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SYDE1 Gene

protein-coding   GIFtS: 50
GCID: GC19P015218

Synapse Defective 1, Rho GTPase, Homolog 1 (C. Elegans)

  Search for SYDE1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synapse Defective 1, Rho GTPase, Homolog 1 (C. Elegans)1 2     Rho GTPase-Activating Protein SYDE12
Protein Syd-1 Homolog 12 3     EC 2.4.1.258
Synapse Defective Protein 1 Homolog 12 3     EC 2.6.1.98
7h32     

External Ids:    HGNC: 258241   Entrez Gene: 853602   Ensembl: ENSG000001051377   UniProtKB: Q6ZW313   

Export aliases for SYDE1 gene to outside databases

Previous GC identifers: GC19P015080 GC19P014786


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SYDE1 Gene:
SYDE1 (synapse defective 1, Rho GTPase, homolog 1 (C. elegans)) is a protein-coding gene. GO annotations related to this gene include Rho GTPase activator activity. An important paralog of this gene is SYDE2.

UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYDE1 gene promoter:
         USF1   GATA-3   Tal-1   Sp1   NRSF form 1   NRSF form 2   E47   GATA-1   RORalpha1   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSYDE1 promoter sequence
   Search Chromatin IP Primers for SYDE1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYDE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

SYDE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYDE1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P015218:  view genomic region     (about GC identifiers)

Start:
15,218,214 bp from pter      End:
15,225,799 bp from pter
Size:
7,586 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31 (See protein sequence)
Recommended Name: Rho GTPase-activating protein SYDE1  
Size: 735 amino acids; 79793 Da
Secondary accessions: Q7L2I8 Q8N6J2 Q9H8K4
Alternative splicing: 2 isoforms:  Q6ZW31-1   Q6ZW31-2   

Explore the universe of human proteins at neXtProt for SYDE1: NX_Q6ZW31

Explore proteomics data for SYDE1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for SYDE1 (Q6ZW31)
     DFLRLDH  YGLGGLR 


    See SYDE1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_149014.3  
    ENSEMBL proteins: 
     ENSP00000341489   ENSP00000473151   ENSP00000470733   ENSP00000469489   ENSP00000471553  
    Reactome Protein details: Q6ZW31

    SYDE1 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for SYDE1
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    Novus Biologicals SYDE1 Protein
    Novus Biologicals SYDE1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SYDE1

     
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    LSBio Antibodies in human, mouse, rat for SYDE1

    SYDE1 Assay Products:

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    Cloud-Clone Corp. ELISAs for SYDE1
    Cloud-Clone Corp. CLIAs for SYDE1
    Search eBioscience for ELISAs for SYDE1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q6ZW31

    ProtoNet protein and cluster: Q6ZW31

    1 Blocks protein domain: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: SYDE1_HUMAN, Q6ZW31
    Similarity: Contains 1 Rho-GAP domain


    Find genes that share domains with SYDE1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYDE1_HUMAN, Q6ZW31
    Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
    similarity)

         Enzyme Numbers (IUBMB): EC 2.6.1.92 EC 2.4.1.252

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005100Rho GTPase activator activity ISS--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with SYDE1           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Syde1):
     nervous system 

    Find genes that share phenotypes with SYDE1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYDE1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SYDE1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYDE1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYDE1

    miRNA
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    Block miRNA regulation of human, mouse, rat SYDE1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SYDE1 (see all 41):
    hsa-miR-582-3p hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-miR-429 hsa-miR-15a hsa-miR-3678-5p hsa-miR-128
    SwitchGear 3'UTR luciferase reporter plasmidSYDE1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SYDE1
    Predesigned siRNA for gene silencing in human, mouse, rat SYDE1

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYDE1 (NM_033025)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYDE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYDE1

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for SYDE1 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYDE1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    Find genes that share ontologies with SYDE1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SYDE1 About    
    See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.58


    Find genes that share SuperPaths with SYDE1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SYDE1
        Rho GTPase cycle


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYDE1
    Interactions:

        Search GeneGlobe Interaction Network for SYDE1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SYDE1 (Q6ZW313 ENSP000003414894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KAT2AQ928303I2D: score=1 
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0032862activation of Rho GTPase activity ISS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    Find genes that share ontologies with SYDE1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYDE1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYDE1 gene: 
    NM_033025.4  

    Unigene Cluster for SYDE1:

    Synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
    Hs.528701  [show with all ESTs]
    Unigene Representative Sequence: AK128870
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000342784(uc002nah.1 uc002nai.1 uc002naj.1) ENST00000597977
    ENST00000600440 ENST00000600252 ENST00000602203
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SYDE1 (see all 41):
    hsa-miR-582-3p hsa-miR-520e hsa-miR-302d hsa-miR-136 hsa-miR-429 hsa-miR-15a hsa-miR-3678-5p hsa-miR-128
    SwitchGear 3'UTR luciferase reporter plasmidSYDE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SYDE1
    Predesigned siRNA for gene silencing in human, mouse, rat SYDE1
    Clone
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    OriGene ORF clones in mouse, rat for SYDE1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYDE1 (NM_033025)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYDE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYDE1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SYDE1
    OriGene qSTAR qPCR primer pairs in human, mouse for SYDE1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SYDE1
      QuantiTect SYBR Green Assays in human, mouse, rat SYDE1
      QuantiFast Probe-based Assays in human, mouse, rat SYDE1

    Additional mRNA sequence: 

    AK023573.1 AK123686.1 AK128870.1 AK315453.1 BC018942.2 BC029926.1 

    7 DOTS entries:

    DT.97840367  DT.102829576  DT.99983997  DT.92423261  DT.100687945  DT.121420810  DT.92414134 

    Selected AceView cDNA sequences (see all 133):

    CA397878 AW952588 AW304767 BC029926 BM916657 BQ772813 AA031652 AI468730 
    BU166010 BE383218 BM471755 AA336131 BI061524 BU632848 BF339476 AI031701 
    BM972868 BU147073 CO246055 BQ010378 AK123686 NM_033025 BF305306 BU169236 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SYDE1 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                                              
    SP2:                                                                              
    SP3:        -                                                                     
    SP4:                                                              -               
    SP5:                                                                              


    ECgene alternative splicing isoforms for SYDE1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYDE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGTATGTG
    SYDE1 Expression
    About this image

    SYDE1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYDE1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.528701
        Custom PCR Arrays for SYDE1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYDE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SYDE1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syde11 , 5 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)1, 5 82.31(n)1
    87.48(a)1
      10 (39.72 cM)5
    717091  NM_027875.11  NP_082151.11 
     785845035 
    chicken
    (Gallus gallus)
    Aves SYDE11 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 64.96(n)
    61.49(a)
      429892  XM_427446.4  XP_427446.4 
    lizard
    (Anolis carolinensis)
    Reptilia SYDE16
    synapse defective 1, Rho GTPase, homolog 1 (C. ele...
    52(a)
    1 ↔ 1
    2(80126935-80188054)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5681661 rho GTPase-activating protein SYDE2-like 58.5(n)
    54.32(a)
      568166  XM_691479.6  XP_696571.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta RhoGAP100F6
    RhoGAP100F
    12(a)
    1 → many
    3R(27638331-27670966)
    worm
    (Caenorhabditis elegans)
    Secernentea syd-16
    Protein SYD-1, isoform a
    15(a)
    1 → many
    II(7585731-7594912) WBGene00006363
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BEM26
    Rho GTPase activating protein (RhoGAP) involved in...
    5(a)
    1 → many
    V(476345-482848) YER155C


    ENSEMBL Gene Tree for SYDE1 (if available)
    TreeFam Gene Tree for SYDE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYDE1 gene
    SYDE22  RACGAP12  ABR2  BCR2  
    4 SIMAP similar genes for SYDE1 using alignment to 4 protein entries:     SYDE1_HUMAN (see all proteins):
    ARHGAP21    ARHGAP12    ARHGAP9    FAM13A

    Find genes that share paralogs with SYDE1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYDE1 (see all 237)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0626614
    A pancreatic ductal adenocarcinoma sample4--see VAR_0626612 R Q mis40--------
    rs1853956701,2
    --15147477(+) ATCATA/GTAAAC 1 -- us2k10--------
    rs126111031,2
    C,F,H--15147511(+) caataA/Gattta 1 -- us2k110Minor allele frequency- G:0.42NA WA EA 374
    rs28867391,2
    C,F,A,H--15147540(-) tgtccT/Ataacc 1 -- us2k113Minor allele frequency- A:0.11NA WA CSA EA 379
    rs1161582501,2
    F--15147557(+) TGACAC/GAGACT 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1899549061,2
    --15147637(+) TACTTC/GGTAGG 1 -- us2k10--------
    rs124594461,2
    C,F,A,H--15147706(+) ttttgA/Tttttt 1 -- us2k13Minor allele frequency- T:0.33NA 6
    rs1833174421,2
    --15147789(+) CTCCCA/GGGTTC 1 -- us2k10--------
    rs1865552341,2
    --15147888(+) AGGGGA/TTTCCC 1 -- us2k10--------
    rs713347601,2
    C,F--15147949(+) CTTGGC/TCTCCC 1 -- us2k12Minor allele frequency- T:0.50NA 4

    HapMap Linkage Disequilibrium report for SYDE1 (15218214 - 15225799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SYDE1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv34154CNV Loss18971310
    nsv911130CNV Loss21882294
    nsv9668CNV Gain18304495
    dgv1058e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYDE1
    DNA2.0 Custom Variant and Variant Library Synthesis for SYDE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYDE1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SYDE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    4. Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. (PubMed id 19531213)1 Havrylov S....Redowicz M.J. (Proteome Sci 2009)
    5. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    6. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. (PubMed id 18772397)2 Jones S.... Kinzler K.W. (Science 2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 85360 HGNC: 25824 AceView: 7h3 Ensembl:ENSG00000105137 euGenes: HUgn85360
    ECgene: SYDE1 H-InvDB: SYDE1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SYDE1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SYDE1 gene:
    Search GeneIP for patents involving SYDE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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