Aliases for SYNE3 Gene
External Ids for SYNE3 Gene
Previous HGNC Symbols for SYNE3 Gene
Previous GeneCards Identifiers for SYNE3 Gene
GeneCards Summary for SYNE3 Gene
SYNE3 (Spectrin Repeat Containing, Nuclear Envelope Family Member 3) is a Protein Coding gene. GO annotations related to this gene include actin binding.
UniProtKB/Swiss-Prot for SYNE3 Gene
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.