Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYT15 Gene

protein-coding   GIFtS: 42
GCID: GC10M046955

Synaptotagmin XV

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synaptotagmin XV1 2 3     synaptotagmin-152
CHR10SYT2     sytXV2
Chr10 Synaptotagmin2     Chr10Syt3
Synaptotagmin XV-A2     SytXV3

External Ids:    HGNC: 171671   Entrez Gene: 838492   Ensembl: ENSG000002041767   OMIM: 6080815   UniProtKB: Q9BQS23   

Export aliases for SYT15 gene to outside databases

Previous GC identifers: GC10U900263 GC10M046339 GC10M046378 GC10M042810


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT15 Gene:
This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this
family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the
encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding
distinct isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for SYT15 Gene: 
SYT15 (synaptotagmin XV) is a protein-coding gene. Diseases associated with SYT15 include neuronitis. An important paralog of this gene is SYT13.

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2
Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_031847.8  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYT15 gene promoter:
         RFX1   USF1   AML1a   GATA-2   E2F-1   E2F   USF-1   STAT3   c-Myb   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYT15 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYT15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.1   Ensembl cytogenetic band:  10q11.22   HGNC cytogenetic band: 10q11.1

SYT15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT15 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M046955:  view genomic region     (about GC identifiers)

Start:
46,955,444 bp from pter      End:
46,971,400 bp from pter
Size:
15,957 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2 (See protein sequence)
Recommended Name: Synaptotagmin-15  
Size: 421 amino acids; 47375 Da
Subunit: Homodimer (By similarity)
Subcellular location: Isoform 1: Cell membrane; Single-pass type III membrane protein (By similarity)
Subcellular location: Isoform 2: Cell membrane; Single-pass type III membrane protein (By similarity)
Subcellular location: Isoform 4: Cell membrane; Single-pass type III membrane protein (By similarity)
Secondary accessions: A5D6W8 Q5VY53 Q5VY55 Q7Z439 Q7Z440
Alternative splicing: 4 isoforms:  Q9BQS2-1   Q9BQS2-2   Q9BQS2-3   Q9BQS2-4   

Explore the universe of human proteins at neXtProt for SYT15: NX_Q9BQS2

Explore proteomics data for SYT15 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BQS2

  • SYT15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYT15 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_114118.2  NP_852660.1  

    ENSEMBL proteins: 
     ENSP00000363448   ENSP00000427607   ENSP00000363443   ENSP00000363441   ENSP00000424803  
     ENSP00000363445  

    Human Recombinant Protein Products for SYT15: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SYT15
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SYT15
    GenScript Custom Purified and Recombinant Proteins Services for SYT15
    Novus Biologicals SYT15 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SYT15 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0008021synaptic vesicle ----
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0019898extrinsic to membrane IEA--

    SYT15 for ontologies           About GeneDecksing



    SYT15 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SYT15
    GenScript Custom Superior Antibodies Services for SYT15
    Search for Antibodies for SYT15 at Abcam
    Cloud-Clone Corp. Antibodies for SYT15 
    Search ThermoFisher Antibodies for SYT15
    Search LSBio for Antibodies for SYT15 

    Assay Products for SYT15: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SYT15
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SYT15
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SYT15 
    Cloud-Clone Corp. CLIAs for SYT15


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SYT: Synaptotagmins

    3 InterPro protein domains:
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR018029 C2_membr_targeting
     IPR000008 C2_Ca-dep

    Graphical View of Domain Structure for InterPro Entry Q9BQS2

    ProtoNet protein and cluster: Q9BQS2

    2 Blocks protein domains:
    IPB000008 C2 domain
    IPB000595 Cyclic nucleotide-binding domain


    UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2
    Domain: Neither C2 domains mediates Ca(2+)-dependent or -independent phospholipid binding (By similarity)
    Similarity: Belongs to the synaptotagmin family
    Similarity: Contains 2 C2 domains


    SYT15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYT15_HUMAN, Q9BQS2
    Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity ----
    GO:0005515protein binding ----
         
    SYT15 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYT15 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SYT15

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYT15 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYT15 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT15
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT15:
    hsa-miR-942 hsa-miR-149 hsa-miR-3138 hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SYT15 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SYT15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT15

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SYT15
    Sirion Biotech Customized adenovirus for overexpression of SYT15

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SYT15 (see all 14)
    OriGene ORF clones in mouse, rat for SYT15
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SYT15 (NM_181519)
    Sino Biological Human cDNA Clone for SYT15
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT15
    Sirion Biotech Customized lentivirus for stable overexpression of SYT15 
                         Customized lentivirus expression plasmids for stable overexpression of SYT15 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SYT15
    Search LifeMap BioReagents cell lines for SYT15
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYT15

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SYT15 (ENSP000003634414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYT15

    Search CenterWatch for drugs/clinical trials and news about SYT15

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYT15 gene (2 alternative transcripts): 
    NM_031912.4  NM_181519.2  

    Unigene Cluster for SYT15:

    Synaptotagmin XV
    Hs.696346  [show with all ESTs]
    Unigene Representative Sequence: NM_031912
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374328 ENST00000449358 ENST00000503753 ENST00000374323(uc001jea.3 uc001jeb.3 uc010qfp.1)
    ENST00000374321 ENST00000512997 ENST00000374325(uc001jdz.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT15
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT15:
    hsa-miR-942 hsa-miR-149 hsa-miR-3138 hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SYT15 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SYT15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT15
    Clone
    Products:
         
    OriGene clones in human, mouse for SYT15 (see all 14)
    OriGene ORF clones in mouse, rat for SYT15
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SYT15 (NM_181519)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT15
    Sirion Biotech Customized lentivirus for stable overexpression of SYT15 
                         Customized lentivirus expression plasmids for stable overexpression of SYT15 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SYT15
    OriGene qSTAR qPCR primer pairs in human, mouse for SYT15
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SYT15
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT15
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15

    Additional mRNA sequence: 

    AB109022.1 AB109023.1 AJ303363.1 AK127436.1 AK128634.1 AK131036.1 AK290186.1 AK293632.1 
    BC139914.1 

    15 DOTS entries:

    DT.91945032  DT.75117030  DT.102825061  DT.101965568  DT.121288878  DT.121289001  DT.92036846  DT.99998900 
    DT.121288873  DT.121288950  DT.302919  DT.121289181  DT.437615  DT.91677843  DT.97801736 

    24/30 AceView cDNA sequences (see all 30):

    CA425176 NM_181519 AJ303363 NM_031912 AK131036 AI685755 BV193985 AI266028 
    AK127436 AB109023 AA776148 AL698054 BV197806 AI971263 AK130877 BV193971 
    AB109022 AK128634 BG546774 AI796878 BX483311 BE549611 AW206939 BG538970 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYT15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SYT15 Expression
    About this image


    See SYT15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYT15

    SOURCE GeneReport for Unigene cluster: Hs.696346
        SABiosciences Custom PCR Arrays for SYT15
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SYT15
    OriGene qSTAR qPCR primer pairs in human, mouse for SYT15
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SYT15
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT15
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SYT15 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syt151 , 5 synaptotagmin XV1, 5 83.25(n)1
    78.95(a)1
      14 (20.80 cM)5
    3195081  NM_181529.41  NP_852682.11 
     342195955 
    chicken
    (Gallus gallus)
    Aves SYT151 synaptotagmin XV 63.4(n)
    62.2(a)
      423614  XM_421499.3  XP_421499.3 
    lizard
    (Anolis carolinensis)
    Reptilia SYT156
    synaptotagmin XV
    57(a)
    1 ↔ 1
    GL343199.1(4002952-4038024)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.90572 Transcribed sequence with weak similarity to protein more 75.65(n)    CF784112.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7980211 synaptotagmin-15-like 54.08(n)
    43.88(a)
      798021  XM_001338439.2  XP_001338475.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sytalpha6
    Synaptotagmin alpha
    18(a)
    1 → many
    2L(17592260-17603640)


    ENSEMBL Gene Tree for SYT15 (if available)
    TreeFam Gene Tree for SYT15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYT15 gene
    SYT132  
    13 SIMAP similar genes for SYT15 using alignment to 3 protein entries:     SYT15_HUMAN (see all proteins):
    SYT10    SYT2    SYT7    SYT9    SYTL4    SYT5
    SYT1    DOC2A    SYTL3    CHR11SYT    PIK3C2A    SYT17
    SYT4

    SYT15 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SYT15
    PGOHUM00000258499


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/463 SNPs in SYT15 are shown (see all 463)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs5283111,2
    C--46954997(-) TGCTGC/ACTTTG 1 -- ds50012Minor allele frequency- A:0.00NA 4
    rs105452411,2
    C--46955005(+) GCAGA-/GTCGTCTT 1 -- ds50010--------
    rs31277701,2
    C,F--46955073(+) GGGCCG/AAGATA 1 -- ds50012Minor allele frequency- A:0.50NA 4
    rs5046951,2
    C--46955251(-) CTGAGT/CGTCTG 1 -- ds50012Minor allele frequency- C:0.00NA 4
    rs5046631,2
    --46955257(-) TTCCAA/GCTGAG 1 -- ds50010--------
    rs5045731,2
    F--46955290(-) TGCCCG/ATCTAT 1 -- ds50012Minor allele frequency- A:0.00NA 4
    rs1890355211,2
    --46955448(+) GTTTCC/GTGGAG 1 -- ut310--------
    rs114995271,2
    C--46955545(+) CAAAAC/TGGAGC 1 -- ut310--------
    rs31204351,2
    C,F--46955632(+) atctaT/Caagaa 1 -- int14Minor allele frequency- C:0.42NA 12
    rs1923463211,2
    --46955770(+) ACTCTA/GAGCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SYT15 (46955444 - 46971400 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/48 variations for SYT15 (see all 48):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2736152CNV Deletion23290073
    nsv436102CNV Deletion17901297
    esv2736163CNV Deletion23290073
    nsv820817CNV Duplication20802225
    dgv662n71CNV Loss21882294
    nsv438171CNV Loss16468122
    esv2750898CNV Loss17911159
    dgv655n71CNV Loss21882294
    nsv895135CNV Loss21882294
    dgv23e55CNV Loss17911159

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SYT15
    DNA2.0 Custom Variant and Variant Library Synthesis for SYT15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608081    OMIM disorders: --

    2 diseases for SYT15:    About MalaCards
    neuronitis    


    SYT15 for disorders           About GeneDecksing


    Export disorders for SYT15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYT15 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SYT15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic analysis of synaptotagmin genes. (PubMed id 11543631)1, 2, 3 Craxton M.A. (2001)
    2. Molecular cloning and characterization of human, rat, and mouse synaptotagmin XV. (PubMed id 12788067)1, 2, 9 Fukuda M. (2003)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Synaptotagmins: why so many? (PubMed id 11739399)1 Sudhof T.C. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83849 HGNC: 17167 AceView: SYT15 Ensembl:ENSG00000204176 euGenes: HUgn83849
    ECgene: SYT15 H-InvDB: SYT15

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYT15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYT15 gene:
    Search GeneIP for patents involving SYT15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SYT15  
     OriGene qPCR primer pairs and template standards for SYT15   OriGene Protein Over-expression Lysate for SYT15  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SYT15  
     OriGene qSTAR qPCR primer pairs in human, mouse for SYT15   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SYT15   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SYT15   OriGene Custom Protein Services for SYT15  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYT15
     QIAGEN SeqTarget long-range PCR primers for resequencing SYT15
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT15
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT15
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT15
     GenScript Custom Purified and Recombinant Proteins Services for SYT15 GenScript cDNA clones with any tag delivered in your preferred vector for SYT15
     GenScript Custom Assay Services for SYT15 GenScript Custom Superior Antibodies Services for SYT15
     GenScript Custom overexpressing Cell Line Services for SYT15 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SYT15 promoter
     Search Chromatin IP Primers for SYT15
     RT2 qPCR Primer Assay in human, mouse, rat SYT15
     Search GNC Networks for SYT15
     SABiosciences Custom PCR Arrays for SYT15
     Search Tocris compounds for SYT15
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for SYT15
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SYT15 lysates
     Search for Antibodies for SYT15 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SYT15
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for SYT15
     Antibodies for SYT15
     ELISAs for SYT15
     CLIAs for SYT15
     Search LifeMap BioReagents cell lines for SYT15
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15
     SwitchGear 3'UTR luciferase reporter plasmids for SYT15
     SwitchGear Promoter luciferase reporter plasmids for SYT15
     Search ThermoFisher Antibodies for SYT15
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT15
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SYT15
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SYT15
    Customized:
     lentivirus for stable overexpression of SYT15
     lentivirus expression plasmids for stable overexpression of SYT15
     adenovirus for overexpression of SYT15
     Search LSBio for Antibodies for SYT15
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SYT15 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4