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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SYT17 Gene

protein-coding GIFtS: 48
GCID: GC16P019179

synaptotagmin XVII

Explore 3 diseases affiliated with
SYT17 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Synaptotagmin XVII¹ ² ³
Protein B/K² ³
B/K Protein²
Synaptotagmin-17¹
SytXVII³
SytXVII³

External Ids:	HGNC: 24119¹	Entrez Gene: 51760²	Ensembl: ENSG00000103528⁷	UniProtKB: Q9BSW7³

Export aliases for SYT17 gene to outside databases

Previous GC identifers: GC16P019088 GC16P017717

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SYT17 gene promoter:
LHX3b/Lhx3b Pax-5 NF-kappaB LCR-F1 c-Ets-1 PPAR-gamma1 LHX3a/Lhx3a PPAR-gamma2 NF-kappaB1 ATF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYT17 promoter sequence

Search SABiosciences Chromatin IP Primers for SYT17

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT17

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.3 Ensembl cytogenetic band: 16p12.3 HGNC cytogenetic band: 16p12.3

SYT17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT17 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P019179: view genomic region (about GC identifiers)

Start:	19,179,293 bp from pter	End:	19,279,652 bp from pter
Size:	100,360 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYT17_HUMAN, Q9BSW7 (See protein sequence)

Recommended Name: Synaptotagmin-17

Size: 474 amino acids; 53849 Da

Subcellular location: Membrane; Peripheral membrane protein (By similarity)

1 PDB 3D structure from and Proteopedia for SYT17:

2ENP (3D)

Secondary accessions: O43330 Q9NZ18

Explore the universe of human proteins at neXtProt for SYT17: NX_Q9BSW7

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BSW7

SYT17 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057608.2

ENSEMBL proteins:

ENSP00000456790 ENSP00000454335 ENSP00000347538 ENSP00000456009 ENSP00000456252

ENSP00000454721 ENSP00000456879 ENSP00000456915

Human Recombinant Protein Products for SYT17:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SYT17 OriGene Protein Over-expression Lysate: SYT17 OriGene Custom Protein Services for SYT17
	GenScript Custom Purified and Recombinant Proteins Services for SYT17
	Novus Biologicals SYT17 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SYT17

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005802	trans-Golgi network	IEA	--
GO:0008021	synaptic vesicle	IEA	--
GO:0016020	membrane	IEA	--

SYT17 for ontologies About GeneDecksing

SYT17 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for SYT17
	Novus Biologicals SYT17 Antibodies
	Abcam antibodies for SYT17
	Uscn Antibodies for SYT17
	Search ThermoFisher Antibodies for SYT17

Assay Products for SYT17:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SYT17
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SYT17

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SYT17 for domains About GeneDecksing

5 InterPro domains/families:

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR014705 BKprotein

IPR001565 Synaptotagmin

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry Q9BSW7

ProtoNet protein and cluster: Q9BSW7

2 Blocks protein families:

IPB000008 C2 domain

IPB001565 Synaptotagmin signature

UniProtKB/Swiss-Prot: SYT17_HUMAN, Q9BSW7

Similarity: Belongs to the synaptotagmin family

Similarity: Contains 2 C2 domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	IEA	--

SYT17 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SYT17

miRNA Products:		OriGene 3'-UTR Clone: SYT17 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT17
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT17:
		hsa-miR-4297 hsa-miR-642b
		SwitchGear 3'UTR luciferase reporter plasmid: SYT17 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT17 (see all 7) OriGene shRNA RFP: SYT17 OriGene siRNA: SYT17
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT17
		Sirion Biotech Custom design and validation of potent shRNA sequences against SYT17

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SYT17
			Sirion Biotech Customized adenovirus for overexpression of SYT17 Sirion Biotech Customized adenovirus for potent knockdown of SYT17

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SYT17 (NM_016524)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT17
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT17

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SYT17
		Search LifeMap BioReagents cell lines for SYT17
		Sirion Biotech Customized stable knockdown cell line services for SYT17 Sirion Biotech Customized inducible knockdown cell line services for SYT17 Sirion Biotech Customized stable overexpressing cell line services for SYT17 Sirion Biotech Customized inducible overexpressing cell line services for SYT17

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT17

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SYT17

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/7 Interacting proteins for SYT17 (Q9BSW7^{2, 3} ENSP00000347538⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CCDC85B	Q15834²^,³, ENSP00000311695⁴	MINT-66651 I2D: score=5 STRING: ENSP00000311695
NINL	Q9Y2I6²^,³, ENSP00000278886⁴	MINT-67395 I2D: score=5 STRING: ENSP00000278886
APTX	Q7Z2E3²^,³, ENSP00000400806⁴	MINT-2873647 I2D: score=3 STRING: ENSP00000400806
MDP1	Q86V88²^,³, ENSP00000288087⁴	MINT-67169 I2D: score=1 STRING: ENSP00000288087
TSC22D4	Q9Y3Q8²^,³, ENSP00000300181⁴	MINT-67942 I2D: score=5 STRING: ENSP00000300181

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SYT17
Search CenterWatch for drugs/clinical trials and news about SYT17

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SYT17 gene:

NM_016524.2

Unigene Cluster for SYT17:

Synaptotagmin XVII

Hs.258326 [show with all ESTs]

Unigene Representative Sequence: AK226136

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000570264 ENST00000566261 ENST00000355377(uc002dfw.3) ENST00000568115

ENST00000562034(uc002dfx.3 uc002dfy.3) ENST00000562711 ENST00000562274

ENST00000565183 ENST00000568433

miRNA Products:		OriGene 3'-UTR Clone: SYT17 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT17
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT17:
		hsa-miR-4297 hsa-miR-642b
		SwitchGear 3'UTR luciferase reporter plasmid: SYT17 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT17 (see all 7) OriGene shRNA RFP: SYT17 OriGene siRNA: SYT17
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT17
		Sirion Biotech Custom design and validation of potent shRNA sequences against SYT17

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SYT17 (NM_016524)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT17
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT17

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT17 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYT17
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT17
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT17

Additional cDNA sequence:

AF220560.1 AK098747.1 AK226136.1 AK296000.1 BC004518.2

9 DOTS entries:

DT.110320 DT.97837404 DT.100695793 DT.120688358 DT.92421583 DT.75162435 DT.120688318 DT.40131551

DT.97804350

24/89 AceView cDNA sequences (see all 89):

BQ267300 AI568084 BF942106 BQ070945 AA250917 AW136805 AK098747 BX106395

NM_016524 AA372001 Z41994 BM982070 H23376 CA771221 BM714007 BC004518

AA253461 CR595216 BQ272543 AI654652 BF196505 BX088745 CA771529 BQ548669

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SYT17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCAACACGC

About this image

SYT17 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Skeletal Muscle

Hyoid Arch Muscles

Muscle Progenitor Cells

Skeletal Muscle

Mandibular Arch Muscles

Muscle Progenitor Cells

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SYT17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYT17

SOURCE GeneReport for Unigene cluster: Hs.258326

UniProtKB/Swiss-Prot: SYT17_HUMAN, Q9BSW7

Tissue specificity: Expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala,

substantia nigra, and pituitary), kidney, and prostate. Expressed in fetal brain, kidney and lung

SABiosciences Custom PCR Arrays for SYT17

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT17 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYT17
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT17
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT17

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT17

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SYT17 gene from 4/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SYT17¹	synaptotagmin XVII	75.38(n) 82.14(a)		416608 XM_414910.3 XP_414910.3
lizard (Anolis carolinensis)	Reptilia	SYT17⁶	--	86(a)	1 ↔ 1	GL343769.1(203791-214132)
zebrafish (Danio rerio)	Actinopterygii	LOC100000374¹	synaptotagmin-17-like	71.08(n) 74.57(a)		100000374 XM_001922473.3 XP_001922508.3
worm (Caenorhabditis elegans)	Secernentea	snt-6⁶ snt-5⁶	SyNapTotagmin family member (snt-5)	23(a) 20(a)	possible ortholog 1 ↔ 1	II(745469-750171) V(1393125-1411623)

ENSEMBL Gene Tree for SYT17 (if available)
TreeFam Gene Tree for SYT17 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SYT17 gene

SYT15² SYT4² SYT5² SYT8² SYT9² SYT3² SYT10² SYT6²

SYT11² SYT2² SYT12² SYT7² SYT1²

12 SIMAP similar genes for SYT17 using alignment to 8 protein entries: SYT17_HUMAN (see all proteins):

SYT2 SYT1 SYT5 SYT7 CHR11SYT SYT10

SYT11 SYT9 SYT4 DKFZp434D2429 SYT6 SYT15

SYT17 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2004163^1,2		--	19177639(-)	`ggaggC/Tggagg`	1	--	us2k¹		0	--	--	--	--
rs141779391^1,2		--	19177694(+)	`GATTAC/TAGGCA`	1	--	us2k¹		0	--	--	--	--
rs150144955^1,2		--	19177715(+)	`TGCCCA/GGCTAT`	1	--	us2k¹		0	--	--	--	--
rs182086182^1,2		--	19177743(+)	`GAGACA/GGAGTT`	1	--	us2k¹		0	--	--	--	--
rs186679259^1,2		--	19177773(+)	`GATCTC/TGAACT`	1	--	us2k¹		0	--	--	--	--
rs138573378^1,2		--	19177785(+)	`CTGACC/TTCAGG`	1	--	us2k¹		0	--	--	--	--
rs114379545^1,2	F	--	19177816(+)	`TTACTT/CATGGG`	1	--	us2k¹		1		WA	118
rs77893923^1,2		--	19177872(+)	`CACCCG/ATTCCA`	1	--	us2k¹		1		WA	118
rs192351355^1,2		--	19177919(+)	`GGCATA/GCCTTG`	1	--	us2k¹		0	--	--	--	--
rs200980025^1,2		--	19177983(+)	`GCCAC-/TTTGGGT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SYT17 (19179293 - 19279652 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for SYT17
2 CNVs: 102223 87995
5 Indels: 61495 45405 40133 25624 42561

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT17

DNA2.0 Custom Variant and Variant Library Synthesis for SYT17

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SYT17 for disorders About GeneDecksing

3 diseases for SYT17: About MalaCards

choroiditis ataxia prostatitis

Human Genome Epidemiology (HuGE) Navigator: SYT17 (1 document)

Export disorders for SYT17 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SYT17 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with SYT17)

Utopia: connect your pdf to the dynamic
world of online information

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)^{1, 2, 3} Loftus B.J.... Adams M.D. (1999)
Protein kinase A-dependent phosphorylation of B/K protein. (PubMed id 16672768)^{1, 2} Chin H.... Kwon O.-J. (2006)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Confirmation of prior evidence of genetic susceptibili ty to alcoholism in a genome-wide association study of comorbid alcoholism and b ipolar disorder. (PubMed id 21876473)¹ Lydall G.J....Gurling H.M. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. (PubMed id 16730941)¹ Tsang H.T.H....Sanderson C.M. (2006)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)¹ Lim J.... Zoghbi H.Y. (2006)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)¹ Rual J.F....Vidal M. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51760	HGNC: 24119	AceView: LOC51760	Ensembl:ENSG00000103528	euGenes: HUgn51760
ECgene: SYT17	H-InvDB: SYT17

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SYT17	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SYT17 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SYT17 gene:
Search GeneIP for patents involving SYT17

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for SYT17
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT17		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT17
	OriGene Protein Over-expression Lysate for SYT17		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SYT17		OriGene 3'-UTR Clone for SYT17
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT17
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for SYT17		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYT17
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT17
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT17
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT17
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT17
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT17

	GenScript Custom Purified and Recombinant Proteins Services for SYT17		GenScript cDNA clones with any tag delivered in your preferred vector for SYT17
	GenScript Custom Assay Services for SYT17		GenScript Custom Superior Antibodies Services for SYT17
	GenScript Custom overexpressing Cell Line Services for SYT17		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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SYT17 Proteins, Antibodies, CLIAs, and ELISAs

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT17

	SwitchGear 3'UTR luciferase reporter plasmids for SYT17
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Search ThermoFisher Antibodies for SYT17

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT17

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SYT17

Sirion Biotech Customized:

	stable knockdown cell line services for SYT17
	inducible knockdown cell line services for SYT17
	design and validation of potent shRNA sequences against SYT17
	adenovirus for potent knockdown of SYT17
	adenovirus for overexpression of SYT17
	stable overexpressing cell line services for SYT17
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SYT17 gene at Home site.

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SYT17 Gene

synaptotagmin XVII

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SYT17 Gene

synaptotagmin XVII

Aliasesfor SYT17 gene

Summariesfor SYT17 gene

Genomic Viewsfor SYT17 gene

Proteinsfor SYT17 gene

Protein Domains /Familiesfor SYT17 gene

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for SYT17 gene

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for SYT17 gene

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for SYT17 gene

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for SYT17 gene

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for SYT17 gene

Transcripts
for SYT17 gene

Expression
for SYT17 gene

Orthologs
for SYT17 gene

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for SYT17 gene

Genomic Variants
for SYT17 gene

Disorders / Diseases
for SYT17 gene

Publications
for SYT17 gene

Intellectual Property
for SYT17 gene

Products
for SYT17 gene