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Aliases for SYS1-DBNDD2 Gene

Subcategory (RNA class) for SYS1-DBNDD2 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for SYS1-DBNDD2 Gene

  • SYS1-DBNDD2 Readthrough (NMD Candidate) 2 3 5
  • SYS1-DBNDD2 Readthrough (Non-Protein Coding) 2 3
  • C20orf169-DBNDD2 3

External Ids for SYS1-DBNDD2 Gene

Previous GeneCards Identifiers for SYS1-DBNDD2 Gene

  • GC20U900295
  • GC20P043427
  • GC20P043991

Summaries for SYS1-DBNDD2 Gene

Entrez Gene Summary for SYS1-DBNDD2 Gene

  • This locus represents naturally occurring read-through transcription from the neighboring SYS1 Golgi-localized integral membrane protein homolog and dysbindin domain containing 2 (DBNDD2) genes. The read-through transcript includes the majority of exons from each individual gene, but it would be subject to nonsense-mediated mRNA decay (NMD) and is therefore predicted to be non-coding. [provided by RefSeq, Oct 2010]

GeneCards Summary for SYS1-DBNDD2 Gene

SYS1-DBNDD2 (SYS1-DBNDD2 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is SYS1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SYS1-DBNDD2 Gene

Genomics for SYS1-DBNDD2 Gene

Regulatory Elements for SYS1-DBNDD2 Gene

Enhancers for SYS1-DBNDD2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F045334 1.2 FANTOM5 Ensembl ENCODE 12.4 -21.1 -21089 14.4 MLX ZFP64 DMAP1 YY1 ZNF143 SP3 NFYC SSRP1 GLIS1 RCOR2 NCOA5 PCIF1 ZNF335 CD40 ZSWIM1 ENSG00000271984 ENSG00000233352 LOC105372630 ENSG00000237464 RPL5P2
GH20F045426 0.2 ENCODE 11.8 +64.2 64205 1.4 HDAC1 ATF1 PKNOX1 CREB3L1 RAD21 GATA2 ETV6 EGR2 SMARCA5 CEBPB DBNDD2 SYS1-DBNDD2 SYS1 LOC105372631 GC20P045440
GH20F045436 1.1 Ensembl ENCODE 11.7 +73.8 73847 1.2 HDGF WRNIP1 SIN3A ARID4B ZNF48 ZNF2 SLC30A9 GLIS2 ZNF143 KLF7 SYS1-DBNDD2 SYS1 PIGT GC20P045440 LOC105372631
GH20F045432 1.6 FANTOM5 Ensembl ENCODE 11.7 +69.8 69784 1.9 PKNOX1 ZFP64 ZNF140 MAX ZNF384 RELA ZNF316 CBX5 SCRT2 EED NCOA5 DBNDD2 SYS1-DBNDD2 SYS1 ZNF335 WFDC11 KCNS1 WFDC6 GC20P045440 LOC105372631
GH20F045322 0.5 Ensembl ENCODE 11.4 -39.6 -39577 1.6 ATF1 PKNOX1 CREB3L1 ARID4B SIN3A ZNF48 YY1 ZNF143 SP5 NFYC SYS1 SYS1-DBNDD2 PIGT ENSG00000237464 RNU6ATAC38P DNTTIP1 WFDC3 PABPC1L TRV-CAC14-1 ENSG00000275894
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SYS1-DBNDD2 on UCSC Golden Path with GeneCards custom track

Promoters for SYS1-DBNDD2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001449128 31 1601 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1

Genomic Location for SYS1-DBNDD2 Gene

Chromosome:
20
Start:
45,363,169 bp from pter
End:
45,410,610 bp from pter
Size:
47,442 bases
Orientation:
Plus strand

Genomic View for SYS1-DBNDD2 Gene

Genes around SYS1-DBNDD2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SYS1-DBNDD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SYS1-DBNDD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SYS1-DBNDD2 Gene

Proteins for SYS1-DBNDD2 Gene

  • Protein details for SYS1-DBNDD2 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F2Z2A3
    Recommended name:
    Protein SYS1-DBNDD2
    Protein Accession:
    F2Z2A3

    Protein attributes for SYS1-DBNDD2 Gene

    Size:
    78 amino acids
    Molecular mass:
    8717 Da
    Quaternary structure:
    No Data Available
  • Protein details for SYS1-DBNDD2 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BUS1
    Recommended name:
    Protein SYS1-DBNDD2
    Protein Accession:
    H3BUS1

    Protein attributes for SYS1-DBNDD2 Gene

    Size:
    97 amino acids
    Molecular mass:
    11030 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SYS1-DBNDD2 Gene

Post-translational modifications for SYS1-DBNDD2 Gene

No Post-translational modifications

Other Protein References for SYS1-DBNDD2 Gene

No data available for DME Specific Peptides for SYS1-DBNDD2 Gene

Domains & Families for SYS1-DBNDD2 Gene

Protein Domains for SYS1-DBNDD2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SYS1-DBNDD2: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SYS1-DBNDD2 Gene

Function for SYS1-DBNDD2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SYS1-DBNDD2 Gene

Localization for SYS1-DBNDD2 Gene

Gene Ontology (GO) - Cellular Components for SYS1-DBNDD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005802 trans-Golgi network IBA --
GO:0005829 cytosol IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030173 integral component of Golgi membrane IBA --
genes like me logo Genes that share ontologies with SYS1-DBNDD2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for SYS1-DBNDD2 Gene

Pathways & Interactions for SYS1-DBNDD2 Gene

SuperPathways for SYS1-DBNDD2 Gene

No Data Available

Interacting Proteins for SYS1-DBNDD2 Gene

Gene Ontology (GO) - Biological Process for SYS1-DBNDD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006895 Golgi to endosome transport IBA --
GO:0043001 Golgi to plasma membrane protein transport IBA --
genes like me logo Genes that share ontologies with SYS1-DBNDD2: view

No data available for Pathways by source and SIGNOR curated interactions for SYS1-DBNDD2 Gene

Transcripts for SYS1-DBNDD2 Gene

mRNA/cDNA for SYS1-DBNDD2 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SYS1-DBNDD2 Gene

No ASD Table

Relevant External Links for SYS1-DBNDD2 Gene

GeneLoc Exon Structure for
SYS1-DBNDD2
ECgene alternative splicing isoforms for
SYS1-DBNDD2

Expression for SYS1-DBNDD2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SYS1-DBNDD2 Gene

Protein differential expression in normal tissues from HIPED for SYS1-DBNDD2 Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for SYS1-DBNDD2 Gene



Protein tissue co-expression partners for SYS1-DBNDD2 Gene

genes like me logo Genes that share expression patterns with SYS1-DBNDD2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SYS1-DBNDD2 Gene

Orthologs for SYS1-DBNDD2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SYS1-DBNDD2 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm20458 35
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 46 (a)
ManyToMany
-- 35
  • 21 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SYS1 35
  • 36 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 42 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii sys1 35
  • 39 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG11753 35
  • 20 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T03F1.12 35
  • 14 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 25 (a)
OneToMany
Species where no ortholog for SYS1-DBNDD2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SYS1-DBNDD2 Gene

ENSEMBL:
Gene Tree for SYS1-DBNDD2 (if available)
TreeFam:
Gene Tree for SYS1-DBNDD2 (if available)

Paralogs for SYS1-DBNDD2 Gene

Paralogs for SYS1-DBNDD2 Gene

(1) SIMAP similar genes for SYS1-DBNDD2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SYS1-DBNDD2: view

Variants for SYS1-DBNDD2 Gene

Sequence variations from dbSNP and Humsavar for SYS1-DBNDD2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1043974 -- 45,410,462(+) GTCTT(C/T)TAATA nc-transcript-variant, utr-variant-3-prime
rs1046612 -- 45,367,549(+) TTGCA(A/G)TGTTG intron-variant, utr-variant-3-prime
rs10546815 -- 45,375,516(+) TCTTC(-/ATT)ATTTT intron-variant, cds-indel
rs10552564 -- 45,395,598(+) TTTCC(-/TT)TTTTT intron-variant
rs1060891 -- 45,367,399(+) GAGCC(A/C)CAATA intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SYS1-DBNDD2 Gene

Variant ID Type Subtype PubMed ID
dgv4319n100 CNV gain 25217958
nsv1056102 CNV loss 25217958

Relevant External Links for SYS1-DBNDD2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SYS1-DBNDD2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SYS1-DBNDD2 Gene

Disorders for SYS1-DBNDD2 Gene

Relevant External Links for SYS1-DBNDD2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SYS1-DBNDD2

No disorders were found for SYS1-DBNDD2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SYS1-DBNDD2 Gene

Publications for SYS1-DBNDD2 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for SYS1-DBNDD2 Gene

Sources for SYS1-DBNDD2 Gene

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