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SYT16 Gene

protein-coding   GIFtS: 49
GCID: GC14P062462

Synaptotagmin XVI

(Previous name: synaptotagmin XIV-like)
(Previous symbol: SYT14L)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synaptotagmin XVI1 2     CHR14SYT2
SYT14L1 2 3     Strep142
Synaptotagmin 14-Like Protein2 3     Chr14 Synaptotagmin2
Synaptotagmin XIV-Related Protein2 3     synaptotagmin-162
STREP143 5     syt14r2
Chr14 Synaptotagmin1     yt14r2
Synaptotagmin XIV-Like1     Chr14Syt3
Synaptotagmin XIV-Related1     SYT14R3

External Ids:    HGNC: 231421   Entrez Gene: 838512   Ensembl: ENSG000001399737   OMIM: 6109505   UniProtKB: Q17RD73   

Export aliases for SYT16 gene to outside databases

Previous GC identifers: GC14P061533 GC14P042626


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SYT16 Gene:
SYT16 (synaptotagmin XVI) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and protein homodimerization activity. An important paralog of this gene is SYT14.

UniProtKB/Swiss-Prot: SYT16_HUMAN, Q17RD7
Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is
Ca(2+)-independent




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYT16 gene promoter:
         AML1a   Pax-2   Pax-2a   Nkx2-5   Meis-1b   AREB6   Nkx6-1   Pax-2b   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYT16 promoter sequence
   Search Chromatin IP Primers for SYT16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYT16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.2   Ensembl cytogenetic band:  14q23.2   HGNC cytogenetic band: 14q23.2

SYT16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT16 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P062462:  view genomic region     (about GC identifiers)

Start:
62,453,803 bp from pter      End:
62,568,431 bp from pter
Size:
114,629 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SYT16_HUMAN, Q17RD7 (See protein sequence)
Recommended Name: Synaptotagmin-16  
Size: 645 amino acids; 72274 Da
Subunit: Homodimer. Can also form heterodimers (By similarity)
Sequence caution: Sequence=CAE85114.1; Type=Erroneous termination; Positions=72; Note=Translated as Gln;
Secondary accessions: B7ZL60 C9J8I3 Q707N2 Q7Z441 Q8IUU0 Q9BQR8
Alternative splicing: 3 isoforms:  Q17RD7-1   Q17RD7-2   Q17RD7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYT16: NX_Q17RD7

Explore proteomics data for SYT16 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SYT16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114120.2  
    ENSEMBL proteins: 
     ENSP00000394700   ENSP00000451035   ENSP00000388023  

    SYT16 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SYT16

     
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    Search eBioscience for ELISAs for SYT16 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SYT: Synaptotagmins

    2 InterPro protein domains:
     IPR028690 SYT16
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q17RD7

    ProtoNet protein and cluster: Q17RD7

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: SYT16_HUMAN, Q17RD7
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    Find genes that share domains with SYT16           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT16_HUMAN, Q17RD7
    Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is
    Ca(2+)-independent

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005543phospholipid binding IEA--
    GO:0042803protein homodimerization activity IEA--
    GO:0046982protein heterodimerization activity IEA--
         
    Find genes that share ontologies with SYT16           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SYT16:
     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYT16
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYT16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYT16

    miRNA
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    Block miRNA regulation of human, mouse, rat SYT16 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate SYT16:
    hsa-miR-299-5p hsa-miR-374c hsa-miR-587 hsa-miR-4311 hsa-miR-655 hsa-miR-3658 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidSYT16 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SYT16
    Predesigned siRNA for gene silencing in human, mouse, rat SYT16

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    GenScript: all cDNA clones in your preferred vector: SYT16 (NM_031914)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT16

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYT16
    Interactions:

        Search GeneGlobe Interaction Network for SYT16

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SYT16 (Q17RD73 ENSP000003947004) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SYT14Q8NB593, ENSP000004189014I2D: score=2 STRING: ENSP00000418901
    --ENSP000003889494STRING: ENSP00000388949
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006887exocytosis IEA--

    Find genes that share ontologies with SYT16           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYT16



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYT16 gene: 
    NM_031914.2  

    Unigene Cluster for SYT16:

    Synaptotagmin XVI
    Hs.404139  [show with all ESTs]
    Unigene Representative Sequence: AJ617628
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000430451(uc001xfu.1) ENST00000555409(uc010tse.1) ENST00000446982(uc010tsd.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SYT16 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate SYT16:
    hsa-miR-299-5p hsa-miR-374c hsa-miR-587 hsa-miR-4311 hsa-miR-655 hsa-miR-3658 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidSYT16 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SYT16
    Predesigned siRNA for gene silencing in human, mouse, rat SYT16
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    OriGene ORF clones in mouse, rat for SYT16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYT16 (NM_031914)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT16
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SYT16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SYT16
      QuantiTect SYBR Green Assays in human, mouse, rat SYT16
      QuantiFast Probe-based Assays in human, mouse, rat SYT16

    Additional mRNA sequence: 

    AB102949.1 AJ303367.1 AJ617628.1 AK302919.1 BC040924.1 BC117363.1 BC143598.1 

    4 DOTS entries:

    DT.101978522  DT.97803587  DT.100691869  DT.120753215 

    7 AceView cDNA sequences:

    AB102949 BM927053 AJ303367 BC040924 NM_031914 AJ617628 AI970973 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYT16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTTTTTAA
    SYT16 Expression
    About this image


    SYT16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Limb (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Bone (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Cartilage (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Pancreas (Endocrine System)
    SYT16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYT16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.404139

    UniProtKB/Swiss-Prot: SYT16_HUMAN, Q17RD7
    Tissue specificity: Expressed in brain

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SYT16 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt161 , 5 synaptotagmin XVI1, 5 84.33(n)1
    82.55(a)1
      12 (32.02 cM)5
    2382661  NM_172804.21  NP_766392.21 
     739977615 
    chicken
    (Gallus gallus)
    Aves SYT161 synaptotagmin XVI 65.05(n)
    58.13(a)
      423516  XM_421415.4  XP_421415.4 
    lizard
    (Anolis carolinensis)
    Reptilia SYT166
    synaptotagmin XVI
    50(a)
    1 ↔ 1
    1(3041311-3160665)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.100612 Transcribed sequence with weak similarity to protein more 79.31(n)    141992148 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5587251 novel protein similar to H.sapiens SYT16, synaptotagmin more 62.93(n)
    57.54(a)
      558725  XM_003199742.2  XP_003199790.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syt146
    Synaptotagmin 14
    29(a)
    1 → many
    3R(141310-144791)
    worm
    (Caenorhabditis elegans)
    Secernentea D2023.36
    Protein D2023.3, isoform b (D2023.3) mRNA, complet...
    24(a)
    1 → many
    V(11802105-11812012) WBGene00008407


    ENSEMBL Gene Tree for SYT16 (if available)
    TreeFam Gene Tree for SYT16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYT16 gene
    SYT142  
    2 SIMAP similar genes for SYT16 using alignment to 2 protein entries:     SYT16_HUMAN (see all proteins):
    SYT14L    SYT14

    Find genes that share paralogs with SYT16           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYT16 (see all 2492)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1417572001,2
    --62460552(+) GGTGTC/TGTTTT 1 -- us2k10--------
    rs1864306291,2
    --62460598(+) TCACTA/GTGTGC 1 -- us2k10--------
    rs780080641,2
    F--62460667(+) TCCAGG/AGAGCC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs794794541,2
    C--62460746(+) ATTGAA/GTCTGG 1 -- us2k10--------
    rs1144312851,2
    C,F--62460764(+) GAGCAT/CATGAA 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1908494631,2
    C--62460765(+) AGCATA/GTGAAG 1 -- us2k10--------
    rs118446871,2
    C,F,H--62460775(+) GCGAAC/TTAGGT 1 -- us2k16Minor allele frequency- T:0.08NS EA CSA WA 540
    rs1823309941,2
    --62461264(+) TAATTG/TAAATG 1 -- us2k10--------
    rs1851749091,2
    --62461274(+) GTAGGA/GATGGG 1 -- us2k10--------
    rs1915017081,2
    --62461413(+) GGGGAA/TATGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SYT16 (62453803 - 62568431 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SYT16:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1303CNV Insertion18451855
    nsv456321CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYT16
    DNA2.0 Custom Variant and Variant Library Synthesis for SYT16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610950    OMIM disorders: --


    Find genes that share disorders with SYT16           About GenesLikeMe

    Genetic Association Database (GAD): SYT16
    Human Genome Epidemiology (HuGE) Navigator: SYT16 (1 document)

    Export disorders for SYT16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYT16 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SYT16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic analysis of synaptotagmin genes. (PubMed id 11543631)1, 2, 3 Craxton M.A. (Genomics 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Synaptotagmin gene content of the sequenced genomes. (PubMed id 15238157)1, 2 Craxton M.A. (BMC Genomics 2004)
    5. Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans. (PubMed id 12801916)1, 2 Fukuda M. (J. Biochem. 2003)
    6. A genome-wide association study of self-rated health. (PubMed id 20707712)1 Mosing M.A....Martin N.G. (Twin Res Hum Genet 2010)
    7. Purification, crystallization and X-ray diffraction analysis of human synaptotagmin 1 C2A-C2B. (PubMed id 16946482)1 Montes M....Robert J.J. (Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2006)
    8. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)2 Heilig R.... Weissenbach J. (Nature 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83851 HGNC: 23142 AceView: SYT14L Ensembl:ENSG00000139973 euGenes: HUgn83851
    ECgene: SYT16 H-InvDB: SYT16

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYT16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYT16 gene:
    Search GeneIP for patents involving SYT16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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