Aliases for SYNJ1 Gene
External Ids for SYNJ1 Gene
Previous GeneCards Identifiers for SYNJ1 Gene
This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for SYNJ1 Gene
SYNJ1 (Synaptojanin 1) is a Protein Coding gene. Diseases associated with SYNJ1 include Parkinson Disease 20, Early-Onset and Atypical Juvenile Parkinsonism. Among its related pathways are Inositol phosphate metabolism (KEGG) and Inositol phosphate metabolism (REACTOME). GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is SYNJ2.
UniProtKB/Swiss-Prot for SYNJ1 Gene
Inositol 5-phosphatase which has a role in clathrin-mediated endocytosis.