Aliases for SYT11 Gene
External Ids for SYT11 Gene
Previous GeneCards Identifiers for SYT11 Gene
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
GeneCards Summary for SYT11 Gene
SYT11 (Synaptotagmin 11) is a Protein Coding gene. Among its related pathways are Parkinsons Disease Pathway and Chks in Checkpoint Regulation. GO annotations related to this gene include calcium ion binding and syntaxin binding. An important paralog of this gene is SYT4.
UniProtKB/Swiss-Prot for SYT11 Gene
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.