SYP Gene
protein-coding GIFtS: 64
GCID: GC0XM049044
|
|
synaptophysin
| |
Aliases
for SYP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Synaptophysin1 | | Major Synaptic Vesicle Protein P382 3 | | MRXSYP2 | | MRX5 |
Export aliases for SYP gene to outside databasesPrevious GC identifers: GC0XM047830 GC0XM047286 GC0XM047850 GC0XM048070 GC0XM048800 GC0XM048931 GC0XM046701 |
Summaries
for SYP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SYP:
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The proteinalso binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) tointracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). (providedby RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247Function: Possibly involved in structural functions as organizing other membrane components or in targeting thevesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (Bysimilarity)
Gene Wiki entry for SYP (Synaptophysin)
|
Genomic Views
for SYP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_079573.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SYP gene promoter:
c-Fos COUP-TF1 AP-1 ATF-2 COUP HNF-4alpha2 HNF-4alpha1 COUP-TF c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for SYP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.23-p11.22 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23-p11.22SYP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM049044: view genomic region
(about GC identifiers)
Start:
|
49,044,265 bp from pter |
End:
|
49,056,718 bp from pter |
Size:
|
12,454 bases |
Orientation:
|
minus strand |
|
Proteins
for SYP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247 (See
protein sequence)Recommended Name: Synaptophysin Size: 313 amino acids; 33845 Da
Subunit: Homohexamer or homotetramer. Interacts with SRCIN1
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.Cell junction, synapse, synaptosome
Secondary accessions: B2R7L6 Q6P2F7Explore the universe of human proteins at neXtProt for SYP: NX_P08247
Post-translational modifications:
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P08247
SYP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003170.1
ENSEMBL proteins: ENSP00000263233 ENSP00000418387 ENSP00000365480 ENSP00000418169 ENSP00000418987 ENSP00000420774 ENSP00000437456
Human Recombinant Protein Products:
Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15): About this table
SYP for ontologies About GeneDecksing
SYP Antibody Products:  | EMD Millipore Mono- and Polyclonal Antibodies for the study of SYP |  | R&D Systems Antibodies for SYP (Synaptophysin) |  | Cell Signaling Technology (CST) Antibodies for SYP |  | OriGene Antibodies (see all 8): SYP
OriGene Custom Antibody Services for SYP 
|  | GenScript Superior Antibodies for SYP |  | Novus Biologicals SYP Antibodies |  | Abcam antibodies for SYP |  | Uscn Antibodies for SYP |  | ThermoFisher Antibody for SYP |
Assay Products for SYP: |
Protein
Domains /
Families
for SYP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SYP for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P08247ProtoNet protein and cluster: P08247 2 Blocks protein families: IPB001285 Synaptophysin/synaptoporin IPB008253 Marvel
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247Domain: The calcium-binding activity is thought to be localized in the cytoplasmic tail of the proteinSimilarity: Belongs to the synaptophysin/synaptobrevin familySimilarity: Contains 1 MARVEL domain |
Function
for SYP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247Function: Possibly involved in structural functions as organizing other membrane components or in targeting thevesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (Bysimilarity) Genatlas biochemistry entry for SYP:synaptophysin (integral protein of small presynaptic vesicles of neurons)
Clone
Products: | | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SYP (NM_003179) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SYP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYP |
Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9): About this table
SYP for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for SYP: Syptm1Leu Syptm1Sud
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Syp):
SYP for phenotypes About GeneDecksing
|
Pathways & Interactions
for SYP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Neuroscience | | | 2 | Synaptic Vesicle Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1
Cell Signaling Technology (CST) Pathway for SYP
1  BioSystems Pathway for SYP
SYP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SYP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/33 Interacting proteins for SYP (P082473 ENSP000002632334) via UniProtKB, MINT, STRING, and/or I2D (see all 33)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
SYP for ontologies About GeneDecksing
|
Drugs & Compounds
for SYP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SYP for compounds About GeneDecksing
 Browse Tocris compounds for SYP
1 HMDB Compound for SYP About this table
10/79 Novoseek chemical compound relationships for SYP gene (see all 79) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| smcc |
69.5 |
2 |
18008084 (1), 18323171 (1) |
| paraffin |
55.8 |
19 |
1693875 (1), 1654075 (1), 9775396 (1), 15574220 (1) (see all 18) |
| reticulin |
55.6 |
1 |
16570197 (1) |
| s 100 |
54.8 |
5 |
7609154 (1), 11253140 (1), 17335582 (1), 1371487 (1) |
| mucicarmine |
54.5 |
1 |
19132778 (1) |
| hematoxylin |
44.7 |
2 |
16405409 (1), 20205830 (1) |
| b 723 |
44.6 |
7 |
10987260 (3), 12481020 (1), 12647218 (1), 20182344 (1) (see all 5) |
| 111in-pentetreotide |
40 |
2 |
19561636 (1) |
| progesterone |
39.6 |
36 |
14506675 (1), 14659309 (1), 15001999 (1), 15974816 (1) (see all 35) |
| alpha-latrotoxin |
37.6 |
2 |
15198661 (1), 1967610 (1) |
Search CenterWatch for drugs/clinical trials and news about SYP / SYPH
|
Transcripts
for SYP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SYP gene: NM_003179.2 Unigene Cluster for SYP: Synaptophysin Hs.632804 [show with all ESTs]Unigene Representative Sequence: BC0645509 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263233(uc004dmz.1 uc011mmz.1) ENST00000472598 ENST00000376303
ENST00000479808 ENST00000469389 ENST00000466635 ENST00000494396 ENST00000472737
ENST00000538567
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SYP (NM_003179) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SYP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYP |
Additional cDNA sequence: AK295524.1 AK313030.1 AK315953.1 BC032385.1 BC064550.1 X06389.1 9 DOTS entries: DT.114446 DT.100837666 DT.121307702 DT.121307680 DT.75155765 DT.91673390 DT.91993682 DT.95274943 DT.97777204 24/181 AceView cDNA sequences (see all 181): BX089443 BQ893689 BU167864 BQ639254 CR599877 AA322279 AJ011654 R84346 BX355569 BX436352 AI124821 BQ638375 AA317404 BM925290 BP353641 CR605904 BU685092 AA350971 NM_006150 AI298803 AW951240 AA524273 BM927073 CR609397
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SYP (see all 8) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SYP
|
Expression
for SYP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SYP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGCAGTGAA
About this image
See SYP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYP
SOURCE GeneReport for Unigene cluster: Hs.632804
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247Tissue specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynapticvesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype
SABiosciences Custom PCR Arrays for SYP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SYP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYP |
Orthologs
for SYP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SYP gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
SYP6 |
-- |
71(a) |
1 ↔ 1 |
2(88916335-88927920) |
African clawed frog
(Xenopus laevis) |
Amphibia |
syp-B2 |
synaptophysin |
72.58(n) |
|
AF035015.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.117162 |
Transcribed sequence with weak similarity to protein more |
74.34(n) |
|
CK353511.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
sph-16 |
SyaptoPHysin family member (sph-1) |
26(a) |
possible ortholog |
IV(8132161-8133678) |
ENSEMBL Gene Tree for SYP (if available)
TreeFam Gene Tree for SYP (if available) |
Paralogs
for SYP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SYP gene
- SYNPR2 SYPL12 SYPL22
4 SIMAP similar genes for SYP using alignment to 5 protein entries: SYPH_HUMAN (see all proteins):SYNPR SYPL1 SYPL SYPL2
SYP for paralogs About GeneDecksing
|
Genomic Variants
for SYP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SYP (49044265 - 49056718 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SYP
1 CNV: 7789
2 Inversions: 0660 37379
Human Gene Mutation Database (HGMD): SYP
Locus Specific Mutation Databases (LSDB): SYP
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYP |
|
Disorders
/ Diseases
for SYP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SYP for disorders About GeneDecksing
OMIM gene information: 313475
OMIM disorders: 300802
UniProtKB/Swiss-Prot: SYPH_HUMAN, P08247
Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mentalretardation is characterized by significantly below average general intellectual functioning associated withimpairments in adaptative behavior and manifested during the developmental period
20/207  diseases for SYP (see all 207): About MalaCardsmental retardation, x-linked mental retardation, x-linked, with or without epilepsy werdnig-hoffmann disease pure red-cell aplasia
von hippel-lindau disease atypical teratoid rhabdoid tumor pelviureteric junction obstruction primitive neuroectodermal tumor
desmoplastic small round cell tumor primary pigmented nodular adrenocortical disease supratentorial primitive neuroectodermal tumor sertoli-leydig cell tumor
mixed ductal-endocrine carcinoma subependymal giant cell astrocytoma attention deficit hyperactivity disorder perivascular epithelioid cell tumor
dysembryoplastic neuroepithelial tumor lower motor neuron disease colonic aganglionosis supranuclear palsy
18 diseases from the University of Copenhagen DISEASES database for SYP:Carcinoma Alzheimer's disease Ganglioglioma Brain cancer
Paraganglioma Dysembryoplastic neuroepithelial tumor Merkel cell carcinoma Medulloblastoma
Malignant glioma Lung cancer Brain disease Neuroblastoma
Pineoblastoma Adenoma Gangliocytoma Medulloepithelioma
Schizophrenia Melanotic neuroectodermal tumor 10/96 Novoseek disease relationships for SYP gene (see all 96) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| carcinoma neuroendocrine |
92.4 |
26 |
7832277 (2), 19047907 (1), 11176070 (1), 14533935 (1) (see all 21) |
| neurocytoma |
88.2 |
10 |
10451427 (2), 1615372 (1), 17167646 (1), 17039400 (1) (see all 8) |
| neurocytoma central |
87.6 |
12 |
20429311 (3), 1471723 (1), 2028745 (1), 8410138 (1) (see all 9) |
| carcinoid |
84.6 |
43 |
15551743 (2), 10469401 (1), 11433616 (1), 14651212 (1) (see all 42) |
| small cell lung cancer |
80.1 |
33 |
19321468 (3), 10460660 (2), 15816436 (1), 15899778 (1) (see all 27) |
| neuroendocrine tumors |
79.6 |
18 |
8287627 (3), 9744317 (1), 18430248 (1), 18726606 (1) (see all 15) |
| pineocytoma |
78.4 |
5 |
7839826 (2), 7821912 (1), 1500956 (1), 1473313 (1) |
| tumors |
77.2 |
515 |
18209916 (5), 16188147 (3), 8212457 (3), 17222630 (3) (see all 99) |
| ganglioglioma |
76.8 |
19 |
10581850 (4), 8246054 (3), 9591724 (2), 2104823 (1) (see all 12) |
| primitive neuroectodermal tumor pnet |
75.3 |
5 |
7780694 (2), 8673418 (1), 19652428 (1), 2159086 (1) |
Genetic Association Database (GAD): SYP
Human Genome Epidemiology (HuGE) Navigator: SYP (2 documents)
Export disorders for SYP gene to outside databases
|
Publications
for SYP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SYP gene, integrated from 9 sources (see all 1236):
(articles sorted by number of sources associating them with SYP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The cDNA and derived amino acid sequences for rat and human synaptophysin. (PubMed id 3120152)1, 2, 3 Suedhof T.C.... Jahn R. (1987)
- Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse. (PubMed id 1975480)1, 2, 9 Oezcelik T.... Suedhof T.C. (1990)
- Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp. (PubMed id 9344658)1, 2, 9 Fisher S.E.... Craig I.W. (1997)
- A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PubMed id 19377476)1, 2 Tarpey P.S.... Stratton M.R. (2009)
- DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters. (PubMed id 16082702)1, 4 Brookes K.J....Asherson P. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Co-localization of synaptophysin with different neuroendocrine hormones in the human gastrointestinal tract. (PubMed id 9930883)1, 9 Portela-Gomes G.M....Grimelius L. (1999)
- Synaptophysin and postsynaptic density protein 95 in the human prefrontal cortex from mid-gestation into early adulthood. (PubMed id 17916412)1, 9 Glantz L.A....Jarskog L.F. (2007)
- Interaction of the mu-opioid receptor with synaptophysin influences receptor trafficking and signaling. (PubMed id 17005904)1, 9 Liang Y.J....Koch T. (2007)
|
External Searches for SYP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SYP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SYP gene
(According to HUGE)
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Specialized Databases showing SYP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for SYP | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Synaptophysin |
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| Patent Information for SYP gene:
Search GeneIP for patents involving SYP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SYP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for SYP | | OriGene shRNA RFP for SYP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYP | | | OriGene Protein Over-expression Lysate for SYP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SYP | | OriGene 3'-UTR Clone for SYP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SYP | | OriGene Custom Protein Services for SYP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYP |
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| | Antibodies & Assays for SYP |
| | | | Search Tocris compounds for SYP |
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 | | | SYP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYP |
|  |  |  | | | | ThermoFisher Antibody for SYP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYP |
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