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SYNGR1 Gene

protein-coding   GIFtS: 57
GCID: GC22P039745

Synaptogyrin 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synaptogyrin 11 2
synaptogyrin-12

External Ids:    HGNC: 114981   Entrez Gene: 91452   Ensembl: ENSG000001003217   OMIM: 6039255   UniProtKB: O437593   

Export aliases for SYNGR1 gene to outside databases

Previous GC identifers: GC22P036360 GC22P037989 GC22P037988 GC22P038070 GC22P022711


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SYNGR1 Gene:
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact
function of this protein is unclear, but studies of a similar murine protein suggest that it functions in
synaptic plasticity without being required for synaptic transmission. The gene product belongs to the
synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been
identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for SYNGR1 Gene:
SYNGR1 (synaptogyrin 1) is a protein-coding gene. An important paralog of this gene is SYNGR4.

UniProtKB/Swiss-Prot: SNG1_HUMAN, O43759
Function: Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)

Gene Wiki entry for SYNGR1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYNGR1 gene promoter:
         PPAR-gamma1   Pax-2   Pax-2a   PPAR-gamma2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYNGR1 promoter sequence
   Search Chromatin IP Primers for SYNGR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYNGR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13

SYNGR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYNGR1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039745:  view genomic region     (about GC identifiers)

Start:
39,745,930 bp from pter      End:
39,781,593 bp from pter
Size:
35,664 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNG1_HUMAN, O43759 (See protein sequence)
Recommended Name: Synaptogyrin-1  
Size: 233 amino acids; 25456 Da
Secondary accessions: A6NP69 A8K0E2 O43757 O43758 Q53Y02 Q96J56 Q9UGZ4
Alternative splicing: 3 isoforms:  O43759-1   O43759-2   O43759-3   

Explore the universe of human proteins at neXtProt for SYNGR1: NX_O43759

Explore proteomics data for SYNGR1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SYNGR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_004702.2  NP_663783.1  NP_663791.1  

    ENSEMBL proteins: 
     ENSP00000318845   ENSP00000216155   ENSP00000412442   ENSP00000385447   ENSP00000332287  
     ENSP00000370946  

    SYNGR1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SYNGR1

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR016579 Synaptogyrin
     IPR008253 Marvel

    Graphical View of Domain Structure for InterPro Entry O43759

    ProtoNet protein and cluster: O43759

    1 Blocks protein domain: IPB008253 Marvel

    UniProtKB/Swiss-Prot: SNG1_HUMAN, O43759
    Similarity: Belongs to the synaptogyrin family
    Similarity: Contains 1 MARVEL domain


    Find genes that share domains with SYNGR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNG1_HUMAN, O43759
    Function: Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)

         Genatlas biochemistry entry for SYNGR1:
    synaptogyrin,putative vesicle protein,expressed in neurons of the central nervous system,with three alternatively
    spliced isoforms,SYNGR1a,SYNGR1b,SYNGR1c

    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Syngr1):
     nervous system  no phenotypic analysis 

    Find genes that share phenotypes with SYNGR1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Syngr1tm1Sud for SYNGR1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYNGR1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYNGR1
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    miRNA
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    miRTarBase miRNAs that target SYNGR1:
    hsa-mir-1301-3p (MIRT036022), hsa-mir-215-5p (MIRT024495), hsa-mir-192-5p (MIRT026210)

    Block miRNA regulation of human, mouse, rat SYNGR1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYNGR1 (see all 44):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-486-3p hsa-miR-218 hsa-miR-654-5p hsa-miR-1243 hsa-miR-556-3p hsa-miR-30b*
    SwitchGear 3'UTR luciferase reporter plasmidSYNGR1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SYNGR1

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    GenScript: all cDNA clones in your preferred vector (see all 3): SYNGR1 (NM_004711)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNGR1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNGR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNG1_HUMAN, O43759: Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified
    by mass spectrometry in melanosome fractions from stage I to stage IV
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008021synaptic vesicle ----
    GO:0016020membrane ----
    GO:0016021integral component of membrane NAS9760194
    GO:0030054cell junction IEA--
    GO:0030672synaptic vesicle membrane IEA--

    Find genes that share ontologies with SYNGR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYNGR1
    Interactions:

        Search GeneGlobe Interaction Network for SYNGR1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for SYNGR1 (O437593 ENSP000003322874) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    GRIN1Q055863I2D: score=1 
    GRIN2BQ132243I2D: score=1 
    YWHABP319463I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006605protein targeting IEA--
    GO:0048169regulation of long-term neuronal synaptic plasticity ISS--
    GO:0048172regulation of short-term neuronal synaptic plasticity ISS--

    Find genes that share ontologies with SYNGR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYNGR1 (SNG1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYNGR1 gene (3 alternative transcripts): 
    NM_004711.4  NM_145731.3  NM_145738.2  

    Unigene Cluster for SYNGR1:

    Synaptogyrin 1
    Hs.216226  [show with all ESTs]
    Unigene Representative Sequence: NM_004711
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000318801(uc003axo.4) ENST00000216155 ENST00000415332 ENST00000406293
    ENST00000328933(uc003axq.4) ENST00000489206 ENST00000381535(uc003axs.4)

    miRNA
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    Block miRNA regulation of human, mouse, rat SYNGR1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYNGR1 (see all 44):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-486-3p hsa-miR-218 hsa-miR-654-5p hsa-miR-1243 hsa-miR-556-3p hsa-miR-30b*
    SwitchGear 3'UTR luciferase reporter plasmidSYNGR1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SYNGR1
    Predesigned siRNA for gene silencing in human, mouse, rat SYNGR1
    Clone
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    OriGene clones in human, mouse for SYNGR1 (see all 18)
    OriGene ORF clones in mouse, rat for SYNGR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): SYNGR1 (NM_004711)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYNGR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYNGR1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SYNGR1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SYNGR1
      QuantiTect SYBR Green Assays in human, mouse, rat SYNGR1
      QuantiFast Probe-based Assays in human, mouse, rat SYNGR1

    Additional mRNA sequence: 

    AJ002303.1 AJ002304.1 AJ002305.1 AK289507.1 AK295863.1 AK308714.1 BC000731.2 BT007135.1 
    CR456590.1 

    8 DOTS entries:

    DT.217979  DT.95097165  DT.92424981  DT.95200856  DT.75176502  DT.92424980  DT.100781241  DT.100841680 

    Selected AceView cDNA sequences (see all 243):

    AA317308 AA323040 NM_145738 BU684728 R88565 BT007135 AI299850 AI278338 
    Z38383 AA324724 BM716230 BI488579 CR592136 BM479463 BU731216 BG742766 
    BC000731 BU954309 BQ898157 N54744 CD722821 BM695202 BI755465 AL040124 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SYNGR1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8
    SP1:                          -     -     -                                       
    SP2:              -           -     -     -                                       
    SP3:              -           -     -     -                 -     -               
    SP4:              -                       -                                       
    SP5:              -           -     -                                             


    ECgene alternative splicing isoforms for SYNGR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYNGR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SYNGR1 Expression
    About this image


    SYNGR1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Neurons
             Mature Horizontal Cells Inner Nuclear Layer
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer
     
     Ovary (Reproductive System)
    SYNGR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYNGR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.216226
        Custom PCR Arrays for SYNGR1
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SYNGR1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syngr11 , 5 synaptogyrin 11, 5 90.56(n)1
    94.06(a)1
      15 (37.85 cM)5
    209721  NM_207708.11  NP_997591.11 
     800913345 
    chicken
    (Gallus gallus)
    Aves SYNGR11 synaptogyrin 1 78.3(n)
    77.36(a)
      418015  NM_001252278.1  NP_001239207.1 
    lizard
    (Anolis carolinensis)
    Reptilia SYNGR16
    synaptogyrin 1
    78(a)
    1 ↔ 1
    5(24660050-24699201)
    African clawed frog
    (Xenopus laevis)
    Amphibia AB072005.12   -- 75.16(n)    AB072005.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AL921056.12   -- 75.86(n)    AL921056.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta synaptogyrin1 , 3 regulation of calcium ion dependent
    exocytosis3
    synaptogyrin1
    42(a)3
    57.5(n)1
    43.27(a)1
      50C63
    365331  NM_137064.21  NP_610908.11 
    worm
    (Caenorhabditis elegans)
    Secernentea sng-11 sng-1 44.86(n)
    30.86(a)
      180995  NM_076838.4  NP_509239.1 


    ENSEMBL Gene Tree for SYNGR1 (if available)
    TreeFam Gene Tree for SYNGR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYNGR1 gene
    SYNGR42  SYNGR32  SYNGR22  
    3 SIMAP similar genes for SYNGR1 using alignment to 5 protein entries:     SNG1_HUMAN (see all proteins):
    SYNGR3    SYNGR2    SYNGR4

    Find genes that share paralogs with SYNGR1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYNGR1 (see all 934)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1378858631,2
    --22709431(+) CTTTTC/GTTTCT 2 -- us2k10--------
    rs1120863721,2
    C--22709443(+) TCTTTC/TTTTTT 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs110899511,2
    C,A,H--39743979(+) ttttgG/Tatttt 2 -- us2k10--------
    rs1845495361,2
    --39744150(+) TTGGTA/GAGGTG 2 -- us2k10--------
    rs1890948141,2
    --39744163(+) TAACTA/GTTCAA 2 -- us2k10--------
    rs1376951,2
    C,F--39744223(+) cgaacG/Attctt 2 -- us2k12Minor allele frequency- A:0.04NA EA 240
    rs59957141,2
    C--39744316(+) aacaaG/Tgtctt 2 -- us2k10--------
    rs119135991,2
    C,F,H--39744538(+) gctggG/Tactac 2 -- us2k12Minor allele frequency- T:0.25NA WA 4
    rs1430626101,2
    C--39744691(+) CACTGC/TGCCCG 2 -- us2k10--------
    rs1841438161,2
    --39744714(+) GCTTTC/GTTCTA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SYNGR1 (39745930 - 39781593 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SYNGR1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv915099CNV Loss21882294
    nsv834199CNV Loss17160897
    nsv915098CNV Loss21882294
    nsv834198CNV Loss17160897
    nsv817996CNV Gain17921354

    Human Gene Mutation Database (HGMD): SYNGR1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYNGR1
    DNA2.0 Custom Variant and Variant Library Synthesis for SYNGR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603925    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for SYNGR1:
    Schizophrenia

    Find genes that share disorders with SYNGR1           About GenesLikeMe

    Genetic Association Database (GAD): SYNGR1
    Human Genome Epidemiology (HuGE) Navigator: SYNGR1 (4 documents)

    Export disorders for SYNGR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYNGR1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with SYNGR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human synaptogyrin gene family. (PubMed id 9760194)1, 2, 3 Kedra D....Dumanski J.P. (Hum. Genet. 1998)
    2. Association study and mutational screening of SYNGR1 as a candidate susceptibility gene for schizophrenia. (PubMed id 19641478)1, 4, 9 Iatropoulos P....Barlati S. (Psychiatr. Genet. 2009)
    3. Identification of rare mutations of synaptogyrin 1 gene in patients with schizophrenia. (PubMed id 17049558)1, 2, 9 Cheng M.C. and Chen C.H. (J. Psychiatr. Res. 2007)
    4. A nonsense mutation in the synaptogyrin 1 gene in a family with schizophrenia. (PubMed id 14732601)1, 4, 9 Verma R....Brahmachari S.K. (Biol. Psychiatry 2004)
    5. No association between bipolar disorder and syngr1 or synapsin II polymorphisms in the Han Chinese population. (PubMed id 19665806)1, 4 Wang Y....Li S. (Psychiatry Res 2009)
    6. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (J. Proteome Res. 2006)
    7. SYNGR1 is associated with schizophrenia and bipolar disorder in southern India. (PubMed id 16215643)1, 4 Verma R....Brahmachari S.K. (J. Hum. Genet. 2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    10. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. (PubMed id 10595519)1, 3 Janz R....Bolshakov V.Y. (Neuron 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9145 HGNC: 11498 AceView: SYNGR1 Ensembl:ENSG00000100321 euGenes: HUgn9145
    ECgene: SYNGR1 H-InvDB: SYNGR1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYNGR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYNGR1 gene:
    Search GeneIP for patents involving SYNGR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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