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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYT8 Gene

protein-coding   GIFtS: 49
GCID: GC11P001849

Synaptotagmin VIII

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synaptotagmin VIII1 2 3
Synaptotagmin 82
synaptotagmin-82
sytVIII2
SytVIII3

External Ids:    HGNC: 192641   Entrez Gene: 900192   Ensembl: ENSG000001490437   OMIM: 6077195   UniProtKB: Q8NBV83   

Export aliases for SYT8 gene to outside databases

Previous GC identifers: GC11M001967 GC11P001813 GC11P001818 GC11P001820 GC11P001811 GC11P001646


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT8 Gene:
Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a
cytoplasmic region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while
others have a more general function in endocytosis. For further information on synaptotagmins, see MIM
185605.(supplied by OMIM, May 2003)

GeneCards Summary for SYT8 Gene: 
SYT8 (synaptotagmin VIII) is a protein-coding gene. Diseases associated with SYT8 include neuronitis. GO annotations related to this gene include calcium-dependent protein binding and transporter activity. An important paralog of this gene is DOC2B.

UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8
Function: Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal
tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of
exocytosis in insulin secreted cells (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYT8 gene promoter:
         COUP-TF1   COUP   Lmo2   HNF-4alpha2   AP-4   Tal-1beta   Roaz   HNF-4alpha1   E47   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SYT8 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYT8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

SYT8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT8 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P001849:  view genomic region     (about GC identifiers)

Start:
1,848,709 bp from pter      End:
1,858,751 bp from pter
Size:
10,043 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8 (See protein sequence)
Recommended Name: Synaptotagmin-8  
Size: 401 amino acids; 44138 Da
Subunit: Homodimer or homooligomer. Homodimerization and homooligomerization do not depend on Ca(2+). Interacts
with SYNCRIP isoform 2 C-terminus. Binds inositol 1,3,4,5-tetrakisphosphate (IP4). Binds to AP2 in a
Ca(2+)-independent manner. Interacts with STX1A, STX1B and STX2; the interaction is Ca(2+)-dependent (By
similarity)
Subcellular location: Cell membrane; Single-pass type III membrane protein (By similarity). Cytoplasmic vesicle,
secretory vesicle, acrosome (By similarity)
Sequence caution: Sequence=AAQ57209.1; Type=Miscellaneous discrepancy; Note=May be due to an intron retention;
Sequence=CAB70885.2; Type=Miscellaneous discrepancy; Note=The sequence differs from that shown because it is a
pre-mRNA;
Secondary accessions: A6NFJ4 Q9NSV9
Alternative splicing: 2 isoforms:  Q8NBV8-4   Q8NBV8-1   (Variant in position: 143:R->Q (in dbSNP:rs907608). Variant in position: 152:T->M (in dbSNP:rs907609))

Explore the universe of human proteins at neXtProt for SYT8: NX_Q8NBV8

Explore proteomics data for SYT8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NBV8

  • SYT8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYT8 Protein Expression
    REFSEQ proteins: NP_612634.3  
    ENSEMBL proteins: 
     ENSP00000392469   ENSP00000387678   ENSP00000371394   ENSP00000371406   ENSP00000343691  
     ENSP00000405850   ENSP00000443325   ENSP00000414626  

    Human Recombinant Protein Products for SYT8: 
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    Novus Biologicals SYT8 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SYT8 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--
    GO:0005737cytoplasm ----
    GO:0005886plasma membrane IEA--
    GO:0008021synaptic vesicle IEA--
    GO:0016020membrane ----

    SYT8 for ontologies           About GeneDecksing



    SYT8 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SYT: Synaptotagmins

    4 InterPro protein domains:
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR001565 Synaptotagmin
     IPR018029 C2_membr_targeting
     IPR000008 C2_Ca-dep

    Graphical View of Domain Structure for InterPro Entry Q8NBV8

    ProtoNet protein and cluster: Q8NBV8

    UniProtKB/Swiss-Prot: SYT8_HUMAN, Q8NBV8
    Domain: The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding (By similarity)
    Domain: The second C2 domain/C2B is responsible for SYNCRIP and inositol 1,3,4,5-tetrakisphosphate (IP4)-binding
    (By similarity)
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    SYT8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT8_HUMAN, Q8NBV8
    Function: Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal
    tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of
    exocytosis in insulin secreted cells (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005515protein binding ----
    GO:0048306calcium-dependent protein binding IEA--
         
    SYT8 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SYT8:
     Cell cycle / mitosis defect 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYT8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SYT8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYT8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYT8 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYT8

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SYT8 (Q8NBV83 ENSP000003713944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SYNCRIPO605063, ENSP000003586354I2D: score=2 STRING: ENSP00000358635
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007340acrosome reaction IEA--

    SYT8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYT8

    Search CenterWatch for drugs/clinical trials and news about SYT8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYT8 gene: 
    NM_138567.3  

    Unigene Cluster for SYT8:

    Synaptotagmin VIII
    Hs.161031  [show with all ESTs]
    Unigene Representative Sequence: BM907017
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000430303 ENST00000417052 ENST00000479276 ENST00000490707 ENST00000479089(uc001lud.2)
    ENST00000381968(uc001lue.1) ENST00000464897 ENST00000475245 ENST00000381978
    ENST00000341958 ENST00000424556 ENST00000482118(uc009ydb.2) ENST00000483280
    ENST00000494431 ENST00000535046 ENST00000436964(uc010qxb.1)
    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SYT8
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT8
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                         Customized lentivirus expression plasmids for stable overexpression of SYT8 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT8

    Additional mRNA sequence: 

    AK293395.1 BC038591.1 BC144657.1 BC144659.1 BC144660.1 BC144661.1 

    8 DOTS entries:

    DT.97782207  DT.100752449  DT.40111962  DT.95283346  DT.100647944  DT.102822049  DT.100837849  DT.120723716 

    24/33 AceView cDNA sequences (see all 33):

    BX399734 AK075202 AK131292 NM_138567 CR596759 CR601912 CR619379 CR622425 
    BX282124 BX399733 BV194019 AL137708 AY353087 BU683204 BX396540 BX365068 
    AI814253 BM709614 CB321892 BX378323 BC038591 BU608388 BF847943 BX396060 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SYT8 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9 ^ 10
    SP1:                                                              -     -           -     -                       -                           
    SP2:                                -     -                       -     -           -     -                                                   
    SP3:                                      -                       -     -           -     -                                                   
    SP4:                                      -                       -     -                                                                     
    SP5:                                -     -                       -     -                                                                     


    ECgene alternative splicing isoforms for SYT8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYT8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCTGTCTC
    SYT8 Expression
    About this image


    See SYT8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYT8

    SOURCE GeneReport for Unigene cluster: Hs.161031
        SABiosciences Custom PCR Arrays for SYT8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SYT8 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt81 , 5 synaptotagmin VIII1, 5 77.95(n)1
    76.04(a)1
      7 (87.93 cM)5
    559251  NM_018802.41  NP_061272.21 
     1424348505 
    chicken
    (Gallus gallus)
    Aves SYT86
    Uncharacterized protein
    46(a)
    1 ↔ 1
    5(13487247-13490212)
    lizard
    (Anolis carolinensis)
    Reptilia SYT86
    synaptotagmin VIII
    47(a)
    1 ↔ 1
    1(70734689-70762046)
    zebrafish
    (Danio rerio)
    Actinopterygii syt86
    synaptotagmin VIII
    45(a)
    1 ↔ 1
    25(32486949-32500006)
    fruit fly
    (Drosophila melanogaster)
    Insecta Syt16
    Synaptotagmin 1
    29(a)
    1 → many
    2L(2779267-2799979)


    ENSEMBL Gene Tree for SYT8 (if available)
    TreeFam Gene Tree for SYT8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYT8 gene
    DOC2B2  SYT42  SYT52  SYT92  SYT102  SYT32  SYT62  SYT172  
    SYT112  SYT122  SYT22  DOC2A2  SYT72  RPH3A2  SYT12  
    7 SIMAP similar genes for SYT8 using alignment to 8 protein entries:     SYT8_HUMAN (see all proteins):
    SYT2    SYT1    SYT5    SYT10    SYT11    SYT7
    SYT6

    SYT8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/198 SNPs in SYT8 are shown (see all 198)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs734109151,2
    C,F--1853792(+) GGTCTC/TCAGGG 1 -- us2k13Minor allele frequency- T:0.43WA CSA 122
    rs1925397751,2
    --1853844(+) GCGGAC/TGGCGC 1 -- us2k10--------
    rs1488510241,2
    C--1854039(+) TGGCCC/TGGGAG 1 -- us2k10--------
    rs71202821,2
    C,A--1854058(+) GCCGGC/TCGCGG 1 -- us2k13Minor allele frequency- T:0.12NA EA 242
    rs79420441,2
    C,F,A,H--1854087(+) CTCTCG/CCCGCC 1 -- us2k111Minor allele frequency- C:0.35NA WA CSA EA 378
    rs618671301,2
    C--1854093(+) CCGCCC/GGGCCC 1 -- us2k13Minor allele frequency- G:0.12NA EA 242
    rs1853265031,2
    --1854122(+) AGGAGG/TGGGGA 1 -- us2k10--------
    rs118282411,2
    C,F,H--1854128(+) GGGGAC/TGCCAG 1 -- us2k12Minor allele frequency- T:0.05NA WA 122
    rs618671311,2
    C--1854356(+) TCTGGC/TCGGCA 1 -- us2k13Minor allele frequency- T:0.11NA EA 242
    rs118199181,2
    C,F,H--1854391(+) GACCCA/GGCCCA 1 -- us2k16Minor allele frequency- G:0.01NS EA NA WA 532

    HapMap Linkage Disequilibrium report for SYT8 (1848709 - 1858751 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for SYT8 (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv984n71CNV Loss21882294
    dgv986n71CNV Loss21882294
    nsv896746CNV Loss21882294
    nsv522320CNV Loss19592680
    nsv896731CNV Loss21882294
    dgv985n71CNV Loss21882294
    nsv469926CNV Loss18288195
    nsv896737CNV Loss21882294
    esv29980CNV Loss17803354
    nsv896739CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607719    OMIM disorders: --

    2 diseases for SYT8:    About MalaCards
    neuronitis    


    SYT8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SYT8
    Human Genome Epidemiology (HuGE) Navigator: SYT8 (4 documents)

    Export disorders for SYT8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYT8 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SYT8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. (PubMed id 7791877)1, 3 Li C....Sudhof T.C. (1995)
    5. Mapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription. (PubMed id 21336277)1 Xu Z....Felsenfeld G. (2011)
    6. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms. (PubMed id 10734137)1 Mizutani A....Mikoshiba K. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90019 HGNC: 19264 AceView: SYT8 Ensembl:ENSG00000149043 euGenes: HUgn90019
    ECgene: SYT8 H-InvDB: SYT8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYT8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYT8 gene:
    Search GeneIP for patents involving SYT8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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