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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYT5 Gene

protein-coding   GIFtS: 59
GCID: GC19M055684

Synaptotagmin V

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synaptotagmin V1 2 3
Synaptotagmin 51 2
synaptotagmin-52
sytV2
SytV3

External Ids:    HGNC: 115131   Entrez Gene: 68612   Ensembl: ENSG000001299907   OMIM: 6007825   UniProtKB: O004453   

Export aliases for SYT5 gene to outside databases

Previous GC identifers: GC19M056548 GC19M056109 GC19M060360 GC19M060376 GC19M052007


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT5 Gene:
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats
related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium.
Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium,
and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 (PubMed 7597049)).(supplied by
OMIM, Feb 2011)

GeneCards Summary for SYT5 Gene: 
SYT5 (synaptotagmin V) is a protein-coding gene. Diseases associated with SYT5 include thyroiditis, and pancreatitis, and among its related super-pathways are Regulation of Insulin Secretion and Metabolic pathways. GO annotations related to this gene include calcium-dependent phospholipid binding and protein heterodimerization activity. An important paralog of this gene is DOC2B.

UniProtKB/Swiss-Prot: SYT5_HUMAN, O00445
Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic
recycling compartment to the cell surface (By similarity)

Gene Wiki entry for SYT5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYT5 gene promoter:
         E2F-3a   E2F-1   E2F   NRSF form 1   E2F-2   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYT5 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYT5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q|11p   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q

SYT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M055684:  view genomic region     (about GC identifiers)

Start:
55,682,567 bp from pter      End:
55,691,809 bp from pter
Size:
9,243 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYT5_HUMAN, O00445 (See protein sequence)
Recommended Name: Synaptotagmin-5  
Size: 386 amino acids; 42900 Da
Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains (By similarity)
Subunit: Homodimer. Can also form heterodimers with SYT6. Interacts with both alpha- and beta-tubulin (By
similarity)
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane
protein (By similarity). Recycling endosome membrane; Single-pass membrane protein (By similarity). Note=In mast
cells, localizes to the endocytic recycling compartment (By similarity)
Secondary accessions: B3KWJ8 Q86X72

Explore the universe of human proteins at neXtProt for SYT5: NX_O00445

Explore proteomics data for SYT5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O00445

  • SYT5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYT5 Protein Expression
    REFSEQ proteins: NP_003171.2  
    ENSEMBL proteins: 
     ENSP00000465576   ENSP00000346265   ENSP00000442896   ENSP00000469874   ENSP00000465304  
     ENSP00000465074   ENSP00000467685   ENSP00000465110  
    Reactome Protein details: O00445
    Human Recombinant Protein Products for SYT5: 
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    Cloud-Clone Corp. Proteins for SYT5 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008021synaptic vesicle ----
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0030054cell junction IEA--
    GO:0030672synaptic vesicle membrane IEA--

    SYT5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SYT: Synaptotagmins

    5 InterPro protein domains:
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR001565 Synaptotagmin
     IPR018029 C2_membr_targeting
     IPR020477 C2_dom
     IPR000008 C2_Ca-dep

    Graphical View of Domain Structure for InterPro Entry O00445

    ProtoNet protein and cluster: O00445

    2 Blocks protein domains:
    IPB000008 C2 domain
    IPB001565 Synaptotagmin signature


    UniProtKB/Swiss-Prot: SYT5_HUMAN, O00445
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    SYT5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT5_HUMAN, O00445
    Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid
    binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
    Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic
    recycling compartment to the cell surface (By similarity)

         Genatlas biochemistry entry for SYT5:
    synaptotagmin 5,multifunctional intrinsic membrane protein of synaptic vesicles and chromaffin granules,involved
    in exocytosis and endocytosis

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005515protein binding ----
    GO:0005544calcium-dependent phospholipid binding IEA--
    GO:0019905syntaxin binding IEA--
    GO:0030276clathrin binding IEA--
         
    SYT5 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SYT5:
     Increased cell number in G2M,   Increased mitotic index 

         3 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Syt5):
     mortality/aging  nervous system  normal 

    SYT5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Syt5tm2.1Sud for SYT5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYT5 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SYT5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Regulation of Insulin Secretion
    Regulation of Insulin Secretion0.74
    Integration of energy metabolism0.74
    2Metabolism
    Metabolism0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3        Reactome Pathways for SYT5
        Metabolism
    Regulation of Insulin Secretion
    Integration of energy metabolism



    SYT5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYT5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for SYT5 (O004452, 3 ENSP000003462654) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLR2EP193882, 3, ENSP000002155874MINT-8267096 I2D: score=2 STRING: ENSP00000215587
    RAB1AP628202, 3MINT-63964 I2D: score=4 
    SYT3Q9BQG13, ENSP000003409144I2D: score=1 STRING: ENSP00000340914
    NRXN1Q9ULB13, ENSP000003851424I2D: score=1 STRING: ENSP00000385142
    INS-IGF2ENSP000003489864STRING: ENSP00000348986
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006112energy reserve metabolic process TAS--
    GO:0007268synaptic transmission TAS9177789
    GO:0044281small molecule metabolic process TAS--
    GO:0050796regulation of insulin secretion TAS--

    SYT5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for SYT5

    2 HMDB Compounds for SYT5    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Norepinephrine(-)-(R)-Norepinephrine (see all 32)51-41-2--

    Search CenterWatch for drugs/clinical trials and news about SYT5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYT5 gene: 
    NM_003180.2  

    Unigene Cluster for SYT5:

    Synaptotagmin V
    Hs.631566  [show with all ESTs]
    Unigene Representative Sequence: AK125182
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000590851 ENST00000354308(uc002qjn.1 uc002qjo.1) ENST00000592935
    ENST00000537500(uc002qjm.1 uc002qjp.2) ENST00000588305 ENST00000592956
    ENST00000590859 ENST00000587067 ENST00000585461 ENST00000589172 ENST00000592470

    miRNA
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    hsa-miR-330-3p hsa-miR-219-5p hsa-miR-486-3p hsa-miR-508-3p
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    Additional mRNA sequence: 

    AK125182.1 AK295337.1 AK313067.1 BC029962.1 BC033683.1 BC046157.1 DQ090951.1 Y19236.1 

    7 DOTS entries:

    DT.100028207  DT.100751864  DT.91717535  DT.99999711  DT.100028208  DT.100680535  DT.97770048 

    24/125 AceView cDNA sequences (see all 125):

    BX281263 BC033683 CA438375 CA950706 BQ286572 BM310671 CK825116 BQ286747 
    BU784948 BM547597 BQ288023 BM353597 BM311596 BU952031 AI569711 AI916821 
    BM314840 CA843197 BI751997 CA951045 AI638801 BU069281 CR597766 BU952292 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SYT5 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
    SP1:        -                                   -                                                               
    SP2:                                            -                                                               
    SP3:        -     -                             -                                                               
    SP4:                                            -                                                               
    SP5:                                      -     -                                                               


    ECgene alternative splicing isoforms for SYT5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYT5 expression in normal human tissues (normalized intensities)      SYT5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGCCAACC
    SYT5 Expression
    About this image


    SYT5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/10 selected tissues (see all 10) fully expand
     
     Brain (Nervous System)    fully expand to see all 19 entries
             Thalamus
             postcentral gyrus   
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Telencephalon
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 2 entries
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             spinal/ganglion/dorsal root ganglion   
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose   

    See SYT5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYT5

    SOURCE GeneReport for Unigene cluster: Hs.631566
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SYT5 gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt51 , 5 synaptotagmin V1, 5 85.49(n)1
    91.19(a)1
      7 (2.62 cM)5
    534201  NM_016908.21  NP_058604.11 
     45397685 
    fruit fly
    (Drosophila melanogaster)
    Insecta syt3 larval locomotory behavior
    calcium-dependent phospholipid more
    59(a)
    (best of 3)
        --


    ENSEMBL Gene Tree for SYT5 (if available)
    TreeFam Gene Tree for SYT5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYT5 gene
    DOC2B2  SYT42  SYT92  SYT82  SYT102  SYT32  SYT62  SYT172  
    SYT112  SYT122  SYT22  DOC2A2  SYT72  RPH3A2  SYT12  
    18/20 SIMAP similar genes for SYT5 using alignment to 8 protein entries:     SYT5_HUMAN (see all proteins) (see all similar genes):
    SYT2    SYT1    PRKCG    SYT10    SYT3    SYT7
    SYT6    SYT4    SYT17    SYT11    DOC2A    SYT9
    DKFZp434D2429    SYT12    SYT8    CHR11SYT    SYT15    UNC13D

    SYT5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/262 SNPs in SYT5 are shown (see all 262)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs72586591,2
    C,F,H--55683977(+) TTCCCT/CGGCTC 1 -- int112Minor allele frequency- C:0.04NS EA NA WA 1312
    rs750022231,2
    F--55684169(+) GCAAGC/TGAGTG 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1143678841,2
    F--55684186(+) TTCATG/AGACAA 1 -- int11Minor allele frequency- A:0.03WA 118
    rs37868671,2
    C,F,H--55684200(-) GAGAAC/TTCCCT 1 -- int118Minor allele frequency- T:0.27NS EA NA WA 2342
    rs1894394981,2
    --55684218(+) CCTCAA/CAGCCA 1 -- int10--------
    rs37868661,2
    C,F,A,H--55684224(-) ACACGT/CTGGCT 1 -- int116Minor allele frequency- C:0.50NS EA NA WA CSA 1074
    rs1146934431,2
    F--55684226(+) CCAGCG/ATGTGG 1 -- int11Minor allele frequency- A:0.03WA 118
    rs736195421,2
    C,F--55684312(+) TGAGAG/CTGTGA 1 -- int12Minor allele frequency- C:0.21WA 120
    rs1807857261,2
    --55684316(+) AGTGTC/GAGGGA 1 -- int10--------
    rs72582871,2
    C,F,H--55684388(+) GCGAGC/TGCCCA 1 -- int111Minor allele frequency- T:0.04NS EA WA NA 1298

    HapMap Linkage Disequilibrium report for SYT5 (55682567 - 55691809 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SYT5:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv912453CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600782    OMIM disorders: --

    4 diseases for SYT5:    About MalaCards
    thyroiditis    pancreatitis    breast cancer    neuronitis


    SYT5 for disorders           About GeneDecksing


    Export disorders for SYT5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYT5 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SYT5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location. (PubMed id 9177789)1, 2, 3, 9 Craxton M.A.... Goedert M. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Evidence for the association of synaptotagmin with glutathione S-transferases: implications for a novel function in human breast cancer. (PubMed id 15820774)1, 9 Sreenath A.S....Reddanna P. (2005)
    5. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    6. Cloning, expression, purification, crystallization and preliminary X-ray diffraction crystallographic study of human synaptotagmin 5 C 2A domain. (PubMed id 22102235)1 Qiu X....Gao Y. (2011)
    7. Proteome analysis of the thalamus and cerebrospinal f luid reveals glycolysis dysfunction and potential biomarkers candidates for sch izophrenia. (PubMed id 20471030)1 Martins-de-Souza D....Turck C.W. (2010)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6861 HGNC: 11513 AceView: SYT5 Ensembl:ENSG00000129990 euGenes: HUgn6861
    ECgene: SYT5 H-InvDB: SYT5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYT5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYT5 gene:
    Search GeneIP for patents involving SYT5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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