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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SYNPR Gene

protein-coding GIFtS: 48
GCID: GC03P063213

synaptoporin

Explore 1 disease affiliated with
SYNPR via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Synaptoporin¹
SPO¹ ²
MGC26651¹

External Ids:	HGNC: 16507¹	Entrez Gene: 132204²	Ensembl: ENSG00000163630⁷	UniProtKB: Q8TBG9³

Export aliases for SYNPR gene to outside databases

Previous GC identifers: GC00U991103 GC03P062831 GC03P063118 GC03P063386 GC03P063404

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9

Function: Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)

Gene Wiki entry for SYNPR

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_022517.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SYNPR gene promoter:
STAT5B HOXA3 Olf-1 Lmo2 POU6F1 (c2) AP-4 Nkx2-5 Nkx5-1 GATA-6 FOXC1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYNPR promoter sequence

Search SABiosciences Chromatin IP Primers for SYNPR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYNPR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.2 Ensembl cytogenetic band: 3p14.2 HGNC cytogenetic band: 3p14.3

SYNPR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYNPR gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P063213: view genomic region (about GC identifiers)

Start:	63,213,991 bp from pter	End:	63,602,597 bp from pter
Size:	388,607 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9 (See protein sequence)

Recommended Name: Synaptoporin

Size: 265 amino acids; 29166 Da

Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein

(By similarity). Cell junction, synapse, synaptosome (By similarity)

Secondary accessions: B2R675 G5E9W4

Alternative splicing: 2 isoforms: Q8TBG9-1 Q8TBG9-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYNPR: NX_Q8TBG9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8TBG9

SYNPR Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001123475.1 NP_653243.1

ENSEMBL proteins:

ENSP00000418994 ENSP00000402121 ENSP00000419441 ENSP00000295894 ENSP00000420383

ENSP00000420623 ENSP00000418929 ENSP00000418701 ENSP00000418123

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SYNPR OriGene Protein Over-expression Lysate (see all 2): SYNPR OriGene Custom Protein Services for SYNPR
	GenScript Custom Purified and Recombinant Proteins Services for SYNPR
	Novus Biologicals SYNPR Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SYNPR

Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008021	synaptic vesicle	--	--
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	IEA	--
GO:0019717	synaptosome	--	--
GO:0030054	cell junction	IEA	--

SYNPR for ontologies About GeneDecksing

SYNPR Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of SYNPR
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	Browse OriGene Antibodies OriGene Custom Antibody Services for SYNPR
	GenScript Custom Superior Antibodies Services for SYNPR
	Novus Biologicals SYNPR Antibodies
	Search for Antibodies for SYNPR at Abcam
	Uscn Antibodies for SYNPR
	Search ThermoFisher Antibodies for SYNPR

Assay Products for SYNPR:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SYNPR
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SYNPR

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SYNPR for domains About GeneDecksing

3 InterPro domains/families:

IPR021128 MARVEL-like_dom

IPR001285 Synaptophysin/porin

IPR008253 Marvel

Graphical View of Domain Structure for InterPro Entry Q8TBG9

ProtoNet protein and cluster: Q8TBG9

2 Blocks protein families:

IPB001285 Synaptophysin/synaptoporin

IPB008253 Marvel

UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9

Similarity: Belongs to the synaptophysin/synaptobrevin family

Similarity: Contains 1 MARVEL domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SYNPR_HUMAN, Q8TBG9

Function: Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SYNPR Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYNPR
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate SYNPR (see all 21):
		hsa-miR-875-3p hsa-miR-448 hsa-miR-181c hsa-miR-410 hsa-miR-2115 hsa-miR-29a* hsa-miR-3121-3p hsa-miR-580

		SwitchGear 3'UTR luciferase reporter plasmid: SYNPR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYNPR (see all 7) OriGene shRNA RFP: SYNPR OriGene siRNA: SYNPR
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYNPR

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SYNPR

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYNPR (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYNPR (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SYNPR (NM_001130003)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYNPR
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNPR

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SYNPR
		Search LifeMap BioReagents cell lines for SYNPR

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNPR

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	IEA	--

SYNPR for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Synpr^tm1Sud for SYNPR
     1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Synpr):

no phenotypic analysis

SYNPR for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SYNPR

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SYNPR
Search CenterWatch for drugs/clinical trials and news about SYNPR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SYNPR gene (2 alternative transcripts):

NM_001130003.1 NM_144642.4

Unigene Cluster for SYNPR:

Synaptoporin

Hs.648668 [show with all ESTs]

Unigene Representative Sequence: NM_144642

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000478456 ENST00000478300(uc003dlp.3 uc011bfk.2 uc011bfl.2)

ENST00000450542 ENST00000468110 ENST00000496889 ENST00000460142 ENST00000493532

ENST00000467934 ENST00000295894(uc003dlq.3 uc010hnt.3 uc011bfm.2)

ENST00000498449 ENST00000472899 ENST00000479198 ENST00000478744 ENST00000460711

ENST00000465156

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SYNPR Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYNPR
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate SYNPR (see all 21):
		hsa-miR-875-3p hsa-miR-448 hsa-miR-181c hsa-miR-410 hsa-miR-2115 hsa-miR-29a* hsa-miR-3121-3p hsa-miR-580

		SwitchGear 3'UTR luciferase reporter plasmid: SYNPR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYNPR (see all 7) OriGene shRNA RFP: SYNPR OriGene siRNA: SYNPR
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYNPR

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SYNPR (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SYNPR (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SYNPR (NM_001130003)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYNPR
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNPR

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYNPR Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYNPR
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYNPR
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYNPR

Additional cDNA sequence:

AK122831.1 AK293628.1 AK309017.1 AK312465.1 AK315958.1 AL834457.1 BC022518.1 CR936762.1

7 DOTS entries:

DT.444829 DT.95179470 DT.101978054 DT.120927907 DT.95265987 DT.92062306 DT.120927913

24/45 AceView cDNA sequences (see all 45):

AF411860 AL834457 AA322412 BC022518 NM_144642 AA322328 AI638401 BX459914

CA389414 AK122831 BE328086 AV718200 AI962407 N55042 N27906 BI597439

BI603103 BI600305 BX409725 BG706021 BI755007 BI599795 BM712468 H98620

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for SYNPR About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7
SP1:							-				-
SP2:											-
SP3:							-
SP4:							-				-		-

ECgene alternative splicing isoforms for SYNPR

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SYNPR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATATTCTC

About this image

SYNPR expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

8 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Dorsal Columns

Dorsal Spinal Cord Progenitor Cells

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Neural Tube

Neural Tube

Neural Tube

Spinal Dorsal Columns

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

See SYNPR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SYNPR

SOURCE GeneReport for Unigene cluster: Hs.648668

SABiosciences Custom PCR Arrays for SYNPR

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SYNPR Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SYNPR
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYNPR
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYNPR

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNPR

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SYNPR gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Synpr^{1 , 5}	synaptoporin^{1, 5}	89.47(n)¹ 95.44(a)¹		14 (6.86 cM)⁵ 72003¹ NM_028052.4¹ NP_082328.3¹ 13284780⁵
chicken (Gallus gallus)	Aves	SYNPR¹	synaptoporin	77.47(n) 83.98(a)		396359 NM_205394.1 NP_990725.1
lizard (Anolis carolinensis)	Reptilia	SYNPR⁶	--	79(a)	1 ↔ 1	GL343210.1(2157450-2188834)
zebrafish (Danio rerio)	Actinopterygii	LOC558290¹	synaptoporin-like	65.72(n) 67.49(a)		558290 XM_681491.4 XP_686583.4
worm (Caenorhabditis elegans)	Secernentea	sph-1⁶	SyaptoPHysin family member (sph-1)	24(a)	possible ortholog	IV(8132161-8133678)

ENSEMBL Gene Tree for SYNPR (if available)
TreeFam Gene Tree for SYNPR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SYNPR gene

SYPL1² SYP² SYPL2²

4 SIMAP similar genes for SYNPR using alignment to 8 protein entries: SYNPR_HUMAN (see all proteins):

SYP SYPL SYPL1 SYPL2

SYNPR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs62251334^1,2	C,	--	63261925(+)	`AACAAG/CACACA`	1	--	us2k¹		5		NA WA EA	362
rs75899643^1,2		--	63261964(+)	`GATATA/GTAGAT`	1	--	us2k¹		2		CSA WA	120
rs7433582^1,2	C,F,H,	--	63261972(+)	`GATGTG/TGAGGT`	1	--	us2k¹		26		NS EA NA WA CSA	2496
rs145528064^1,2		--	63262033(+)	`TGGACC/TTCTGA`	1	--	us2k¹		0	--	--	--	--
rs148850134^1,2		--	63262109(+)	`GACTGC/TCCTAG`	1	--	us2k¹		0	--	--	--	--
rs186917702^1,2		--	63262137(+)	`TCTCAC/TTGGGT`	1	--	us2k¹		0	--	--	--	--
rs17374379^1,2	C,F,H,	--	63262264(+)	`ATGGTA/GGGGTA`	1	--	us2k¹		21		NA NS EA WA	2472
rs35682161^1,2	C,	--	63262296(+)	`TAGTT-/CCCCCC`	1	--	us2k¹		0	--	--	--	--
rs11398109^1,2	C	--	63262297(+)	`CCCCC-/CACCCC`	1	--	us2k¹		0	--	--	--	--
rs201520269^1,2	C,	--	63262300(+)	`TCCCC-/TCCACC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SYNPR (63213991 - 63463991 bp, first 250kb of SYNPR)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SYNPR
2 CNVs: 5370 68392
1 Indel: 68393

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYNPR

DNA2.0 Custom Variant and Variant Library Synthesis for SYNPR

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SYNPR for disorders About GeneDecksing

1 disease for SYNPR: About MalaCards

neuronitis

Human Genome Epidemiology (HuGE) Navigator: SYNPR (1 document)

Export disorders for SYNPR gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SYNPR gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SYNPR)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein. (PubMed id 12974474)^{1, 3, 9} Dai J....Mao Y. (2003)
Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human. (PubMed id 8034131)^{1, 3, 9} Leube R.E. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The LIFEdb database in 2006. (PubMed id 16381901)¹ Mehrle A....Wiemann S. (2006)
From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)¹ Wiemann S....Poustka A. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 132204	HGNC: 16507	AceView: SYNPR	Ensembl:ENSG00000163630	euGenes: HUgn132204
ECgene: SYNPR	H-InvDB: SYNPR

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SYNPR	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SYNPR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SYNPR gene:
Search GeneIP for patents involving SYNPR

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for SYNPR
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SYNPR
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYNPR
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYNPR
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYNPR
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	GenScript Custom Purified and Recombinant Proteins Services for SYNPR		GenScript cDNA clones with any tag delivered in your preferred vector for SYNPR
	GenScript Custom Assay Services for SYNPR		GenScript Custom Superior Antibodies Services for SYNPR
	GenScript Custom overexpressing Cell Line Services for SYNPR		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNPR

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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SYNPR Gene

synaptoporin

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SYNPR Gene

synaptoporin

Aliasesfor SYNPR gene

Summariesfor SYNPR gene

Genomic Viewsfor SYNPR gene

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Protein Domains /Familiesfor SYNPR gene

Functionfor SYNPR gene

Pathways & Interactionsfor SYNPR gene

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Specialized Databases showing SYNPR gene

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Summaries
for SYNPR gene

Genomic Views
for SYNPR gene

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for SYNPR gene

Protein Domains /
Families
for SYNPR gene

Function
for SYNPR gene

Pathways & Interactions
for SYNPR gene

Drugs & Compounds
for SYNPR gene

Transcripts
for SYNPR gene

Expression
for SYNPR gene

Orthologs
for SYNPR gene

Paralogs
for SYNPR gene

Genomic Variants
for SYNPR gene

Disorders / Diseases
for SYNPR gene

Publications
for SYNPR gene

Intellectual Property
for SYNPR gene

Products
for SYNPR gene