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Aliases for SYT17 Gene

Aliases for SYT17 Gene

  • Synaptotagmin XVII 2 3 4
  • B/K Protein 2 3
  • Protein B/K 3 4
  • SytXVII 3 4
  • Synaptotagmin-17 3

External Ids for SYT17 Gene

Previous GeneCards Identifiers for SYT17 Gene

  • GC16P019088
  • GC16P017717

Summaries for SYT17 Gene

GeneCards Summary for SYT17 Gene

SYT17 (Synaptotagmin XVII) is a Protein Coding gene. GO annotations related to this gene include transporter activity. An important paralog of this gene is SYT5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SYT17 Gene

Genomics for SYT17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SYT17 Gene

19,167,971 bp from pter
19,268,334 bp from pter
100,364 bases
Plus strand

Genomic View for SYT17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SYT17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SYT17 Gene

Proteins for SYT17 Gene

  • Protein details for SYT17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • O43330
    • Q9NZ18

    Protein attributes for SYT17 Gene

    474 amino acids
    Molecular mass:
    53849 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for SYT17 Gene

neXtProt entry for SYT17 Gene

Proteomics data for SYT17 Gene at MOPED

Post-translational modifications for SYT17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for SYT17 Gene

Domains for SYT17 Gene

Gene Families for SYT17 Gene

  • SYT :Synaptotagmins

Protein Domains for SYT17 Gene

Suggested Antigen Peptide Sequences for SYT17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BSW7
  • Contains 2 C2 domains.
  • Belongs to the synaptotagmin family.
genes like me logo Genes that share domains with SYT17: view

Function for SYT17 Gene

Gene Ontology (GO) - Molecular Function for SYT17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity --
GO:0005509 calcium ion binding IBA --
GO:0005515 protein binding IPI 16189514
GO:0005544 calcium-dependent phospholipid binding IBA --
GO:0019905 syntaxin binding IBA --
genes like me logo Genes that share ontologies with SYT17: view

miRNA for SYT17 Gene

miRTarBase miRNAs that target SYT17

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SYT17

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SYT17 Gene

Localization for SYT17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SYT17 Gene

Membrane; Peripheral membrane protein.

Subcellular locations from

Jensen Localization Image for SYT17 Gene COMPARTMENTS Subcellular localization image for SYT17 gene
Compartment Confidence
cytosol 3
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SYT17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005802 trans-Golgi network IEA --
GO:0005886 plasma membrane IBA --
GO:0008021 synaptic vesicle --
GO:0016020 membrane --
genes like me logo Genes that share ontologies with SYT17: view

Pathways for SYT17 Gene

SuperPathways for SYT17 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SYT17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006887 exocytosis --
GO:0006906 vesicle fusion IBA --
GO:0016079 synaptic vesicle exocytosis IBA --
GO:0017158 regulation of calcium ion-dependent exocytosis IBA --
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter IBA --
genes like me logo Genes that share ontologies with SYT17: view

No data available for Pathways by source for SYT17 Gene

Transcripts for SYT17 Gene

Unigene Clusters for SYT17 Gene

Synaptotagmin XVII:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SYT17

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SYT17 Gene

No ASD Table

Relevant External Links for SYT17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SYT17 Gene

mRNA expression in normal human tissues for SYT17 Gene

mRNA differential expression in normal tissues according to GTEx for SYT17 Gene

This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (5.1) and Brain - Amygdala (4.1).

Protein differential expression in normal tissues for SYT17 Gene

This gene is overexpressed in Fetal Brain (47.2) and Frontal cortex (21.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SYT17 Gene

SOURCE GeneReport for Unigene cluster for SYT17 Gene Hs.258326

mRNA Expression by UniProt/SwissProt for SYT17 Gene

Tissue specificity: Expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra, and pituitary), kidney, and prostate. Expressed in fetal brain, kidney and lung.
genes like me logo Genes that share expressions with SYT17: view

Expression partners for SYT17 Gene

In Situ Assay Products

Orthologs for SYT17 Gene

This gene was present in the common ancestor of animals.

Orthologs for SYT17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SYT17 35
  • 90.86 (n)
  • 96.41 (a)
SYT17 36
  • 96 (a)
(Canis familiaris)
Mammalia SYT17 35
  • 91.91 (n)
  • 98.3 (a)
-- 36
  • 84 (a)
-- 36
  • 72 (a)
(Mus musculus)
Mammalia Syt17 35
  • 88.13 (n)
  • 96.16 (a)
Syt17 16
Syt17 36
  • 96 (a)
(Pan troglodytes)
Mammalia SYT17 35
  • 97.79 (n)
  • 97.62 (a)
SYT17 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Syt17 35
  • 87.9 (n)
  • 96.84 (a)
(Monodelphis domestica)
Mammalia SYT17 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia SYT17 36
  • 90 (a)
(Gallus gallus)
Aves SYT17 35
  • 74.27 (n)
  • 81.24 (a)
SYT17 36
  • 81 (a)
(Anolis carolinensis)
Reptilia SYT17 36
  • 87 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia syt17 35
  • 76.23 (n)
  • 87.76 (a)
(Danio rerio)
Actinopterygii LOC100000374 35
  • 70.76 (n)
  • 74.15 (a)
SYT17 36
  • 73 (a)
fruit fly
(Drosophila melanogaster)
Insecta Sytalpha 36
  • 25 (a)
Species with no ortholog for SYT17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SYT17 Gene

Gene Tree for SYT17 (if available)
Gene Tree for SYT17 (if available)

Paralogs for SYT17 Gene

Paralogs for SYT17 Gene

genes like me logo Genes that share paralogs with SYT17: view

Variants for SYT17 Gene

Sequence variations from dbSNP and Humsavar for SYT17 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs11343 -- 19,268,142(-) ACAGA(A/C)AAACA utr-variant-3-prime
rs81107 -- 19,214,504(+) CCTCG(C/T)CAGCT intron-variant
rs81108 -- 19,215,374(+) GAATC(C/T)TCACT intron-variant
rs229005 -- 19,202,115(+) tcata(C/T)ggaca intron-variant
rs229006 -- 19,202,981(+) tgtaa(G/T)tgttc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SYT17 Gene

Variant ID Type Subtype PubMed ID
nsv436835 CNV Insertion 17901297
esv998101 CNV Deletion 20482838
esv2550711 CNV Deletion 19546169
esv2418352 CNV Deletion 18987734
esv5037 CNV Deletion 18987735
esv2714047 CNV Deletion 23290073
esv993801 CNV Deletion 20482838
esv1661893 CNV Deletion 17803354
esv8609 CNV Loss 19470904
nsv833162 CNV Loss 17160897

Relevant External Links for SYT17 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SYT17 Gene

Disorders for SYT17 Gene

Relevant External Links for SYT17

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SYT17 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SYT17 Gene

Publications for SYT17 Gene

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Protein kinase A-dependent phosphorylation of B/K protein. (PMID: 16672768) Chin H. … Kwon O.-J. (Exp. Mol. Med. 2006) 3 4
  4. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3
  5. A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. (PMID: 16730941) Tsang H.T.H. … Sanderson C.M. (Genomics 2006) 3

Products for SYT17 Gene

Sources for SYT17 Gene

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