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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SYT8 Gene

protein-coding GIFtS: 48
GCID: GC11P001849

synaptotagmin VIII

Explore 2 diseases affiliated with
SYT8 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Synaptotagmin VIII¹ ² ³
DKFZp434K0322¹
Synaptotagmin 8²
Synaptotagmin-8¹
SytVIII³
SytVIII³

External Ids:	HGNC: 19264¹	Entrez Gene: 90019²	Ensembl: ENSG00000149043⁷	OMIM: 607719⁵	UniProtKB: Q8NBV8³

Export aliases for SYT8 gene to outside databases

Previous GC identifers: GC11M001967 GC11P001813 GC11P001818 GC11P001820 GC11P001811 GC11P001646

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT8:

Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a cytoplasmic

region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while others have a

more general function in endocytosis. For further information on synaptotagmins, see MIM 185605.(supplied by OMIM, May

2003)

UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8

Function: Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.

Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in

insulin secreted cells (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SYT8 gene promoter:
COUP-TF1 COUP Lmo2 HNF-4alpha2 AP-4 Tal-1beta Roaz HNF-4alpha1 E47 COUP-TF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SYT8 promoter sequence

Search SABiosciences Chromatin IP Primers for SYT8

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5

SYT8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT8 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P001849: view genomic region (about GC identifiers)

Start:	1,848,709 bp from pter	End:	1,858,751 bp from pter
Size:	10,043 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8 (See protein sequence)

Recommended Name: Synaptotagmin-8

Size: 401 amino acids; 44138 Da

Subunit: Homodimer or homooligomer. Homodimerization and homooligomerization do not depend on Ca(2+). Interacts with

SYNCRIP isoform 2 C-terminus. Binds inositol 1,3,4,5-tetrakisphosphate (IP4). Binds to AP2 in a Ca(2+)-independent

manner. Interacts with STX1A, STX1B and STX2; the interaction is Ca(2+)-dependent (By similarity)

Subcellular location: Cell membrane; Single-pass type III membrane protein (By similarity). Cytoplasmic vesicle,

secretory vesicle, acrosome (By similarity)

Sequence caution: Sequence=AAQ57209.1; Type=Miscellaneous discrepancy; Note=May be due to an intron retention;

Sequence=CAB70885.2; Type=Miscellaneous discrepancy; Note=The sequence differs from that shown because it is a

pre-mRNA;

Secondary accessions: A6NFJ4 Q9NSV9

Alternative splicing: 2 isoforms: Q8NBV8-4 Q8NBV8-1 (Variant in position: 143:R->Q (in dbSNP:rs907608). Variant in position: 152:T->M (in dbSNP:rs907609))

Explore the universe of human proteins at neXtProt for SYT8: NX_Q8NBV8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NBV8

SYT8 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_612634.3

ENSEMBL proteins:

ENSP00000392469 ENSP00000387678 ENSP00000371394 ENSP00000371406 ENSP00000343691

ENSP00000405850 ENSP00000443325 ENSP00000414626

Human Recombinant Protein Products for SYT8:

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	Uscn Proteins for SYT8

Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001669	acrosomal vesicle	IEA	--
GO:0005737	cytoplasm	--	--
GO:0005886	plasma membrane	IEA	--
GO:0008021	synaptic vesicle	IEA	--
GO:0016020	membrane	--	--

SYT8 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for SYT8

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SYT8 for domains About GeneDecksing

4 InterPro domains/families:

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR001565 Synaptotagmin

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry Q8NBV8

ProtoNet protein and cluster: Q8NBV8

UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8

Domain: The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding (By similarity)

Domain: The second C2 domain/C2B is responsible for SYNCRIP and inositol 1,3,4,5-tetrakisphosphate (IP4)-binding (By

similarity)

Similarity: Belongs to the synaptotagmin family

Similarity: Contains 2 C2 domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: SYT8_HUMAN, Q8NBV8

Function: Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.

Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in

insulin secreted cells (By similarity)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	IEA	--
GO:0048306	calcium-dependent protein binding	IEA	--

SYT8 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for SYT8:

Cell cycle / mitosis defect

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SYT8

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT8 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT8

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SYT8

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for SYT8 (Q8NBV8³ ENSP00000371394⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SYNCRIP	O60506³, ENSP00000358635⁴	I2D: score=2 STRING: ENSP00000358635

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007340	acrosome reaction	IEA	--

SYT8 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SYT8
Search CenterWatch for drugs/clinical trials and news about SYT8

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SYT8 gene:

NM_138567.3

Unigene Cluster for SYT8:

Synaptotagmin VIII

Hs.161031 [show with all ESTs]

Unigene Representative Sequence: BM907017

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000430303 ENST00000417052 ENST00000479276 ENST00000490707 ENST00000479089(uc001lud.2)

ENST00000381968(uc001lue.1) ENST00000464897 ENST00000475245 ENST00000381978

ENST00000341958 ENST00000424556 ENST00000482118(uc009ydb.2) ENST00000483280

ENST00000494431 ENST00000535046 ENST00000436964(uc010qxb.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT8
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SYT8
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT8 (see all 7) OriGene shRNA RFP: SYT8 OriGene siRNA: SYT8
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		Sirion Biotech Custom design and validation of potent shRNA sequences against SYT8

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		GenScript: all cDNA clones in your preferred vector: SYT8 (NM_138567)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT8
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT8

Additional cDNA sequence:

AK293395.1 BC038591.1 BC144657.1 BC144659.1 BC144660.1 BC144661.1

8 DOTS entries:

DT.97782207 DT.100752449 DT.40111962 DT.95283346 DT.100647944 DT.102822049 DT.100837849 DT.120723716

24/33 AceView cDNA sequences (see all 33):

CR619379 AK131292 NM_138567 AK075202 BX399734 BX282124 CR622425 CR601912

CR596759 BU608388 BF847943 BX378323 BX396540 BX396061 AL137708 AI814253

BX396060 AY353087 BV194019 BC038591 BM709614 BX365067 BU683204 CB321892

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SYT8 (see all 10) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	·	7d	^	8a	·	8b	^	9	^	10
SP1:																					-		-				-		-								-
SP2:											-		-								-		-				-		-
SP3:													-								-		-				-		-
SP4:													-								-		-
SP5:											-		-								-		-

ECgene alternative splicing isoforms for SYT8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SYT8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTCTGTCTC

About this image
See SYT8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYT8

SOURCE GeneReport for Unigene cluster: Hs.161031
SABiosciences Custom PCR Arrays for SYT8

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT8 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT8

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SYT8 gene from 4/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SYT8⁶	Uncharacterized protein	43(a)	1 ↔ 1	5(15210048-15213984)
lizard (Anolis carolinensis)	Reptilia	SYT8⁶	--	48(a)	1 ↔ 1	1(70735529-70748286)
zebrafish (Danio rerio)	Actinopterygii	syt8⁶	synaptotagmin VIII	43(a)	1 ↔ 1	25(32486949-32500006)
worm (Caenorhabditis elegans)	Secernentea	snt-6⁶ snt-2⁶	SyNapTotagmin family member (snt-2)	25(a) 25(a)	possible ortholog 1 ↔ 1	II(745469-750171) III(786694-793682)

ENSEMBL Gene Tree for SYT8 (if available)
TreeFam Gene Tree for SYT8 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SYT8 gene

SYT15² SYT4² SYT5² SYT9² SYT3² SYT10² SYT6² SYT17²

SYT11² SYT12² SYT7² SYT2² SYT1²

7 SIMAP similar genes for SYT8 using alignment to 8 protein entries: SYT8_HUMAN (see all proteins):

SYT2 SYT1 SYT5 SYT10 SYT11 SYT7

SYT6

SYT8 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs73410915^1,2	C,F	--	1853792(+)	`GGTCTC/TCAGGG`	1	--	us2k¹		3		WA CSA	122
rs192539775^1,2		--	1853844(+)	`GCGGAC/TGGCGC`	1	--	us2k¹		0	--	--	--	--
rs148851024^1,2		--	1854039(+)	`TGGCCC/TGGGAG`	1	--	us2k¹		0	--	--	--	--
rs7120282^1,2	C,A	--	1854058(+)	`GCCGGC/TCNNNN`	1	--	us2k¹		3		NA EA	242
rs7942044^1,2	C,F,A,H	--	1854087(+)	`CTCTCG/CCCGCC`	1	--	us2k¹		11		NA WA CSA EA	378
rs61867130^1,2		--	1854093(+)	`CCGCCC/GGGCCC`	1	--	us2k¹		3		NA EA	242
rs185326503^1,2		--	1854122(+)	`AGGAGG/TGGGGA`	1	--	us2k¹		0	--	--	--	--
rs11828241^1,2	C,F,H	--	1854128(+)	`GGGGAC/TGCCAG`	1	--	us2k¹		2		NA WA	122
rs61867131^1,2	C	--	1854356(+)	`TCTGGC/TCGGCA`	1	--	us2k¹		3		NA EA	242
rs11819918^1,2	C,F,H	--	1854391(+)	`GACCCA/GGCCCA`	1	--	us2k¹		6		NS EA NA WA	532

HapMap Linkage Disequilibrium report for SYT8 (1848709 - 1858751 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SYT8
4 CNVs: 29889 29892 29893 29890

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT8

DNA2.0 Custom Variant and Variant Library Synthesis for SYT8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SYT8 for disorders           About GeneDecksing

OMIM gene information: 607719    OMIM disorders: --

2 diseases for SYT8:    About MalaCards

pharyngitis neuronitis

Human Genome Epidemiology (HuGE) Navigator: SYT8 (4 documents)

Export disorders for SYT8 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SYT8 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with SYT8)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. (PubMed id 7791877)^{1, 3} Li C....Sudhof T.C. (1995)
Mapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription. (PubMed id 21336277)¹ Xu Z....Felsenfeld G. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)² Taylor T.D....Sakaki Y. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms. (PubMed id 10734137)¹ Mizutani A....Mikoshiba K. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 90019	HGNC: 19264	AceView: SYT8	Ensembl:ENSG00000149043	euGenes: HUgn90019
ECgene: SYT8	H-InvDB: SYT8

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SYT8	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SYT8 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SYT8 gene:
Search GeneIP for patents involving SYT8

GeneCards and IP:
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