SYTL1 Gene
protein-coding GIFtS: 51
GCID: GC01P027668
|
|
synaptotagmin-like 1
| |
Aliases for SYTL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Synaptotagmin-Like 11 2 | | NADPH Oxidase-Related, C2 Domain-Containing Protein2 | | SLP11 2 3 5 | | Synaptotagmin-Like Protein 12 | | JFC11 2 5 | | Exophilin-73 | | Exophilin-73 | | Protein JFC13 | | FLJ149961 | | |
Export aliases for SYTL1 gene to outside databasesPrevious GC identifers: GC01P027274 GC01P027352 GC01P027541 GC01P025924 |
Summaries for SYTL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SYTL1_HUMAN, Q8IYJ3Function: May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Actsas a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity) Gene Wiki entry for SYTL1
|
Genomic Views for SYTL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SYTL1 gene promoter: USF1 AML1a Olf-1 POU3F2 YY1 USF-1 IRF-7A ARP-1 NF-kappaB1 Other transcription factors
Search SABiosciences Chromatin IP Primers for SYTL1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYTL1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p35.3SYTL1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P027668: view genomic region
(about GC identifiers)
Start:
|
27,668,483 bp from pter |
End:
|
27,680,423 bp from pter |
Size:
|
11,941 bases |
Orientation:
|
plus strand |
|
Proteins for SYTL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SYTL1_HUMAN, Q8IYJ3 (See
protein sequence)Recommended Name: Synaptotagmin-like protein 1 Size: 562 amino acids; 61857 Da
Subunit: Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity).Binds NCF2
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane proteintightly bound to the cytoplasmic side of cellular membranes
Sequence caution: Sequence=AAH15764.1; Type=Erroneous initiation;
Secondary accessions: Q5SSC9 Q96BB6 Q96GU6 Q96S89 Q96SI0Alternative splicing: 2 isoforms: Q8IYJ3-1 Q8IYJ3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SYTL1: NX_Q8IYJ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYJ3 SYTL1 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (2 alternative transcripts):
NP_001180237.1 NP_116261.1 ENSEMBL proteins: ENSP00000316464 ENSP00000433671 ENSP00000420110 ENSP00000432815 ENSP00000417187 ENSP00000420349 ENSP00000440704 Human Recombinant Protein Products for SYTL1:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SYTL1 for ontologies About GeneDecksing
SYTL1 Antibody Products: Assay Products for SYTL1: |
Protein
Domains / Families for SYTL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SYTL1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IYJ3ProtoNet protein and cluster: Q8IYJ3 2 Blocks protein families: IPB000008 C2 domain IPB001565 Synaptotagmin signature
UniProtKB/Swiss-Prot: SYTL1_HUMAN, Q8IYJ3Similarity: Contains 2 C2 domainsSimilarity: Contains 1 RabBD (Rab-binding) domain |
Function for SYTL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SYTL1_HUMAN, Q8IYJ3Function: May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Actsas a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity) Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SYTL1 for ontologies About GeneDecksing
Phenotypes: 10 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sytl1):
SYTL1 for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Sytl1tm1Mitf for SYTL1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SYTL1 (NM_032872) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SYTL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYTL1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYTL1 |
|
Pathways & Interactions for SYTL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | |
1 BioSystems Pathway for SYTL1 
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SYTL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
 5/7 Interacting proteins for SYTL1 (Q8IYJ33 ENSP000003164644) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SYTL1 for ontologies About GeneDecksing
|
Drugs & Compounds for SYTL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SYTL1
1 HMDB Compound for SYTL1 About this table Search CenterWatch for drugs/clinical trials and news about SYTL1 
|
Transcripts for SYTL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SYTL1 gene (2 alternative transcripts): NM_001193308.1 NM_032872.2 Unigene Cluster for SYTL1: Synaptotagmin-like 1 Hs.469175 [show with all ESTs]Unigene Representative Sequence: AK0741549 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000318074(uc001bnv.2) ENST00000483926(uc001bnw.2) ENST00000473280 ENST00000494895(uc001bnx.2) ENST00000490170 ENST00000496001 ENST00000485269 ENST00000475199 ENST00000543823(uc009vsv.2)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SYTL1 (NM_032872) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SYTL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYTL1  |
Additional cDNA sequence: AK027902.1 AK074154.1 AK096437.1 AK097172.1 AK126120.1 AK293038.1 AY037157.1 BC009224.2 BC015764.1 BC035725.1 11 DOTS entries: DT.310113 DT.100644757 DT.92426536 DT.97859499 DT.86840989 DT.91922055 DT.95257063 DT.95253533 DT.121430217 DT.121430238 DT.95228143 24/192 AceView cDNA sequences (see all 192): BM922835 BF061800 AK027902 AI973222 BM920625 BM129773 AK097172 BQ953055 BI908237 NM_032872 CR612838 BM742237 BM805142 AK096437 BM781724 BM781732 BP334236 CR604153 AI656111 BQ706222 BF663585 BM141958 AI972204 CR626119 GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for SYTL1 (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | |
| SP1: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21a | · | 21b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SYTL1
|
Expression for SYTL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SYTL1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGGCCCTGGC
 About this image See SYTL1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SYTL1
SOURCE GeneReport for Unigene cluster: Hs.469175
UniProtKB/Swiss-Prot: SYTL1_HUMAN, Q8IYJ3Tissue specificity: Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum,occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL) SABiosciences Custom PCR Arrays for SYTL1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYTL1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SYTL1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYTL1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYTL1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYTL1 |
Orthologs for SYTL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SYTL1 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SYTL11 |
synaptotagmin-like 1 |
63.9(n) 57.61(a) |
  |
771987 NM_001080889.1 NP_001074358.1 |
lizard (Anolis carolinensis) |
Reptilia |
SYTL16 |
-- |
58(a) |
1 ↔ 1 |
GL343464.1(249268-255346) |
African clawed frog (Xenopus laevis) |
Amphibia |
BJ075803.12 |
-- |
72.26(n) |
  |
BJ075803.1 |
zebrafish (Danio rerio) |
Actinopterygii |
si:dkey-228a15.31 |
si:dkey-228a15.3 |
53.26(n) 47.85(a) |
  |
777759 XM_003200634.1 XP_003200682.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
btsz6 |
bitesize |
4(a) |
1 → many |
3R(10629814-10679626) |
worm (Caenorhabditis elegans) |
Secernentea |
snt-66 |
SyNapTotagmin family member (snt-6) |
18(a) |
possible ortholog |
II(745469-750171) |
ENSEMBL Gene Tree for SYTL1 (if available) TreeFam Gene Tree for SYTL1 (if available)  |
Paralogs for SYTL1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SYTL1 gene
- SYTL42 DOC2B2 SYTL52 DOC2A2 SYTL32 RPH3A2 SYTL22
9 SIMAP similar genes for SYTL1 using alignment to 7 protein entries: SYTL1_HUMAN (see all proteins):FLJ00227 CHR11SYT SYTL2 SYTL5 SYTL3 SYTL4 SYT1 SYT2 SYT5
SYTL1 for paralogs About GeneDecksing
|
Genomic Variants for SYTL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SYTL1 (27668483 - 27680423 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for SYTL1 1 CNV: 48306  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for SYTL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SYTL1 for disorders About GeneDecksing
OMIM gene information: 608042
OMIM disorders: --
4 diseases for SYTL1: About MalaCardscrohn's disease prostate carcinoma prostatitis carcinoma Export disorders for SYTL1 gene to outside databases
|
Publications for SYTL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SYTL1 gene, integrated from 9 sources (see all 21): (articles sorted by number of sources associating them with SYTL1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. (PubMed id 18266782)1, 2 Holt O....Griffiths G.M. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- JFC1 is transcriptionally activated by nuclear factor-kappaB and up-regulated by tumour necrosis factor alpha in prostate carcinoma cells. (PubMed id 12137562)1, 3 Catz S.D....Johnson J.L. (2002)
- JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. (PubMed id 11278853)1, 2 McAdara Berkowitz J.K....Babior B.M. (2001)
- Synaptotagmin-like protein 1 interacts with the GTPas e-activating protein Rap1GAP2 and regulates dense granule secretion in platelet s. (PubMed id 19528539)1, 9 NeumA1ller O....Smolenski A.P. (2009)
- The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase. (PubMed id 16004602)1, 9 Johnson J.L....Catz S.D. (2005)
- Vesicular trafficking through cortical actin during ex ocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activ ating protein Gem-interacting protein. (PubMed id 22438581)1 Johnson J.L....Catz S.D. (2012)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease. (PubMed id 17200145)1 Schmid M....Wehkamp J. (2007)
|
External Searches for SYTL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SYTL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SYTL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SYTL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SYTL1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SYTL1 gene: Search GeneIP for patents involving SYTL1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SYTL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SYTL1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYTL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYTL1 | | OriGene Protein Over-expression Lysate for SYTL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SYTL1 | | OriGene 3'-UTR Clone for SYTL1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYTL1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SYTL1 | | OriGene Custom Protein Services for SYTL1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYTL1 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYTL1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYTL1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYTL1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYTL1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYTL1 |
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| | | Search Tocris compounds for SYTL1 |
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 | | SYTL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYTL1 |
|  |  |  |  | | | Search ThermoFisher Antibodies for SYTL1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYTL1 |
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