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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYDE1 Gene

protein-coding   GIFtS: 51
GCID: GC19P015218

Synapse Defective 1, Rho GTPase, Homolog 1 (C. Elegans)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synapse Defective 1, Rho GTPase, Homolog 1 (C. Elegans)1 2     Rho GTPase-Activating Protein SYDE12
Protein Syd-1 Homolog 12 3     EC 2.4.1.258
Synapse Defective Protein 1 Homolog 12 3     EC 2.6.1.98
7h32     

External Ids:    HGNC: 258241   Entrez Gene: 853602   Ensembl: ENSG000001051377   UniProtKB: Q6ZW313   

Export aliases for SYDE1 gene to outside databases

Previous GC identifers: GC19P015080 GC19P014786


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SYDE1 Gene: 
SYDE1 (synapse defective 1, Rho GTPase, homolog 1 (C. elegans)) is a protein-coding gene. Diseases associated with SYDE1 include pancreatic cancer, and pancreatitis, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include Rho GTPase activator activity. An important paralog of this gene is ARHGAP29.

UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011295.11  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYDE1 gene promoter:
         USF1   GATA-3   Tal-1   Sp1   NRSF form 1   NRSF form 2   E47   GATA-1   RORalpha1   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYDE1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYDE1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYDE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

SYDE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYDE1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P015218:  view genomic region     (about GC identifiers)

Start:
15,218,214 bp from pter      End:
15,225,799 bp from pter
Size:
7,586 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31 (See protein sequence)
Recommended Name: Rho GTPase-activating protein SYDE1  
Size: 735 amino acids; 79793 Da
Secondary accessions: Q7L2I8 Q8N6J2 Q9H8K4
Alternative splicing: 2 isoforms:  Q6ZW31-1   Q6ZW31-2   

Explore the universe of human proteins at neXtProt for SYDE1: NX_Q6ZW31

Explore proteomics data for SYDE1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZW31

  • 2 DME Specific Peptides for SYDE1 (Q6ZW31)
     DFLRLDH  YGLGGLR 

    SYDE1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SYDE1 Protein Expression
    REFSEQ proteins: NP_149014.3  
    ENSEMBL proteins: 
     ENSP00000341489   ENSP00000473151   ENSP00000470733   ENSP00000469489   ENSP00000471553  
    Reactome Protein details: Q6ZW31
    Human Recombinant Protein Products for SYDE1: 
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    OriGene Protein Over-expression Lysate for SYDE1
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    Novus Biologicals SYDE1 Protein
    Novus Biologicals SYDE1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SYDE1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    SYDE1 for ontologies           About GeneDecksing



    SYDE1 Antibody Products: 
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    Assay Products for SYDE1: 
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    Cloud-Clone Corp. ELISAs for SYDE1 
    Cloud-Clone Corp. CLIAs for SYDE1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR008936 Rho_GTPase_activation_prot
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q6ZW31

    ProtoNet protein and cluster: Q6ZW31

    1 Blocks protein domain: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31
    Similarity: Contains 1 Rho-GAP domain


    SYDE1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYDE1_HUMAN, Q6ZW31
    Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
    similarity)

         Enzyme Numbers (IUBMB): EC 2.6.1.92 EC 2.4.1.252

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005100Rho GTPase activator activity ISS--
    GO:0005515protein binding ----
         
    SYDE1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SYDE1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SYDE1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYDE1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYDE1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYDE1
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate SYDE1 (see all 41):
    hsa-miR-582-3p hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-miR-429 hsa-miR-15a hsa-miR-3678-5p hsa-miR-128
    SwitchGear 3'UTR luciferase reporter plasmidSYDE1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for SYDE1
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                         Customized lentivirus expression plasmids for stable overexpression of SYDE1 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYDE1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SYDE1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for SYDE1
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    SYDE1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYDE1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SYDE1 (Q6ZW313 ENSP000003414894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KAT2AQ928303I2D: score=1 
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0032862activation of Rho GTPase activity ISS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    SYDE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYDE1

    Search CenterWatch for drugs/clinical trials and news about SYDE1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SYDE1 gene: 
    NM_033025.4  

    Unigene Clusters for SYDE1:

    Synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
    Hs.528701  [show with all ESTs], Hs.706845
    Unigene Representative Sequences: AK128870, AF209931
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000342784(uc002nah.1 uc002nai.1 uc002naj.1) ENST00000597977
    ENST00000600440 ENST00000600252 ENST00000602203
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYDE1
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate SYDE1 (see all 41):
    hsa-miR-582-3p hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-miR-429 hsa-miR-15a hsa-miR-3678-5p hsa-miR-128
    SwitchGear 3'UTR luciferase reporter plasmidSYDE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SYDE1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYDE1
    Clone
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    OriGene clones in human, mouse for SYDE1 (see all 6)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYDE1 (NM_033025)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYDE1
    Sirion Biotech Customized lentivirus for stable overexpression of SYDE1 
                         Customized lentivirus expression plasmids for stable overexpression of SYDE1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SYDE1
    OriGene qSTAR qPCR primer pairs in human, mouse for SYDE1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SYDE1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SYDE1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYDE1

    Additional mRNA sequence: AF209931.1 

    7 DOTS entries:

    DT.102829576  DT.97840367  DT.99983997  DT.92423261  DT.100687945  DT.121420810  DT.92414134 

    24/133 AceView cDNA sequences (see all 133):

    BC029926 BE383218 BQ772813 AA031652 AW304767 BM916657 BU166010 AW952588 
    CA397878 AA336131 BM471755 AI468730 BF194914 AA434382 AI559356 AI031701 
    BF935858 BM462004 BQ010378 AI521921 BQ446650 AA723414 AK128870 BI257718 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SYDE1 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                                              
    SP2:                                                                              
    SP3:        -                                                                     
    SP4:                                                              -               
    SP5:                                                                              


    ECgene alternative splicing isoforms for SYDE1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYDE1 expression in normal human tissues (normalized intensities)      SYDE1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGTATGTG
    SYDE1 Expression
    About this image


    SYDE1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Endothelium (Cardiovascular System)
             aorta   
     
     Adipose (Muscoskeletal System)
             epididymal fat pads   
     
     Lung (Respiratory System)

    See SYDE1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYDE1

    SOURCE GeneReport for Unigene clusters: Hs.528701 Hs.706845
        SABiosciences Custom PCR Arrays for SYDE1
    Primer
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYDE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SYDE1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syde11 , 5 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)1, 5 82.31(n)1
    87.48(a)1
      10 (39.72 cM)5
    717091  NM_027875.11  NP_082151.11 
     785845035 
    chicken
    (Gallus gallus)
    Aves LOC4298921 rho GTPase-activating protein SYDE1-like 63.85(n)
    59.46(a)
      429892  XM_427446.3  XP_427446.3 
    lizard
    (Anolis carolinensis)
    Reptilia SYDE16
    Uncharacterized protein
    51(a)
    1 ↔ 1
    2(80126935-80188054)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5681661 rho GTPase-activating protein SYDE2-like 59.56(n)
    56.21(a)
      568166  XM_691479.5  XP_696571.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta RhoGAP100F6
    RhoGAP100F
    11(a)
    1 → many
    3R(27638331-27670966)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RGD16
    GTPase-activating protein (RhoGAP) for Rho3p and R...
    9(a)
    1 → many
    II(732639-734639)


    ENSEMBL Gene Tree for SYDE1 (if available)
    TreeFam Gene Tree for SYDE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYDE1 gene
    ARHGAP292  SYDE22  HMHA12  RACGAP12  ABR2  GMIP2  BCR2  
    4 SIMAP similar genes for SYDE1 using alignment to 4 protein entries:     SYDE1_HUMAN (see all proteins):
    ARHGAP21    ARHGAP12    ARHGAP9    FAM13A

    SYDE1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/237 SNPs in SYDE1 are shown (see all 237)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0626614
    A pancreatic ductal adenocarcinoma sample4--see VAR_0626612 R Q mis40--------
    rs1853956701,2
    --15147477(+) ATCATA/GTAAAC 1 -- us2k10--------
    rs126111031,2
    C,F,H--15147511(+) caataA/Gattta 1 -- us2k110Minor allele frequency- G:0.42NA WA EA 374
    rs28867391,2
    C,F,A,H--15147540(-) tgtccT/Ataacc 1 -- us2k113Minor allele frequency- A:0.11NA WA CSA EA 379
    rs1161582501,2
    F--15147557(+) TGACAC/GAGACT 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1899549061,2
    --15147637(+) TACTTC/GGTAGG 1 -- us2k10--------
    rs124594461,2
    C,F,A,H--15147706(+) ttttgA/Tttttt 1 -- us2k13Minor allele frequency- T:0.33NA 6
    rs1833174421,2
    --15147789(+) CTCCCA/GGGTTC 1 -- us2k10--------
    rs1865552341,2
    --15147888(+) AGGGGA/TTTCCC 1 -- us2k10--------
    rs713347601,2
    C,F--15147949(+) CTTGGC/TCTCCC 1 -- us2k12Minor allele frequency- T:0.50NA 4

    HapMap Linkage Disequilibrium report for SYDE1 (15218214 - 15225799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SYDE1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34154CNV Loss18971310
    nsv911130CNV Loss21882294
    nsv9668CNV Gain18304495
    dgv1058e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SYDE1
    DNA2.0 Custom Variant and Variant Library Synthesis for SYDE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SYDE1:    About MalaCards
    pancreatic cancer    pancreatitis


    SYDE1 for disorders           About GeneDecksing


    Export disorders for SYDE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYDE1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SYDE1)
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    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    4. Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. (PubMed id 19531213)1 Havrylov S....Redowicz M.J. (2009)
    5. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    6. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. (PubMed id 18772397)2 Jones S.... Kinzler K.W. (2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 85360 HGNC: 25824 AceView: 7h3 Ensembl:ENSG00000105137 euGenes: HUgn85360
    ECgene: SYDE1 H-InvDB: SYDE1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYDE1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SYDE1 gene:
    Search GeneIP for patents involving SYDE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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