SYT14L Gene
pseudogene GIFtS: 30
GCID: GC04M068926
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synaptotagmin XIV-like
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Aliases
for SYT14L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Synaptotagmin XIV-Like1 2 | | SYTDEP1 2 3 5 | | CHR415SYT1 2 5 | | Synaptotagmin XIV-Derived Protein3 | | Synaptotagmin XIV-Like Protein3 |
| External Ids: | HGNC: 334291 | Entrez Gene: 4011352 | Ensembl: ENSG000002151277 | OMIM: 6108925 | UniProtKB: Q58G823 |
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| | ORGUL members: | |
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| NONCODE:n386358 | |
Export aliases for SYT14L gene to outside databasesPrevious GC identifers: GC14P060536 GC14P060452 GC14P061532 GC04M068611 GC04M064842
Summaries
for SYT14L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for SYT14L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_022778.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SYT14L gene promoter:
Nkx3-1 RP58 Nkx3-1 v4 Nkx3-1 v1 Nkx2-5 C/EBPalpha Nkx3-1 v2 IRF-7A Nkx3-1 v3 TGIF
Other transcription factors
Search SABiosciences Chromatin IP Primers for SYT14L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT14L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q13.2 Ensembl cytogenetic band: 4q13.2 HGNC cytogenetic band: 4q13.2SYT14L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M068926: view genomic region
(about GC identifiers)
Start:
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68,926,312 bp from pter |
End:
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68,929,015 bp from pter |
Size:
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2,704 bases |
Orientation:
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minus strand |
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Proteins
for SYT14L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: SY14L_HUMAN, Q58G82 (See
protein sequence)Recommended Name: Putative synaptotagmin-14-like protein Size: 188 amino acids; 21436 Da
Developmental stage: Up-regulated during neutrophil differentiation
Caution: Could be the product of a pseudogene. Encoded by an expressed retrotransposed copy of the SYT14 locus into anintron of TMPRSS11F. PubMed:16376304, detected a 27 kDa protein in human neutrophils that might be the product of thatgene
Secondary accessions: A2RTZ8 Q9BQR7Explore the universe of human proteins at neXtProt for SYT14L: NX_Q58G82
SYT14L Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
SYT14L Antibody Products:
Assay Products for SYT14L: |
Protein
Domains /
Families
for SYT14L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SYT14L for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q58G82ProtoNet protein and cluster: Q58G82 1 Blocks protein family: IPB000008 C2 domain
UniProtKB/Swiss-Prot: SY14L_HUMAN, Q58G82Similarity: Belongs to the synaptotagmin familySimilarity: Contains 1 C2 domain |
Function
for SYT14L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for SYT14L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SYT14L
|
Drugs & Compounds
for SYT14L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SYT14L
Search CenterWatch for drugs/clinical trials and news about SYT14L 
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Transcripts
for SYT14L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for SYT14L gene: NM_001014372.3 Unigene Clusters for SYT14L: Synaptotagmin XIV-like Hs.130270 [show with all ESTs], Hs.712109 Unigene Representative Sequences: BC041902, NR_0270942 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000481459(uc021xou.1) ENST00000419424(uc010ihn.3)
Additional cDNA sequence: AY954513.2 NR_027094.1 4 DOTS entries: DT.91812248 DT.95245199 DT.121222447 DT.121222484 24/82 AceView cDNA sequences (see all 82): BM021119 BQ575474 BC043376 CA312638 CF890926 CK820329 BU528383 AK129519 BQ690164 BI756743 BQ000556 AK093682 CA420787 CF887245 CF132053 BU174592 CB105047 CF890925 AA844424 CR623293 BG171079 BE886090 CK820330 BM919725
GeneLoc Exon Structure
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Expression
for SYT14L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SYT14L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAAAGCTGA
About this image
SOURCE GeneReport for Unigene clusters: Hs.130270 Hs.712109
UniProtKB/Swiss-Prot: SY14L_HUMAN, Q58G82Tissue specificity: Highly expressed in mature peripheral blood neutrophils
SABiosciences Custom PCR Arrays for SYT14L
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT14L
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SYT14L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT14L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT14L |
Orthologs
for SYT14L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for SYT14L (if available)
TreeFam Gene Tree for SYT14L (if available) |
Paralogs
for SYT14L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for SYT14L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for SYT14L
9 CNVs: 8448 37549 31175 2523 3498 9483 2072 80348 63851 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for SYT14L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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 SYT14L for disorders About MalaCards
SYT14L for disorders About GeneDecksing
OMIM gene information: 610892
OMIM disorders: --
Export disorders for SYT14L gene to outside databases
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Publications
for SYT14L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for SYT14L gene integrated from 9 sources:
(articles sorted by number of sources associating them with SYT14L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and genomic characterization of sytdep, a new synaptotagmin XIV-related gene. (PubMed id 16376304)1, 2, 3, 9 Herrero-Turrion M.J.... Mollinedo F. (2006)
- Genomic analysis of synaptotagmin genes. (PubMed id 11543631)1, 2 Craxton M.A. (2001)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Synaptotagmin gene content of the sequenced genomes. (PubMed id 15238157)1 Craxton M.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for SYT14L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SYT14L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing SYT14L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SYT14L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for SYT14L gene:
Search GeneIP for patents involving SYT14L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SYT14L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SYT14L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT14L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT14L | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SYT14L | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT14L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SYT14L | | OriGene Custom Protein Services for SYT14L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYT14L | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT14L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT14L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT14L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT14L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT14L |
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| | | | Search Tocris compounds for SYT14L |
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 | | | SYT14L Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for SYT14L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SYT14L |
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Last full update: 18 Mar 2013 -
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