Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SYT13 Gene

protein-coding GIFtS: 51
GCID: GC11M045261

synaptotagmin XIII

Search for SYT13
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Synaptotagmin XIII¹ ² ³
KIAA1427¹ ³ ⁵
Synaptotagmin-13¹
SytXIII³
SytXIII³

External Ids:	HGNC: 14962¹	Entrez Gene: 57586²	Ensembl: ENSG00000019505⁷	OMIM: 607716⁵	UniProtKB: Q7L8C5³

Export aliases for SYT13 gene to outside databases

Previous GC identifers: GC11M047006 GC11P045773 GC11M045293 GC11M045226 GC11M045218 GC11M044971

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SYT13:

This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal

transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family

members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and

developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in

multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have

been described for this gene. (provided by RefSeq, Oct 2011)

UniProtKB/Swiss-Prot: SYT13_HUMAN, Q7L8C5

Function: May be involved in transport vesicle docking to the plasma membrane (By similarity)

Gene Wiki entry for SYT13

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SYT13 gene promoter:
c-Fos Max1 AP-1 LUN-1 Evi-1 GATA-1 Max HOXA5 Pax-4a c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYT13 promoter sequence

Search SABiosciences Chromatin IP Primers for SYT13

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT13

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p12-p11 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p12-p11

SYT13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYT13 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M045261: view genomic region (about GC identifiers)

Start:	45,261,852 bp from pter	End:	45,307,884 bp from pter
Size:	46,033 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYT13_HUMAN, Q7L8C5 (See protein sequence)

Recommended Name: Synaptotagmin-13

Size: 426 amino acids; 46885 Da

Subunit: Interacts with NRXN1 (By similarity)

Subcellular location: Membrane; Single-pass membrane protein (By similarity)

Sequence caution: Sequence=BAA92665.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for SYT13:

1WFM (3D)

Secondary accessions: A8K4P4 D3DQP1 Q9BQS3 Q9H041 Q9P2C0

Explore the universe of human proteins at neXtProt for SYT13: NX_Q7L8C5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q7L8C5

SYT13 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001234916.1 NP_065877.1

ENSEMBL proteins:

ENSP00000020926 ENSP00000434967 ENSP00000432975

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SYT13 OriGene Protein Over-expression Lysate: SYT13 OriGene Custom Protein Services for SYT13
	GenScript Custom Purified and Recombinant Proteins Services for SYT13
	Novus Biologicals SYT13 Protein Novus Biologicals SYT13 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SYT13

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	IEA	--
GO:0030133	transport vesicle	IDA	--

SYT13 for ontologies About GeneDecksing

SYT13 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for SYT13
	GenScript Custom Superior Antibodies Services for SYT13
	Novus Biologicals SYT13 Antibodies
	Search for Antibodies for SYT13 at Abcam
	Uscn Antibodies for SYT13
	ThermoFisher Antibodies for SYT13

Assay Products for SYT13:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SYT13
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SYT13

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SYT13 for domains About GeneDecksing

3 InterPro domains/families:

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry Q7L8C5

ProtoNet protein and cluster: Q7L8C5

1 Blocks protein family: IPB000008 C2 domain

UniProtKB/Swiss-Prot: SYT13_HUMAN, Q7L8C5

Domain: The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding (By similarity)

Domain: The second C2 domain/C2B domain binds phospholipids regardless of whether calcium is present (By similarity)

Similarity: Belongs to the synaptotagmin family

Similarity: Contains 2 C2 domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SYT13_HUMAN, Q7L8C5

Function: May be involved in transport vesicle docking to the plasma membrane (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: SYT13 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT13
		8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT13 (see all 34):
		hsa-miR-1321 hsa-miR-640 hsa-miR-3616-5p hsa-miR-1224-3p hsa-miR-218 hsa-miR-650 hsa-miR-10b* hsa-miR-649

		SwitchGear 3'UTR luciferase reporter plasmid: SYT13 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT13 (see all 6) OriGene siRNA: SYT13
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT13

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SYT13

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SYT13 (NM_020826)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT13
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT13

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SYT13
		Search LifeMap BioReagents cell lines for SYT13

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT13

1 GenomeRNAi human phenotype for SYT13:

Decreased viability with pacli

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SYT13

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for SYT13 (Q7L8C5³ ENSP00000020926⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NRXN1	Q9ULB1³, ENSP00000385142⁴	I2D: score=2 STRING: ENSP00000385142

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016192	vesicle-mediated transport	IEA	--

SYT13 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SYT13

1 HMDB Compound for SYT13 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about SYT13

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SYT13 gene (2 alternative transcripts):

NM_001247987.1 NM_020826.2

Unigene Cluster for SYT13:

Synaptotagmin XIII

Hs.436643 [show with all ESTs]

Unigene Representative Sequence: NM_001247987

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000020926(uc009yku.1 uc001myq.2) ENST00000533332 ENST00000528101

miRNA Products:		OriGene 3'-UTR Clone: SYT13 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYT13
		8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate SYT13 (see all 34):
		hsa-miR-1321 hsa-miR-640 hsa-miR-3616-5p hsa-miR-1224-3p hsa-miR-218 hsa-miR-650 hsa-miR-10b* hsa-miR-649

		SwitchGear 3'UTR luciferase reporter plasmid: SYT13 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT13 (see all 6) OriGene siRNA: SYT13
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT13

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SYT13 (NM_020826)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYT13
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT13

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT13 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYT13
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT13
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT13

Additional cDNA sequence:

AB037848.1 AJ303362.1 AK291009.1 AK308841.1 AL512743.1 BC093830.1 BC093832.1

3 DOTS entries:

DT.95165324 DT.92420257 DT.95301934

24/90 AceView cDNA sequences (see all 90):

CK818813 CR592126 CA423496 BM839692 BE671015 AJ303362 AI267908 AA928902

BM829236 BX432020 F10796 AL564852 BM127079 BM759461 AW023391 AW069785

BI522800 W40314 BM709820 AA514387 AA211209 AW770696 AL138279 BX433395

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for SYT13 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9
SP1:					-		-		-
SP2:					-
SP3:							-		-

ECgene alternative splicing isoforms for SYT13

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SYT13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGACATTGTA

About this image

SYT13 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Sclerotome cells (Primary Cell)

Bone, Cartilage, Somite

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SYT13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYT13

SOURCE GeneReport for Unigene cluster: Hs.436643

UniProtKB/Swiss-Prot: SYT13_HUMAN, Q7L8C5

Tissue specificity: Expressed in brain, pancreas and kidney

SABiosciences Custom PCR Arrays for SYT13

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT13 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYT13
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT13
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT13

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT13

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SYT13 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SYT13⁶	Uncharacterized protein	67(a)	1 ↔ 1	5(24411106-24423434)
lizard (Anolis carolinensis)	Reptilia	SYT13⁶	--	68(a)	1 ↔ 1	1(46870288-46886879)
zebrafish (Danio rerio)	Actinopterygii	Dr.17253²	Transcribed sequence with weak similarity to protein more	77.82(n)		BM023677.1
fruit fly (Drosophila melanogaster)	Insecta	Sytalpha⁶	Synaptotagmin alpha	16(a)	possible ortholog	2L(17592260-17603640)
worm (Caenorhabditis elegans)	Secernentea	snt-6⁶ snt-7⁶	Protein SNT-7	20(a) 14(a)	possible ortholog 1 ↔ 1	II(745469-750171) X(15195833-15199067)

ENSEMBL Gene Tree for SYT13 (if available)
TreeFam Gene Tree for SYT13 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116000887^1,2	F,	--	45261360(+)	`TCACAC/TAAGCG`	2	--	int¹		1		WA	118
rs58711889^1,2	C	--	45261415(+)	`ACAGT-/AAAAAA`	2	--	int¹		2		NA CSA	4
rs193207630^1,2		--	45261446(+)	`ATGTAA/GATATA`	2	--	int¹		0	--	--	--	--
rs139348138^1,2		--	45261459(+)	`TCAACC/TGCATA`	2	--	int¹		0	--	--	--	--
rs184572266^1,2		--	45261500(+)	`CATACA/GTCAGT`	2	--	int¹		0	--	--	--	--
rs57610243^1,2		--	45261523(+)	`AACTGC/GAGCTG`	2	--	int¹		0	--	--	--	--
rs189237182^1,2		--	45261609(+)	`AAAACA/CCTTTA`	2	--	int¹		0	--	--	--	--
rs145041027^1,2		--	45261824(+)	`TAAAAC/TGGAAA`	2	--	int¹		0	--	--	--	--
rs149113991^1,2		--	45261855(+)	`TGACCC/TTGTTG`	2	--	ut3¹		0	--	--	--	--
rs143009829^1,2		--	45261857(+)	`ACCCTA/GTTGGA`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SYT13 (45261852 - 45307884 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SYT13: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT13

DNA2.0 Custom Variant and Variant Library Synthesis for SYT13

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SYT13 for disorders About MalaCards

SYT13 for disorders About GeneDecksing

OMIM gene information: 607716 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: SYT13 (1 document)

Export disorders for SYT13 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SYT13 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SYT13)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII). (PubMed id 11171101)^{1, 3, 9} Fukuda M. and Mikoshiba K. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Genomic analysis of synaptotagmin genes. (PubMed id 11543631)^{1, 2} Craxton M.A. (2001)
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)^{1, 2} Nagase T.... Ohara O. (2000)
Re-expression of tumorigenicity after attenuation of human synaptotagmin 13 in a suppressed microcell hybrid cell line. (PubMed id 18202767)^{1, 9} Jahn J.E. and Coleman W.B. (2008)
The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)¹ Lin C.W....Jan M.S. (2012)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Exogenous expression of synaptotagmin XIII suppresses the neoplastic phenotype of a rat liver tumor cell line through molecular path ways related to mesenchymal to epithelial transition. (PubMed id 20840848)¹ Jahn J.E....Coleman W.B. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The LIFEdb database in 2006. (PubMed id 16381901)¹ Mehrle A....Wiemann S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57586	HGNC: 14962	AceView: SYT13	Ensembl:ENSG00000019505	euGenes: HUgn57586
ECgene: SYT13	H-InvDB: SYT13

(According to HUGE)
About This Section

HUGE: KIAA1427

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SYT13	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SYT13 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SYT13 gene:
Search GeneIP for patents involving SYT13

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYT13		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYT13
	OriGene Protein Over-expression Lysate for SYT13		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SYT13		OriGene 3'-UTR Clone for SYT13
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYT13
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for SYT13		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SYT13		OriGene Custom Protein Services for SYT13
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYT13
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYT13
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYT13
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYT13
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYT13
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYT13

	GenScript Custom Purified and Recombinant Proteins Services for SYT13		GenScript cDNA clones with any tag delivered in your preferred vector for SYT13
	GenScript Custom Assay Services for SYT13		GenScript Custom Superior Antibodies Services for SYT13
	GenScript Custom overexpressing Cell Line Services for SYT13		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in SYT13 promoter
	Search Chromatin IP Primers for SYT13
	RT² qPCR Primer Assay in human, mouse, rat SYT13
	Search GNC Networks for SYT13
	SABiosciences Custom PCR Arrays for SYT13

Search Tocris compounds for SYT13

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	SYT13 antibodies
	SYT13 proteins
	SYT13 lysates

	Search for Antibodies for SYT13 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for SYT13
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

SYT13 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for SYT13

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYT13

	SwitchGear 3'UTR luciferase reporter plasmids for SYT13
	SwitchGear Promoter luciferase reporter plasmids for SYT13

ThermoFisher Antibodies for SYT13

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYT13

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SYT13 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

SYT13 Gene

synaptotagmin XIII

Aliases
for SYT13 gene

Summaries
for SYT13 gene

Genomic Views
for SYT13 gene

Proteins
for SYT13 gene

Protein Domains /
Families
for SYT13 gene

Function
for SYT13 gene

Pathways & Interactions
for SYT13 gene

Drugs & Compounds
for SYT13 gene

Transcripts
for SYT13 gene

Expression
for SYT13 gene

Orthologs
for SYT13 gene

Paralogs
for SYT13 gene

Genomic Variants
for SYT13 gene

Disorders / Diseases
for SYT13 gene

Publications
for SYT13 gene

External Searches for SYT13 gene

Genome Databases showing SYT13 gene

Other Databases showing SYT13 gene

Specialized Databases showing SYT13 gene

Intellectual Property
for SYT13 gene

Products
for SYT13 gene

View Random Gene

Advanced Search

Export list of displayed genes

SYT13 Gene

synaptotagmin XIII

Aliasesfor SYT13 gene

Summariesfor SYT13 gene

Genomic Viewsfor SYT13 gene

Proteinsfor SYT13 gene

Protein Domains /Familiesfor SYT13 gene

Functionfor SYT13 gene

Pathways & Interactionsfor SYT13 gene

Drugs & Compoundsfor SYT13 gene

Transcriptsfor SYT13 gene

Expression for SYT13 gene

Orthologsfor SYT13 gene

Paralogsfor SYT13 gene

Genomic Variantsfor SYT13 gene

Disorders / Diseasesfor SYT13 gene

Publicationsfor SYT13 gene

External Searches for SYT13 gene

Genome Databases showing SYT13 gene

Other Databases showing SYT13 gene

Specialized Databases showing SYT13 gene

Intellectual Propertyfor SYT13 gene

Productsfor SYT13 gene

View Random Gene

Aliases
for SYT13 gene

Summaries
for SYT13 gene

Genomic Views
for SYT13 gene

Proteins
for SYT13 gene

Protein Domains /
Families
for SYT13 gene

Function
for SYT13 gene

Pathways & Interactions
for SYT13 gene

Drugs & Compounds
for SYT13 gene

Transcripts
for SYT13 gene

Expression
for SYT13 gene

Orthologs
for SYT13 gene

Paralogs
for SYT13 gene

Genomic Variants
for SYT13 gene

Disorders / Diseases
for SYT13 gene

Publications
for SYT13 gene

Intellectual Property
for SYT13 gene

Products
for SYT13 gene