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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SYT15 Gene

protein-coding GIFtS: 45
GCID: GC10M046955

synaptotagmin XV

Explore 1 disease affiliated with
SYT15 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Synaptotagmin XV¹ ² ³		Synaptotagmin-15¹
CHR10SYT¹ ²		SytXV³
Chr10 Synaptotagmin²		Chr10Syt³
Synaptotagmin XV-A²		SytXV³

External Ids:	HGNC: 17167¹	Entrez Gene: 83849²	Ensembl: ENSG00000204176⁷	OMIM: 608081⁵	UniProtKB: Q9BQS2³

Export aliases for SYT15 gene to outside databases

Previous GC identifers: GC10U900263 GC10M046339 GC10M046378 GC10M042810

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT15:

This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family

contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded

protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct

isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2

Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_031847.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SYT15 gene promoter:
RFX1 USF1 AML1a GATA-2 E2F-1 E2F USF-1 STAT3 c-Myb En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYT15 promoter sequence

Search SABiosciences Chromatin IP Primers for SYT15

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT15

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.1 Ensembl cytogenetic band: 10q11.22 HGNC cytogenetic band: 10q11.1

SYT15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT15 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M046955: view genomic region (about GC identifiers)

Start:	46,955,444 bp from pter	End:	46,971,400 bp from pter
Size:	15,957 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2 (See protein sequence)

Recommended Name: Synaptotagmin-15

Size: 421 amino acids; 47375 Da

Subunit: Homodimer (By similarity)

Subcellular location: Isoform 1: Cell membrane; Single-pass type III membrane protein (By similarity)

Subcellular location: Isoform 2: Cell membrane; Single-pass type III membrane protein (By similarity)

Subcellular location: Isoform 4: Cell membrane; Single-pass type III membrane protein (By similarity)

Secondary accessions: A5D6W8 Q5VY53 Q5VY55 Q7Z439 Q7Z440

Alternative splicing: 4 isoforms: Q9BQS2-1 Q9BQS2-2 Q9BQS2-3 Q9BQS2-4

Explore the universe of human proteins at neXtProt for SYT15: NX_Q9BQS2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BQS2

SYT15 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_114118.2 NP_852660.1

ENSEMBL proteins:

ENSP00000363448 ENSP00000427607 ENSP00000363443 ENSP00000363441 ENSP00000424803

ENSP00000363445

Human Recombinant Protein Products:

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	Uscn Proteins for SYT15

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000299	integral to membrane of membrane fraction	--	--
GO:0005886	plasma membrane	IEA	--
GO:0008021	synaptic vesicle	--	--
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	IEA	--

SYT15 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for SYT15

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SYT15 for domains About GeneDecksing

3 InterPro domains/families:

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry Q9BQS2

ProtoNet protein and cluster: Q9BQS2

2 Blocks protein families:

IPB000008 C2 domain

IPB000595 Cyclic nucleotide-binding domain

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2

Domain: Neither C2 domains mediates Ca(2+)-dependent or -independent phospholipid binding (By similarity)

Similarity: Belongs to the synaptotagmin family

Similarity: Contains 2 C2 domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SYT15_HUMAN, Q9BQS2

Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues (By

similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SYT15 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT15
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT15:
		hsa-miR-942 hsa-miR-149 hsa-miR-3138 hsa-miR-583
		SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SYT15 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT15 (see all 7) OriGene shRNA RFP: SYT15 OriGene siRNA: SYT15
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SYT15

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT15 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT15 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SYT15 (NM_181519)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SYT15
		Search LifeMap BioReagents cell lines for SYT15

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	--	--

SYT15 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SYT15

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for SYT15 (ENSP00000363441⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SYT15
Search CenterWatch for drugs/clinical trials and news about SYT15

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SYT15 gene (2 alternative transcripts):

NM_031912.4 NM_181519.2

Unigene Cluster for SYT15:

Synaptotagmin XV

Hs.696346 [show with all ESTs]

Unigene Representative Sequence: NM_031912

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000374328 ENST00000449358 ENST00000503753 ENST00000374323(uc001jea.3 uc001jeb.3 uc010qfp.1)

ENST00000374321 ENST00000512997 ENST00000374325(uc001jdz.2)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SYT15 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT15
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT15:
		hsa-miR-942 hsa-miR-149 hsa-miR-3138 hsa-miR-583
		SwitchGear 3'UTR luciferase reporter plasmids (see all 2): SYT15 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT15 (see all 7) OriGene shRNA RFP: SYT15 OriGene siRNA: SYT15
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT15

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT15 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT15 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SYT15 (NM_181519)
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT15 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT15
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15

Additional cDNA sequence:

AB109022.1 AB109023.1 AJ303363.1 AK127436.1 AK128634.1 AK131036.1 AK290186.1 AK293632.1

BC139914.1

15 DOTS entries:

DT.91945032 DT.75117030 DT.102825061 DT.101965568 DT.121288878 DT.121289001 DT.92036846 DT.99998900

DT.121288873 DT.121288950 DT.302919 DT.121289181 DT.437615 DT.91677843 DT.97801736

24/30 AceView cDNA sequences (see all 30):

CA425176 AJ303363 NM_031912 NM_181519 AK131036 AL698054 AB109022 AA776148

AB109023 AK128634 BV197806 BV193985 AK130877 AI685755 AI266028 AK127436

BV193971 AI971263 BE549611 BX483311 BG546774 BU160363 BG538970 AI796878

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SYT15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

SYT15 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SYT15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYT15

SOURCE GeneReport for Unigene cluster: Hs.696346

SABiosciences Custom PCR Arrays for SYT15

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT15 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SYT15 gene from 6/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SYT15¹	synaptotagmin XV	63.4(n) 62.2(a)		423614 XM_421499.3 XP_421499.3
lizard (Anolis carolinensis)	Reptilia	SYT15⁶	--	58(a)	1 ↔ 1	GL343199.1(4021987-4038002)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.9057²	Transcribed sequence with weak similarity to protein more	75.65(n)		CF784112.1
zebrafish (Danio rerio)	Actinopterygii	LOC798021¹	synaptotagmin-15-like	54.08(n) 43.88(a)		798021 XM_001338439.2 XP_001338475.1
fruit fly (Drosophila melanogaster)	Insecta	Sytalpha⁶	Synaptotagmin alpha	18(a)	possible ortholog	2L(17592260-17603640)
worm (Caenorhabditis elegans)	Secernentea	snt-6⁶	SyNapTotagmin family member (snt-6)	20(a)	possible ortholog	II(745469-750171)

ENSEMBL Gene Tree for SYT15 (if available)
TreeFam Gene Tree for SYT15 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SYT15 gene

SYT4² SYT5² SYT8² SYT9² SYT3² SYT10² SYT6² SYT17²

SYT11² SYT2² SYT12² SYT7² SYT1²

12 SIMAP similar genes for SYT15 using alignment to 3 protein entries: SYT15_HUMAN (see all proteins):

SYT10 SYT2 SYT7 SYT9 SYTL4 SYT5

SYT1 DOC2A SYTL3 CHR11SYT PIK3C2A SYT17

SYT15 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for SYT15
PGOHUM00000258499

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs528311^1,2	C	--	46954997(-)	`TGCTGC/ACTTTG`	1	--	ds500¹		2		NA	4
rs10545241^1,2	C,	--	46955005(+)	`GCAGA-/GTCGTCTT`	1	--	ds500¹		0	--	--	--	--
rs3127770^1,2	C,F	--	46955073(+)	`GGGCCG/AAGATA`	1	--	ds500¹		2		NA	4
rs504695^1,2	C,	--	46955251(-)	`CTGAGT/CGTCTG`	1	--	ds500¹		2		NA	4
rs504663^1,2		--	46955257(-)	`TTCCAA/GCTGAG`	1	--	ds500¹		0	--	--	--	--
rs504573^1,2		--	46955290(-)	`TGCCCG/ATCTAT`	1	--	ds500¹		2		NA	4
rs189035521^1,2		--	46955448(+)	`GTTTCC/GTGGAG`	1	--	ut3¹		0	--	--	--	--
rs3120435^1,2	C,F	--	46955632(+)	`ATCTAT/CAAGAA`	1	--	int¹		4		NA	12
rs192346321^1,2		--	46955770(+)	`ACTCTA/GAGCTG`	1	--	int¹		0	--	--	--	--
rs3127772^1,2	C,H,	--	46955833(+)	`TGGGAA/GGTGGT`	1	--	int¹		10		NS EA NA WA CSA	433

HapMap Linkage Disequilibrium report for SYT15 (46955444 - 46971400 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 24 variations for SYT15
15/24 CNVs (see all 24): 34603 9150 8652 48536 3798 8647 65654 8646 34572 34600 34456 48538 4682 48539 4683

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT15

DNA2.0 Custom Variant and Variant Library Synthesis for SYT15

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SYT15 for disorders           About GeneDecksing

OMIM gene information: 608081    OMIM disorders: --

1 disease for SYT15:    About MalaCards

neuronitis

Export disorders for SYT15 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SYT15 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SYT15)

Utopia: connect your pdf to the dynamic
world of online information

Genomic analysis of synaptotagmin genes. (PubMed id 11543631)^{1, 2, 3} Craxton M.A. (2001)
Molecular cloning and characterization of human, rat, and mouse synaptotagmin XV. (PubMed id 12788067)^{1, 2, 9} Fukuda M. (2003)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)² Deloukas P.... Rogers J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Synaptotagmins: why so many? (PubMed id 11739399)¹ Sudhof T.C. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 83849	HGNC: 17167	AceView: SYT15	Ensembl:ENSG00000204176	euGenes: HUgn83849
ECgene: SYT15	H-InvDB: SYT15

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SYT15	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SYT15 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SYT15 gene:
Search GeneIP for patents involving SYT15

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for SYT15
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT15		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT15
	OriGene Protein Over-expression Lysate for SYT15		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SYT15		OriGene 3'-UTR Clone for SYT15
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	OriGene Custom Antibody Services for SYT15		OriGene Custom Protein Services for SYT15
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYT15
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT15
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT15
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT15
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT15
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT15

	GenScript Custom Purified and Recombinant Proteins Services for SYT15		GenScript cDNA clones with any tag delivered in your preferred vector for SYT15
	GenScript Custom Assay Services for SYT15		GenScript Custom Superior Antibodies Services for SYT15
	GenScript Custom overexpressing Cell Line Services for SYT15		CloneReady with Over 120,000 Genes
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	Regulatory tfbs in SYT15 promoter
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SYT15 Proteins, Antibodies, CLIAs, and ELISAs

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT15

	SwitchGear 3'UTR luciferase reporter plasmids for SYT15
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT15

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SYT15 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

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Export list of displayed genes

SYT15 Gene

synaptotagmin XV

Aliases
for SYT15 gene

Summaries
for SYT15 gene

Genomic Views
for SYT15 gene

Proteins
for SYT15 gene

Protein Domains /
Families
for SYT15 gene

Function
for SYT15 gene

Pathways & Interactions
for SYT15 gene

Drugs & Compounds
for SYT15 gene

Transcripts
for SYT15 gene

Expression
for SYT15 gene

Orthologs
for SYT15 gene

Paralogs
for SYT15 gene

Genomic Variants
for SYT15 gene

Disorders / Diseases
for SYT15 gene

Publications
for SYT15 gene

External Searches for SYT15 gene

Genome Databases showing SYT15 gene

Other Databases showing SYT15 gene

Specialized Databases showing SYT15 gene

Intellectual Property
for SYT15 gene

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Export list of displayed genes

SYT15 Gene

synaptotagmin XV

Aliasesfor SYT15 gene

Summariesfor SYT15 gene

Genomic Viewsfor SYT15 gene

Proteinsfor SYT15 gene

Protein Domains /Familiesfor SYT15 gene

Functionfor SYT15 gene

Pathways & Interactionsfor SYT15 gene

Drugs & Compoundsfor SYT15 gene

Transcriptsfor SYT15 gene

Expression for SYT15 gene

Orthologsfor SYT15 gene

Paralogsfor SYT15 gene

Genomic Variantsfor SYT15 gene

Disorders / Diseasesfor SYT15 gene

Publicationsfor SYT15 gene

External Searches for SYT15 gene

Genome Databases showing SYT15 gene

Other Databases showing SYT15 gene

Specialized Databases showing SYT15 gene

Intellectual Propertyfor SYT15 gene

Productsfor SYT15 gene

View Random Gene

Aliases
for SYT15 gene

Summaries
for SYT15 gene

Genomic Views
for SYT15 gene

Proteins
for SYT15 gene

Protein Domains /
Families
for SYT15 gene

Function
for SYT15 gene

Pathways & Interactions
for SYT15 gene

Drugs & Compounds
for SYT15 gene

Transcripts
for SYT15 gene

Expression
for SYT15 gene

Orthologs
for SYT15 gene

Paralogs
for SYT15 gene

Genomic Variants
for SYT15 gene

Disorders / Diseases
for SYT15 gene

Publications
for SYT15 gene

Intellectual Property
for SYT15 gene

Products
for SYT15 gene