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SYT9 Gene

protein-coding   GIFtS: 53
GCID: GC11P007273

Synaptotagmin IX

  Search for SYT9
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synaptotagmin IX1 2 3
synaptotagmin-92
sytIX2
SytIX3

External Ids:    HGNC: 192651   Entrez Gene: 1434252   Ensembl: ENSG000001707437   OMIM: 6135285   UniProtKB: Q86SS63   

Export aliases for SYT9 gene to outside databases

Previous GC identifers: GC00U906273 GC11P007229 GC11P006931


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SYT9 Gene:
SYT9 (synaptotagmin IX) is a protein-coding gene. GO annotations related to this gene include transporter activity and identical protein binding. An important paralog of this gene is SYT15.

UniProtKB/Swiss-Prot: SYT9_HUMAN, Q86SS6
Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

Gene Wiki entry for SYT9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYT9 gene promoter:
         TBP   STAT1   STAT4   p300   MyoD   STAT1alpha   CREB   TFIID   deltaCREB   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYT9 promoter sequence
   Search Chromatin IP Primers for SYT9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYT9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

SYT9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT9 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P007273:  view genomic region     (about GC identifiers)

Start:
7,260,009 bp from pter      End:
7,490,276 bp from pter
Size:
230,268 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SYT9_HUMAN, Q86SS6 (See protein sequence)
Recommended Name: Synaptotagmin-9  
Size: 491 amino acids; 56188 Da
Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains (By similarity)

Explore the universe of human proteins at neXtProt for SYT9: NX_Q86SS6

Explore proteomics data for SYT9 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SYT9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_783860.1  
    ENSEMBL proteins: 
     ENSP00000432141   ENSP00000324419   ENSP00000434558   ENSP00000379944  

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    Search eBioscience for ELISAs for SYT9 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SYT: Synaptotagmins

    3 InterPro protein domains:
     IPR001565 Synaptotagmin
     IPR000008 C2_dom
     IPR028691 SYT9

    Graphical View of Domain Structure for InterPro Entry Q86SS6

    ProtoNet protein and cluster: Q86SS6

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: SYT9_HUMAN, Q86SS6
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    Find genes that share domains with SYT9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT9_HUMAN, Q86SS6
    Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
    binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005515protein binding ----
    GO:0042802identical protein binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with SYT9           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYT9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SYT9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYT9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYT9

    miRNA
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    miRTarBase miRNAs that target SYT9:
    hsa-mir-196a-5p (MIRT026062)

    Block miRNA regulation of human, mouse, rat SYT9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYT9 (see all 48):
    hsa-miR-607 hsa-miR-330-5p hsa-miR-29a hsa-miR-488 hsa-miR-650 hsa-miR-449a hsa-miR-9 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidSYT9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SYT9

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    GenScript: all cDNA clones in your preferred vector: SYT9 (NM_175733)
    Sino Biological Human cDNA Clone for SYT9
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SYT9_HUMAN, Q86SS6: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane
    protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008021synaptic vesicle ----
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0030054cell junction IEA--
    GO:0030141secretory granule ----

    Find genes that share ontologies with SYT9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYT9
    Interactions:

        Search GeneGlobe Interaction Network for SYT9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for SYT9 (Q86SS63 ENSP000003244194) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000232575P074373, ENSP000004100714I2D: score=1 STRING: ENSP00000410071
    ENSG00000183311P074373I2D: score=1 
    ENSG00000224156P074373I2D: score=1 
    ENSG00000227739P074373I2D: score=1 
    ENSG00000229684P074373I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017158regulation of calcium ion-dependent exocytosis ----
    GO:0045956positive regulation of calcium ion-dependent exocytosis IEA--
    GO:0050796regulation of insulin secretion IEA--

    Find genes that share ontologies with SYT9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYT9

    1 HMDB Compound for SYT9    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 Novoseek inferred chemical compound relationship for SYT9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 5.82 1 14983047 (1)



    Find genes that share compounds with SYT9           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYT9 gene: 
    NM_175733.3  

    Unigene Cluster for SYT9:

    Synaptotagmin IX
    Hs.177193  [show with all ESTs]
    Unigene Representative Sequence: BC046367
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000524820(uc001mfd.3) ENST00000318881(uc001mfe.3 uc009yfi.3)
    ENST00000532592 ENST00000396716
    miRNA
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    Block miRNA regulation of human, mouse, rat SYT9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYT9 (see all 48):
    hsa-miR-607 hsa-miR-330-5p hsa-miR-29a hsa-miR-488 hsa-miR-650 hsa-miR-449a hsa-miR-9 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidSYT9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SYT9
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    OriGene ORF clones in mouse, rat for SYT9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYT9 (NM_175733)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT9
    Primer
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    OriGene qPCR primer pairs and template standards for SYT9
    OriGene qSTAR qPCR primer pairs in human, mouse for SYT9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SYT9
      QuantiTect SYBR Green Assays in human, mouse, rat SYT9
      QuantiFast Probe-based Assays in human, mouse, rat SYT9

    Additional mRNA sequence: 

    AK055003.1 AK055929.1 AK127795.1 AK315013.1 AL137512.1 BC046367.1 

    3 DOTS entries:

    DT.434225  DT.101955565  DT.99939354 

    23 AceView cDNA sequences:

    AK055929 BC029605 BX108745 BM928247 BM561215 Z39450 NM_175733 BE047105 
    BI560415 AK127795 BC046367 AI955186 BF197562 CD250937 AL137512 AK055003 
    H17258 BM553771 BQ720470 Z43379 H17257 H08332 H08235 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SYT9    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                                                                  
    SP2:                          -                       -     -         
    SP3:                    -     -                       -     -         


    ECgene alternative splicing isoforms for SYT9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYT9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAGGCAGGT
    SYT9 Expression
    About this image


    SYT9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    SYT9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYT9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.177193
        Custom PCR Arrays for SYT9
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    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SYT9 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt91 , 5 synaptotagmin IX1, 5 90.77(n)1
    97.56(a)1
      7 (56.33 cM)5
    605101  NM_021889.41  NP_068689.21 
     1073707285 
    chicken
    (Gallus gallus)
    Aves SYT91 synaptotagmin IX 81.09(n)
    89.07(a)
      423026  XM_003641313.2  XP_003641361.2 
    lizard
    (Anolis carolinensis)
    Reptilia SYT96
    synaptotagmin IX
    78(a)
    1 ↔ 1
    GL343237.1(2045893-2146467)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia syt91 synaptotagmin IX 75.72(n)
    82.1(a)
      100497543  XM_002938037.2  XP_002938083.2 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb8442 sbcb844 72.16(n)   378858  BI475373.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syt16
    Synaptotagmin 1
    33(a)
    1 → many
    2L(2779267-2799979)
    worm
    (Caenorhabditis elegans)
    Secernentea snt-36
    snt-16
    (see all 3)
    Protein SNT-3
    Protein SNT-1, isoform b (snt-1) mRNA, complete cd...
    (see all 3)
    44(a)
    34(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    V(1358186-1361318) WBGene00004923
    II(6810963-6816454) WBGene00004921


    ENSEMBL Gene Tree for SYT9 (if available)
    TreeFam Gene Tree for SYT9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYT9 gene
    SYT152  SYT42  SYT52  SYT82  SYT102  SYT32  SYT62  SYT172  
    SYT112  SYT122  SYT22  SYT72  SYT12  
    15 SIMAP similar genes for SYT9 using alignment to 5 protein entries:     SYT9_HUMAN (see all proteins):
    SYT3    SYT10    SYT2    SYT1    SYT6    PRKCG
    SYT7    SYTL2    SYT4    SYT5    CHR11SYT    SYT11
    SYT15    SYT17    SYT12

    Find genes that share paralogs with SYT9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYT9 (see all 4022)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0363904
    A colorectal cancer sample4--see VAR_0363902 D N mis40--------
    rs678100751,2
    C--6950429(+) CACAG-/AC    
       
    /ACAC
    ACACA
    1 -- int11NA 2
    rs105006871,2
    C,F,A,H--7271224(+) GTTCTC/GATTGC 1 -- us2k199Minor allele frequency- G:0.04NS NA EA PA EU CA WA CSA 5123
    rs118203261,2
    C,F,H--7271315(+) TTCCAA/GTGATG 1 -- us2k122Minor allele frequency- G:0.10NA NS EA WA CSA 2198
    rs766070231,2
    F--7271323(+) ATGATT/CGCCAG 1 -- us2k11Minor allele frequency- C:0.01EA 120
    rs107697721,2
    C,H--7271334(+) TCTTCC/ACTCTC 1 -- us2k111Minor allele frequency- A:0.00NA WA CSA 138
    rs118208351,2
    C,F,H--7271381(+) GGGTGT/CGAGCA 1 -- us2k19Minor allele frequency- C:0.04NS EA NA CSA WA 644
    rs1443961761,2
    --7271403(+) GGTAAC/TGTTTT 1 -- us2k10--------
    rs1921259791,2
    --7271410(+) TTTTGA/TAACGT 1 -- us2k10--------
    rs1478126501,2
    C--7271492(+) TTTGGA/GTGTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SYT9 (7260009 - 7490276 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SYT9 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2288433CNV Deletion18987734
    esv2663215CNV Deletion23128226
    esv2448178CNV Deletion19546169
    esv2744079CNV Deletion23290073
    esv268316CNV Insertion20981092
    esv274595CNV Insertion20981092
    esv269864CNV Insertion20981092
    esv2450231CNV Insertion19546169
    nsv896976CNV Loss21882294
    dgv57n21CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYT9
    DNA2.0 Custom Variant and Variant Library Synthesis for SYT9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613528    OMIM disorders: --


    Find genes that share disorders with SYT9           About GenesLikeMe

    Genetic Association Database (GAD): SYT9
    Human Genome Epidemiology (HuGE) Navigator: SYT9 (1 document)

    Export disorders for SYT9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYT9 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with SYT9)
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    world of online information

    1. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1, 4 Demirkan A....Schmitz G. (PLoS Genet. 2012)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Genomic analysis of synaptotagmin genes. (PubMed id 11543631)1, 3 Craxton M.A. (Genomics 2001)
    5. Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells. (PubMed id 11751925)1, 9 Fukuda M....Mikoshiba K. (J. Biol. Chem. 2002)
    6. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    7. Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis. (PubMed id 21220648)2 Daoud H....Rouleau G.A. (Arch. Neurol. 2011)
    8. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    9. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PubMed id 17903295)4 Lunetta K.L....Murabito J.M. (BMC Med. Genet. 2007)
    10. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 143425 HGNC: 19265 AceView: SYT9 Ensembl:ENSG00000170743 euGenes: HUgn143425
    ECgene: SYT9 H-InvDB: SYT9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYT9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYT9 gene:
    Search GeneIP for patents involving SYT9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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