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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYT6 Gene

protein-coding   GIFtS: 53
GCID: GC01M114631

Synaptotagmin VI

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synaptotagmin VI1 2 3
synaptotagmin-62
sytVI2
SytVI3

External Ids:    HGNC: 186381   Entrez Gene: 1482812   Ensembl: ENSG000001342077   OMIM: 6077185   UniProtKB: Q5T7P83   

Export aliases for SYT6 gene to outside databases

Previous GC identifers: GC01M115046 GC01M113515 GC01M113733 GC01M113931 GC01M113922 GC01M114346 GC01M114433 GC01M112489


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT6 Gene:
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain
structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are
involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component
of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been
found for this gene. (provided by RefSeq, Dec 2011)

GeneCards Summary for SYT6 Gene: 
SYT6 (synaptotagmin VI) is a protein-coding gene. Diseases associated with SYT6 include clear cell renal cell carcinoma, and renal cell carcinoma. GO annotations related to this gene include transporter activity and protein homodimerization activity. An important paralog of this gene is DOC2B.

UniProtKB/Swiss-Prot: SYT6_HUMAN, Q5T7P8
Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity)

Gene Wiki entry for SYT6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYT6 gene promoter:
         SRF   FOXF2   SRF (504 AA)   NRSF form 1   Lmo2   NRSF form 2   GATA-1   CREB   HEN1   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYT6 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYT6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.2   Ensembl cytogenetic band:  1p13.2   HGNC cytogenetic band: 1p13.1

SYT6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT6 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M114631:  view genomic region     (about GC identifiers)

Start:
114,631,914 bp from pter      End:
114,696,472 bp from pter
Size:
64,559 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYT6_HUMAN, Q5T7P8 (See protein sequence)
Recommended Name: Synaptotagmin-6  
Size: 510 amino acids; 57325 Da
Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains (By similarity)
Subunit: Homodimer (isoform 1). Isoform 1 forms heterodimers with SytIII, SytV and SytX. Interacts with STX1A,
STX1B and STX2; the interaction is Ca(2+)-dependent. Isoform 2 is not able to form homodimer and heterodimers (By
similarity)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane
protein (By similarity)
Subcellular location: Isoform 1: Membrane; Single-pass membrane protein (By similarity). Note=Localized
predominantly to endoplasmic reticulum (ER) and/or Golgi-like perinuclear compartment (By similarity)
Subcellular location: Isoform 2: Cytoplasm, cytosol (By similarity). Cell membrane; Peripheral membrane protein
(By similarity)
Secondary accessions: B1AMB8 B3KPK1
Alternative splicing: 2 isoforms:  Q5T7P8-1   Q5T7P8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYT6: NX_Q5T7P8

Explore proteomics data for SYT6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5T7P8

  • SYT6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYT6 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001257734.1  NP_995320.1  

    ENSEMBL proteins: 
     ENSP00000376974   ENSP00000358560  

    Human Recombinant Protein Products for SYT6: 
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    Cloud-Clone Corp. Proteins for SYT6 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol ISS--
    GO:0005886plasma membrane ISS--
    GO:0016021integral to membrane ISS--
    GO:0019898extrinsic to membrane ISS--
    GO:0030054cell junction IEA--

    SYT6 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SYT: Synaptotagmins

    5 InterPro protein domains:
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR001565 Synaptotagmin
     IPR018029 C2_membr_targeting
     IPR020477 C2_dom
     IPR000008 C2_Ca-dep

    Graphical View of Domain Structure for InterPro Entry Q5T7P8

    ProtoNet protein and cluster: Q5T7P8

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: SYT6_HUMAN, Q5T7P8
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    SYT6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT6_HUMAN, Q5T7P8
    Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
    binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
    May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity)

         Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005515protein binding ----
    GO:0005544NOT calcium-dependent phospholipid binding IDA7791877
    GO:0019905syntaxin binding IDA7791877
    GO:0030276clathrin binding IDA7791877
         
    SYT6 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SYT6:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Syt6):
     normal 

    SYT6 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Syt6tm1Sud for SYT6

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYT6 
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    hsa-miR-142-5p hsa-miR-607 hsa-miR-301a hsa-miR-192 hsa-miR-519a hsa-miR-3167 hsa-miR-186 hsa-miR-508-5p
    SwitchGear 3'UTR luciferase reporter plasmidSYT6 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYT6

    5/6 Interacting proteins for SYT6 (Q5T7P83) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NRXN1Q9ULB13I2D: score=1 
    PRKCBP057713I2D: score=1 
    STX1AQ166233I2D: score=1 
    STX1BP612663I2D: score=1 
    STX3Q132773I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007340acrosome reaction ----
    GO:0060478acrosomal vesicle exocytosis IMP11437455

    SYT6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYT6

    1 HMDB Compound for SYT6    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about SYT6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYT6 gene (3 alternative transcripts): 
    NM_001270805.1  NM_205848.3  NM_001253772.1  

    Unigene Cluster for SYT6:

    Synaptotagmin VI
    Hs.370963  [show with all ESTs]
    Unigene Representative Sequence: NM_001270805
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393296(uc021osa.1) ENST00000369547(uc001eeu.3 uc021orz.1 uc001eev.3)

    miRNA
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    8/60 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT6 (see all 60):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-301a hsa-miR-192 hsa-miR-519a hsa-miR-3167 hsa-miR-186 hsa-miR-508-5p
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    Additional mRNA sequence: 

    AK056448.1 AK096744.1 BC044948.1 

    5 DOTS entries:

    DT.100745611  DT.107939  DT.100725421  DT.107940  DT.100678014 

    24/34 AceView cDNA sequences (see all 34):

    NM_205848 F12220 BQ068182 BQ777980 BQ777677 CR594520 BC044948 BX093734 
    F09849 BX431128 AW149740 CA840960 AI863338 AK096744 AK056448 BV195298 
    AL535655 AV726171 CD651934 N54629 CF541077 CA841217 AI223268 N50928 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SYT6    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
    SP1:        -     -     -     -                                                         
    SP2:                          -                                                         
    SP3:                                                                    -               
    SP4:                    -                                                               
    SP5:                    -     -                                                         


    ECgene alternative splicing isoforms for SYT6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYT6 expression in normal human tissues (normalized intensities)      SYT6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAGTTCCC
    SYT6 Expression
    About this image


    SYT6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/38 selected tissues (see all 38) fully expand
     
     Brain (Nervous System)    fully expand to see all 26 entries
             Thalamus
             Substantia Nigra   
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus (Reproductive System)    fully expand to see all 5 entries
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; endothelial cells   

    See SYT6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYT6

    SOURCE GeneReport for Unigene cluster: Hs.370963
        SABiosciences Custom PCR Arrays for SYT6
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SYT6 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt61 , 5 synaptotagmin VI1, 5 90.35(n)1
    96.94(a)1
      3 (45.45 cM)5
    545241  NM_018800.31  NP_061270.21 
     1035752315 
    chicken
    (Gallus gallus)
    Aves SYT61 synaptotagmin VI 78.95(n)
    87.22(a)
      428270  XM_425830.3  XP_425830.3 
    lizard
    (Anolis carolinensis)
    Reptilia SYT66
    synaptotagmin VI
    86(a)
    1 ↔ 1
    4(129850149-129999934)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.188382 Xenopus laevis transcribed sequence with weak similarity more 89.22(n)    BG347110.1 
    zebrafish
    (Danio rerio)
    Actinopterygii syt6a1 synaptotagmin VIa 72.58(n)
    81.09(a)
      100149310  XM_001920428.1  XP_001920463.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R12A1.23   -- 40(a)
    (best of 2)
      V(1393195-1411388)   --


    ENSEMBL Gene Tree for SYT6 (if available)
    TreeFam Gene Tree for SYT6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYT6 gene
    DOC2B2  SYT42  SYT52  SYT92  SYT82  SYT102  SYT32  SYT172  
    SYT112  SYT122  SYT22  DOC2A2  SYT72  RPH3A2  SYT12  
    15 SIMAP similar genes for SYT6 using alignment to 4 protein entries:     SYT6_HUMAN (see all proteins):
    SYT10    SYT1    SYT2    SYT7    SYT9    SYT5
    SYT3    SYT4    DKFZp434D2429    SYT12    RPH3A    SYT11
    CHR11SYT    SYT8    SYT17

    SYT6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1642 SNPs in SYT6 are shown (see all 1642)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2005277001,2
    --114631476(+) TGTTC-/TTTTTT 2 -- ds50010--------
    rs26298161,2
    C,F,A--114631484(+) TTTTTA/TAAAAA 2 -- ds50017Minor allele frequency- T:0.41NA WA EA 366
    rs1399778231,2
    --114631673(+) ACAGCA/GGAGCC 2 -- ds50010--------
    rs778142861,2
    C--114631769(+) CAGAAA/CAAAAA 2 -- ds50010--------
    rs778998481,2
    C--114631780(+) ACAAAA/CAAGCC 2 -- ds50010--------
    rs782018561,2
    C,F--114631842(+) ATTGAG/AAAGAA 2 -- ds50011Minor allele frequency- A:0.11WA 118
    rs24321,2
    C,F,O,A,H--114631980(+) ACAAAT/CGAGTA 2 -- ut31 ese3106Minor allele frequency- C:0.32NS NA EA PA EU CA WA 6806
    rs1813876091,2
    --114631981(+) CAAACA/GAGTAA 2 -- ut310--------
    rs1841410521,2
    --114632027(+) ATTAAC/TGTCCT 2 -- ut310--------
    rs38110171,2
    H--114632070(-) TTTCCG/AGGCTG 2 -- ut31 ese35Minor allele frequency- A:0.00EA NS 1920

    HapMap Linkage Disequilibrium report for SYT6 (114631914 - 114696472 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SYT6:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv2476CNV Insertion18451855
    esv23869CNV Loss19812545
    nsv528503CNV Loss19592680
    nsv517962CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607718    OMIM disorders: --

    2 diseases for SYT6:    About MalaCards
    clear cell renal cell carcinoma    renal cell carcinoma


    SYT6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SYT6

    Export disorders for SYT6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYT6 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with SYT6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Genomic analysis of synaptotagmin genes. (PubMed id 11543631)1, 3 Craxton M.A. (2001)
    4. Synaptotagmin VI participates in the acrosome reaction of human spermatozoa. (PubMed id 11437455)1, 9 Michaut M....Mayorga L.S. (2001)
    5. Protein kinase C-mediated phosphorylation of the two polybasic regions of synaptotagmin VI regulates their function in acrosomal exocytosis. (PubMed id 16111671)1, 9 Roggero C.M....Mayorga L.S. (2005)
    6. Identification of inherited genetic variations influen cing prognosis in early-onset breast cancer. (PubMed id 23319801)1 Rafiq S....Eccles D. (2013)
    7. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. Calcineurin-mediated dephosphorylation of synaptotagm in VI is necessary for acrosomal exocytosis. (PubMed id 20551332)1 Castillo Bennett J....Mayorga L.S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 148281 HGNC: 18638 AceView: SYT6 Ensembl:ENSG00000134207 euGenes: HUgn148281
    ECgene: SYT6 H-InvDB: SYT6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYT6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYT6 gene:
    Search GeneIP for patents involving SYT6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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