Aliases for SYNE3 Gene
External Ids for SYNE3 Gene
Previous HGNC Symbols for SYNE3 Gene
Previous GeneCards Identifiers for SYNE3 Gene
GeneCards Summary for SYNE3 Gene
SYNE3 (Spectrin Repeat Containing Nuclear Envelope Family Member 3) is a Protein Coding gene. GO annotations related to this gene include actin binding and actin filament binding.
UniProtKB/Swiss-Prot for SYNE3 Gene
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.