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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYNE3 Gene

protein-coding   GIFtS: 43
GCID: GC14M095884

Spectrin Repeat Containing, Nuclear Envelope Family Member...

(Previous name: chromosome 14 open reading frame 49)
(Previous symbol: C14orf49)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Spectrin Repeat Containing, Nuclear Envelope Family Member 31 2     NET532
C14orf491 2 3 5     Nesp32
Nuclear Envelope Spectrin Repeat Protein 32 3     nesprin-32
Chromosome 14 Open Reading Frame 491     

External Ids:    HGNC: 198611   Entrez Gene: 1611762   Ensembl: ENSG000001764387   OMIM: 6108615   UniProtKB: Q6ZMZ33   

Export aliases for SYNE3 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SYNE3 Gene: 
SYNE3 (spectrin repeat containing, nuclear envelope family member 3) is a protein-coding gene. Diseases associated with SYNE3 include endotheliitis. GO annotations related to this gene include protein binding and actin binding.

UniProtKB/Swiss-Prot: SYNE3_HUMAN, Q6ZMZ3
Function: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the
nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal
filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring
protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate
filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for
flow-induced centrosome polarization and directional migration in aortic endothelial cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SYNE3
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SYNE3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYNE3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.13   Ensembl cytogenetic band:  14q32.13   HGNC cytogenetic band: 14q32.13

SYNE3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYNE3 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M095884:  view genomic region     (about GC identifiers)

Start:
95,883,831 bp from pter      End:
95,942,173 bp from pter
Size:
58,343 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYNE3_HUMAN, Q6ZMZ3 (See protein sequence)
Recommended Name: Nesprin-3  
Size: 975 amino acids; 112216 Da
Subunit: Component of LINC complexes composed of SUN domain-containing proteins SUN1 or SUN2 coupled to KASH
domain-containing proteins (SYNE1, SYNE2 or SYNE3), also called nesprins. Interacts with PLEC (via actin-binding
domain). Interacts with DST (By similarity). Interacts with SYNE1 via spectrin repeats
Subcellular location: Nucleus outer membrane; Single-pass type IV membrane protein. Nucleus envelope.
Note=Localized uniformly throughout the nuclear envilope in aortic endothelial cells. Located at the rough
reticulum endoplasmic (RER) in some cells
Sequence caution: Sequence=BAC05312.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAD18582.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD62365.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6H8H3 Q86SX5 Q8N7G8
Alternative splicing: 3 isoforms:  Q6ZMZ3-1   Q6ZMZ3-2   Q6ZMZ3-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SYNE3: NX_Q6ZMZ3

Explore proteomics data for SYNE3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZMZ3

  • SYNE3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYNE3 Protein Expression
    REFSEQ proteins: NP_689805.3  
    ENSEMBL proteins: 
     ENSP00000334308   ENSP00000452154   ENSP00000450562   ENSP00000450774  

    Human Recombinant Protein Products for SYNE3: 
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SYNE3
    GenScript Custom Purified and Recombinant Proteins Services for SYNE3
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IDA--
    GO:0005640nuclear outer membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0034993SUN-KASH complex IDA18396275

    SYNE3 for ontologies           About GeneDecksing



    SYNE3 Antibody Products: 
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    Abcam antibodies for SYNE3
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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR002017 Spectrin_repeat
     IPR012315 KASH
     IPR018159 Spectrin/alpha-actinin

    Graphical View of Domain Structure for InterPro Entry Q6ZMZ3

    ProtoNet protein and cluster: Q6ZMZ3

    UniProtKB/Swiss-Prot: SYNE3_HUMAN, Q6ZMZ3
    Domain: The KASH domain is involved in the binding to SUN1 and SUN2 through recognition of their SUN domains
    Similarity: Belongs to the nesprin family
    Similarity: Contains 1 KASH domain
    Similarity: Contains 2 spectrin repeats


    SYNE3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYNE3_HUMAN, Q6ZMZ3
    Function: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the
    nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal
    filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring
    protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate
    filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for
    flow-induced centrosome polarization and directional migration in aortic endothelial cells

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005515protein binding IPI18396275
         
    SYNE3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYNE3 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYNE3 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYNE3
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNE3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYNE3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for SYNE3 (Q6ZMZ33 ENSP000003343084) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFKBIAP259633I2D: score=2 
    SUN1ENSP000003840154STRING: ENSP00000384015
    SUN2ENSP000002160644STRING: ENSP00000216064
    SYNE1ENSP000002653684STRING: ENSP00000265368
    SYNE2ENSP000003507194STRING: ENSP00000350719
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IMP--
    GO:0008360regulation of cell shape IMP--
    GO:0090286cytoskeletal anchoring at nuclear membrane IDA18396275

    SYNE3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYNE3

    Search CenterWatch for drugs/clinical trials and news about SYNE3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYNE3 gene: 
    NM_152592.3  

    Unigene Cluster for SYNE3:

    Spectrin repeat containing, nuclear envelope family member 3
    Hs.354645  [show with all ESTs]
    Unigene Representative Sequence: NM_152592
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000334258 ENST00000554873 ENST00000557275(uc001yei.4 uc010avi.3)
    ENST00000555759 ENST00000553340(uc001yej.1)
    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SYNE3
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYNE3
    Clone
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    Primer
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    OriGene qPCR primer pairs and template standards for SYNE3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYNE3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYNE3

    Additional mRNA sequence: 

    AK098471.1 AK131436.1 BC146604.1 BX248076.1 

    5 DOTS entries:

    DT.91661516  DT.100694226  DT.101955820  DT.40255752  DT.99998396 

    22 AceView cDNA sequences:

    BX648302 NM_152592 BU149123 BX248076 AK131436 BU149126 BG236336 AK098471 
    CF137662 BC061899 BE675758 BX346277 BG111076 BX342493 BX325281 BM701154 
    AI648447 BF895767 BM715624 BQ358200 AA494024 BI829473 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SYNE3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:                                                                                      -                     
    SP2:                                                                                                            
    SP3:                                                                                                            


    ECgene alternative splicing isoforms for SYNE3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYNE3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SYNE3 Expression
    About this image


    See SYNE3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYNE3

    SOURCE GeneReport for Unigene cluster: Hs.354645

    UniProtKB/Swiss-Prot: SYNE3_HUMAN, Q6ZMZ3
    Tissue specificity: Expressed in aortic endothelial cells (at protein level)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYNE3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SYNE3 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syne31 , 5 RIKEN cDNA 4831426I19 gene5
    spectrin repeat containing, nuclear envelope family more1
    80.99(n)1
    77.7(a)1
      12 (54.97 cM)5
    2120731  NM_001042699.11  NP_001036164.11 
     1049299495 
    chicken
    (Gallus gallus)
    Aves C5H14orf491 chromosome 5 open reading frame, human C14orf49 62.1(n)
    54.69(a)
      423439  XM_421348.3  XP_421348.3 
    lizard
    (Anolis carolinensis)
    Reptilia SYNE36
    Uncharacterized protein
    52(a)
    1 ↔ 1
    1(7143618-7186686)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.296462 Xenopus laevis transcribed sequence 74.88(n)    CF271792.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1583271 zgc:158327 52.3(n)
    39.63(a)
      100009645  NM_001083014.1  NP_001076483.1 


    ENSEMBL Gene Tree for SYNE3 (if available)
    TreeFam Gene Tree for SYNE3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYNE3 gene
    1 SIMAP similar gene for SYNE3 using alignment to 2 protein entries:     SYNE3_HUMAN (see all proteins):
    C14orf49

    SYNE3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1612 SNPs in SYNE3 are shown (see all 1612)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1916151821,2
    --95883365(+) TGGGGA/GCTCGG 1 -- ds50010--------
    rs1827020721,2
    --95883430(+) CTGGGA/GTTAGG 1 -- ds50010--------
    rs27494741,2
    C,F--95883464(-) AGCACA/GGCTGT 1 -- ds500110Minor allele frequency- G:0.23NS EA WA NA CSA 784
    rs3735820271,2
    F,H--95883464(+) ACAGC-/C/TGTGCT 1 -- ds50014NS EA 378
    rs1873138281,2
    --95883515(+) CTCCCG/TCGATA 1 -- ds50010--------
    rs118474151,2
    C,F,A,H--95883516(+) TCCCTC/TGATAT 1 -- ds500122Minor allele frequency- T:0.06NS EA NA WA 2280
    rs1116492791,2
    C,F--95883566(+) TGGTCG/ATTGCC 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1180614031,2
    C,F--95883583(+) ACTTCT/CGACAC 1 -- ds50011Minor allele frequency- C:0.01NA 120
    rs765650271,2
    C,F--95883661(+) GAGTCA/G/TCTGGG 1 -- ds50012WA NA 238
    rs16311671,2
    C,F,H--95883698(+) TCCACG/CTTGCA 1 -- ds500119Minor allele frequency- C:0.20NS EA NA CSA WA 2219

    HapMap Linkage Disequilibrium report for SYNE3 (95883831 - 95942173 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SYNE3: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SYNE3
    DNA2.0 Custom Variant and Variant Library Synthesis for SYNE3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610861    OMIM disorders: --

    2 diseases for SYNE3:    About MalaCards
    endotheliitis    


    SYNE3 for disorders           About GeneDecksing


    Export disorders for SYNE3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYNE3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with SYNE3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. (PubMed id 16330710)1, 2, 9 Wilhelmsen K.... Sonnenberg A. (2005)
    2. Nesprin-3 regulates endothelial cell morphology, perin uclear cytoskeletal architecture, and flow-induced polarization. (PubMed id 21937718)1, 2 Morgan J.T....Barakat A.I. (2011)
    3. Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. (PubMed id 18396275)1, 2 Stewart-Hutchinson P.J.... Hodzic D. (2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    6. TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. (PubMed id 18827015)1, 9 Nery F.C....Breakefield X.O. (2008)
    7. A genome-wide association study of survival in small-c ell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. (PubMed id 23478653)1 Han J.Y....Lee J.S. (2013)
    8. Cytoskeletal interactions at the nuclear envelope mediated by nesprins. (PubMed id 22518138)2 Taranum S.... Noegel A.A. (2012)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 161176 HGNC: 19861 AceView: C14orf49 Ensembl:ENSG00000176438 euGenes: HUgn161176
    ECgene: SYNE3 H-InvDB: SYNE3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYNE3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYNE3 gene:
    Search GeneIP for patents involving SYNE3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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