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SYNPR Gene

protein-coding   GIFtS: 51
GCID: GC03P063213

Synaptoporin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
synaptoporin1 2
SPO2

External Ids:    HGNC: 165071   Entrez Gene: 1322042   Ensembl: ENSG000001636307   UniProtKB: Q8TBG93   
ORGUL members:         

Export aliases for SYNPR gene to outside databases

Previous GC identifers: GC00U991103 GC03P062831 GC03P063118 GC03P063386 GC03P063404


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SYNPR Gene:
SYNPR (synaptoporin) is a protein-coding gene. Diseases associated with SYNPR include retinitis, and neuronitis. GO annotations related to this gene include transporter activity. An important paralog of this gene is SYPL1.

UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9
Function: Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By
similarity)

Gene Wiki entry for SYNPR Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYNPR gene promoter:
         STAT5B   HOXA3   Olf-1   Lmo2   POU6F1 (c2)   AP-4   Nkx2-5   Nkx5-1   GATA-6   FOXC1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYNPR promoter sequence
   Search Chromatin IP Primers for SYNPR

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYNPR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.2   Ensembl cytogenetic band:  3p14.2   HGNC cytogenetic band: 3p14.3

SYNPR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYNPR gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P063213:  view genomic region     (about GC identifiers)

Start:
63,213,991 bp from pter      End:
63,602,597 bp from pter
Size:
388,607 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9 (See protein sequence)
Recommended Name: Synaptoporin  
Size: 265 amino acids; 29166 Da
Secondary accessions: B2R675 G5E9W4
Alternative splicing: 2 isoforms:  Q8TBG9-1   Q8TBG9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYNPR: NX_Q8TBG9

Explore proteomics data for SYNPR at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn33, Asn38
  • Modification sites at PhosphoSitePlus

  • See SYNPR Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001123475.1  NP_653243.1  

    ENSEMBL proteins: 
     ENSP00000418994   ENSP00000402121   ENSP00000419441   ENSP00000295894   ENSP00000420383  
     ENSP00000420623   ENSP00000418929   ENSP00000418701   ENSP00000418123  

    SYNPR Human Recombinant Protein Products:

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    Novus Biologicals SYNPR Lysate
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for SYNPR

    SYNPR Antibody Products:

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    LSBio Antibodies in human, mouse, rat for SYNPR

    SYNPR Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for SYNPR
    Cloud-Clone Corp. CLIAs for SYNPR


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001285 Synaptophysin/porin
     IPR008253 Marvel

    Graphical View of Domain Structure for InterPro Entry Q8TBG9

    ProtoNet protein and cluster: Q8TBG9

    2 Blocks protein domains:
    IPB001285 Synaptophysin/synaptoporin
    IPB008253 Marvel


    UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9
    Similarity: Belongs to the synaptophysin/synaptobrevin family
    Similarity: Contains 1 MARVEL domain


    SYNPR for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYNPR_HUMAN, Q8TBG9
    Function: Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By
    similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
         
    SYNPR for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Synpr):
     no phenotypic analysis 

    SYNPR for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Synprtm1Sud for SYNPR

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYNPR
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SYNPR

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYNPR
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYNPR

    miRNA
    Products:
        
    miRTarBase miRNAs that target SYNPR:
    hsa-mir-877-5p (MIRT037207), hsa-mir-92a-3p (MIRT049284), hsa-mir-877-3p (MIRT036821), hsa-mir-335-5p (MIRT017484), hsa-let-7a-5p (MIRT052365), hsa-mir-25-3p (MIRT050282)

    Block miRNA regulation of human, mouse, rat SYNPR using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYNPR (see all 21):
    hsa-miR-875-3p hsa-miR-448 hsa-miR-181c hsa-miR-410 hsa-miR-2115 hsa-miR-29a* hsa-miR-3121-3p hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidSYNPR 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SYNPR
    Predesigned siRNA for gene silencing in human, mouse, rat SYNPR

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): SYNPR (NM_001130003)
    Sino Biological Human cDNA Clone for SYNPR
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYNPR
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNPR

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for SYNPR 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNPR


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SYNPR_HUMAN, Q8TBG9: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane
    protein (By similarity). Cell junction, synapse, synaptosome (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    endoplasmic reticulum1
    lysosome1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008021synaptic vesicle ----
    GO:0016020membrane ----
    GO:0016021integral component of membrane ----
    GO:0030054cell junction IEA--
    GO:0030285integral component of synaptic vesicle membrane IBA--

    SYNPR for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYNPR
    Interactions:

        Search GeneGlobe Interaction Network for SYNPR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for SYNPR (ENSP000004189944) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDK16ENSP000004057984STRING: ENSP00000405798
    MYO5CENSP000002618394STRING: ENSP00000261839
    OPRM1ENSP000003946244STRING: ENSP00000394624
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    SRCIN1ENSP000002646594STRING: ENSP00000264659
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYNPR



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SYNPR gene (2 alternative transcripts): 
    NM_001130003.1  NM_144642.4  

    Unigene Cluster for SYNPR:

    Synaptoporin
    Hs.648668  [show with all ESTs]
    Unigene Representative Sequence: NM_144642
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000478456 ENST00000478300(uc003dlp.3 uc011bfk.2 uc011bfl.2)
    ENST00000450542 ENST00000468110 ENST00000496889 ENST00000460142 ENST00000493532
    ENST00000467934 ENST00000295894(uc003dlq.3 uc010hnt.3 uc011bfm.2)
    ENST00000498449 ENST00000472899 ENST00000479198 ENST00000478744 ENST00000460711
    ENST00000465156
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SYNPR using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYNPR (see all 21):
    hsa-miR-875-3p hsa-miR-448 hsa-miR-181c hsa-miR-410 hsa-miR-2115 hsa-miR-29a* hsa-miR-3121-3p hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidSYNPR 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SYNPR
    Predesigned siRNA for gene silencing in human, mouse, rat SYNPR
    Clone
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    OriGene clones in human, mouse for SYNPR (see all 11)
    OriGene ORF clones in mouse, rat for SYNPR
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SYNPR (NM_001130003)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYNPR
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNPR
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SYNPR
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SYNPR
      QuantiTect SYBR Green Assays in human, mouse, rat SYNPR
      QuantiFast Probe-based Assays in human, mouse, rat SYNPR

    Additional mRNA sequence: 

    AK122831.1 AK293628.1 AK309017.1 AK312465.1 AK315958.1 AL834457.1 BC022518.1 CR936762.1 

    7 DOTS entries:

    DT.444829  DT.95179470  DT.101978054  DT.120927907  DT.95265987  DT.92062306  DT.120927913 

    Selected AceView cDNA sequences (see all 45):

    AL834457 BX459914 AA322412 AI638401 AA322328 NM_144642 AF411860 AK122831 
    CA389414 BC022518 H98620 BI755007 BI599795 BM712468 N27906 BI603103 
    BI457728 BX409725 BG706021 AV718200 BI600305 N55042 BI599291 BI597439 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SYNPR    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
    SP1:                    -           -                           
    SP2:                                -                           
    SP3:                    -                                       
    SP4:                    -           -     -                     


    ECgene alternative splicing isoforms for SYNPR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYNPR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATATTCTC
    SYNPR Expression
    About this image


    SYNPR expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 5 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Epithelial Cells
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Bone (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Eye (Sensory Organs)
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
    SYNPR Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYNPR Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.648668
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNPR

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SYNPR gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Synpr1 , 5 synaptoporin1, 5 89.47(n)1
    95.44(a)1
      14 (6.86 cM)5
    720031  NM_028052.41  NP_082328.31 
     132847805 
    chicken
    (Gallus gallus)
    Aves SYNPR1 synaptoporin 77.39(n)
    84.31(a)
      396359  NM_205394.1  NP_990725.1 
    lizard
    (Anolis carolinensis)
    Reptilia SYNPR6
    synaptoporin
    82(a)
    1 ↔ 1
    GL343210.1(2155334-2227278)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia synpr1 synaptoporin 76.38(n)
    83(a)
      780146  NM_001079221.1  NP_001072689.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5582901 synaptoporin-like 66.31(n)
    68.82(a)
      558290  XM_681491.5  XP_686583.4 
    worm
    (Caenorhabditis elegans)
    Secernentea sph-16
    Protein SPH-1 (sph-1) mRNA, complete cds
    25(a)
    1 → many
    IV(8132175-8133692) WBGene00004979


    ENSEMBL Gene Tree for SYNPR (if available)
    TreeFam Gene Tree for SYNPR (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYNPR gene
    SYPL12  SYP2  SYPL22  
    4 SIMAP similar genes for SYNPR using alignment to 8 protein entries:     SYNPR_HUMAN (see all proteins):
    SYP    SYPL    SYPL1    SYPL2

    SYNPR for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYNPR (see all 4835)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs622513341,2
    C--63261925(+) AACAAG/CACACA 1 -- us2k15Minor allele frequency- C:0.18NA WA EA 362
    rs758996431,2
    C,F--63261964(+) GATATA/GTAGAT 1 -- us2k12Minor allele frequency- G:0.11CSA WA 120
    rs74335821,2
    C,F,H--63261972(+) GATGTG/TGAGGT 1 -- us2k126Minor allele frequency- T:0.34NS EA NA WA CSA 2496
    rs1455280641,2
    --63262033(+) TGGACC/TTCTGA 1 -- us2k10--------
    rs1488501341,2
    --63262109(+) GACTGC/TCCTAG 1 -- us2k10--------
    rs1869177021,2
    --63262137(+) TCTCAC/TTGGGT 1 -- us2k10--------
    rs173743791,2
    C,F,H--63262264(+) ATGGTA/GGGGTA 1 -- us2k121Minor allele frequency- G:0.19NA NS EA WA 2472
    rs113981091,2
    C--63262296(+) CCCCC-/CACCCC 1 -- us2k10--------
    rs2015202691,2
    C--63262300(+) TCCCC-/TCCACC 1 -- us2k10--------
    rs126303091,2
    C,F,H--63262486(+) GAGCAG/AGGGGC 1 -- us2k110Minor allele frequency- A:0.27NS EA WA NA 770

    HapMap Linkage Disequilibrium report for SYNPR (63213991 - 63463991 bp, first 250kb of SYNPR)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SYNPR (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422509CNV Deletion17116639
    esv1696258CNV Deletion17803354
    nsv3848CNV Insertion18451855
    esv1548229CNV Insertion17803354
    esv271251CNV Insertion20981092
    esv273179CNV Insertion20981092
    esv25050CNV Loss19812545
    nsv876885CNV Loss21882294
    nsv834716CNV Loss17160897
    esv23041CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYNPR
    DNA2.0 Custom Variant and Variant Library Synthesis for SYNPR

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for SYNPR:    
    About MalaCards
    retinitis    neuronitis


    SYNPR for disorders           About GeneDecksing

    Genetic Association Database (GAD): SYNPR
    Human Genome Epidemiology (HuGE) Navigator: SYNPR (1 document)

    Export disorders for SYNPR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYNPR gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with SYNPR)
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    1. Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein. (PubMed id 12974474)1, 3, 9 Dai J....Mao Y. (Mol. Biol. Rep. 2003)
    2. Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human. (PubMed id 8034131)1, 3, 9 Leube R.E. (Differentiation 1994)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    10. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 132204 HGNC: 16507 AceView: SYNPR Ensembl:ENSG00000163630 euGenes: HUgn132204
    ECgene: SYNPR H-InvDB: SYNPR

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYNPR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYNPR gene:
    Search GeneIP for patents involving SYNPR

    GeneCards and IP:
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