Kaur S. (Biochem. Biophys. Res. Commun. 2006)
    10. Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. (PubMed id 18266782)9 Holt O.... Griffiths G.M. (Traffic 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 94122 HGNC: 15589 AceView: SYTL5 Ensembl:ENSG00000147041 euGenes: HUgn94122
    ECgene: SYTL5 H-InvDB: SYTL5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYTL5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYTL5 gene:
    Search GeneIP for patents involving SYTL5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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