Aliases for SYTL5 Gene
External Ids for SYTL5 Gene
Previous GeneCards Identifiers for SYTL5 Gene
The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for SYTL5 Gene
SYTL5 (Synaptotagmin Like 5) is a Protein Coding gene. Among its related pathways are Deregulation of Rab and Rab Effector Genes in Bladder Cancer and wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF). GO annotations related to this gene include calcium ion binding and syntaxin binding. An important paralog of this gene is SYTL4.
UniProtKB/Swiss-Prot for SYTL5 Gene
May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.